Phyllostomus discolor (pale spear-nosed bat): 114494165
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Entry
114494165 CDS
T07739
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00190
Oxidative phosphorylation
pdic01100
Metabolic pathways
pdic04714
Thermogenesis
pdic04723
Retrograde endocannabinoid signaling
pdic04932
Non-alcoholic fatty liver disease
pdic05010
Alzheimer disease
pdic05012
Parkinson disease
pdic05014
Amyotrophic lateral sclerosis
pdic05016
Huntington disease
pdic05020
Prion disease
pdic05022
Pathways of neurodegeneration - multiple diseases
pdic05208
Chemical carcinogenesis - reactive oxygen species
pdic05415
Diabetic cardiomyopathy
Module
pdic_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
114494165 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
114494165 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
114494165 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
114494165 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
114494165 (NDUFS1)
05012 Parkinson disease
114494165 (NDUFS1)
05014 Amyotrophic lateral sclerosis
114494165 (NDUFS1)
05016 Huntington disease
114494165 (NDUFS1)
05020 Prion disease
114494165 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
114494165 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
114494165 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
114494165 (NDUFS1)
Enzymes [BR:
pdic01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
114494165 (NDUFS1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
114494165
NCBI-ProteinID:
XP_028364859
UniProt:
A0A6J2LCP5
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Position
4:24123386..24152756
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AA seq
727 aa
AA seq
DB search
MLRVPVRRALAGLAKSPKEYVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYVEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNELKVALIGSQVDLTYRYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKVRTSSGVAGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaagggtacctgtaagaagggccttagcaggccttgctaaatctcctaaagaatat
gttcggacaactgccacagcagcaagcaacctgattgaagtatttgttgatggtcagtct
gtcatggtggagccgggaactactgtccttcaggcttgtgaaaaggttggcatgcagatc
cctcgattctgttatcatgaaaggttgtcagttgctggaaactgcaggatgtgccttgtt
gaaatcgagaaagctcccaaggttgtagctgcctgtgccatgccagtaatgaaaggttgg
aatatcctgacaaactcagagaaaactaagaaagccagagaaggtgtgatggagttctta
ttagcaaatcacccactggactgtcctatctgtgatcagggaggcgaatgtgatctgcag
gaccagtccatgatgtttggaagtgataggagccgatttttagaggggaaacgtgctgta
gaggacaagaacattgggccattggtcaagaccatcatgactagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggcacaacaggcaga
ggaaatgacatgcaagttggcacatatgttgaaaagatgtttatgtccgaactgtctggg
aatatcattgatatctgtcctgtgggtgccctgacctctaagccctatgcctttactgcc
cggccttgggaaacaagaaagactgaatccattgatgtcatggatgcagttggaagcaat
attgtggtaagcacaagaactggggaggtgatgaggattctgccaagaatgcatgaggac
atcaatgaagagtggatctctgacaaaaccagatttgcctacgatgggctgaaacgtcaa
aggcttaccgagccgatggtcagaaacgaaaaggggcttttaacctacacctcctgggag
gatgcgctctctcgtgtagctggaatgttgcagagttttcaaggcaaggatgtggcagca
atcgcaggtggtttggtggatgccgaagccctagtagctctcaaagatttgcttaataga
gtggactctgacaccctgtgcaccgaagaggtcttccccactgcaggggctggtacagat
ttgcgttccaattatcttcttaatactacaattgctggtgtggaagaggcagatgttgtc
cttctggttggtacaaatccacgttttgaggcaccactgtttaatgctagaattcggaag
agctggcttcataatgagttaaaagtggcccttataggcagccaagtggatctcacttac
agatatgaccatctgggagattccccaaaaattcttcaagacattgcttccggtagccat
ccattcagccaggtcctaaaggaagctaaaaaacctatggtggttttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtctccagcattgctcagaaggtt
cggacaagcagtggcgttgctggtgactggaaggttatgaatatcctccacaggattgca
agccaagtagctgctttagatcttggctataaacctggggtggaagcaattcgaaagaac
cctcccaaagtgctctttctcctaggagcagatggaggttgtatcactcgacaggacttg
ccaaaggattgtttcattatttatcaaggccatcatggtgatgtcggagctcctatagct
gatgttattctccccggcgctgcttacacagagaagtctgctacttatgtcaatactgag
ggccgagctcagcagactaaagtagcagtgacacctcccggcttggcaagagaagactgg
aaaattataagagccctctcggagattgcaggtataactcttccatatgatactctggat
caagtaaggaacagattggaagaagtctctcctaatcttgttcgatatgatgacgttgaa
ggagctaattatttccagcaagcaagcgagctctccaagctagtgaaccagcaacttctt
gctgatccccttgtgccccctcagctgacaataaaagacttctacatgacagattcgatc
agcagagcctcacagacaatggccaaatgtgttaaagccgtcacggagggcgcccaggca
gtggaggagccatccatatgctga
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