Phascolarctos cinereus (koala): 110223606 Help Entry 110223606         CDS       T05867                                  Symbol SPG11 Name (RefSeq) spatacsin isoform X1   KO K19026   spatacsin Organism pcw  Phascolarctos cinereus (koala) Pathway pcw05014   Amyotrophic lateral sclerosis pcw05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:pcw00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     110223606 (SPG11)    05022 Pathways of neurodegeneration - multiple diseases     110223606 (SPG11)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:pcw03400]     110223606 (SPG11) DNA repair and recombination proteins [BR:pcw03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     Other HR factors      110223606 (SPG11) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spatacsin_C Motif Other DBs NCBI-GeneID:  110223606 NCBI-ProteinID:  XP_020864875 UniProt:  A0A6P5M2N0 LinkDB All DBs Position Unknown AA seq 2453 aa AA seqDB search MAAQEGAGSGCDGGAPSTGAMERVLPMLLVPVPAEARARLGPRARLHREQEALGSLTASG SLQLLSLAPGGRGGNGCSLAGPFRHFVWENSQTSDPPTDKPKLLTLSDNHELCVHEFKMK DGKCDVTTLWSCSGEMLKKLIEDKNIRISSLSRLRILSFQNNSSVLLINRCIVLHIVFPE RDAEVKTLSCFTLALPAQALERITDSQLCRGFLFVLDSSGWIYIFDAVDGTYLARVDLTL HQDQADTCEEEQQQPADTPSFTALKVSWELDVVVVISCSSTAVAVDLNVYFRQHPEHILC ERKLENLPIRGLEGVDEDDPASSVYSMKLTRFSFQVDRSWKTQLSELYNSTMKPRLEVVN YVPWFQSLLHFDPSESSSHPALEETWTFIPQGLTRVQCSHPWKDPIRSDDLKKLWKVMPI EEQEGTAKLKCVSVTGFTVLFTWLVESTGWTVVLWDLETQNVHRVFLGKKCIPVDSSGSQ QLCLVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNAWGRCSIPIRALEAGLE NRQLDTVDFFLKSKENLFNPSSTSSVPDQPARLPSHMYLKSVKELIQALDLLCSAIREND SETQSKHFSEQLLKLTLSFLNKQIREIFAHTEELDEHLQNGVDILTNYIIELRTFMIKFP RKPADAVNACVGEDVPRISESEMWRKLSPEQVISNAILNNKIPEAQSFFRITNHAAQNLG ELIRIGLDLVFDRLLKNNIREASELLKNMGFNVKDQLHKICFYTAEKNVRDFLVGILKEE NYFSEEEKRIIDYVHEIEKLYSRPFKENTETQPLSFRSWRREDDFSKHRSVLDFLKFNEK DEIFKHDHGIILSWAQWWDCPTRENILLPRRSTEEFKSCSPQVLWRHITARHDWLSIFSW IEELQTPDGCVSLQQAKWPHLTVDIIDQNTCCSSYLRNEILDKLARNGIFLTSELEDFEL LLLRLSRIGGVMQDPLPVQNYASRDGLDFHACFLLYCLEHSLQHLLYVYLDYYNLNPLNC PLLEKKELHETYPWFEFLVRCRQVSSNLADPKLIFHASLANAQILIPSNQASVSSMLLEG HTLLALATTVYASGGLSQVVQKEEGETSLGKVDPQLLKMALTPYPKLRATLFPQYVVRSM LPHDVTLYHLIQSLSPFDPTRLFGWQATNTLAIADSSSDLPHFSSPELVNKYAIMERLNF AYYLHHGRPSFAFGTFLVQELVKSKSPKQLIQQVGNEAYMLALSLFHMPSVAAACVCFLE LLGIDSLKLRIDMKVANIILSYKCRNEEAQYSCIRESLAEKLVKLANGRKAATEELLSLL EEGIWDSIQQQGISRTSSESGRQWSLVVHFCRLHNVRLSTAYLRECSRANDWLQFIVYSQ LHSYPLEEVRSLLRYFSPVLQDHLQLAFENLPSFPNSKAHDRQACDRPLWEAQRRQEGTS TDLFQILLQCPEEPDSWRYLLAEAVRQRAPILSILASCFKNADIVSCLSVWIITSVDDRV AAEATSHIQGSVEDHEWALEDLSLIWRMLVTRKKSRTLTRSFQLFLKDSTLLLMMEMYEL CMLCKNYQAAKVKLLELQKNLETIETADNTAPLAIPVPWLKCQVSLLWKLMLQQCETQYE LRKLLQLFSEIDHLSDGPDVKKLCVLSQILKDTSISINHSIITSYSTENFEQECRSIVER LQTERQFALARKVAELAELPVDSLVIEEITQEMQTLKHIGQWYLKQARIEFWKKCHENFK