Paramisgurnus dabryanus (large-scale loach): 135718769
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Entry
135718769 CDS
T10799
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
pdab Paramisgurnus dabryanus (large-scale loach)
Pathway
pdab00562
Inositol phosphate metabolism
pdab01100
Metabolic pathways
pdab04012
ErbB signaling pathway
pdab04068
FoxO signaling pathway
pdab04070
Phosphatidylinositol signaling system
pdab04081
Hormone signaling
pdab04140
Autophagy - animal
pdab04150
mTOR signaling pathway
pdab04210
Apoptosis
pdab04218
Cellular senescence
pdab04370
VEGF signaling pathway
pdab04510
Focal adhesion
pdab04620
Toll-like receptor signaling pathway
pdab04625
C-type lectin receptor signaling pathway
pdab04810
Regulation of actin cytoskeleton
pdab04910
Insulin signaling pathway
pdab04914
Progesterone-mediated oocyte maturation
pdab05100
Bacterial invasion of epithelial cells
pdab05132
Salmonella infection
pdab05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
pdab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
135718769 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
135718769 (pik3ca)
04370 VEGF signaling pathway
135718769 (pik3ca)
04068 FoxO signaling pathway
135718769 (pik3ca)
04070 Phosphatidylinositol signaling system
135718769 (pik3ca)
04150 mTOR signaling pathway
135718769 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
135718769 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
135718769 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
135718769 (pik3ca)
04218 Cellular senescence
135718769 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
135718769 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
135718769 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
135718769 (pik3ca)
04625 C-type lectin receptor signaling pathway
135718769 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
135718769 (pik3ca)
04914 Progesterone-mediated oocyte maturation
135718769 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
135718769 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
135718769 (pik3ca)
05100 Bacterial invasion of epithelial cells
135718769 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pdab04131
]
135718769 (pik3ca)
Enzymes [BR:
pdab01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
135718769 (pik3ca)
Membrane trafficking [BR:
pdab04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
135718769 (pik3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
135718769
NCBI-ProteinID:
XP_065097068
LinkDB
All DBs
Position
14:complement(9020627..9042893)
Genome browser
AA seq
1070 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRIQVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETKRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGAQSRALYVYPPNVESSPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYTQLPMD
NYTLLMPSYARRISTATPYMNGEASTKSLWTINSTLRIRILCATYVNVNIRDIDKIYVRT
GIYHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFD
HFSSPVKYPDMTTIEDHANWIISREMGYNYCQSGQSSRLARDHAMTEVDIEQLRQLSNRD
PLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMFCLLKDWPAIKPEQA
MELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKAL
TNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDI
LKQEKKDETQKVQMKFLVEQMRRPDFMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRP
LWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGC
LSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDLAIDLFT
RSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQ
DFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDD
IAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atgcctccaagaccctcctcaggagaactatggggcatccatttgatgccccccagaatt
caggtggactgtctgcttcccaatggcatgatcctaacactagagtgcctccgagaggcc
acccttatcactatcaagcatgaactttttaaggaggctaggaagtatcccctccatcac
ctgctgcaggaggagacctcctatattttcgtcagtgtaacgcaagaggcggagcgtgag
gagttttacgatgagacaaagagactttgtgacctccggctgttccagccgttcctgaag
gtcatcgaacctgtagggaacagagaggaaaaaatcctcaatcgagaaattggttttgcc
atcggtatgccggtttgcgagtttgatctagtgaaggatcccgaagtccaagacttcagg
agaaatattctcaacgtctgcaaagattcagtcgaactgcgagatgcgaatggagcacaa
agtcgggcactatacgtttatcctcccaacgtggagtcttcaccagagcttccaaagcac
atatatagcaaattagacaaaggtcaaatcattgtggttatctgggtgatcgtctctccc
aacaacgacaagcaaaagtacacgctcaagatcaatcacgactgcgtacccgagcaggtg
atcgccgaagccatcaggaagaaaacgagaagcatgctgttgtcggccgagcagctgaag
atgtgcgtgcaggaatatcagggcaagtacatcctcaaagtctgcgggtgcgatgagtac
cttctggagaagtaccccatcagccagtacaagtatgtgcgcagttgcattatgctgggt
cgaatgccaaatctcatgctaatgtccaaggacagtctttacacccagctgcccatggac
aactacaccctcctcatgccctcatacgcccggcgcatctccaccgcaacgccttacatg
aacggagaagcttcaaccaaatccctctggaccatcaacagcactctgaggatacgcatc
ctctgcgccacatacgtcaatgtgaacattcgggatattgacaagatttatgtgcggaca
gggatctaccatggaggagaacagctatgcgataacgtaaacacgcaacgtgtcccatgt
tctaacccgaggtggaacgagtggctgacctatgatatgtacattcctgatattcctcgg
gcagctcggctctgtctctccatctgttctgtgaaaggaaggaagggagcaaaagaggag
cactgtccactggcctggggaaacgtcaacctgttcgactacacacacacgctggtctca
ggaaagatggcactgaacctgtggcctgtcccacacggcctagaagacctcctcaatccc
atcggggtcacgggctccaaccctaacaaggaaaccccatgtctagagctggagtttgac
catttcagctctcctgttaagtaccctgacatgaccacaattgaagatcacgctaactgg
ataatttccagagagatgggatacaattactgtcagtctggacagagcagtaggctggcg
cgagaccacgccatgacggaggtagacatagagcaacttcggcagctgagcaacagggac
ccactttctgaaatcactgagcaggaaaaagacttcctatggaggcacaggcagtattgt
gtaaatataccagaaatcctgccgaagattctgctggcggtgaagtggaattctagagat
gaagttgcacagatgttttgccttcttaaagactggccagcgataaagccagagcaagcc
atggagttactcgactgtaactatcccgatccaatgatccgagactttgcagtccggtgc
cttgagaagtatctgactgatgataaactctctcagtacctcattcagctggttcaggtt
ttgaagtatgagcagtatcttgataaccccctggtacgatttctgctgaaaaaagctctt
accaaccagaggattggacacttcttcttttggcatttaaagtcggagatgcacaataaa
actgtgagtcagcggtttggtctgctgctggagtcgtactgtcgggcgtgtggcatgtac
ctgaagcacctgagcagacaagtggaagccatggagaagctgatcaacctcacagacatc
ctcaagcaggaaaagaaggatgaaacccaaaaggtgcaaatgaagttcctggtagagcaa
atgaggagaccggactttatggatgccctccaaaatttcacctctccgctcaaccccgcc
caccagctcggtaacctacgacttgaagattgcaggatcatgtcctcggccaaaagacct
ctgtggctgaactgggaaaaccctgacataatgtccgaactactcttccagaacaatgag
atcattttcaagaacggagatgacctacgtcaggacatgctgacattacagatcattagg
ataatggaaaacatttggcaaaatcaagggctggacctgagaatgcttccctatggttgc
ctctctattggagactgtgtgggtcttatagaggtggtgaggagttcccataccatcatg
cagattcagtgtaaaggaggtttaaagggagcattgcagtttaacagctcgacgctgcat
cagtggctaaaagacaagaacaagggcgagatgtacgacttggctatcgacttgtttaca
cgatcatgtgctggctattgtgtggccaccttcattctggggattggtgatcgacacaat
agcaacatcatggtgaaggacgacgggcagctgtttcatatagatttcggtcactttttg
gatcacaagaagaagaagtttggctacaaacgagagcgtgtgcccttcgttttaactcaa
gacttcttaatcgtgatcagcaaaggaacccaagaatgcactaaaaccagagagtttgag
aggtttcaggagatgtgctacaaggcctatttagctatcaggcagcacgccaacctgttc
ataaaccttttctccatgatgctgggctcaggcatgccagagctgcagtcttttgacgac
atcgcttacatccggaagaccctggcactggacaaaaccgagcaggaggccctggactat
ttcatgaagcagatgaatgacgctcaccatggcggatggaccactaagatggactggatc
ttccataccatccgacaccatgcccaaaactga
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