Phyllostomus discolor (pale spear-nosed bat): 114493440
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Entry
114493440 CDS
T07739
Symbol
SOS2
Name
(RefSeq) LOW QUALITY PROTEIN: son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521
EGFR tyrosine kinase inhibitor resistance
pdic01522
Endocrine resistance
pdic04010
MAPK signaling pathway
pdic04012
ErbB signaling pathway
pdic04014
Ras signaling pathway
pdic04062
Chemokine signaling pathway
pdic04068
FoxO signaling pathway
pdic04072
Phospholipase D signaling pathway
pdic04150
mTOR signaling pathway
pdic04151
PI3K-Akt signaling pathway
pdic04510
Focal adhesion
pdic04540
Gap junction
pdic04630
JAK-STAT signaling pathway
pdic04650
Natural killer cell mediated cytotoxicity
pdic04660
T cell receptor signaling pathway
pdic04662
B cell receptor signaling pathway
pdic04664
Fc epsilon RI signaling pathway
pdic04714
Thermogenesis
pdic04722
Neurotrophin signaling pathway
pdic04810
Regulation of actin cytoskeleton
pdic04910
Insulin signaling pathway
pdic04912
GnRH signaling pathway
pdic04915
Estrogen signaling pathway
pdic04917
Prolactin signaling pathway
pdic04926
Relaxin signaling pathway
pdic04935
Growth hormone synthesis, secretion and action
pdic05034
Alcoholism
pdic05160
Hepatitis C
pdic05161
Hepatitis B
pdic05163
Human cytomegalovirus infection
pdic05165
Human papillomavirus infection
pdic05200
Pathways in cancer
pdic05205
Proteoglycans in cancer
pdic05206
MicroRNAs in cancer
pdic05207
Chemical carcinogenesis - receptor activation
pdic05208
Chemical carcinogenesis - reactive oxygen species
pdic05210
Colorectal cancer
pdic05211
Renal cell carcinoma
pdic05213
Endometrial cancer
pdic05214
Glioma
pdic05215
Prostate cancer
pdic05220
Chronic myeloid leukemia
pdic05221
Acute myeloid leukemia
pdic05223
Non-small cell lung cancer
pdic05224
Breast cancer
pdic05225
Hepatocellular carcinoma
pdic05226
Gastric cancer
pdic05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114493440 (SOS2)
04012 ErbB signaling pathway
114493440 (SOS2)
04014 Ras signaling pathway
114493440 (SOS2)
04630 JAK-STAT signaling pathway
114493440 (SOS2)
04068 FoxO signaling pathway
114493440 (SOS2)
04072 Phospholipase D signaling pathway
114493440 (SOS2)
04151 PI3K-Akt signaling pathway
114493440 (SOS2)
04150 mTOR signaling pathway
114493440 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
114493440 (SOS2)
04540 Gap junction
114493440 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
114493440 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
114493440 (SOS2)
04660 T cell receptor signaling pathway
114493440 (SOS2)
04662 B cell receptor signaling pathway
114493440 (SOS2)
04664 Fc epsilon RI signaling pathway
114493440 (SOS2)
04062 Chemokine signaling pathway
114493440 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
114493440 (SOS2)
04912 GnRH signaling pathway
114493440 (SOS2)
04915 Estrogen signaling pathway
114493440 (SOS2)
04917 Prolactin signaling pathway
114493440 (SOS2)
04926 Relaxin signaling pathway
114493440 (SOS2)
04935 Growth hormone synthesis, secretion and action
114493440 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
114493440 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
114493440 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114493440 (SOS2)
05206 MicroRNAs in cancer
114493440 (SOS2)
05205 Proteoglycans in cancer
114493440 (SOS2)
05207 Chemical carcinogenesis - receptor activation
114493440 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
114493440 (SOS2)
05231 Choline metabolism in cancer
114493440 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
114493440 (SOS2)
05225 Hepatocellular carcinoma
114493440 (SOS2)
05226 Gastric cancer
114493440 (SOS2)
05214 Glioma
114493440 (SOS2)
05221 Acute myeloid leukemia
114493440 (SOS2)
05220 Chronic myeloid leukemia
114493440 (SOS2)
05211 Renal cell carcinoma
114493440 (SOS2)
05215 Prostate cancer
114493440 (SOS2)
05213 Endometrial cancer
114493440 (SOS2)
05224 Breast cancer
114493440 (SOS2)
05223 Non-small cell lung cancer
114493440 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
114493440 (SOS2)
05160 Hepatitis C
114493440 (SOS2)
05163 Human cytomegalovirus infection
114493440 (SOS2)
05165 Human papillomavirus infection
114493440 (SOS2)
09165 Substance dependence
05034 Alcoholism
114493440 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114493440 (SOS2)
01522 Endocrine resistance
114493440 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