KNSILKRIASDFFLVQATVTSESSADEKWCNIMERHLLLTLAGHWLAQEDPVPLEKLEEL EKQIWHCRVTKQIHCSDQEVVESRLSRQISTSGDLSFDSLAAEFSFSKLAALNASEYLEI NAFPPREASESRLDKTEAESLNFLIGHLLDDGSVHEASRVCHYFQFYNQDVFLVLHCRAL ASGEASVDDLHPEIQAMLRSAELPEEKEEEKEEEEAGAPIRRFQSTSSLDTQSFVMVTHG DEIAAHLDTLRSRCLHGKSYCRQVLCLYELAKELGCTYQEISAQDSTAVLQAILSSQQPD RCKRAQAFITTQGLKADKVADLVAEEVMQELLAASAGKGQKQASSPAEEGLMFFQLTALC QDRTLVGMKLLDKISSVPPGELSCTTELLILAHQCFTLTCHMEGIIRVLQAARLLTDNHL APNDEYGLVVRLLTGIGRYNEMTYIFDLLHRKHYFEVLMRKKLDPSGTLKTALLDYIKRC RPGDSEKHNMIALCFSMCREIGENHEAAAHIQLKLIESQSWEECIKDGPQLKQLLLKALT LMLDAAESYAKDSCVRQALHCQRLTKLITLQIHFLNTGQNTMLINLNRQNLTDCIMALPR FYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKHQRLLKTSVFEEISKKFKQHQP TETVTKNMKKLLSYCEDVYLHYKLAYEHKFYDVVNKLLKEPQTGCCLNDMLAN NT seq 7362 nt NT seq  +upstreamnt  +downstreamnt atggcggctcaagagggggccggaagtggatgcgacggtggcgctccctcgaccggggct atggagagggtgctgcctatgttgttggtgccggttcccgccgaggccagagcgaggctg gggccccgggcccggctacaccgggagcaagaggcgctgggcagcctcacggcctcaggc agcctccagcttctgtcgctagcaccaggcggccgcggcgggaatggctgcagcctcgcg ggccccttccggcactttgtttgggagaattcccaaaccagtgacccaccaacagacaag cctaaacttctgaccctcagtgataatcatgaattgtgtgtccatgagttcaagatgaag gatggaaaatgtgatgtcaccacattatggagctgcagtggggagatgttaaaaaagcta attgaagacaaaaatattagaatttcttctttatcacgcctgagaattctgtcatttcaa aacaactcatcggtgctgctcatcaacagatgtattgtcctacacattgtatttcctgag agagatgctgaggtcaaaactctcagctgcttcactctggctttacctgcacaggctttg gaaaggataactgattcacagctttgcagaggatttctttttgttttggatagttctggc tggatctacatttttgatgctgtagatggcacatatcttgctcgtgtggatctaaccctt caccaggaccaggctgatacatgtgaggaggagcaacagcagccagctgacacgccttca tttactgccttgaaggtgtcttgggagctggatgtggttgtggttatcagctgctctagt actgcagttgctgttgacttaaatgtctatttcaggcaacatccagaacatatactgtgt gagagaaagctagaaaatcttcccatcagaggacttgaaggagtggatgaagatgaccct gccagctcagtctacagcatgaaactgaccaggttttcattccaggtggatagatcctgg aaaactcagctgtcagaattgtacaactcaacaatgaagcccagattagaagttgtgaat tatgtaccctggttccagagtcttcttcattttgacccctctgaatctagtagccaccct gcactggaagagacttggaccttcattccacaaggcctaactcgtgtccagtgcagccac ccgtggaaggatcctattaggtcagatgatttaaagaagttatggaaggtaatgcccatt gaagaacaagaggggacagcaaagctcaaatgtgtgtctgtgacaggattcactgtactt tttacatggttagtagaaagtacaggctggacagttgtcctgtgggacttggagacacag aatgtgcatcgagttttccttggcaaaaaatgcattcctgtggacagcagtggaagccag caattgtgccttgttctgacagaaaatggactctctctgattttgtttggtttgactcaa gaagaattcttgaataggctaatgatccatggaagtgccagcactgttgatactctctgt catcttaatgcttgggggaggtgctcaatccctatacgtgcattagaggctgggttagag aaccgtcaactggatacagtagacttctttttgaagagcaaggagaatcttttcaatccc tcttccacctcttctgtgcctgaccagcctgccaggcttccatctcacatgtatttgaaa agtgtgaaggaactgatacaagctttggatttactttgttcagctatacgagagaatgat tctgaaactcagagcaaacatttttcagagcagctgctgaagctcacattatctttcctc aacaaacaaatcagggagatctttgctcacactgaagagttagatgaacacctgcagaat ggtgtggatattttaaccaactacattattgaacttcgaaccttcatgataaaatttcct