Paramisgurnus dabryanus (large-scale loach): 135780894
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Entry
135780894 CDS
T10799
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
pdab Paramisgurnus dabryanus (large-scale loach)
Brite
KEGG Orthology (KO) [BR:
pdab00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pdab01001
]
135780894 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pdab04131
]
135780894 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pdab04147
]
135780894 (lrrk2)
Enzymes [BR:
pdab01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
135780894 (lrrk2)
Protein kinases [BR:
pdab01001
]
Serine/threonine kinases: TKL group
LRRK family
135780894 (lrrk2)
Membrane trafficking [BR:
pdab04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
135780894 (lrrk2)
Exosome [BR:
pdab04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
135780894 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
COR
Roc
Ras
LRR_14
Beta-prop_EML_2
WD40_CDC20-Fz
LRR_9
LRR_LRWD1
LRR_13
LRR_6
LRR_NXF1-5
WDR55
MMR_HSR1
Beta-prop_RSE1_2nd
Motif
Other DBs
NCBI-GeneID:
135780894
NCBI-ProteinID:
XP_065147263
LinkDB
All DBs
Position
23:27216331..27262693
Genome browser
AA seq
2517 aa
AA seq
DB search
MADKEELKIRLKKLLVRLNLQEGKQLGTMVQIVQDLLFLSHTDDCVELFADQNVHVSLML
VLSTHFNSKVQQVGWSLLCRLMEICPSTLDKLATPADLDLIGVHQHILKMLSMYHKDAKM
MMVGLRSLALLLKSDEIAMQVLDEEEIDVFFLVLRAMRSFSDSEEVQLQGCGALQLLLQR
VSVDHLVEFVEKKDHEVVMNALIRFIDSENVVLQALRVLIVLAAPASNVEILMSKPVKCY
TVVCRAMEAWLESEAIQEAGCCLLQKFTSESYYNILVLNGVHRVAMKACISYPGNATVQA
AALSCLSMLAESIVQNDALDREFSEEDKEQEMFVRKENSHVEESLIWTETCYTAFERHAD
DATVQEAACWALNSLLLHCNTSSYVELEGRPSLHILIMASMLFHSSCVPVFQAASCTLRT
LIQHNSRMRAQLLSHGIHFNIVNLMKKHSNSSEVCESACKLLHTLFQGARAGLDEGELVL
RQIMIALKTHNFLPEVQLEGFRASLVLLNPDRSLRENGISVADPDIVDICLRVLKNQYVL
EGAHTVYLEALNRFINSEEIQKCGLTVLTTLADCFGAVDLMCQQGAIDTVLHTLQMFPLK
RDIHYWGLSLLFHLISKKKLSPIMVPVVASVVVSSVRQHKDDASMLLKGFQVVWKLLDTC
SCAAAELQKEGFEKEIFQILRENSADQRKDPLQGISCLCLMKMVADSEIMYMLLERACED
GDVVMTECLIQLGADINKKTKSDSLINQVCAHGAPLALLELLVSAGVHEQQLRGALTVCL
RRGDDPAVTLLLSRLGLDHSNSALCLGSFRLGHIKASWLSSLLSERKTIPPTNGRNIQGQ
ALARQILLFQRRKGFVGVTRHPSDVSTSGYYTDEESDNSYMSLDDSLAFICDDMESDGSD
GPPHGSFLHGDSPEISRKPALRQHRQHDTFAQGYHGDTNPSVPQKFGWSSHNRGSTEISS
PTAVLLGIDKEPIRLLDLSGNELDNLSCLLDESSVKQQIENLFRLDLSSNRLSEVPSALC
QSLRSLTRLDLQGNQLESLPAELLGLPALSMLNVSRNRIGPLLLLDPTVRCPTLRQLNLS
