Plasmodium cynomolgi: PCYB_072640
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Entry
PCYB_072640 CDS
T02490
Name
(RefSeq) gamma-glutamylcysteine synthetase
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pcy
Plasmodium cynomolgi
Pathway
pcy00270
Cysteine and methionine metabolism
pcy00480
Glutathione metabolism
pcy01100
Metabolic pathways
pcy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
pcy00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
PCYB_072640
09106 Metabolism of other amino acids
00480 Glutathione metabolism
PCYB_072640
Enzymes [BR:
pcy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
PCYB_072640
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Gene cluster
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
14692110
NCBI-ProteinID:
XP_004221709
UniProt:
K6V9B5
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Position
7:747639..750797
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AA seq
992 aa
AA seq
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MGFLKIGTPLSWEEVQKVKSLIRLYGILQFVHTYKCNKDRVDENIMFGDEIEYIVIRNDE
NFKESAALLCATDLIDEMMNLESVTYCQYGSHWTPEYSSFTIEGTPSVPFKFDINSSPFV
EDCMRIRRIKLNNVLSAIMGEVRAITLPCFPNALLENSLLMAKRITQETGKRKGDRGKGA
MGSGGDTLETPAIEHVKQKQAEKGQGEMVRQVITEGEYKITLNDSTQTYADEGKSTQFVN
SDVVAQRNDDSLMQEMCGDEVGGADQADQADQADQADQADQAGHSNESNESKQANQASTP
NQPIFINEAKENLLFECDLFKPEQTKNYSNSCLITDMVISPHARYVTLTKNIRKRRGTKI
ISFNEIYKDENTEKLPRWEHSLDKTDRRLFKKIKKKYVLDEHLIWNKSMTNKKRVEPIGL
DFPPSGAEAASPAVVEASENPSAEDALPAPDNLIDEVIKNSLFSNLDDEKDHIYVYDRKF
IQEYSEKCKNPIKNYVYLDAMFFGMSMCCQQVTMSFPTIDDAKYLYDQLAVIAPLFLALT
ASTPYLGGFLTETDTRWRVISNSVDCRTEEELAYISKPRYSGISLYISNELPLRKNYHFY
NDIDVVLDKNVYDKLVKENVDDFLARHVASLFVRDPIVVFEGSYSERDIQSVEERMKGEM
GSEMGNQNPINSVYLSDDFNFLEDYEETVLSSHQHFENFQSTNWNSVRFKPPPILSNHCN
GTSSIGWRVEFRTPDIQITDFENASVVTLIMVLSKFILKEKLNLYIPMSMLEENLFRSGN
RDAIFKEKFYFRRDLTYDTEDNEVEEKTLYDIFFNNHNGIFFLCSKYIEEQFREGLLSHA
AKNKIDEYIEFVKLRCAGKICTGAAYLRNFIVNHPAYEKDSYINSRINYDICKLIADIGK
GLIIPQELLGVFVDPYKERIKSDLRQINESQYVKSLAYKFISGEDYTQYLLLSEAIKDDQ
DYYTGTRRTNYEESSMDNNTLEFGKKLYQLSA
NT seq
2979 nt
NT seq
+upstream
nt +downstream
nt
atgggattcctcaaaattggaactccattaagttgggaggaagtgcaaaaagtaaaatcg
ctaatcaggttatatggcatactccagtttgttcatacgtacaaatgtaacaaagatcga
gtggatgaaaatatcatgtttggagacgaaatagaatacatcgttattcgaaatgatgaa
aattttaaagaatctgctgctctcttatgtgcaacagatttaattgatgaaatgatgaac
ttagaaagtgtcacctattgtcagtatggatcacattggactcctgaatattcctctttc
accattgagggcacaccctctgttcctttcaaatttgatataaattcatcaccctttgtt
gaagattgcatgcgcataaggagaatcaaactcaacaatgttctcagtgccattatggga
gaagtgcgggccatcactttgccttgcttcccaaacgctctcctagaaaatagcctactt
