KEGG   Phascolarctos cinereus (koala): 110212045
Entry
110212045         CDS       T05867                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw01521  EGFR tyrosine kinase inhibitor resistance
pcw01522  Endocrine resistance
pcw04012  ErbB signaling pathway
pcw04066  HIF-1 signaling pathway
pcw04140  Autophagy - animal
pcw04150  mTOR signaling pathway
pcw04151  PI3K-Akt signaling pathway
pcw04152  AMPK signaling pathway
pcw04211  Longevity regulating pathway
pcw04213  Longevity regulating pathway - multiple species
pcw04350  TGF-beta signaling pathway
pcw04371  Apelin signaling pathway
pcw04666  Fc gamma R-mediated phagocytosis
pcw04714  Thermogenesis
pcw04910  Insulin signaling pathway
pcw04931  Insulin resistance
pcw05163  Human cytomegalovirus infection
pcw05165  Human papillomavirus infection
pcw05170  Human immunodeficiency virus 1 infection
pcw05200  Pathways in cancer
pcw05205  Proteoglycans in cancer
pcw05207  Chemical carcinogenesis - receptor activation
pcw05210  Colorectal cancer
pcw05212  Pancreatic cancer
pcw05221  Acute myeloid leukemia
pcw05224  Breast cancer
pcw05225  Hepatocellular carcinoma
pcw05226  Gastric cancer
pcw05231  Choline metabolism in cancer
pcw05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    110212045 (RPS6KB1)
   04350 TGF-beta signaling pathway
    110212045 (RPS6KB1)
   04371 Apelin signaling pathway
    110212045 (RPS6KB1)
   04066 HIF-1 signaling pathway
    110212045 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    110212045 (RPS6KB1)
   04152 AMPK signaling pathway
    110212045 (RPS6KB1)
   04150 mTOR signaling pathway
    110212045 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110212045 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    110212045 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    110212045 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    110212045 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    110212045 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    110212045 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110212045 (RPS6KB1)
   05205 Proteoglycans in cancer
    110212045 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    110212045 (RPS6KB1)
   05231 Choline metabolism in cancer
    110212045 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110212045 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110212045 (RPS6KB1)
   05212 Pancreatic cancer
    110212045 (RPS6KB1)
   05225 Hepatocellular carcinoma
    110212045 (RPS6KB1)
   05226 Gastric cancer
    110212045 (RPS6KB1)
   05221 Acute myeloid leukemia
    110212045 (RPS6KB1)
   05224 Breast cancer
    110212045 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110212045 (RPS6KB1)
   05163 Human cytomegalovirus infection
    110212045 (RPS6KB1)
   05165 Human papillomavirus infection
    110212045 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110212045 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110212045 (RPS6KB1)
   01522 Endocrine resistance
    110212045 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcw01001]
    110212045 (RPS6KB1)
Enzymes [BR:pcw01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     110212045 (RPS6KB1)
Protein kinases [BR:pcw01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   110212045 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 110212045
NCBI-ProteinID: XP_020847484
UniProt: A0A6P5KRI9
LinkDB
Position
Unknown
AA seq 547 aa
MRRRRRRDGFYPAPDFRDGEAEAMAGVFDIDLDQPEDAGSEDELEEGGQLSESMDHGGVG
PYEIGMEHCEKFEISETSVNKGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGATTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGGDNSKQFYSH
VKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAP
PFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPF
FRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGF
TYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASAATTQTP
VDYPMETSGIEQMDVTWFFFLLSQVGFATIYQNKLFSCLTRSGVRVTPFLLFILYLVYCN
KIYFISE
NT seq 1644 nt   +upstreamnt  +downstreamnt
atgaggcggcggcggcggcgggacggattttacccagcgccagacttcagagacggggaa
gctgaggccatggccggagtttttgacatcgacctggaccagccggaggacgcaggctct
gaggatgagctggaggaagggggtcaattaagtgaaagcatggaccatgggggagttgga
ccatatgaaattggcatggaacattgtgaaaaatttgaaatctcagaaactagtgtgaac
aaagggccagaaaaaataagaccagaatgttttgagctacttcgagtacttggtaaaggg
ggctatggaaaggttttccaagtacgaaaagtaacaggagcaactactgggaaaatattt
gcgatgaaggtgcttaaaaaggctatgatagtaagaaatgcgaaagatacagctcataca
aaagcagaacgaaatatccttgaggaagtaaagcatcccttcattgtggacttaatttat
gcctttcagactggtggaaaactctacctcatcctggagtatctcagtggaggagaatta
tttatgcagttagaaagagagggaatatttatggaagatacagcttgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaagggatcatctacagagacctgaag
ccggaaaatatcatgcttaatcaccaaggtggagataacagtaaacaattctatagtcat
gtgaaattgacggactttggactatgcaaagaatccattcatgatggaacagtcacacac
acgttctgtggaacaatagaatacatggctcctgaaatcttgatgagaagtggccataat
cgtgctgtggactggtggagtttgggggcattaatgtatgacatgctgactggagcaccc
ccatttactggggagaacagaaagaagacaattgacaaaatcctcaaatgtaaacttaat
ttgcctccctacctcacacaagaagccagagatctgcttaaaaagctgctaaaaagaaat
gctgcttcgcgtcttggagctggtcctggggatgctggagaagttcaggctcatcctttc
ttcagacacattaactgggaagaacttctggctcggaaggtggagcctccctttaaacct
cttttgcaatctgaagaggatgtgagccagtttgattcaaagtttacacgtcagacacct
gttgacagcccagatgactcaactctcagtgaaagtgccaaccaggtctttctgggtttt
acatatgtggctccatctgtacttgaaagcgtgaaagaaaaattttcatttgaaccaaaa
atccgatcacctcgaagattcattggcagccctcggacacctgtcagcccagtcaaattt
tctcctggggatttctggggaagaggtgcttcagccagtgcagcaactactcagacacct
gtggattatcccatggaaacgagtggaatagaacaaatggatgtgacgtggttctttttt
ctgctatcccaagttggctttgcaaccatctatcaaaataaattattcagctgccttact
aggagtggtgtgagggtaacaccttttctgcttttcatcttgtatttagtttactgtaat
aaaatatactttatttcagaatga

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