KEGG   Phascolarctos cinereus (koala): 110215167
Entry
110215167         CDS       T05867                                 
Symbol
MAPK1
Name
(RefSeq) LOW QUALITY PROTEIN: mitogen-activated protein kinase 1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw01521  EGFR tyrosine kinase inhibitor resistance
pcw01522  Endocrine resistance
pcw01524  Platinum drug resistance
pcw04010  MAPK signaling pathway
pcw04012  ErbB signaling pathway
pcw04014  Ras signaling pathway
pcw04015  Rap1 signaling pathway
pcw04022  cGMP-PKG signaling pathway
pcw04024  cAMP signaling pathway
pcw04062  Chemokine signaling pathway
pcw04066  HIF-1 signaling pathway
pcw04068  FoxO signaling pathway
pcw04071  Sphingolipid signaling pathway
pcw04072  Phospholipase D signaling pathway
pcw04114  Oocyte meiosis
pcw04140  Autophagy - animal
pcw04148  Efferocytosis
pcw04150  mTOR signaling pathway
pcw04151  PI3K-Akt signaling pathway
pcw04210  Apoptosis
pcw04218  Cellular senescence
pcw04261  Adrenergic signaling in cardiomyocytes
pcw04270  Vascular smooth muscle contraction
pcw04350  TGF-beta signaling pathway
pcw04360  Axon guidance
pcw04370  VEGF signaling pathway
pcw04371  Apelin signaling pathway
pcw04380  Osteoclast differentiation
pcw04510  Focal adhesion
pcw04520  Adherens junction
pcw04540  Gap junction
pcw04550  Signaling pathways regulating pluripotency of stem cells
pcw04611  Platelet activation
pcw04613  Neutrophil extracellular trap formation
pcw04620  Toll-like receptor signaling pathway
pcw04621  NOD-like receptor signaling pathway
pcw04625  C-type lectin receptor signaling pathway
pcw04650  Natural killer cell mediated cytotoxicity
pcw04657  IL-17 signaling pathway
pcw04658  Th1 and Th2 cell differentiation
pcw04659  Th17 cell differentiation
pcw04660  T cell receptor signaling pathway
pcw04662  B cell receptor signaling pathway
pcw04664  Fc epsilon RI signaling pathway
pcw04666  Fc gamma R-mediated phagocytosis
pcw04668  TNF signaling pathway
pcw04713  Circadian entrainment
pcw04720  Long-term potentiation
pcw04722  Neurotrophin signaling pathway
pcw04723  Retrograde endocannabinoid signaling
pcw04724  Glutamatergic synapse
pcw04725  Cholinergic synapse
pcw04726  Serotonergic synapse
pcw04730  Long-term depression
pcw04810  Regulation of actin cytoskeleton
pcw04910  Insulin signaling pathway
pcw04912  GnRH signaling pathway
pcw04914  Progesterone-mediated oocyte maturation
pcw04915  Estrogen signaling pathway
pcw04916  Melanogenesis
pcw04917  Prolactin signaling pathway
pcw04919  Thyroid hormone signaling pathway
pcw04921  Oxytocin signaling pathway
pcw04926  Relaxin signaling pathway
pcw04928  Parathyroid hormone synthesis, secretion and action
pcw04929  GnRH secretion
pcw04930  Type II diabetes mellitus
pcw04933  AGE-RAGE signaling pathway in diabetic complications
pcw04934  Cushing syndrome
pcw04935  Growth hormone synthesis, secretion and action
pcw04960  Aldosterone-regulated sodium reabsorption
pcw05010  Alzheimer disease
pcw05020  Prion disease
pcw05022  Pathways of neurodegeneration - multiple diseases
pcw05034  Alcoholism
pcw05132  Salmonella infection
pcw05133  Pertussis
pcw05135  Yersinia infection
pcw05140  Leishmaniasis
pcw05142  Chagas disease
pcw05145  Toxoplasmosis
pcw05152  Tuberculosis
pcw05160  Hepatitis C
pcw05161  Hepatitis B
pcw05163  Human cytomegalovirus infection
pcw05164  Influenza A
pcw05165  Human papillomavirus infection
pcw05166  Human T-cell leukemia virus 1 infection
pcw05167  Kaposi sarcoma-associated herpesvirus infection
pcw05170  Human immunodeficiency virus 1 infection
pcw05171  Coronavirus disease - COVID-19
pcw05200  Pathways in cancer
pcw05203  Viral carcinogenesis
pcw05205  Proteoglycans in cancer
pcw05206  MicroRNAs in cancer
pcw05207  Chemical carcinogenesis - receptor activation
pcw05208  Chemical carcinogenesis - reactive oxygen species
pcw05210  Colorectal cancer
pcw05211  Renal cell carcinoma
pcw05212  Pancreatic cancer
pcw05213  Endometrial cancer
pcw05214  Glioma
pcw05215  Prostate cancer
pcw05216  Thyroid cancer
pcw05218  Melanoma
pcw05219  Bladder cancer
pcw05220  Chronic myeloid leukemia
pcw05221  Acute myeloid leukemia
pcw05223  Non-small cell lung cancer
pcw05224  Breast cancer
