KEGG   Phyllostomus discolor (pale spear-nosed bat): 114492422
Entry
114492422         CDS       T07739                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01522  Endocrine resistance
pdic04010  MAPK signaling pathway
pdic04012  ErbB signaling pathway
pdic04014  Ras signaling pathway
pdic04024  cAMP signaling pathway
pdic04068  FoxO signaling pathway
pdic04071  Sphingolipid signaling pathway
pdic04137  Mitophagy - animal
pdic04140  Autophagy - animal
pdic04141  Protein processing in endoplasmic reticulum
pdic04210  Apoptosis
pdic04215  Apoptosis - multiple species
pdic04217  Necroptosis
pdic04310  Wnt signaling pathway
pdic04380  Osteoclast differentiation
pdic04510  Focal adhesion
pdic04530  Tight junction
pdic04620  Toll-like receptor signaling pathway
pdic04621  NOD-like receptor signaling pathway
pdic04622  RIG-I-like receptor signaling pathway
pdic04625  C-type lectin receptor signaling pathway
pdic04657  IL-17 signaling pathway
pdic04658  Th1 and Th2 cell differentiation
pdic04659  Th17 cell differentiation
pdic04660  T cell receptor signaling pathway
pdic04664  Fc epsilon RI signaling pathway
pdic04668  TNF signaling pathway
pdic04722  Neurotrophin signaling pathway
pdic04723  Retrograde endocannabinoid signaling
pdic04728  Dopaminergic synapse
pdic04750  Inflammatory mediator regulation of TRP channels
pdic04910  Insulin signaling pathway
pdic04912  GnRH signaling pathway
pdic04914  Progesterone-mediated oocyte maturation
pdic04917  Prolactin signaling pathway
pdic04920  Adipocytokine signaling pathway
pdic04926  Relaxin signaling pathway
pdic04930  Type II diabetes mellitus
pdic04931  Insulin resistance
pdic04932  Non-alcoholic fatty liver disease
pdic04933  AGE-RAGE signaling pathway in diabetic complications
pdic04935  Growth hormone synthesis, secretion and action
pdic04936  Alcoholic liver disease
pdic05010  Alzheimer disease
pdic05012  Parkinson disease
pdic05016  Huntington disease
pdic05017  Spinocerebellar ataxia
pdic05020  Prion disease
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05132  Salmonella infection
pdic05133  Pertussis
pdic05135  Yersinia infection
pdic05142  Chagas disease
pdic05145  Toxoplasmosis
pdic05152  Tuberculosis
pdic05161  Hepatitis B
pdic05162  Measles
pdic05166  Human T-cell leukemia virus 1 infection
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05169  Epstein-Barr virus infection
pdic05170  Human immunodeficiency virus 1 infection
pdic05171  Coronavirus disease - COVID-19
pdic05200  Pathways in cancer
pdic05208  Chemical carcinogenesis - reactive oxygen species
pdic05210  Colorectal cancer
pdic05212  Pancreatic cancer
pdic05231  Choline metabolism in cancer
pdic05415  Diabetic cardiomyopathy
pdic05417  Lipid and atherosclerosis
pdic05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    114492422 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114492422 (MAPK10)
   04012 ErbB signaling pathway
    114492422 (MAPK10)
   04014 Ras signaling pathway
    114492422 (MAPK10)
   04310 Wnt signaling pathway
    114492422 (MAPK10)
   04668 TNF signaling pathway
    114492422 (MAPK10)
   04068 FoxO signaling pathway
    114492422 (MAPK10)
   04071 Sphingolipid signaling pathway
    114492422 (MAPK10)
   04024 cAMP signaling pathway
    114492422 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114492422 (MAPK10)
   04137 Mitophagy - animal
    114492422 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    114492422 (MAPK10)
   04215 Apoptosis - multiple species
    114492422 (MAPK10)
   04217 Necroptosis
    114492422 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114492422 (MAPK10)
   04530 Tight junction
    114492422 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114492422 (MAPK10)
   04621 NOD-like receptor signaling pathway
    114492422 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    114492422 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    114492422 (MAPK10)
   04660 T cell receptor signaling pathway
    114492422 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    114492422 (MAPK10)
   04659 Th17 cell differentiation
    114492422 (MAPK10)
   04657 IL-17 signaling pathway
    114492422 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    114492422 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    114492422 (MAPK10)
   04920 Adipocytokine signaling pathway
    114492422 (MAPK10)
   04912 GnRH signaling pathway
    114492422 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    114492422 (MAPK10)
   04917 Prolactin signaling pathway
    114492422 (MAPK10)
   04926 Relaxin signaling pathway
    114492422 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    114492422 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    114492422 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    114492422 (MAPK10)
   04722 Neurotrophin signaling pathway
    114492422 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114492422 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114492422 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114492422 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    114492422 (MAPK10)
   05231 Choline metabolism in cancer
    114492422 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    114492422 (MAPK10)
   05212 Pancreatic cancer
    114492422 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114492422 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    114492422 (MAPK10)
   05161 Hepatitis B
    114492422 (MAPK10)
   05171 Coronavirus disease - COVID-19
    114492422 (MAPK10)
   05162 Measles
    114492422 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114492422 (MAPK10)
   05169 Epstein-Barr virus infection
    114492422 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114492422 (MAPK10)
   05135 Yersinia infection
    114492422 (MAPK10)
   05133 Pertussis
    114492422 (MAPK10)
   05152 Tuberculosis
    114492422 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114492422 (MAPK10)
   05142 Chagas disease
    114492422 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114492422 (MAPK10)
   05012 Parkinson disease
    114492422 (MAPK10)
   05016 Huntington disease
    114492422 (MAPK10)
   05017 Spinocerebellar ataxia
    114492422 (MAPK10)
   05020 Prion disease
    114492422 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    114492422 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114492422 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    114492422 (MAPK10)
   05415 Diabetic cardiomyopathy
    114492422 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    114492422 (MAPK10)
   04936 Alcoholic liver disease
    114492422 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    114492422 (MAPK10)
   04931 Insulin resistance
    114492422 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    114492422 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114492422 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114492422 (MAPK10)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     114492422 (MAPK10)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   114492422 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 114492422
NCBI-ProteinID: XP_028362496
UniProt: A0A6J2L4V3
LinkDB
Position
1:102028290..102340559
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAALDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttactatactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggatttgacaaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctacagcgtggaagtaggagactcaaccttcacagtt
ctcaagcgctaccagaatctaaaacctattggctccggggctcagggaatagtttgtgct
gcatatgatgctgcccttgacagaaatgtggccatcaagaagctcagcagaccatttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaatattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgaacggatgtcttaccttctataccaaatgttgtgtggcatcaagcacctt
cattctgctggaattattcacagggatctaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaattctcgactttggactggccaggaccgcaggcacaagcttcatgatg
actccttatgtggtgacacgttattacagagcccctgaggtcatcctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaagtaattgagcaactagga
acaccatgtccagaattcatgaagaaattgcagcccacagtaagaaactatgtggagaat
cggcctaagtatgcaggactcaccttccccaagctctttccagattccctctttcctgct
gattctgagcacaataaactcaaagccagccaagccagggacttattgtcaaagatgcta
gtgattgaccctgccaagaggatatcagtggatgatgccttacagcatccgtacatcaat
gtttggtacgaccctgctgaagtggaggcgcctccacctcagatatatgacaaacagttg
gatgaaagagaacacaccattgaagaatggaaagaacttatatacaaggaagtaatgaac
tcagaagaaaaaactaaaaatggtgtcgtaaaaggacagccctctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga

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