cggaaaccagctgatgctgtaaatgcatgtgttggtgaagatgtccccagaataagtgag agtgaaatgtggagaaaactcagccctgagcaagttatctccaatgccattttaaataac aaaataccagaggctcagagctttttcaggatcaccaaccatgctgctcaaaaccttgga gaactgattcgaataggattagatctagtctttgacaggctgctaaagaacaatatcaga gaagcttccgaactcttaaagaatatgggcttcaatgtaaaggaccagttgcacaaaata tgtttctatacagctgagaaaaatgtacgggactttctggttggcattttgaaagaggaa aattatttttctgaagaagagaagagaattatagactatgtacatgagattgaaaaatta tattcaagacctttcaaagaaaacacagagacccagcctctcagtttcaggagctggaga agggaagatgatttttccaaacacagatctgttttagacttcttgaaattcaatgagaaa gatgaaatttttaagcatgatcatggaattatactaagctgggctcagtggtgggattgt ccaacccgagaaaacatccttcttcccaggagatctacagaagaattcaagtcttgttct cctcaagttctctggagacatatcacagctcgccatgactggttaagcattttctcgtgg atcgaagaattacagaccccagatggttgtgtttcacttcagcaggctaaatggccccat ctgacagtagatattattgaccagaatacgtgctgcagtagctacttgaggaacgaaata ctggataaactggccagaaatggaattttcctaacatctgaactagaagactttgaactc ttgctcctaagactaagccgtattgggggcgtaatgcaagatccacttcctgttcaaaac tatgcatctcgagatggtttggatttccatgcatgctttcttttatactgtttagagcac agtctgcagcatctgctctatgtctaccttgattattacaaccttaatcctttgaattgt ccccttttggagaaaaaagaattgcatgaaacttatccttggttcgaatttttggttcgg tgtcgacaagtttccagtaatctggcagatccgaaactgattttccacgccagtctcgct aatgctcagatactgattcccagtaaccaagccagcgtgagcagtatgctgttggaagga cataccctcttggcacttgctacaacagtgtatgcttctggaggcctcagccaggttgtt cagaaagaagaaggggaaacctctttggggaaggtggatccccagctactaaagatggcc ttaactccttaccccaagctcagagctacgctctttccacagtacgttgtccgtagtatg ctgccccatgatgttaccctgtaccaccttattcagtccttgtctccctttgatcccacc agactgtttggctggcaggccactaatactcttgccattgcagattcctcaagtgatctt cctcatttctctagccctgagcttgtaaacaaatatgctataatggaacgtctgaatttt gcttattatttacatcatggacgaccatcatttgcatttggtacttttcttgttcaggaa ttagtcaagagcaagtctccaaagcaactgatccagcaagtaggaaacgaagcctacatg ttggcactttccctctttcatatgccttcagtagcggctgcttgtgtgtgtttcttggaa ttgcttggtatagacagcctcaagcttagaattgatatgaaagtggccaacatcattttg agctataagtgtagaaatgaagaggctcagtacagctgcatcagagaatccctagctgaa aagctggttaaactggctaatggcagaaaagcagcaactgaagaattgcttagtctttta gaagaaggcatatgggatagtattcaacaacaaggaatatcgaggacctccagcgaatca ggccgccagtggtcattggtggtgcacttctgcaggcttcataacgtgcggctgagcaca gcttacctcagggagtgttctagagccaatgactggctacagttcattgtgtacagccag ctccacagttaccccctggaggaagtcaggtccctcctccgctacttcagcccagtcctg caggaccacttgcagctggcctttgagaacttgccttcatttccaaactccaaagcacac gatagacaggcttgtgacagacccctgtgggaggctcagaggagacaagaggggacatcc actgatttatttcagattctgcttcagtgtcctgaggaaccagattcctggcgttacctt ctggctgaagccgtgagacaacgggctcccatcctgagcatcctggcctcttgtttcaag aatgcagatattgtttcttgtctgagtgtttggatcatcacttctgtggacgatcgtgtt gctgctgaagcaacaagtcacattcagggttctgtagaagaccacgaatgggctctggag gacctttcacttatatggagaatgttggtaacaagaaaaaagagcagaactcttaccaga agcttccagctttttctgaaggattccactttgctgttgatgatggagatgtatgaactg