Clostridioides difficile 630: CDIF630_01126
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Entry
CDIF630_01126 CDS
T03885
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pdc
Clostridioides difficile 630
Pathway
pdc00290
Valine, leucine and isoleucine biosynthesis
pdc00660
C5-Branched dibasic acid metabolism
pdc01100
Metabolic pathways
pdc01110
Biosynthesis of secondary metabolites
pdc01210
2-Oxocarboxylic acid metabolism
pdc01230
Biosynthesis of amino acids
Module
pdc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pdc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CDIF630_01126 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CDIF630_01126 (leuC)
Enzymes [BR:
pdc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CDIF630_01126 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CDIF630_01126 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AJP10676
UniProt:
Q18AJ2
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Position
1139304..1140581
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AA seq
425 aa
AA seq
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MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIREFEKLGIEDVYDKTKV
VMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGIEHVLLPEKGIVTAGDVII
GADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGAIKFVLKNKPNKWISGKDIIL
HIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMAIEAGAKNGIFPVDDKTMEYINS
HKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETVAFPHLPENTRTVDEIDKDIKIDQV
VIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIFPGTQKVYLEAIEKGYITTFIEAGAAV
STPTCGPCLGGHMGILAAGEKSISTTNRNFVGRMGHVDSEVYLASPAVAAASAITGKISK
PSEII
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atggggatgactatgacgcagaaaatattagccaaacatgctaaattaaatgaagttaag
aaagggcaattaatcgaagcagatttagatgtagttttaggtaatgatataacatcacca
gtagccattagagaatttgaaaaattaggaattgaagatgtttatgataagactaaagta
gtgatggttttagaccactttacacctaataaagatataaagagtgcagaacaatgtaaa
tttacaagaagtttcgcaaaatcaaaaggagttgtaaatttttttgatgtaggagatatg
ggaatagagcatgttcttcttcctgaaaaaggtatagtaactgctggagatgtaattata
ggtgctgactctcatacttgcacatatggagcattaggagcattttctactggtgtaggt
tcaactgatatgggagcaggtatggctacaggaaaatgttggtttaaggttcctggagca
ataaaatttgttttgaaaaataaaccaaataaatggataagtggtaaagatataatactt
catataataggggagataggtgttgatggagcactttacaagtcaatggaattttgtgga
gatggagtagaatacttatctatggatgatagatttactatttgtaatatggcaatagaa
gcaggagcaaaaaatggaatttttccagtagacgataagactatggaatatataaattca
cataagtgttcaactatgacaaaagatgtaaatatatatgaagcagatgaagatgcagtc
tatgatgaagtatacgaaatagatttagccaaactaaaagaaacagtagcctttcctcat
cttcctgaaaatactagaacagtagatgagatagataaggatataaagatagaccaagtt
gtaataggctcttgtacaaatggaagaatatcagaccttgaagtagtagctgagataatg
aaaggcaaaaaagtagcagatggagttagagttatgatatttcctggaactcaaaaagta
tatcttgaagctatagaaaaagggtatattaccacttttatagaggcaggagcagcagtt
tctacaccaacttgtggtccatgtctagggggacatatgggtatacttgcagcaggagaa
aaatccatttcaacaacaaataggaatttcgtaggaagaatggggcatgttgattcagag
gtgtatcttgcaagcccagctgtagcagcagcatcagctataactggaaaaatatcaaaa
ccatcagaaataatttaa
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