Phyllostomus discolor (pale spear-nosed bat): 114490158
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Entry
114490158 CDS
T07739
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04020
Calcium signaling pathway
pdic04022
cGMP-PKG signaling pathway
pdic04270
Vascular smooth muscle contraction
pdic04371
Apelin signaling pathway
pdic04510
Focal adhesion
pdic04611
Platelet activation
pdic04810
Regulation of actin cytoskeleton
pdic04921
Oxytocin signaling pathway
pdic04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
114490158 (MYLK)
04020 Calcium signaling pathway
114490158 (MYLK)
04022 cGMP-PKG signaling pathway
114490158 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
114490158 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
114490158 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
114490158 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
114490158 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
114490158 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
114490158 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pdic01001
]
114490158 (MYLK)
Enzymes [BR:
pdic01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
114490158 (MYLK)
Protein kinases [BR:
pdic01001
]
Serine/threonine kinases: CAMK group
MLCK family
114490158 (MYLK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
BiPBP_C
Ig_4
C2-set_3
Ig_DSCAM-DSCAML_C
Kinase-like
Kdo
DUF5898
AvrM_N
Ig_J_second
Motif
Other DBs
NCBI-GeneID:
114490158
NCBI-ProteinID:
XP_035874087
UniProt:
A0A7E6D4C4
LinkDB
All DBs
Position
2:complement(102718840..103010096)
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AA seq
1965 aa
AA seq
DB search
MAMGDVKLAASTHVSKSSLGMDHSRAGPMPLTEAPAFISPPRNLCIKEGATAKFEGRVRG
YPEPRVAWHRNGQPITSGGRFLLDCGIRGSFSLVIHAVCEEDTGKYTCEATNGSGARQVT
VELTVEGGFVKKYGQLASKTMGDRFISPTAETRPSIWGECPPKFATKLGRAVVREGQMGR
FSCKITGRPQPQVTWLKGDVPLQPSARVSMCEKNGMQVLEIHKVSQDDVGVYTCLVANGS
GKASMSAELTIQGLDNANRPFLRGVKAASSDIRKEVTNGITQGPKLDSVETTAEHRNCSS
IQKGGSPTWATGSQPQSPMESKLEPSGDSPRKTLRTPVLQKTSSTITLQATKVQLEPRAP
VSGSLLPSREEREKPSAPPPATLPTRPSGLGTQEVVNKVATRKIPMESRRDSTFPKFESK
PQSQEVHEDQTVQFRCEVSGIPKPQVTWFLEGAPVRRREGTMEIYEDGGSHYLCLLRARA
RDSGNYSCTASNVRGQVSCDWTLLVKKLAEVEVAPSLSSVLKDCTVIEGQDFVLQCSVQG
TPVPQITWLLNGQPIQYARSTCEAGVATLHIQDALPEDNGTYTCLAENPLGQVSCSAQVT
VHEKKSDGKREFLLPAAASKPAAPRFLQGLSDLRVMDGSQVTMTVQVSGNPPPEVIWLHN
GNEIQESEDFHFEHRGTRHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPQDGT
QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKVLSGDTGHFEVLQNEDVFTL
VLKNVQPWHAGQYEILLKNQVGECSCQVSLMLQSSPTRAPPRGRVPASCEGLCGQGAGAD
GGDGDCYGTLRPSWPAGGQGWPEEEDGEGVRGVLKRRVETRQHTEEAIRQQEVEQLDFRD
LLGKKVSTKTLSEEELKEIPAEQMDFRANLQRQVKPKMVSEEERKVHSPQQVDFRSVLAK
KGTPKTPVPEKVPPAKPATPDFRSVLGSKKKLPAENGSNSAEALNAKVAESPKSMGNAKP
SEPPKPLGNAKPADTLKSVGNTKPAETLKPVGNTKPAETPKPVGNAKPAETLKPVGNAKP
VETPKPVGNAKPAETLKPVGNAMPAETLKPAGKEELKKEVKNDVNCKREHSGATDNEKRP
ESRGTAPAFTEKLQDVHVAEGEKLLLQCQVSSDPPATITWTLNGKVLKTTKFIILSQEGS
LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTMDDAPASENAKAPEMKARRPKSSLP
PVLGTESDATVKKKPTPKTPLKAAMPPQIVQFPEDQKVRAGESVELLGKVTGTQPITCTW
MKFRKQIQESEHIKVENSEGGSKLTILAARQEHCGCYTLVVENKLGSRQAQVNLTVVDKP
DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSVEIWDSVDKAWKELATCRSTSFNV
QDLLPDRDYKFRVRAINVYGTSEPSQESELTAVGEKPEEPKDEVEVSDDDEKEPEVEYRT
VTVSTDRKVSDVYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKENIREEIS
IMNCLHHRKLVQCVDAFEDKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISE
GVEYIHKQGIVHLDLKPENIMCVNKTGTKIKLIDFGLARRLENAGSLKVLFGTPEFVAPE
VINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDD
AKDFISNLLKKDMKSRLNCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNA
VRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEGDVSQAFLEAVAEEKPHVKPYF
SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD
VCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEEEE
NT seq
5898 nt
NT seq
+upstream
nt +downstream
nt
atggctatgggggatgtgaagctggctgcctcaacacacgtttctaaaagctccctgggt
atggatcactcgagagccggccccatgcccctgaccgaggctcctgctttcatttcaccc
ccacggaacctctgcatcaaagaaggagccactgccaagtttgaaggaagggtccgcggt
tacccagagccccgtgtggcatggcacagaaatgggcagcccatcaccagtggaggccgc
ttcctgctggactgtggcatccgagggagtttcagccttgtgatccatgctgtctgtgag
gaggacactggaaagtatacctgcgaagctaccaatggtagtggtgcccggcaggtgaca
gtggagttaacggtggaagggggctttgtgaagaagtatggtcagcttgcctccaaaact
atgggggacagattcatatcccccacagcggagacccgtcctagcatctggggagagtgc
ccaccaaagtttgctaccaagctgggccgtgcagtggtcagagaaggacagatgggacga
ttctcctgcaagatcactggcagaccccaaccacaggtcacctggctcaagggagatgtt
cccctgcagcccagtgcccgtgtgtctatgtgtgagaagaatgggatgcaagttctggaa
atccacaaggtcagccaagatgacgtgggagtgtacacgtgcctggtggcgaacgggtcg
gggaaggcctctatgtcagctgagcttaccatccaaggtttggacaacgccaataggcca
tttttgaggggagtgaaggcagccagttcggatatcaggaaggaagtgaccaatggaatc
acccaggggccgaaactggacagcgtagaaactacagctgaacacagaaactgctccagc
atccagaaaggtggctccccgacctgggccacaggtagtcagcctcagtccccaatggaa
tccaagctggagccatctggggactcaccccgaaagaccctgaggacccccgtcctgcag
aagacttccagcaccatcaccctgcaggccacaaaagtccagctggaacctagagccccg
gtctcaggctccctgctgccttccagagaagagagggagaagccatctgctccccctcca
gccacccttcccacgagaccgtctggcctgggaacccaggaagttgtgaacaaggttgct
actaggaaaatccccatggagagccggagggactcaacattccccaaattcgagagcaaa
ccccaaagtcaggaagtccatgaagatcaaacagtccagttcaggtgtgaggtttcaggg
attccgaagccccaagtgacctggttcctggagggtgctcctgtgaggagacgagaaggc
accatggagatttatgaagacggtgggtcgcattacctctgcttgctgagagcccgggca
agggacagcgggaactacagctgcacagcctccaatgtccgaggccaggtgtcctgtgac
tggacgctccttgtgaaaaaactggccgaggtggaggtggccccctcattgtccagtgtc
ctgaaggactgcaccgtcattgaaggccaggactttgtgctgcagtgctcggtgcagggg
accccagtgccccagatcacgtggctgctaaatgggcagcccatccagtacgcgcgctcc
acctgcgaggctggcgtggctacgctccacatccaggatgcgctgccagaggacaacggc
acctacacctgtctggccgagaaccctctggggcaggtgtcctgcagcgcccaggtcact
gtccatgaaaagaagagtgacgggaagcgcgagttcctcctgcctgcagctgccagcaag
cctgccgcaccccgcttcctgcagggcctctcggacctcagagtcatggatggcagccag
gtcaccatgacagtccaggtgtcagggaacccaccccctgaggtcatctggcttcacaat
gggaatgagatccaggagtcagaggacttccactttgaacacagaggcactcggcacagc
ctctgtatccaggaggtgtttccggaggacacgggcacttacacctgtgaggcctggaac
agcgctggggaggttcgcacccaggctgtgctcacggtgcaagagcctcaggatggcacc
cagccctggttcatcagcaagcctcgatcggtgactgcctccctgggccagagtgtgctc
atctcctgtgccatagctggtgacccctttcccaccgtgcactggctccgagacggcaaa
gtcctgtccggagacactggccactttgaggtgctacagaatgaggacgtgttcaccctg
gtcctgaagaacgtgcagccctggcacgctggccagtatgaaatcctgctcaagaaccag
gttggcgaatgcagttgccaggtgtcactgatgctacagagcagccctacccgagccccg
ccacgggggagggtgcctgccagctgtgagggcctctgcggccaaggagctggtgccgat
ggtggtgatggtgattgctacgggaccctgaggcctagctggccagcaggagggcagggt
tggccagaggaggaagacggtgaaggcgtgcggggggtgctgaagaggcgtgtggagacc
cggcagcacacggaggaggccatccgccagcaggaggtggagcagctggactttcgtgac
