KEGG   Phascolarctos cinereus (koala): 110220599
Entry
110220599         CDS       T05867                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw04137  Mitophagy - animal
pcw04140  Autophagy - animal
pcw04141  Protein processing in endoplasmic reticulum
pcw04156  Integrated stress response (ISR) signaling pathway
pcw04210  Apoptosis
pcw04932  Non-alcoholic fatty liver disease
pcw05010  Alzheimer disease
pcw05012  Parkinson disease
pcw05014  Amyotrophic lateral sclerosis
pcw05020  Prion disease
pcw05022  Pathways of neurodegeneration - multiple diseases
pcw05160  Hepatitis C
pcw05162  Measles
pcw05164  Influenza A
pcw05168  Herpes simplex virus 1 infection
pcw05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    110220599 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110220599 (EIF2S1)
   04137 Mitophagy - animal
    110220599 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    110220599 (EIF2S1)
   04156 Integrated stress response (ISR) signaling pathway
    110220599 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    110220599 (EIF2S1)
   05164 Influenza A
    110220599 (EIF2S1)
   05162 Measles
    110220599 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    110220599 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110220599 (EIF2S1)
   05012 Parkinson disease
    110220599 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    110220599 (EIF2S1)
   05020 Prion disease
    110220599 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    110220599 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110220599 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    110220599 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:pcw03012]
    110220599 (EIF2S1)
   04131 Membrane trafficking [BR:pcw04131]
    110220599 (EIF2S1)
Translation factors [BR:pcw03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    110220599 (EIF2S1)
Membrane trafficking [BR:pcw04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    110220599 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 110220599
NCBI-ProteinID: XP_020860315
UniProt: A0A6P5LPD4
LinkDB
Position
Unknown
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YSKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDGLDLNERERRVLIDNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccaggactaagttgtagattctaccagcacaaatttcctgaagtggaagatgtagta
atggtgaatgtacggtccattgctgaaatgggagcttatgtcagcctattggaatacaac
aatattgagggcatgattcttcttagtgagctctctagaaggcgtatccgctccattaac
aaactcatcagaattggcagaaatgaatgtgtggttgtcattagagtggacaaagaaaaa
ggatatatcgatttgtcaaaaagaagagtttctccagaagaagcaatcaaatgtgaagac
aaattcaccaaatccaaaactgtttatagcatccttcgccatgttgctgaagtgttagag
tacagtaaggatgagcagctggagagcctattccagagaactgcctgggtctttgatgac
aagtacaagagaccaggatatggtgcctatgatgcatttaaacatgcagtctcagaccct
tcgatcctggatggactggatttgaatgaacgtgaaagacgagtgctgattgataatata
aataggcgcttgacaccacaagctgtcaaaatccgagctgatatcgaagtggcttgttat
ggttatgagggtattgatgctgtaaaagaagctctgagagcaggtttgaattgttccaca
gaaaacatgcccatcaagattaacctgatagcacctcctcggtatgtgatgaccactaca
accctagagagaacagaaggtctgtctgtcctcaatcaggctatggctgtcatcaaagaa
aagattgaggagaaaagaggtgtcttcaatgttcaaatggagcccaaagtggttacggac
acagatgaaactgagcttgcgagacagctggagaggcttgagagggaaaatgctgaggtg
gacggagatgatgatgctgaagaaatggaagccaaagctgaagattaa

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