Phascolarctos cinereus (koala): 110215845 Help Entry 110215845         CDS       T05867                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism pcw  Phascolarctos cinereus (koala) Pathway pcw01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:pcw00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     110215845 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:pcw03032]     110215845 (TOP2A)    03036 Chromosome and associated proteins [BR:pcw03036]     110215845 (TOP2A) Enzymes [BR:pcw01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      110215845 (TOP2A) DNA replication proteins [BR:pcw03032]  Eukaryotic type   DNA Topoisomerases    110215845 (TOP2A) Chromosome and associated proteins [BR:pcw03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     110215845 (TOP2A)   Centrosome formation proteins    Centriole proteins     110215845 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c ComGE Motif Other DBs NCBI-GeneID:  110215845 NCBI-ProteinID:  XP_020853308 UniProt:  A0A6P5L5C3 LinkDB All DBs Position Unknown AA seq 1558 aa AA seqDB search MEDLSPLQPVNENLQINKIKKNEDTKKRVSVERIYQKKTQLEHILLRPDTYIGSVEVVTQ QMWVYDEEVGLNYRDVTFVPGLYKIFDEILVNAADNKQRDPKMNCIKVTIDSENNTISIW NNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTV ETACKEYKKLFKQTWMDNMGKAGEMILKPYSGEDYTCITFHPDLSKFKMTSLDKDIVALM SRRAYDIAGSTKDVKVFLNGNRLPVKGFRSYVDLYVKDKLDETGNPLKIIHEEVNSRWEV CLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSRLIDVVKKKNKGGVAVKTHQVKNH MWIFVNALIENPTFDSQTKENMTLQAKSFGSKCELSEKFIKAAIGCGIVESILNWVKFKA QVQLNKKCSAVKHNRIKGIPKLDDANDAGSKNSTDCTLILTEGDSAKTLAVSGLGVVGRD KYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDADSLKSLRYGKIMIM TDQDQDGSHIKGLLINFIHHNWPSLLKHRFLEEFITPIVKVSRNKQELSFYSLPEFEEWK SSTENHKKWKVKYYKGLGTSTSKEAKEYFSDMSRHRIQFRYSGPEDDAAISLAFSKKQID DRKEWLTHFMEDRRQRKLLGLPEDYLYGKATKHLTYNDFINKELILFSNSDNERSIPSMV DGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSN NLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPQDDQTLKFLYDDNQRVEPE WYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTI DELAPNQYVISGEVSILNSTTIEISELPVRTWTQVYKEQVLEPMLNGTDKTPPLITDYRE YHTDTTVKFIVKMTEEKLAQAEHAGLHKVFKLQTNLTCNSMVLFDHVGCLKKYDTALDIL KDFFDLRLKYYGLRKEWLTGMLGAESAKLNNQARFILEKIEGKIVIENKPKKELIKVLIQ RGYDSDPIKAWKEAQQKSPGDNEEENEESENEKETEKSDSTTDSGPTFNYLLDMPLWYLT KEKKDELCRQRTAKEQELETLKRKSPSDLWREDLAVFVEELEVVEAKEKRDEQVGVVGKG KAGAKPKAKKGQLAEILPSPCGRRVVPRVTVEMKAEAEKKIRKKIKTESIEESSQDDSIE PETLKQRLNKKIKTEPGTKQKKQTKLPFKPIKKENKKNPWSDSESDMSCNESDFYVPPRE TKLRRTAAANTKYTVDLDSDSDISDSKEEFQDEDEDFIPSDGSSSQVKRAPKATKGQATS KEEEPQKSSSSTEVEDLQPEDTKDMAPASSGSSAYSFLVEPEITDPVPKKSTTVKKTAAK SQSSTSTAGTKKRAAPKTSKKALASKASPDSVSGASEKPVPAKSQKPRKRKPSNSDDSDS DFGKSISTAKAGKKSKKVDDDFQIDSNSSSAPVAPRARPGRAKKPIKYLEESDEDDMF NT seq 4677 nt NT seq  +upstreamnt  +downstreamnt atggaggatctgtcgccgctgcagcccgtaaatgaaaatctacaaattaataaaataaag aaaaatgaggacacaaagaaaagagtgtctgttgagagaatctatcaaaagaaaacccag ttggagcatattttgctccgccctgatacctatattggctcagtggaggttgtgacccag caaatgtgggtttatgatgaagaagttggacttaactacagagatgtaacttttgttcct ggattatacaaaatttttgatgaaattttagtaaatgccgcagacaacaagcaaagggac ccgaaaatgaattgtattaaagtcacaatagattcggaaaacaatacaattagtatctgg aataatgggaaaggtattcctgttgtagagcataaggttgagaaggtctatgtgccagct cttatctttggacaactcttgacttccagcaactatgatgatgatgagaagaaggtcaca ggtggtcgaaatggatatggagccaaattatgcaatatattcagtaccaaatttacagtg gaaactgcctgtaaagaatataagaaactgtttaagcagacctggatggataacatggga aaagcaggtgaaatgattctcaagccctatagtggagaagactatacatgtatcaccttc caccctgatctgtctaaatttaaaatgacaagtctagataaggatattgttgccttgatg tctagaagagcatatgatattgctggttccaccaaagatgtcaaagtctttcttaatgga aataggctgcctgtaaaaggattccgtagctatgtggatttgtatgtgaaggacaaattg gatgaaactggcaacccactgaaaattatccatgaagaagtaaacagcaggtgggaagta tgtttaactatgagtgaaaaaggcttccagcaaattagctttgtcaacagcattgccact tccaagggtggcagacatgttgattatgtagctgatcaaattgtaagtagacttattgat