Phascolarctos cinereus (koala): 110210635
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Entry
110210635 CDS
T05867
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110210635 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pcw01002
]
110210635 (BACE1)
Enzymes [BR:
pcw01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
110210635 (BACE1)
Peptidases and inhibitors [BR:
pcw01002
]
Aspartic peptidases
Family A1: pepsin family
110210635 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
110210635
NCBI-ProteinID:
XP_020845343
UniProt:
A0A6P5KIC9
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All DBs
Position
Unknown
AA seq
496 aa
AA seq
DB search
MAQALPWVLLWMGSGVLCTQPGIRLPLKSGLSLGLRLPREAIEELDESSRRSSFVEMVDN
LRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYRRQLSSTYRDLRK
GVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAE
IARPDESLEPFFDSLVKQTQVPNLFSLQLCGTGFPSLNQSEAMASVGGSMIIGGIDHSLY
VGSLWYTPIRREWYYEVVIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
VKSIKTASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQ
YLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAHKRIGFGVSACHVHDE
FRTAAVEGPFVIADMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRC
LRRQQDDFADDISLLK
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atggctcaagccctgccctgggtcttgctgtggatgggctcaggggtgttgtgcacccag
ccaggaatccggctccccctgaagagtggactctccttgggtctccggctgcctcgggag
gccatcgaggaactggatgagtccagccgcagaagcagttttgtagagatggtggacaac
ctgagaggcaagtctggtcaaggctactacgtggaaatgacagtgggcagtcctccacag
acgctcaacatcctagtggacacaggcagcagtaactttgcagtaggagctgcccctcac
cctttcttacatcgatactaccggagacagctatccagcacctatcgagacttacggaag
ggtgtatacgtgccctacacccaaggcaagtgggagggcgagctgggcactgacctagta
agcatccctcatggcccaaatgtcaccgtacgtgccaacattgctgccatcactgagtct
gacaagttcttcatcaatggctctaactgggagggcatcctgggactggcttatgctgag
attgccaggcccgatgagagcctggagcccttctttgactctctggtgaagcagacccaa
gtacccaacctcttctccctacagctgtgtggcacgggcttcccaagcctcaaccagtct
gaggcaatggcctcagttggcgggagcatgatcattgggggcattgaccattccctatat
gtgggcagtctgtggtacacaccgatccgacgagaatggtactatgaagttgtcattgtt
cgggtggagatcaatgggcaggacctgaaaatggactgtaaggagtacaactatgacaag
agtattgtggacagtggcaccaccaacctgagactgcccaagaaagtgtttgaggctgca
gtcaagtccatcaagacagcctcctcgacagagaaattcccagatggcttctggctaggg
gagcagctggtgtgctggcaagctggcactaccccctggaacatcttcccagtcatctca
ctctacctaatgggtgaagtcactaatcagtccttccgaatcaccattctgccacagcaa
tacctaaggccagtggaggacgttgccacgtctcaagatgactgctacaagtttgccatc
tcacaatcatccacgggcactgttatgggagctgtgatcatggaaggcttctacgttgtc
tttgacagagcccacaaacgaattggctttggtgtcagtgcctgccacgtgcacgacgag
ttccggacagcagcagtggaaggcccctttgttatcgcagacatggaggactgtggctac
aacattccacagacagatgagtcgaccctcatgaccatcgcctacgtcatggccgccatc
tgtgctctcttcatgcttccactctgcctcatggtgtgccagtggcgctgcctccgctgc
ctgcgccgccagcaggatgactttgctgatgacatctctctgctcaagtga
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