pcw05225  Hepatocellular carcinoma
pcw05226  Gastric cancer
pcw05230  Central carbon metabolism in cancer
pcw05231  Choline metabolism in cancer
pcw05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcw05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    110215167 (MAPK1)
   04015 Rap1 signaling pathway
    110215167 (MAPK1)
   04350 TGF-beta signaling pathway
    110215167 (MAPK1)
   04668 TNF signaling pathway
    110215167 (MAPK1)
   04066 HIF-1 signaling pathway
    110215167 (MAPK1)
   04068 FoxO signaling pathway
    110215167 (MAPK1)
   04072 Phospholipase D signaling pathway
    110215167 (MAPK1)
   04071 Sphingolipid signaling pathway
    110215167 (MAPK1)
   04024 cAMP signaling pathway
    110215167 (MAPK1)
   04022 cGMP-PKG signaling pathway
    110215167 (MAPK1)
   04151 PI3K-Akt signaling pathway
    110215167 (MAPK1)
   04150 mTOR signaling pathway
    110215167 (MAPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110215167 (MAPK1)
   04148 Efferocytosis
    110215167 (MAPK1)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    110215167 (MAPK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110215167 (MAPK1)
   04613 Neutrophil extracellular trap formation
    110215167 (MAPK1)
   04620 Toll-like receptor signaling pathway
    110215167 (MAPK1)
   04650 Natural killer cell mediated cytotoxicity
    110215167 (MAPK1)
   04660 T cell receptor signaling pathway
    110215167 (MAPK1)
   04658 Th1 and Th2 cell differentiation
    110215167 (MAPK1)
   04659 Th17 cell differentiation
    110215167 (MAPK1)
   04657 IL-17 signaling pathway
    110215167 (MAPK1)
   04662 B cell receptor signaling pathway
    110215167 (MAPK1)
   04664 Fc epsilon RI signaling pathway
    110215167 (MAPK1)
   04666 Fc gamma R-mediated phagocytosis
    110215167 (MAPK1)
   04062 Chemokine signaling pathway
    110215167 (MAPK1)
  09152 Endocrine system
   04929 GnRH secretion
    110215167 (MAPK1)
   04915 Estrogen signaling pathway
    110215167 (MAPK1)
   04917 Prolactin signaling pathway
    110215167 (MAPK1)
   04921 Oxytocin signaling pathway
    110215167 (MAPK1)
   04926 Relaxin signaling pathway
    110215167 (MAPK1)
   04935 Growth hormone synthesis, secretion and action
    110215167 (MAPK1)
   04919 Thyroid hormone signaling pathway
    110215167 (MAPK1)
   04928 Parathyroid hormone synthesis, secretion and action
    110215167 (MAPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    110215167 (MAPK1)
  09156 Nervous system
   04724 Glutamatergic synapse
    110215167 (MAPK1)
   04725 Cholinergic synapse
    110215167 (MAPK1)
   04726 Serotonergic synapse
    110215167 (MAPK1)
   04720 Long-term potentiation
    110215167 (MAPK1)
   04730 Long-term depression
    110215167 (MAPK1)
   04723 Retrograde endocannabinoid signaling
    110215167 (MAPK1)
   04722 Neurotrophin signaling pathway
    110215167 (MAPK1)
  09158 Development and regeneration
   04360 Axon guidance
    110215167 (MAPK1)
   04380 Osteoclast differentiation
    110215167 (MAPK1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    110215167 (MAPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110215167 (MAPK1)
   05206 MicroRNAs in cancer
    110215167 (MAPK1)
   05205 Proteoglycans in cancer
    110215167 (MAPK1)
   05207 Chemical carcinogenesis - receptor activation
    110215167 (MAPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    110215167 (MAPK1)
   05203 Viral carcinogenesis
    110215167 (MAPK1)
   05230 Central carbon metabolism in cancer
    110215167 (MAPK1)
   05231 Choline metabolism in cancer
    110215167 (MAPK1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110215167 (MAPK1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110215167 (MAPK1)
   05212 Pancreatic cancer
    110215167 (MAPK1)
   05225 Hepatocellular carcinoma
    110215167 (MAPK1)
   05226 Gastric cancer
    110215167 (MAPK1)
   05214 Glioma
    110215167 (MAPK1)
   05216 Thyroid cancer
    110215167 (MAPK1)
   05221 Acute myeloid leukemia
    110215167 (MAPK1)
   05220 Chronic myeloid leukemia
    110215167 (MAPK1)
   05218 Melanoma
    110215167 (MAPK1)
   05211 Renal cell carcinoma
    110215167 (MAPK1)
   05219 Bladder cancer
    110215167 (MAPK1)
