Phascolarctos cinereus (koala): 110214168
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Entry
110214168 CDS
T05867
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw04217
Necroptosis
pcw04380
Osteoclast differentiation
pcw04620
Toll-like receptor signaling pathway
pcw04621
NOD-like receptor signaling pathway
pcw04630
JAK-STAT signaling pathway
pcw04658
Th1 and Th2 cell differentiation
pcw04659
Th17 cell differentiation
pcw05145
Toxoplasmosis
pcw05160
Hepatitis C
pcw05161
Hepatitis B
pcw05162
Measles
pcw05164
Influenza A
pcw05165
Human papillomavirus infection
pcw05167
Kaposi sarcoma-associated herpesvirus infection
pcw05168
Herpes simplex virus 1 infection
pcw05169
Epstein-Barr virus infection
pcw05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110214168 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
110214168 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110214168 (TYK2)
04621 NOD-like receptor signaling pathway
110214168 (TYK2)
04658 Th1 and Th2 cell differentiation
110214168 (TYK2)
04659 Th17 cell differentiation
110214168 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
110214168 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
110214168 (TYK2)
05160 Hepatitis C
110214168 (TYK2)
05171 Coronavirus disease - COVID-19
110214168 (TYK2)
05164 Influenza A
110214168 (TYK2)
05162 Measles
110214168 (TYK2)
05168 Herpes simplex virus 1 infection
110214168 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
110214168 (TYK2)
05169 Epstein-Barr virus infection
110214168 (TYK2)
05165 Human papillomavirus infection
110214168 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110214168 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110214168 (TYK2)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110214168 (TYK2)
Protein kinases [BR:
pcw01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110214168 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kinase-like
Kdo
RA
ABC1
RA_2
Motif
Other DBs
NCBI-GeneID:
110214168
NCBI-ProteinID:
XP_020850576
UniProt:
A0A6P5L4P9
LinkDB
All DBs
Position
Unknown
AA seq
1197 aa
AA seq
DB search
MPLCHCAARHSDSDGDWGYPSSSGIKVFLHWSNGGDQYVTYNQGTMTAEEVCIHIAQKVG
ITPLCYNLFALYDAQAQIWLPPNHPFEITKDTNQTLQFRMRYYFRNWHGLNSQEPAVYRS
MPQGVEVSEEKTSTEQGCALLDKASFEYLYEQGKFEFVNDVASLSDLHSEAEIHYFKNES
LGMAVLHLSHLALQRGVPLEEVVRKTSFKDCIPRSFSRQIQQNNSLTKFRLRNVFQKFMR
RFHLQTVGPGRLSERDIMFKYLATLEQLAPRFGTEHFLALTLALATEAERDLCYVNSSEQ
GPTVPPGATLSLADRAPSHEVRVTGTSGIHWRLLQVEDPDLDVNHPRGSFRKKSKAREAE
SRKPSQLPTERKESPWMYFCDFQDITHVVVKENNVSIHRQDNKCLELTLLSPMVALSLVS
LVDGYFRLTADSSHYLCREVAPPRLVMSVQNGIHGPLQEPYVLSKLKREEVEDGLYLIRW
SSFDFHRLILTVARKDQTSGAQGLRYKQFRIEERGLTFQLEGWDQAFSSVRELTAALQGC
TLRSSSGSGPGSSLESFTLSKCCLPRAGEISNLIITRQRPKEGPKPLNLSQLSFHQIRKE
EITQLAHLGQGTRTNIYEGLLRVGGGMGAEDEEEENIPSEPNNNHRELRVVLKVLDPSHR
DIALAFFETASLMSQVSHIHLAFVHGVCVRGSENIMVAEHVEHGPLDVCLRREKGHVPVA
WKITVAQQLASALSYLEDKNLVHGNVCGKNILLARRGLGDGTQPFIKLSDPGVSVTALSR
EERAERIPWIAPECVPSGTGLSTAADKWSFGTTLLEICFDGEAPLQGRTPSEKERFYEKK
HRLPEPSCKELATLISQCLTHEANQRPSFRTILRDLTQLQPQNLADITTVSPEFPASDPT
VFQKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKSLKAGCSSQLLSSWQREIEI
LRTLYHEHIVKYKGCCSDQGEKMVQLIMEYVPLGSLRDYLPKHSLGLAQILLFAQQICEG
MAYLHSQHYIHRDLAARNVLLENDNTVKIGDFGLAKAVPEGHDYYCVQEDGDSPVFWYAM
ECLKECKFYYASDVWSFGVTLYELLTRCDCNQTPPLKFIEMIGVTQGQMTVLRLIDLLER
GQRLPCPKDCPSEIYLLMKNCWEYEASFRPTFQNLVPLLRTFHEKYRNQAPSVFSVC
NT seq
3594 nt
NT seq
+upstream
nt +downstream
nt
atgccactatgtcactgtgctgcaagacacagtgattccgatggggactggggctaccct
agcagcagtgggatcaaggttttcctccactggagcaatgggggtgaccagtatgtgacc