gttgtgaagaaaaagaacaaagggggtgttgctgtaaaaacacatcaggtgaaaaaccac atgtggatttttgtgaatgccttaattgaaaacccgacctttgactcccagactaaggaa aatatgactctgcaggccaagagctttggttcaaaatgtgaattgagtgaaaaattcatc aaagctgcaattggctgtggaattgtagaaagcatactaaattgggtgaagtttaaggcc caagtccagttgaataaaaagtgttcggctgttaaacacaatagaatcaaaggaattcct aaacttgatgatgccaatgatgcaggcagcaagaactctacagattgtacacttatcttg actgagggagactcagccaaaactttagctgtttctggccttggtgtggttgggagagac aagtatggtgttttcccccttcgaggaaaaatactcaacgtacgagaagcctctcataaa caaatcatggaaaatgctgaaattaacaatatcattaagattgtgggtcttcaatataag aaaaactatgaagatgcagattcattgaagagtctccgctacggaaaaatcatgattatg acagatcaggatcaagatggttctcacatcaaaggcttgttgattaatttcatccatcac aattggccctctcttctgaaacatcgttttctggaggaatttatcactcctattgtaaag gtttcaagaaataagcaggaattatcattttatagccttcctgaatttgaagaatggaaa agttctactgaaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagt acatcaaaagaggctaaagaatacttttcagatatgtccagacatcgaatccaattcaga tattctggccctgaagatgatgctgcaatcagcctagcctttagcaaaaagcaaattgat gatcgaaaagagtggctaactcatttcatggaagatagaagacagaggaagttacttggc ctccctgaggattacttatatgggaaagctactaagcatctaacatataatgacttcata aataaagaactaatcttattctcaaactctgataatgagaggtccattccatcaatggtg gatggtttgaaaccaggtcagagaaaagtcctgttcacatgtttcaaaagaaatgacaag cgagaagtgaaggttgcccaattagctggttcagtagctgagatgtcctcttatcatcat ggtgagatgtcactaatgatgaccattattaatttggctcaaaattttgtgggcagcaac aatctcaacctcttgcagcccattggtcagtttggtaccaggctgcatgggggcaaggac tctgctagccctcgatacatctttacaatgctcagtccattggctcggttgcttttccca ccgcaagatgatcagactttgaagttcttatatgatgacaaccaacgtgtagagccagaa tggtacattcctattattcccatggtattgataaatggtgcagaagggattggcactggg tggtcctgtaagatccccaactttgatgtccgagaagttgtgaataatatcagacgtctg atggatggagaagaacctttaccaatgctgcctagttacaaaaatttcaaaggtacaatt gatgagctggctccaaatcaatacgttatcagtggtgaagtgtcaattctaaattcaaca accattgaaatctctgagcttccagtcagaacttggacccaggtatataaagagcaggtt ctggagcccatgttgaatggcactgacaagacaccacctctcataacagactatagggag taccacactgataccacagtgaagttcatagtgaagatgactgaagaaaaattggcccaa gcagagcatgcaggattgcacaaagtcttcaaacttcagactaatctaacatgtaattcc atggtgctttttgatcatgttggctgtctaaagaagtatgatactgctctggatatccta aaagacttctttgatctgaggcttaaatattatggactgagaaaagaatggcttaccgga atgcttggagctgaatctgccaaattgaacaaccaggctcggttcatcctagagaagata gaggggaaaatagtcattgaaaataagccaaagaaagagttaattaaggttctgatccag aggggatatgattcagatcctatcaaggcctggaaggaagctcagcaaaagagtccagga gacaatgaagaggaaaatgaagaaagtgaaaatgaaaaagaaactgaaaaaagtgattct accactgattctggaccaacttttaattaccttcttgatatgcctctctggtatctgacc aaagagaagaaagatgaactctgcaggcagaggactgcaaaagagcaagaattggagacc ttaaaacgaaaaagtccttcggatttatggagagaagaccttgctgtttttgttgaagaa cttgaggttgttgaagccaaggaaaaacgagatgaacaagtgggtgttgttggtaaaggt aaagctggtgcgaaaccaaaggcaaagaaaggtcaactggcagaaattttgccttctcct tgtggcagacgagtagtccctcgagtaactgtagaaatgaaagcagaagcagaaaagaaa atcagaaagaaaattaagactgaaagtatcgaagaaagttctcaagatgacagtatagaa ccagaaactctgaaacaaagactgaataaaaagattaagacagaaccaggtaccaaacaa aagaagcagaccaaattgccattcaaaccaatcaaaaaagaaaataagaaaaatccttgg tccgattcagaatctgatatgagttgtaacgaaagtgacttttatgtcccccctagagaa actaaattacgcaggaccgcagcagcaaataccaaatacacagttgatttagattcagac agcgatatttcggattctaaagaggaatttcaagatgaagatgaggattttatcccatca gatggaagttcatctcaggttaaaagggcgccaaaagcaactaaaggacaagctactagc aaagaagaggagccacagaaaagttcttcatcaactgaagttgaggacctgcaacctgag gatactaaggacatggctccagcttcttcaggctcttctgcttacagttttctagttgaa cctgagattacagatccagttcccaaaaagagcaccacagtgaaaaagactgcagcaaag agtcagtcttccacttctactgccggaacaaagaaaagggcagcaccgaaaacaagcaaa aaggcccttgcctccaaagcgtctccagactccgtctctggagcctctgaaaagcctgtg ccagccaaaagccagaaacctcgcaaaaggaagccttccaactctgacgactcggattcc gattttggaaaaagcatatcaacagccaaggcagggaagaaatccaagaaagtggatgat gacttccaaattgactcaaattcaagctcagctcctgtggcaccccgggcaagacctgga cgagcaaagaagcctattaagtacctggaagaatcagatgaagatgatatgttttaa

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