atggccaaaaggatcacccaagaaacgggcaagaggaagggtgacagggggaaaggtgct
atgggttcaggtggggacaccttggagacgccagcaatcgaacatgtgaagcaaaaacaa
gcggaaaagggacagggagagatggtcagacaggtcatcacggagggagagtataaaatc
acgctcaacgatagcacgcagacgtatgcggacgaggggaagtctacccagtttgtaaac
tcggatgtggttgcccaaaggaatgacgactcgttaatgcaggaaatgtgcggggatgaa
gttggcggcgcggaccaggcggaccaagcggaccaagcggaccaggcggaccaggcggac
caggcgggccactcgaatgaatcgaatgaatcaaagcaggccaaccaggcgagcacgccg
aaccaacccatcttcatcaacgaggccaaggaaaacctcctcttcgaatgcgacctgttc
aaacctgaacagacaaagaactacagcaacagctgcctcatcaccgacatggtgatcagt
ccgcacgccaggtacgtcactctaactaagaacataagaaaacgaagagggaccaaaatc
atttcatttaacgagatatacaaagatgagaacacagagaagctgcccaggtgggaacac
tcgctggacaaaacggacaggagacttttcaagaaaataaaaaaaaagtacgtcctcgat
gagcacttgatttggaacaaatctatgacgaataagaagagagtagaacccatcggtttg
gattttcctccaagtggagcagaagcggcatcgccagcagtggtagaagcgtcagagaat
cccagcgcagaggatgctctccccgcgccagacaacctaatcgatgaagtgataaaaaat
agcttgtttagcaacttggacgacgagaaggaccacatctacgtttacgatcggaagttt
atccaggagtactcggagaaatgcaagaatccaattaaaaattatgtttacctagatgca
atgttcttcggaatgagcatgtgttgtcagcaagtgactatgtcctttccaactatagat
gacgcgaagtatttatatgaccagctagctgttatcgcccccttgttcttagccctaacg
gcatcaaccccgtatttaggaggatttctcacagagacggacactcgatggagagtcata
tcaaacagtgtcgactgtagaacagaagaagaactagcatacatttcgaagccaagatat
tcaggcatatctttgtacatttctaatgagttgccacttaggaagaactaccatttctat
aacgacatagatgtggtgttagataaaaatgtgtatgataaattggtgaaagaaaatgtg
gatgattttttagctagacatgttgcttctctcttcgttagggaccccatcgtagttttt
gagggttcgtacagtgaaagggatatacagtcagttgaggagaggatgaagggcgagatg
ggttccgaaatgggaaaccagaaccccatcaacagcgtgtacctaagcgatgacttcaac
tttttggaggactacgaagagacggtgttgtcctcccatcagcattttgagaacttccaa
agtaccaattggaacagcgtgaggtttaagccaccacccatcctgagcaaccattgcaat
ggaacaagttccataggatggagagtagaatttcgcacaccagatattcagatcaccgat
tttgaaaacgcatcagttgttacgctcatcatggtattgtccaaatttatcctaaaggag
aagttgaacttatacattccgatgtcaatgttggaggaaaatcttttccgttccggtaac
agagatgccattttcaaggagaaattttatttcaggagagatttaacatatgatacggag
gataatgaagtggaggaaaagactttatatgatattttttttaacaaccacaatggtatt
tttttcctttgctccaagtatattgaggagcagttccgagaggggttactctcccatgca
gctaagaacaaaatagacgagtacattgaatttgtgaagctgagatgtgctggaaaaatc
tgcacaggtgctgcgtatttgagaaactttattgtgaatcacccagcgtatgaaaaggat
tcctacatcaatagcagaattaattatgatatttgcaagctgatagcagatatagggaag
gggcttatcatacctcaggaactgctgggcgtgtttgtggacccttacaaggaaagaatt
aaaagtgatttgaggcaaattaacgaaagccagtatgtgaagagtttggcctataagttc
atctccggggaagactacacgcagtacctgttgttgagcgaggctattaaggatgatcag
gattactacaccggtacgaggcgaaccaactacgaggagtcgtccatggataataacacg
ctggagtttgggaagaagctctaccagctgagtgcctag
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