tgtatgctctgcaagaactaccaggcggccaaggtcaaactgctagaactccagaagaat cttgaaaccattgaaacagcagataatacagcccctcttgccattcctgtgccgtggcta aaatgtcaggtcagcttgctttggaagcttatgttgcagcagtgcgaaacccagtatgag ctacgaaaactgttgcagctgttttctgaaatagaccatctttctgacggtccagatgtg aagaagctgtgtgtgctcagccagattttgaaggacacatccatatctattaatcattct atcataaccagttacagcactgagaactttgagcaggaatgcagatccattgtggaaagg ctgcagacagaaagacagtttgccctggctaggaaggtagcagaattagctgaattacct gtggacagcttggttattgaagagataactcaggagatgcagaccctaaaacatattggt cagtggtacctgaaacaagcaagaattgaattctggaaaaaatgtcatgagaattttaag aagaactccattttaaaaagaatagcatctgacttttttttagtccaggccactgtgaca tctgagtcctcagctgacgagaaatggtgcaacattatggaaaggcatttgctgcttacc ctggcaggccattggcttgcccaggaggaccctgtgcccttagaaaagctggaagagctg gagaagcagatctggcattgtcgtgtcaccaagcagatccactgtagtgaccaagaggtg gttgaatcaaggctttctcgacagatttcaaccagcggcgacctttcctttgatagctta gccgctgaattttccttctccaaactagctgccctgaatgcctcagaatacttagagatt aatgcctttccccctagagaagcctctgagagtagactggataaaactgaggcagagtca ctaaactttctgattgggcatctgttagatgatggctctgtgcatgaagcaagcagagtt tgccactattttcagttctataatcaagatgttttcttggtgttacactgtagagcatta gcctcaggagaagctagtgtagatgatttgcacccagaaatccaagctatgcttcgaagt gctgagctgccggaagagaaggaggaggagaaggaagaggaagaagctggagctccaatt aggaggtttcagagcacctcaagcctggatacgcagtcttttgtcatggtgacacatggt gatgagattgcagcccatctggacactttgagaagcaggtgccttcatgggaagagctac tgccggcaagtcctttgtctgtatgaacttgccaaggagctgggctgcacttaccaggag atctccgctcaggacagtacggctgtgctccaagccatcctgtcctcacagcagccagac cgctgtaagcgagcgcaggctttcattactacccaaggtctgaaggcagacaaggtggcc gaccttgtggctgaagaggtgatgcaggagctgttggccgcctcagcaggaaaaggacag aagcaagcatccagtccagcagaggagggcctaatgttcttccagctgactgctctgtgc caggatcgaacactggttggcatgaagctgctagacaagatttcctcagttccccctggg gaactgtcctgtaccacggagttactgatcctggcccatcagtgtttcactctgacgtgt cacatggaaggcattatcagggtcttgcaggcggctcggctgctcactgataaccactta gcccccaacgatgagtacggactggtggtacgccttctgacgggcattggaagatacaat gagatgacctacatatttgatttgctgcacagaaaacactactttgaagtgttaatgagg aaaaagctggacccgagtgggaccctaaagacggccctcctggactacatcaagcgctgc cgtccaggagacagtgagaagcacaacatgatcgctctctgcttcagcatgtgccgggag attggggagaaccatgaggcagctgcccacatccagctgaagctgattgaatctcagtcc tgggaggaatgtatcaaggatgggccccagctgaaacagctgctgctaaaagccctgact ctgatgttggatgcagcggagagttatgctaaggattcctgcgttcgtcaggctctgcac tgtcagcggcttacaaagctgataacgctacagattcattttctaaatactggccagaac acgatgctcatcaatcttaacaggcagaatctgacagactgcatcatggctttgcctcgg ttctatcaggcctctattgtagctgaagcctatgactttgttccagattgggctgaaatt ctttatcaacaagtgattctaaaaggtgacttcaattacctggaagaatttaagcatcaa aggttattaaaaaccagtgtatttgaagagatttccaaaaaatttaaacagcaccagcca actgaaacagttacaaagaacatgaaaaagttactgtcatactgtgaagatgtctacctg cattataagctggcatatgagcacaagttctatgatgttgtaaataagcttctcaaggag cctcagaccggatgttgtctgaatgacatgttagcaaattag

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