Phascolarctos cinereus (koala): 110214813
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Entry
110214813 CDS
T05867
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00230
Purine metabolism
pcw00670
One carbon pool by folate
pcw01100
Metabolic pathways
pcw01523
Antifolate resistance
Module
pcw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110214813 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
110214813 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110214813 (GART)
Enzymes [BR:
pcw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
110214813 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
110214813 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
110214813 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
CPSase_L_D2
ATP-grasp
ATP-grasp_3
ATP-grasp_4
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_5
Sacchrp_dh_NADP
SNF5
Motif
Other DBs
NCBI-GeneID:
110214813
NCBI-ProteinID:
XP_020851569
UniProt:
A0A6P5L7K0
LinkDB
All DBs
Position
Unknown
AA seq
1011 aa
AA seq
DB search
MAVRVLVIGSGGREHTLAWKLAQSRHVSQVIVAPGNAGTANSGKISNSAVSVSHHTALAQ
FCKDQKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAKAAQLESSKKFAKDFMDRHGIP
TAKWKAFTNPEEACNFVMSADFPALVIKASGLAAGKGVIVASNKEEACKAIQDIMQDKAF
GAAGDTVVIEEVLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDHGPNTGGMGAYCPTP
QVPKDLLLKIKNTILQRAVDGMQQEGVPYVGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSVLDGQLSNSLPVWHEDSAAVTVVMASKDYPANYTKGMEITGIPEA
KALGLEVFQAGTSLREDKVVTNGGRVLTVTAVQKDLISALEEANKGITVIKFEGAVYRKD
IGYRAISFLKQSRGLTYKESGVDIAAGNELVKKIKPLAKATSRPGCNVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDVSTAETVVAGIAKACEKAGCALLGGETAEMPGVYPPGEYDLAGFAVGAMERDQKLP
QLDRITEGDVIIGIASSGVHSNGFSLVRKIVENSSFQLSSLAPDGCGNQTLGELLLNPTK
IYSRTLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKFGVDLDARCWKIPRIFSWLQHEG
CLSEEEMAKTFNCGIGAVMVVQKDLAEQVLKDVHQQEEEAWIIGNVVTCPIGYSRVKVNH
LIETMQINGSFSLVNESLKGCLGIQPKRVQVAVLISGTGTNLQALIDSTRESTSYAQIVV
VISNKAGVAGLQKAENAGIPTKVIDHKLYKSRSEFDSEIDSVLEEFSIDLVCLAGFMRIL
SGPFVQKWNGKILNIHPSLLPSFKGSNAHEQVLEAGVRITGCTVHFVAEQVDSGQIIVQE
AVPVMRGDTIATLSERVKIAEHKAFPAALQMVASGAVKLGKNGKICWNDEE
NT seq
3036 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgcgagtgcttgtaattggcagtgggggaagggaacacacactagcttggaaa
cttgctcagtctcggcatgtcagccaggtgatagttgctccaggaaatgcaggaacagcc
aacagtgggaagatttcaaattcagctgtgtcagtcagtcatcatactgccctcgctcag
ttctgcaaagatcagaaaattgaacttgtagttgttggaccagaggctcctcttgctgct
ggaattgttggggatctaacatctgcaggagtgaggtgttttggtcccacagcaaaagca
gctcagttagagtccagcaaaaaatttgccaaggattttatggaccgacatggaatccca
actgcaaagtggaaggctttcaccaaccctgaagaagcctgcaactttgttatgagtgca
gattttcctgctttggttataaaggccagtggtctagctgctggaaaaggagtaattgtg
gctagtaacaaagaagaggcctgcaaagcaattcaagatataatgcaggataaagctttt
ggagcagctggtgatactgttgtaattgaagaagttcttgaaggagaagaggtgtcttgt
ttatgttttactgacggtaagactgtggccccaatgccaccagcacaggaccataagcga
ttactggatggagaccatggcccaaatacgggaggaatgggagcttattgtccaacacct
caggttcctaaagatctgttattaaaaattaaaaataccattcttcagagagcagtagat
ggcatgcagcaggaaggtgttccatatgtagggatattgtatgctggtataatgcttacc
aaggatggcccaaaagttctggagtttaattgcagatttggggatccagaatgccaggta
attcttccacttcttaaaagtgatttatatgaagtaattcaatcagttttagatggtcag
ctttctaattctctgccagtctggcatgaagatagtgctgctgtaactgttgtcatggcg
agtaaagactatcccgcaaattacaccaaaggcatggagataacaggaattcctgaggct
aaagctttaggcctggaggtgttccaagcaggcacatccctgagagaggataaagtagta
actaatggtggtagagttcttacagtaacagccgtgcagaaagatctgatatcagctctt
gaagaagccaataaaggaataactgttataaaatttgaaggagcagtttatagaaaagac
attggctatcgagctatctctttcctaaaacagtccagaggcctgacttacaaggaaagt
ggggtggatattgcagctggcaatgaactggttaagaaaattaagcctttagctaaagcc
acctccagaccgggatgtaatgtagaccttggaggatttgctggtctctttgacttaaaa
gcagctggttttaaagatccccttctggcatctggaacagatggagttggaaccaaatta
aagattgcccaacagtgcaataaacatgataccattggtcaagatttggttgcaatgtgt
gtcaatgatattttggctcaaggagcagagcctctatttttccttgattatttttcctgt
ggaaaacttgatgtcagcacagctgaaactgtcgttgcgggtatagcaaaagcatgtgaa
aaagcaggatgcgctcttttgggaggtgagacagctgaaatgcctggtgtgtatccccct
ggagaatatgaccttgcaggttttgctgttggtgccatggagcgagatcaaaagctccct
caactggacagaatcactgagggggatgttatcattggaatagcctcttctggagttcat
agtaatggattcagccttgtaaggaagattgtagaaaattcttccttccagttatcctct
ttagcacctgatggatgtggtaatcaaactctaggggaattgttgttaaatccgaccaaa
atctatagccgaacattgttacctgttcttcgttcagggcatgttaaggcctttgcccat
attactggaggtggactacttgaaaacatccctagagttcttccagagaaattcggggta
gatttggatgctcgatgctggaagatccctagaatattctcatggcttcagcatgaggga
tgcctctcagaagaggaaatggctaagacatttaattgtggaattggggctgtcatggtg
gtacagaaagatctggctgagcaagttctgaaggatgtacaccagcaagaggaggaagcc
tggataatcgggaatgtagttacttgtcctataggttattcccgtgtgaaagtcaatcat
ctgattgaaacaatgcaaataaatggatcgttctcattagtgaatgaatctttaaagggt
tgccttggtatccaaccaaagagggtacaagtggctgtcttaatatctggaactggcacg
aatctccaggccctaatagatagcactcgggaatcaaccagctacgcacaaattgttgtt
gttatctctaacaaagctggagtggcagggctacagaaagcagaaaatgctggtattcct
actaaggtaattgatcataaattatataaaagtcgttcagaatttgacagtgaaattgac
agtgtccttgaagagttctccattgacctagtctgtcttgcaggattcatgagaattttg
tctggtccttttgtccaaaaatggaatggtaaaatactcaacatacacccatcattgctc
ccttcttttaagggttcgaatgcccatgagcaggttcttgaagctggagtgagaatcact
ggatgtacagtacattttgtggctgaacaagtggattctggacaaatcattgttcaagag
gctgtcccagtaatgagaggtgacactattgcaactttatcagaaagagtaaaaatagca
gaacataaagcatttcctgctgctttacagatggtggctagtggtgcagtaaaacttgga
aaaaatggaaaaatttgttggaatgatgaggaataa
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