   05215 Prostate cancer
    110215167 (MAPK1)
   05213 Endometrial cancer
    110215167 (MAPK1)
   05224 Breast cancer
    110215167 (MAPK1)
   05223 Non-small cell lung cancer
    110215167 (MAPK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110215167 (MAPK1)
   05170 Human immunodeficiency virus 1 infection
    110215167 (MAPK1)
   05161 Hepatitis B
    110215167 (MAPK1)
   05160 Hepatitis C
    110215167 (MAPK1)
   05171 Coronavirus disease - COVID-19
    110215167 (MAPK1)
   05164 Influenza A
    110215167 (MAPK1)
   05163 Human cytomegalovirus infection
    110215167 (MAPK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110215167 (MAPK1)
   05165 Human papillomavirus infection
    110215167 (MAPK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110215167 (MAPK1)
   05133 Pertussis
    110215167 (MAPK1)
   05152 Tuberculosis
    110215167 (MAPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110215167 (MAPK1)
   05140 Leishmaniasis
    110215167 (MAPK1)
   05142 Chagas disease
    110215167 (MAPK1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110215167 (MAPK1)
   05020 Prion disease
    110215167 (MAPK1)
   05022 Pathways of neurodegeneration - multiple diseases
    110215167 (MAPK1)
  09165 Substance dependence
   05034 Alcoholism
    110215167 (MAPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110215167 (MAPK1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    110215167 (MAPK1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110215167 (MAPK1)
   04934 Cushing syndrome
    110215167 (MAPK1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110215167 (MAPK1)
   01524 Platinum drug resistance
    110215167 (MAPK1)
   01522 Endocrine resistance
    110215167 (MAPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcw01001]
    110215167 (MAPK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pcw03036]
    110215167 (MAPK1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pcw04147]
    110215167 (MAPK1)
Enzymes [BR:pcw01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     110215167 (MAPK1)
Protein kinases [BR:pcw01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   110215167 (MAPK1)
Chromosome and associated proteins [BR:pcw03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     110215167 (MAPK1)
Exosome [BR:pcw04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   110215167 (MAPK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH STATB_N Haspin_kinase FTA2 Kinase-like Kdo
Other DBs
NCBI-GeneID: 110215167
NCBI-ProteinID: XP_020852066
UniProt: A0A6P5L8Z4
LinkDB
Position
Unknown
AA seq 362 aa
MAAAAGGGGGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISP
FEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPAIEQMKDVYIVQDLMETDLYKLLKT
QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDH
DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLN
HILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNP
HKRIEVEQALAHPYLEQYYDPSDEPVAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY
RS
NT seq 1089 nt   +upstreamnt  +downstreamnt
atggcggcggcggcgggaggcggcggcggcgcggggcccgagatggtccgcgggcaggtg
ttcgacgtgggcccgcgttacaccaacctctcctacatcggcgagggcgcctacggcatg
gtgtgctctgcatacgacaacgtcaacaaggtccgagtggccatcaagaaaataagcccc
tttgagcaccagacctactgccagcggacactgcgtgagatcaagatccttctgcgcttc
cgccatgagaacatcattggcatcaatgacatcatccgggccccggccatcgagcagatg
aaggatgtatacatcgtccaggacctcatggagacagacctttacaagctcctaaagaca
cagcacctcagcaatgaccacatctgctacttcctttaccagatcctgcggggtttgaaa
tacatccactcagccaacgttctgcaccgcgacctcaagccttccaacctgctgctcaac
accacctgcgatctcaagatctgtgacttcggcctggctcgtgttgcagatccagaccac
gaccacacaggcttcctgacagaatacgtggccacacgctggtaccgagcacctgaaatc
atgctgaattccaagggttacaccaagtccattgacatctggtccgtgggctgcatcctg
gcagagatgctctccaacaggcccattttccctggaaagcattaccttgatcagctgaac
cacatccttggtattcttggatccccgtcccaagaagacttgaactgcataataaaccta
aaagccaggaactacttgctgtctcttcctcacaaaaacaaggtgccatggaatcggctc
ttccccaacgctgaccccaaagctctggatctgttggataagatgttgacatttaacccc
cacaagaggattgaggtagagcaggcactggcccatccctacctggagcagtattatgac
ccaagtgatgagcctgtagccgaagccccgttcaagtttgacatggaattggatgacctg
cccaaggagaagctgaaagaactgatttttgaagagaccgctcgattccaacccggatac
cgatcttaa

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