tacaaccagggcaccatgactgcagaggaagtctgcattcatattgcacagaaagtgggg
atcaccccactctgctacaaccttttcgcattatatgatgcccaggcccaaatctggctc
cctcctaaccacccctttgagatcaccaaggacaccaaccagaccctacaatttcgaatg
aggtattacttccgaaactggcatggtctgaacagccaggaaccagccgtgtaccgaagc
atgcctcagggtgttgaggtctctgaagagaagacctcgacggagcaagggtgtgctttg
ctggacaaagcctccttcgagtacctctacgaacaggggaagtttgagtttgtcaatgac
gttgcatcactttcggacctacatagtgaagctgagatacattacttcaagaatgagagt
ctaggcatggccgtgctgcacctgtcccatcttgccctgcagcgtggtgtccccctggaa
gaggtggtgaggaagaccagcttcaaagactgcatccctcgctccttcagccgacagatc
cagcagaacaattccctgactaaattccgcctgaggaacgtcttccagaagtttatgcga
cgtttccatctgcagacagtgggtccggggcggcttagtgaacgggacatcatgttcaaa
tacttggctacgctggaacagctggccccacgctttggcactgagcactttcttgctctg
accttggcactggccacagaggctgaaagggatctgtgctatgtcaatagcagtgagcaa
gggcctactgttccgccaggagccactctctccctcgctgaccgggctcctagccatgag
gttcgagtgacgggtacaagtggtatccattggcggcttcttcaggtggaggaccctgac
ctggatgtcaaccatcctcgaggctcctttcgtaagaagtccaaggcccgggaggcagag
agccggaagccaagccagctgcccactgagaggaaagagagcccctggatgtatttttgt
gacttccaagatatcactcatgttgtggtcaaggagaataacgtcagcatccaccgtcag
gacaacaagtgcctggaactgactctcctgtcacctatggtggcactctccttggtatcc
ctggtggatggctacttcaggctgacagcagactccagccactacctgtgccgtgaggtg
gcccccccgaggctggtgatgagcgttcaaaatggcatccatgggcccctgcaggagcct
tatgtactatccaaactgaagcgagaggaggtagaagacggtctctaccttatccgttgg
agttcctttgacttccaccgcctcatcctgactgtggctcggaaggaccagacatctgga
gcacaaggtctccgttacaagcagttccgcattgaagagcggggcctgaccttccagctg
gaaggctgggatcaagccttttccagtgtgcgtgagctcactgcggccctgcaaggctgc
acgctgcgatccagctctggctctggtcctggttccagcctagagagcttcacactcagc
aaatgctgcctgcctcgagcaggagaaatttccaacctgatcatcacccgacagcgtcct
aaggagggccctaaaccactcaacttgtcccagcttagcttccaccagatccgtaaggaa
gagatcacccagctggctcacctgggccagggcacccggaccaacatttatgagggactc
ctgcgtgtggggggtggaatgggagctgaggatgaggaagaagagaacatcccctcagaa
cccaacaacaaccatcgggagcttcgagtagtgctgaaggtgctggacccgagtcatcgt
gacattgctctggcatttttcgagacagccagcctaatgagccaggtctcccacattcac
ttggccttcgtccatggtgtttgtgtccggggctctgagaacatcatggtggcagaacac
gtagaacatgggccactggatgtatgtctacgccgggagaagggccatgtgcctgtggcc
tggaagattactgtggcccagcagcttgccagcgctctcagctacctagaggataagaac
ctggttcatggtaatgtctgtggcaagaacatcctgctggcaaggcgtggccttggagat
ggcactcagcccttcatcaagctcagtgatcctggcgtcagtgtcactgccctctccagg
gaggagagggcagagcgcattccctggattgcccccgagtgtgtacccagtgggactggc
ctcagcacagctgccgacaagtggagctttggaacaacactattagaaatctgctttgat
ggggaagcacctctacagggtcgtaccccttctgagaaggagcgcttttatgagaagaaa
caccggcttcctgagccctcatgtaaggagctggccaccctcattagtcagtgcctcacc
catgaggccaaccagcgaccctcctttcgaacaatcctccgtgatctcacccagttgcag
ccccagaatctcgctgacattaccaccgtaagcccagagttcccagcctcagaccctact
gtgtttcagaaacgctacctaaagaagatccgagacctgggagagggccactttggcaag
gtgagcctctactgctatgacccaactaatgatgggacaggtgagatggtggctgtgaaa
tctctcaaggctggctgcagctcccaactcctgagcagctggcaacgggaaattgagatc
cttcggacactttaccatgagcacatcgtcaagtataagggctgctgcagtgaccaaggg
gagaagatggtccagctgatcatggagtatgtgccactaggcagcttgcgggactacctc
cccaaacacagcttggggctggcccagattctgctatttgctcagcagatctgtgagggc
atggcctacctccattcccaacactacatccaccgagacctggcagcccggaatgtcctt
ttggagaatgacaacactgtcaagattggagactttggcctggccaaggctgtgccagag
ggccatgattactactgtgtccaggaggatggagacagccctgtcttctggtatgccatg
gaatgtctcaaggaatgtaagttctactatgcctcagatgtctggtcctttggggtcacc
ctctatgagctactgacccgctgtgactgcaatcaaaccccccccttgaaattcatcgaa
atgattggggttacccagggccagatgacggtgctgaggctcattgacctgctagagaga
gggcagagactgccttgtcccaaggattgtcccagtgagatctatcttctcatgaagaat
tgctgggaatatgaagcctcctttcgcccaaccttccagaaccttgttcccctcctcagg
acattccatgagaagtacagaaatcaagcaccgtctgtgtttagtgtatgctga
DBGET
integrated database retrieval system
