Phascolarctos cinereus (koala): 110210616
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Entry
110210616 CDS
T05867
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00230
Purine metabolism
pcw01100
Metabolic pathways
pcw04022
cGMP-PKG signaling pathway
pcw04740
Olfactory transduction
pcw04925
Aldosterone synthesis and secretion
pcw05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110210616 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
110210616 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
110210616 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
110210616 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110210616 (PDE2A)
Enzymes [BR:
pcw01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
110210616 (PDE2A)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
Motif
Other DBs
NCBI-GeneID:
110210616
NCBI-ProteinID:
XP_020845306
UniProt:
A0A6P5KLG8
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All DBs
Position
Unknown
AA seq
953 aa
AA seq
DB search
MGQACGHSILCRSQQCPARPGEPEPRGQQVFLKPDEEPPPSQPQQQPCADTLQEALLSLG
SVIDVSSLHDVIKEAISAVLPKVETVYTYLLDGESRLVCADPPHDLPQEGKVRDAVQAWE
RLSCSGLGPSDLPEKALTGLTAPLAADRQVLVVPLVDKEAGGVVATVLVHCAQLSEGDEQ
SLQAIEKHTLVALKRLRTLQQRQPHTRPVPEPSSPPTSLARPDGAMPIGTGGYSDLDSRI
LQLCGELYDLDASSLQLKVLHYLQQETESSTCCLLLVSEDNLQLSCQVIGDKVLGEEVSF
PMTVGSLGQVVKNKESITLKDLTSEEVTQLQSLVGCELQSMLCVPVISRATNQVVALACT
FNKQGGETYTDWDEHKILHCFCYTATVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDD
VSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDETYEIRIPADQGIAGHV
ATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWF
SKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYDKLLGDG
IQPVSAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDRQTLVRFCLMVKKG
YRDPPYHNWMHAFSVSHFCYLLCKNLELSKYLDDIEIFALFVSCMCHDLDHRGTNNSFQV
ASKSVLAALYSSEGSVMERHHFAQAIAILNTQGCNIFDHFSRKDYQRMLDLMRDIILATD
LAHHLRIFKDLQKMAEVGYDPKNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKE
FFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQELFPRAAELYERVA
TNREQWTKVSHKFTIRGLPSNNSLDFLDEEYDIQEPGDDGDKVNGCCKLDAEE
NT seq
2862 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcgtgcggccactccatcctgtgccggagccagcagtgcccggcgcggccc
ggggagcccgagccgcggggccagcaggtcttcctgaagccggacgaggagccgccgccg
tcacagccgcagcagcagccttgcgccgacaccctgcaggaagccctgctgagtttgggc
tctgtcattgatgtctctagtcttcacgatgtcatcaaagaagccatctctgctgtgctc
cccaaagtggaaaccgtctacacttacctacttgatggagaatcccggctggtgtgtgca
gaccccccacatgatctaccccaggaggggaaagttcgagatgccgtccaggcctgggag
cggctgagctgcagtgggctgggcccctcagacttgccagagaaagcattgacggggctc
actgccccactggctgctgacagacaagtgctggtagtcccattggtggacaaggaagct
ggaggtgttgtggccaccgtcctggtacactgtgcacaactcagcgagggggatgagcag
agcttgcaggccatagagaagcacaccctagtggccctgaagaggcttcggaccctgcag
cagcgtcagccccatacccggccggtgccagagccctcttccccacccacttcgctggcc
cggccggatggggccatgcctattgggacaggtggctacagtgacctggacagccggatt
ctgcagctgtgtggggagctctatgacctggatgcctcttcccttcagctcaaagtactc
cattatttgcagcaggagactgagtcctcaacctgctgcctcctccttgtttcagaggat
aaccttcagctttcctgccaggtcatcggagacaaagtgcttggagaagaagtcagtttt
ccaatgacagtggggagcctgggccaggtggtaaagaacaaggaatccatcacattgaag
gacctcacttcagaagaggtgacacagctgcagagcctcgtgggatgtgagctgcagtcc
atgctctgtgtccctgtcatcagccgggctacaaatcaggtggtagccttagcctgcact
ttcaacaagcagggaggagagacgtacacggactgggatgagcacaagatactccactgt
ttctgctacacagctacggtccttaccagcaccctggccttccagaaggaacagaagctc
aagtgtgagtgccaggctcttctccaagtggcaaagaacctcttcacacacttggatgat
gtctctgtcctgctccaagaaatcatcacagaagcccggaacctcagcaatgctgagatc
tgctccgtgttcctattggatcagaatgagctggtggccaaggtgtttgatggtggtgtt
gtggatgatgagacctatgagatacgaatccctgcagaccaagggattgcaggtcatgtg
gccaccacaggccagatcctgaacatcccggatgcctatgcacatcccctgttctaccga
ggtgtggacgacagcacgggcttccgcacacgcaacatactctgcttccctatcaagaat
gaaaaccaagaggtcatcggtgtggctgagctggtgaacaagatcaatggcccttggttc
agcaagtttgatgaggacctggccacagccttttccatctactgcggcatcagcatcgct
cattctcttctatacaagaaagtgaatgaagcccagtatcggagccacttggccaatgag
atgatgatgtatcacatgaaggtgtcagatgatgagtatgacaagctccttggagatggg
atccagccagtctcagccattgactccaactttgccagtttcacctacaccccacgctct
ctccctgaggatgacacctccatggccatcctgagtatgctccaggacatgaactttatc
aacaactacaagattgaccgacagacattggtccggttctgcctgatggtgaagaagggc
taccgagaccctccgtatcacaactggatgcacgccttctctgtctcccacttttgctac
ctgctctgtaagaacctggagctgtccaaatatctagatgacatcgagatcttcgccttg
tttgtctcctgcatgtgccatgacctggaccacagaggcaccaacaattccttccaggtg
gcttcgaaatccgtgctggccgcgttgtacagctccgaaggctccgtcatggagagacac
cactttgctcaggcgattgccatcctcaatacccaaggttgcaacatctttgatcacttc
tcccgcaaggactaccagcggatgctggatctgatgagagacattatcttggctactgac
ctagcccaccacctgcgcatcttcaaagaccttcagaagatggctgaagtgggttatgac
ccaaagaataaacaacaccacagccttctgctctgcctgctcatgacctcctgtgacctc
tcagaccagaccaagggctggaagaccacgcggaagattgcagagctgatctacaaggag
ttcttctcacagggagacctggagaaggccatgggtaaccggcccatggagatgatggat
cgagagaaggcttatatccctgagctccagatcagcttcatggagcacattgccatgcca
atctacaagctgctgcaggagttgtttccccgagctgcagaactgtatgagcgggtcgcc
accaaccgggagcagtggaccaaggtgtcacataagttcactattcgaggcctgcccagc
aacaactctctggacttcctggatgaggaatacgacattcaggagccgggtgatgatggt
gacaaggtcaatgggtgctgcaagttggacgcggaagagtga
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