Phyllostomus discolor (pale spear-nosed bat): 114488551
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Entry
114488551 CDS
T07739
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X2
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521
EGFR tyrosine kinase inhibitor resistance
pdic01522
Endocrine resistance
pdic04010
MAPK signaling pathway
pdic04014
Ras signaling pathway
pdic04015
Rap1 signaling pathway
pdic04066
HIF-1 signaling pathway
pdic04068
FoxO signaling pathway
pdic04081
Hormone signaling
pdic04114
Oocyte meiosis
pdic04140
Autophagy - animal
pdic04144
Endocytosis
pdic04150
mTOR signaling pathway
pdic04151
PI3K-Akt signaling pathway
pdic04152
AMPK signaling pathway
pdic04211
Longevity regulating pathway
pdic04213
Longevity regulating pathway - multiple species
pdic04510
Focal adhesion
pdic04520
Adherens junction
pdic04550
Signaling pathways regulating pluripotency of stem cells
pdic04730
Long-term depression
pdic04913
Ovarian steroidogenesis
pdic04914
Progesterone-mediated oocyte maturation
pdic05200
Pathways in cancer
pdic05202
Transcriptional misregulation in cancer
pdic05205
Proteoglycans in cancer
pdic05214
Glioma
pdic05215
Prostate cancer
pdic05218
Melanoma
pdic05224
Breast cancer
pdic05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114488551 (IGF1R)
04014 Ras signaling pathway
114488551 (IGF1R)
04015 Rap1 signaling pathway
114488551 (IGF1R)
04066 HIF-1 signaling pathway
114488551 (IGF1R)
04068 FoxO signaling pathway
114488551 (IGF1R)
04151 PI3K-Akt signaling pathway
114488551 (IGF1R)
04152 AMPK signaling pathway
114488551 (IGF1R)
04150 mTOR signaling pathway
114488551 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
114488551 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
114488551 (IGF1R)
04140 Autophagy - animal
114488551 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
114488551 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
114488551 (IGF1R)
04520 Adherens junction
114488551 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
114488551 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
114488551 (IGF1R)
04914 Progesterone-mediated oocyte maturation
114488551 (IGF1R)
09156 Nervous system
04730 Long-term depression
114488551 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
114488551 (IGF1R)
04213 Longevity regulating pathway - multiple species
114488551 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114488551 (IGF1R)
05202 Transcriptional misregulation in cancer
114488551 (IGF1R)
05205 Proteoglycans in cancer
114488551 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
114488551 (IGF1R)
05214 Glioma
114488551 (IGF1R)
05218 Melanoma
114488551 (IGF1R)
05215 Prostate cancer
114488551 (IGF1R)
05224 Breast cancer
114488551 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114488551 (IGF1R)
01522 Endocrine resistance
114488551 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pdic01001
]
114488551 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pdic04090
]
114488551 (IGF1R)
Enzymes [BR:
pdic01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
114488551 (IGF1R)
Protein kinases [BR:
pdic01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
114488551 (IGF1R)
CD molecules [BR:
pdic04090
]
Proteins
114488551 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
114488551
NCBI-ProteinID:
XP_028358047
UniProt:
A0A6J2KRI7
LinkDB
All DBs
Position
12:36177194..36398213
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSLTSLWGLLFFSAALSFWPTSGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGD
LCPGTVEEKPLCEKTTINNEYNYRCWTTHHCQKTCPSACGKRACTENSECCHPECLGSCS
APDDDAACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANILNAESSDTEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFRGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTNTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPSNKDMEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDSYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDLGQIANTTMSSRIRNSTMPDTYNVTELEEPETEYPFFEA
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVPRQEYRKHGGARLNRLNPGN
YTARIQATSLSGNGSWTEPVFFYVQAKTTYENFIHLIIALPVAALLIVGGLVIMLYVFHR
KRNSNRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPAFHPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIIGSIKDELEPGFQEVSFYYSDENKPPDTEELDLEPDIMESVPLDPSASACSLPLPDRY