ctcctggggaagaaggtgagtaccaagaccctatcagaagaagagctgaaggagattcca
gctgagcagatggatttccgtgccaacctacagcggcaagtgaagccaaagatggtgtct
gaggaagagaggaaggtgcacagcccccagcaggtagacttccgctctgtcttggccaag
aaagggactcccaagaccccagtgcctgagaaggttccacctgcaaaacctgccaccccg
gattttcgctcagtgctgggcagcaagaaaaaattaccagcagagaatggtagcaacagt
gctgaggccttgaatgccaaggtggcagaaagtcccaagtccatgggcaatgccaagccc
agtgagccccccaaacccttgggcaatgccaaaccagccgataccctgaaatctgtgggt
aataccaaaccagctgagaccctgaaacctgtgggcaacaccaagccagctgagacccca
aaacctgtgggcaatgccaaaccagctgagaccctgaaacctgtgggcaatgccaaaccg
gtcgagaccccaaaacctgtgggcaacgccaagccggctgagaccctgaaaccggtgggc
aacgccatgccagccgagaccctgaaaccagccgggaaagaagagctcaagaaggaggtt
aagaatgatgtgaactgcaagagggagcattcaggagccacagataatgaaaagagacca
gagagccgagggacagccccagccttcacggagaaactacaagatgtccatgtggcagag
ggcgagaagctgctactccagtgccaggtgtcctctgaccccccagccaccatcacctgg
acgctgaatgggaaggtgctcaagactaccaagttcatcatcctctcccaagaaggttct
ctgtgctccgtgtccatcgagaaggcactgccagaggacagaggcttatacaagtgtgtg
gccaagaatgacgccggccaggctgagtgctcctgccaagtcactatggatgatgctcct
gccagtgagaatgccaaggcccctgagatgaaggcccggaggcccaagagctctcttcct
cctgtgctaggaacagagagtgacgcaactgtgaaaaagaaacctacccccaagacacct
ctgaaagcagccatgccccctcagatcgttcagtttcccgaggaccaaaaggtgcgtgct
ggagagtccgtggagctgcttggtaaggtgacaggcacccagcctatcacctgcacctgg
atgaagttccgaaagcagatccaggaaagcgagcacatcaaggtggagaacagcgagggc
ggcagcaagctcaccatcctggccgcgcgccaggagcactgcggctgctacacactggtg
gtggagaacaagctgggcagcaggcaggcccaggtcaacctgaccgtggtcgacaagcca
gaccccccggccggcacgccttgtgcctctgatatccgaagctcctcactgaccctgtcc
tggtatggctcctcgtacgacgggggcagtgccgtgcagtcctacagtgtcgagatctgg
gactccgtggacaaggcatggaaggaactcgccacctgccgcagcacctcgttcaacgtc
caggacctgctgcccgaccgagactacaagttccgcgtgcgcgcaatcaacgtgtacgga
accagcgagccgagccaggagtcggagctcacagcggtgggagagaaacccgaggagccg
aaggacgaagtggaggtgtcagatgatgatgagaaggagcccgaagtcgagtaccggacg
gtgacagtcagtaccgaccgaaaggtgtccgacgtctacgacatcgaagagagactagga
tctgggaaatttggacaggtctttcgacttgtggaaaagaaaactggaaaaatctgggca
gggaaattcttcaaggcatattcagcaaaagagaaagagaatattcgtgaggagatcagc
atcatgaactgcctccatcaccgcaagctggtccagtgtgtggatgcgtttgaagacaag
gccaacatcgtcatggtcctggagatcgtgtcgggaggtgagctgttcgagcgcatcatc
gatgaggactttgagctgacagagcgagagtgcatcaagtacatgaggcagatctcggag
ggggtggagtacatccacaagcagggcattgtccacctggacctcaagcccgagaacatc
atgtgtgtcaacaagacaggcaccaagatcaagctcatcgacttcggtttggccagaagg
ctggagaatgcagggtctctgaaggtcctctttggcaccccggagtttgtggcacctgaa
gtgatcaactatgagcccattggctatgcaacggacatgtggagcatcggggtcatctgc
tacatcctggtcagtggactttcccccttcatgggtgacaacgataatgaaaccttagcc
aacgttacctctgcaacctgggacttcgatgatgaggcattcgatgagatctccgatgat
gccaaagattttatcagcaacttgctgaagaaagacatgaaaagccgcctgaactgcacc
cagtgccttcagcatccatggctgatgaaagacaccaagaacatggaggccaagaagctc
tccaaggaccgaatgaaaaagtacatggcaagaaggaaatggcagaaaacaggcaatgct
gtgagagccatcggaagactgtcctctatggcaatgatctcagggctcagtggcaggaag
tcctcaacagggtcaccaaccagccctctcaatgcagaaaaactagaatcagaaggagat
gtctcccaagctttcctggaggctgttgctgaggaaaagccccacgtgaaaccctatttc
tccaagacaattcgtgatttagaagttgtggagggaagcgctgctagatttgactgcaag
attgaaggatacccagaccccgaggttgtctggttcaaagacgaccagtccatcagggag
tcccgccacttccagatagactacgatgaggatggaaactgttctttaatcattagcgat
gtgtgtggggatgacgatgccaagtacacctgcaaggctgtcaacagtcttggagaagcc
acctgcacagcggaactcattgtggaaaccatggaggaaggagaaggggaaggggaagag
gaagaagaggaagagtga
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integrated database retrieval system