FNHITVFPFQLGQTTDKLEELSLEGNQISELSLPLSLSELRALDVSKNQVRLISENFLTE
CPKMETFNASVNQISSFLHLPSKITTLKLAENNFTNIPDVIIRLPHLRSLDMRNNSIRVL
PGPGVWASGNMRELMFSHNHIPVLDLSGPVYKWARLEKLHLKSNRLTEIPPQIGLLEDLT
SLDVSQNKDLRSFPNEMGKLVRLWDLPLDGLQLQMDLKHIGSKTKDIIRFLQQRLKKAVP
YYRMKLMVVGSPCSGKSSLIQQLMRLKRSQWWSNQQSTGISVIDWTIRNKDRRSMLLNVW
EFSGGEECSGCHPHFMSSRALYLVLYDLSKGPSEIDSIKPWLFNIKAVAGQCPVIVVGTH
ADLCEERHLQDCVLKLREELMFQQEFPVIKENHMLCACEESESISKLRKAIYKELVAFKI
QGQPVMGELIPDCYVELEKRVLQERTRVPAKFPVLRHSRLLEIIQETQLQLEEGELPHAV
HFLSEAGVLLHFDDPALQLKDLYFIDPQWLCNIISQTLALRSSGQLESARGVVQRSTIKE
FLEKSRCFPQDQLTQYFKLLEKFQIALPFGDDQLLIPSSLSDDRPVIELPYYENSEVIVR
LYEMPYFPMGYWSRQISRLLDMSSFMLNGREKALRPNRIYWRKGIYLSWSAEAYCIVEAS
SLEENPASFIKITVPCSRKGRVLLGQVVDHIDSLLEEWFPGLLATDVNGTGEALLKKWAL
YSFSDGQNYQKILLEDLLFNINPDGLLVNPEDPSCTLPISQISPDLVLSDQPSSIILDPE
QLEMELSAEYLLGDGGFGSVYKAVYKNEEVAVKIFNKHASALYVHRLVRQELIVLGKLQH
PSLVGLLAAGCNPHILVMELAPCGSLDLLFERKTSSLNRKLQHRIALHVADGLRYLHASM
IIYRDLKPHNILLFNLKTDCEVIAKITDYGIAQYCCSMGVRSSEGTPGFRAPEVARGNVI
YNVQADVYSFGLLMYDLLTYGERISDGMKFPSEFDEVAVQGKLPDPVKDYGCSPWPGFEC
LMRDCLRENPQDRPTSIQVFDRLNSADMLCLLRERTVLGLPGECLAVSCSAGEKDAHVWI
GGGSSSQKLGCVTSLDLETGTSLQQEIDSSPVLCLVMVRAPGSHHDWLVAGTQSGSLFIM
DTKSAEILHCLKSVKDSVTSLYFHSDLQHRCQKSYLLVGTADGTLVIYEDSVLKMVNGTP
VKTLQVGDVRTPLMCLGPSSHFQERRALWAACGTRVISFTVEYDICKSIDTKPKQLLLHH
GRFSGDACILRLAVDKHVYVSKTGSNSVEVWDKKSDRMVNLIDCAQLLGHDSARKVQSED
TVKSLLVQHSGTLWIGTRAGHILLVETSSCQLLQSISPHCHSIRCMSSATLETLNRSSVV
LVLGRRQRMQDQIKTPSSQDSVLMVWSGSLPLEVKDLSRHQELRDNVTSKIRETLHD
NT seq
7554 nt
NT seq
+upstream
nt +downstream
nt
atggcagataaagaggagttaaagatcagattgaagaagctgctggtgagactgaatcta
caggagggaaagcagttgggtactatggtccagatcgtacaggacctcctgttcttgtcc
catacagatgactgtgttgagttgtttgctgatcaaaatgttcacgtgtctctgatgctg
gtgctgtcaactcattttaacagcaaagttcagcaggttgggtggtctctgttgtgtcgt
ctgatggaaatctgtccctcaactctggacaaactggcaaccccagcggaccttgacttg
ataggggtgcaccagcacatactgaagatgttgtccatgtatcataaagatgccaaaatg
atgatggttggtctcagaagtctggctctcttactgaagtcagatgagattgcgatgcag
gttctggacgaggaagaaatagacgtgtttttcctggttctgagggcaatgaggtcattc
agtgatagtgaagaggttcagctgcagggatgcggtgctctacaactgctgcttcagaga
gtttcagtagatcatctggtggagttcgttgagaagaaggaccatgaggtggttatgaat
gctctcatcaggtttatagacagtgaaaatgtggtcctccaagctttgagggtcctcatc
gtgctggcggctccagcaagcaatgttgagatactgatgtccaaacctgtcaagtgctac
actgtggtgtgtcgggccatggaagcgtggctggaatctgaggccatacaggaggctgga