RHG20_PH
PH_19
Motif
Other DBs
NCBI-GeneID:
114493440
NCBI-ProteinID:
XP_028364119
UniProt:
A0A6J2LAM4
LinkDB
All DBs
Position
1:complement(178295093..178398559)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMGRPAVAQYFQSIADGFREAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEXIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFIMRKTQICDKEDSCEYKHAFELISKDENSVIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
AEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNNDFXKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEIRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPNSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNLKSDDDPPAIPPRQPPPPKIKPRVPAPTGAFDGPL
LSPPPPPPRDPLPDSPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYVLNSSHSNVVHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgaggaaggttcaggagcaagtacatcccaatctctcggct
aatgaagaatctctctattatattgaagagctgatttttcagctacttaataaattatgc
atggcccaaccaaggactgttcaagatgtagaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctatagctgatgcacagtcggccatagagaaacgaaaacgaaga
aatcctctcttattgcctgtggacaaaatccatccttcactgaaggaagttttagggtac
aaagtggactaccatgtgtccttatatattgtggctgtactagagtatatctcagctgat
attttgaaattagctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gacattaaagtatcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaacctagttcttcaggtgaattaaactattac
gaccttgtcagaactgaaattgcagaagaaagacagtatctgcgggaactaaatatgatc
ataaaagtgttccgagaagcctttctttctgacaaaaagctgttcaaatcttctgacatt
gagaagattttcagtaatatctcagatatacatgagttgacagtaaaacttttagggttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccaaaatttaatgaacatttcagtaagttgatgggcagacctgcagtggctcaa
tactttcagtccattgctgatggttttagagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtgtatcactgttggcactattttgaattgttaaagcaattgaaagca
tgtagtgaagaacaagaggacagagaatgtttaaatcaagcaattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcaatattcacctcgacgccgacctggggat
cctgtctgccctttttataaccgtcagttaagaagcaagcacttggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaanttattatggaaggtccattgacaagaattggtgctaaacatgaacggcatattttc
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccaggt
tatagtagtgcagaatacagattaaaagaaaaattcatcatgagaaaaacacaaatatgt
gataaagaagatagttgtgagtacaaacatgcatttgaattgatatccaaagatgaaaac
agcgtaatatttgctgctaagtctgcggaagagaaaaataactggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgttagattcagtattattgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaacggtggtgaagttaattgaaagactgacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaactgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gcagagaaaggcgaacagccaattagtgcagaccttaaaagatttcgcaaggaatatgtc
caaccagtacaacttaggatcctaaatgtatttcggcactgggttgaacaccatttctat
gactttgaaagagatctggagttgcttgaaaggctagaatccttcatttcaagtgtaaga
gggaaagccatgaagaaatgggtagagtccattgctaagatcatcaagagaaagaaacaa
gctcaggcaaatggaataagtcataatattacctttgaaagtccccctccaccaattgaa
tggcatatcagcaaaccaggacaatttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccctct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgtcatactacaaatcttacactttggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtagcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca
gtatatagactagatcacacctttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaggatcactttaaaaaatacctagcaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttnttaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtggctgaaattactggagaaattcagcaatatcagaatcaaccttactgtttacgg
atagaaccagaaataaggcggttctttgaaaaccttaatcccatgggaagtgcttctgaa
aaagagtttacagattacttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcccaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggcactttaagaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagcttgaatcaacagtg
tcggcaccaacctctccaaatacaccgtctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca
gttctcttgccaaattcaaaatctttcttcagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatctgaaatctgatgatgaccctcctgctattccaccaagacaacct
cctcctccaaagataaaacccagagttcctgctcctactggtgcatttgatgggccactg
cttagtccaccgccgccaccgccaagagatcctcttcctgatagccctccaccagttccc
cttcggcctccggaacactttataaactgtccatttaatcttcaaccgcctccactggga
catcttcacagagatccagactggttcagagacgttagcacttgtccaaattcgccaaac
actcctcctagtacaccctctccaagggtaccacgtcgatgctatgtgctcaattctagt
cacagtaatgttgttcatccccaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttataaacgggagctttcacaccccccattgtat
agactgcctttgctagaaaacgcagaaactcctcaatga
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