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERPLPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccctgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgttctggccgacgagtggagaaatctgcggccccggcatcgacatccgc
aatgactaccagcagctgcggcgcctggagaactgcacggtgatcgagggctacctgcac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggcgacctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcgggctgtacaacctgcggaacatcacccggggggcc
atccggatcgagaagaacgccgacctctgctacctgtccaccgtggactggtccctcatc
ctggacgcggcctccaacaactacatcgtgggcaacaagcccccgaaggagtgcggggac
ctgtgtccggggacggtggaggagaagcccttgtgtgagaagaccaccatcaacaacgag
tacaactaccggtgctggaccacccaccactgccagaaaacgtgcccgagcgcgtgcggg
aagcgggcctgcacggagaacagcgagtgctgccacccggagtgcctgggcagctgcagc
gcgcccgatgacgacgcggcctgcgtggcctgccgccactactactacgccggcgtctgc
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatcctcaatgccgagagcagcgacaccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaatggcacccagagcatgtac
tgcatcccctgcgaaggcccttgccccaaggtctgcgaggaagaaaagaagacgaagacc
atcgactcggtgacatccgcgcagatgctccaaggctgcaccatcttcaggggcaatttg
ctcattaacatccgacggggcaataacattgcctcggagctggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccactcccacgccttggtctccttgtcc
ttcctcaagaaccttcgcctgatcttaggagaggagcagctcgaggggaactactccttc
tacgtccttgacaaccagaacctgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaggcgggcaagatgtacttcgccttcaaccccaagctgtgcgtctccgaaatctac
cgcatggaggaggtgacggggaccaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagagggcctcctgtgagagcgacgtgctgcacttcacctccaccaacacc
tggaagaaccgcatcatcataacgtggcaccggtaccggcccccggactaccgggacctc
atcagcttcactgtctactacaaggaggcgcccttcaaaaacgtgacggagtacgacggc
caggacgcctgcggctccaacagctggaacatggtggacgtggacctgccctccaacaag
gacatggagccgggcatcctgctgcacgggctgaagccctggacgcagtacgcggtgtac
gtgaaggccgtgaccctcaccatggtggagaacgaccacatccgcggggccaagagcgag
atcctgtacatccgcaccaacgcctcagttccttccatccccctggacgttctctcggcg
tccaactcctcctctcagctgatcgtgaagtggaacccgccgtcactgcccaacggcaac
ctgagctactacatcgtccggtggcagcagcagccccaggacagctacctgtaccggcac
aattactgctccaaagacaaaatccccatccggaagtacgccgacggcaccatcgacatc
gaggaggtgacggagaaccccaagactgaggtgtgcgggggcgagaaggggccgtgctgc
gcctgccccaagaccgaggcggagaagcaggccgagaaggaggaggccgagtaccgcaag
gtcttcgagaacttcctgcacaactccatcttcgtgcccagacccgagaggaagcggaga
gacctcgggcaaattgccaacaccaccatgtccagccgaatccgaaacagcacgatgccg
gacacctataatgtcacagagctggaggagccggagacggagtacccgttcttcgaggcc
agagtggacaataaggagagaacggtcatttccaacctgcggcctttcaccctgtaccgc
atcgacatccacagctgcaaccacgaggccgagaagctgggctgcagtgcctccaacttt
gtctttgcgaggaccatgcctgcagaaggagcagacgacattcccgggccggtgacctgg
gagccgaggcctgagaactccatcttcctgaagtggccggaacccgagaatcccaacggg
ctgatcctgatgtacgagataaaatacggctcgcaggtcgaggatcagcgagaatgcgtg
cccaggcaggagtacaggaagcatggaggggcccggctgaaccggctcaacccggggaac
tacacggcccggatccaggccacctctctgtctggcaacggctcgtggacggaacccgtg
ttcttctacgtccaggccaaaaccacgtacgagaacttcatccacctcatcatcgcgctg
ccggtcgctgcgctgctcatcgtgggagggctggtgatcatgctgtacgtcttccacagg
aagcggaacagcaacaggctggggaatggcgttctctacgcttccgtgaacccagaatat
ttcagcgcggcggacgtgtacgtgccggacgagtgggaggtggcccgcgagaagatcacc
atgagccgggagctgggccagggctccttcgggatggtgtacgagggggtcgccaagggc
gtggtcaaggacgagcccgagacccgggtggccatcaagaccgtcaacgaggccgcgagc
atgcgcgagcgcatcgagttcctcaacgaggcttcggtgatgaaggagttcaactgccac
cacgtggtgcgtttgctgggcgtggtgtcgcagggccagccgacgctggtcatcatggag
ctcatgacgcggggagatctcaaaagctatctcaggtctctgcggccggaaatagagaat
aacccagccttccatcccccgagcctcagcaagatgatccagatggccggggagattgcg
gacggcatggcgtacctcaacgccaacaagttcgtgcaccgagacctcgctgcccggaac
tgcatggtggccgaagacttcacggtcaagatcggagatttcggcatgacaagagacatc
tatgagactgactattaccggaaaggagggaagggccttctgcccgtgcgttggatgtcc
cccgagtccctcaaggacggcgtgttcaccactcactccgacgtctggtccttcggggtc
gtcctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaatgagcaa
gtcctgcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgagctcatgcgcatgtgctggcagtacaaccccaagatgaggccctccttcctg
gagatcatcggcagcatcaaagacgagttggagcccggcttccaggaggtgtccttctac
tatagcgacgagaacaagccgcccgacaccgaggagctggacctggagccggacatcatg
gagagcgtgccgctggacccctcggcctccgcgtgctccctgccgctgcccgacagatac
tcaggacacaaggccgagaatggcccgggccccggagtgctggtgctgcgggccagcttc
gacgagaggcagccttacgcgcacatgaatggcggccgcaagaacgagaggcccctgccc
ctgccccagtcgtccacctgctga
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integrated database retrieval system