tgctgtttgttacagaaatttacatcagagagttactataatatcttggtactgaatgga
gttcacagagtggctatgaaagcttgcatttcttaccctggaaatgcaacagtacaggct
gctgctctgtcttgtctgagcatgctcgctgagtctattgttcagaatgacgctctggac
agagagttcagtgaggaggacaaggaacaagaaatgtttgtgaggaaagaaaacagccat
gtggaagaaagccttatatggacagaaacctgttacacagcttttgagcgacatgccgat
gatgccacagtacaggaagctgcttgttgggccttaaacagcttgctgctccattgcaac
acttctagttatgtggaactggaaggaaggccttctcttcatatcctcattatggcttca
atgttgtttcattcatcgtgtgtgccggtgttccaagctgcttcgtgcacactgcgcaca
cttatacagcacaacagtaggatgagagctcagctgttgtctcacggcatacatttcaac
attgtgaatttgatgaagaaacactcaaactccagcgaagtgtgtgaaagtgcctgcaaa
ctgcttcacacacttttccagggagcgagagctggtctagatgaaggggagctggttctg
cgtcaaattatgattgctcttaagacacacaacttccttcctgaagtccagctggagggg
ttcagagcaagtctagttcttctcaatccagacaggagtttaagggaaaatggcatttca
gtggcggatcctgacattgtggatatctgcctgcgggtgctgaagaaccagtatgtgcta
gagggagctcacactgtttatctagaggcacttaataggtttatcaacagcgaggagatt
cagaagtgtgggcttactgttctcaccactttagctgactgttttggtgctgttgacctt
atgtgccagcagggggcgatagacacagtccttcacacactgcagatgtttccactgaaa
cgtgatattcattactggggtctaagcctcctatttcacctaatctccaaaaagaaactt
tctcctattatggttccggttgtggcttctgttgtggtcagctctgtacggcaacacaaa
gacgacgcaagcatgctcctcaagggatttcaggtggtgtggaagttgttggacacctgt
tcatgtgctgcagcagaactccagaaagaggggtttgagaaagagatctttcagattttg
agagagaacagcgcagatcagcgcaaagatccattacagggtattagttgcctgtgtctg
atgaagatggtggcagatagtgagatcatgtacatgttgttggagagggcatgtgaagat
ggtgatgtggtcatgacagagtgtctcatacagctgggtgctgacatcaacaagaaaaca
aagagtgattctctcataaatcaggtctgtgctcatggagctcctctggccctgcttgag
ctgctggtttcagcaggcgttcatgagcagcagctgcgcggcgctttaaccgtatgcctc
aggagaggagacgacccggcggtcaccctcctcctcagccgtctggggctggaccacagc
aacagcgccctctgcctcgggagcttccgtcttgggcacattaaggcgagctggcttagc
tctctgctgtctgagcgcaagaccatcccaccaaccaacggcaggaacattcaaggtcag
gcattggccagacagatcctgttattccagaggagaaaaggctttgtgggagttaccaga
caccccagtgatgtcagcacatcaggatattacacagatgaggaaagcgacaactcttac
atgtctttagatgacagcttggccttcatttgtgatgatatggagagtgatgggagtgat
ggacccccgcatggatcatttcttcacggtgattcaccagaaataagcagaaaacctgct
ttgagacaacaccgtcaacatgatacatttgcacagggataccatggagacactaatcca
agcgtccctcagaagtttggctggagctctcacaatagagggtcgactgaaatctcttct
cccaccgctgttttgctgggcattgacaaagaacccatccgtctgctggatctgtcaggg
aatgagttggacaatctgtcttgtttactggatgaaagctctgtcaaacagcagattgag
aacctctttcgactggatttgagtagcaacaggctgtctgaggtccccagcgctctatgt
cagagtctacgaagtttgacgcgacttgatctccagggtaaccagttggagtcacttcct
gctgaacttctaggccttcccgcactgagcatgctcaatgtgtcccgcaaccgaattggt
ccacttttattgctggaccccactgtgcggtgcccaaccttacgccaactaaatctgtcg
tttaatcacatcactgtcttcccattccaactaggtcagaccacagacaaactagaggag
ctctcattggagggaaatcaaatatcagaactatctttacctctgtctctgtctgaactg
agagctttagacgtcagtaaaaatcaagttagactgatttcagaaaacttcctgacagaa
tgtcccaagatggagacatttaatgcttcagttaaccaaatcagttcatttttgcacctt
ccttcaaaaataaccacgcttaaactagcagagaacaattttacaaacattcctgatgtg
atcatccgcctgccgcatttgcgttcattggacatgagaaataacagcatcagagttctt
ccgggtccaggcgtgtgggccagtgggaatatgagagagcttatgttcagtcataatcac
atccctgtactagatctcagcggtcctgtgtacaaatgggctcgactagagaaactccac
ctgaagtccaacagactcactgagattcctcctcagatcggtctgctggaggacctgacc
tctctggatgttagtcagaataaagatttgcgctcttttccgaatgagatggggaaactg
gtacgtttgtgggatttgcctttggacggcctgcagctccagatggacctcaaacacatc
ggcagcaaaacaaaagacattatcaggttcctgcagcagcgtttgaagaaagctgtccct
tattaccgcatgaaactcatggtggttggcagcccatgcagtgggaaaagctctttgatc
cagcagctcatgaggctcaagcgctctcagtggtggtccaatcaacagtcaacaggcatc
agtgtcatagactggaccatcagaaacaaagacaggaggagcatgctgctgaacgtttgg
gagttttcaggtggtgaggagtgcagtggatgtcaccctcatttcatgagctctcgagct
ctgtatctcgtgctgtatgaccttagtaaaggaccgagtgagatagatagcatcaaaccc
tggctcttcaacattaaagctgtagctggtcagtgtcctgtgattgtggtcggtactcat
gcagatttatgtgaagagcgccacctgcaggactgtgtgttaaagctgcgagaggaactg
atgtttcagcaggagtttccagtgataaaagagaaccacatgctttgtgcctgtgaggag
tctgaatctatcagcaaattacgcaaagccatctacaaagagctcgttgcatttaagatc
cagggtcagccggtgatgggtgagctgatcccagactgttacgtggagttggagaagaga
gttttgcaggagaggacccgtgtcccagccaaattcccagtgctcagacatagcagactg
ctggagatcatacaagaaacacaactgcagctggaggagggagagttaccgcacgccgtt
cacttcctcagtgaggccggtgtccttttgcactttgatgatccagcgttgcagctaaag
gacttgtactttattgacccacagtggctttgcaacatcatttcacagactttggcattg
aggagctcaggccagttggagagcgcaagaggggtggtgcagcgctccaccataaaggag
tttctggagaaaagccgctgtttccctcaagaccaactcacccagtactttaaactgcta
gagaagttccagattgcgttgccattcggagatgatcagctacttatacccagcagcctc
tcagatgacaggccagtgattgaacttccttactatgagaactcagaagtgattgttcgc
ctctatgagatgccctatttccccatgggttactggtccagacagatcagccgcctgctg
gatatgtcctcattcatgctgaatggaagagagaaagcgctgaggccaaaccgcatctac
tggagaaagggcatctatctgagttggtctgctgaagcttattgtattgtggaagcctct
tccctggaggaaaacccagctagcttcatcaagatcaccgtcccctgctctcgcaaaggt
cgtgtgttgttgggacaggtcgtggatcacattgattctctgctggaagagtggtttcca
ggtctcctcgccactgatgttaacggcactggtgaggcgctactgaagaaatgggctcta
tacagctttagtgatggacaaaactaccagaaaatcctactggaagatctgcttttcaac
attaatccagatggattgctggtgaacccagaggatcccagttgtactctgcccatctct
cagatatctccagatctggtactaagtgaccagccatccagcatcatactggatccagaa
cagctggagatggagctgtctgcagaatatctgctgggtgacggaggtttcgggtctgta
tataaagctgtatacaagaatgaagaggttgccgtgaagattttcaacaaacatgcatct
gcactttatgttcaccgactggtgcgacaagaactgatagtactcgggaaactgcagcac
cccagtctggttggactgttggccgccgggtgcaaccctcacatcctggtgatggaattg
gccccgtgcggttccctggacttgctctttgagcggaaaacatcaagccttaaccggaaa
ctccagcacaggatagcactgcacgtggcggacggtcttagatatttgcacgcttcaatg
ataatctaccgggatctgaagccacacaatattctcctgtttaacctgaagacagactgt
gaggtcatcgcaaagattacagattacggcatagcgcagtactgctgcagtatgggcgtc
cgcagctcagagggaaccccaggctttagagcacctgaggtggctcggggaaatgtcatc
tataacgtccaggcagatgtgtactcattcggcctgctgatgtatgacctattgacctac
ggcgagcgcatttcagatgggatgaagtttcccagtgagtttgatgaggtggctgtacag
ggaaagctaccagatccagtgaaagactatggctgttctccgtggccggggttcgaatgc
ttgatgagggactgtttgagagaaaacccccaggacagacccacttccattcaggtgttt
gatcgtctgaactctgcagacatgctgtgtctactgcgagagcggacggtgttgggtttg
cctggtgagtgtttggctgtctcctgttcggcgggagaaaaagacgcccatgtgtggatc
gggggcggcagcagtagccaaaaactgggatgtgttacgtcactggatcttgagacagga
acaagcttacaacaggagattgacagcagtcctgttctgtgtctggttatggttcgagct
ccaggatcacatcatgactggttagttgctggtactcagtcgggttcactctttattatg
gacaccaagagtgcagagattcttcattgtctgaagagcgtgaaggactccgtaacatct
ctgtacttccacagtgaccttcagcacagatgccaaaagagttacctgttagtggggaca
gcagatggaacgctagtcatttatgaagactcagtcttaaagatggtgaatggtactcca
gtaaaaacgctgcaagtcggtgatgtgaggacccctttgatgtgtctcggcccatccagt
cactttcaggagcgcagagctttgtgggcagcgtgcggtactcgtgtgatctccttcact
gtggaatatgacatctgcaaaagcatagacaccaaacccaaacagctccttctgcaccat
ggtcgattcagcggtgatgcgtgtatattacgtttagcggtggacaaacacgtgtatgtg
agtaaaacaggaagcaacagtgtggaggtctgggacaagaagagcgacaggatggtaaac
ctcatcgactgcgcacaattactcggacacgattctgccagaaaggttcagagtgaagac
accgtcaaatcactgctggttcagcacagcggtactctttggatcgggactagggcagga
cacatcctgttagtggagacctccagctgtcaactactgcagagcatcagcccacactgc
cactccatacgctgcatgagttcggccacgctcgaaacactaaaccgaagcagtgttgtt
ctagtcttgggtagacggcaacgcatgcaagatcaaatcaaaacaccatccagtcaggat
tcagtgctgatggtgtggagcgggtcacttcctctagaggtcaaagatctgagcaggcac
caagagcttcgagacaacgtcaccagcaaaataagagagacacttcatgactga
DBGET
integrated database retrieval system
