Phyllostomus discolor (pale spear-nosed bat): 114498103
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Entry
114498103 CDS
T07739
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521
EGFR tyrosine kinase inhibitor resistance
pdic04151
PI3K-Akt signaling pathway
pdic04217
Necroptosis
pdic04380
Osteoclast differentiation
pdic04550
Signaling pathways regulating pluripotency of stem cells
pdic04620
Toll-like receptor signaling pathway
pdic04621
NOD-like receptor signaling pathway
pdic04630
JAK-STAT signaling pathway
pdic04658
Th1 and Th2 cell differentiation
pdic04659
Th17 cell differentiation
pdic05140
Leishmaniasis
pdic05145
Toxoplasmosis
pdic05152
Tuberculosis
pdic05160
Hepatitis C
pdic05161
Hepatitis B
pdic05162
Measles
pdic05163
Human cytomegalovirus infection
pdic05164
Influenza A
pdic05165
Human papillomavirus infection
pdic05166
Human T-cell leukemia virus 1 infection
pdic05167
Kaposi sarcoma-associated herpesvirus infection
pdic05168
Herpes simplex virus 1 infection
pdic05169
Epstein-Barr virus infection
pdic05171
Coronavirus disease
pdic05200
Pathways in cancer
pdic05203
Viral carcinogenesis
pdic05212
Pancreatic cancer
pdic05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
114498103 (JAK1)
04151 PI3K-Akt signaling pathway
114498103 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
114498103 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
114498103 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
114498103 (JAK1)
04621 NOD-like receptor signaling pathway
114498103 (JAK1)
04658 Th1 and Th2 cell differentiation
114498103 (JAK1)
04659 Th17 cell differentiation
114498103 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
114498103 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114498103 (JAK1)
05203 Viral carcinogenesis
114498103 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
114498103 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
114498103 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
114498103 (JAK1)
05161 Hepatitis B
114498103 (JAK1)
05160 Hepatitis C
114498103 (JAK1)
05171 Coronavirus disease
114498103 (JAK1)
05164 Influenza A
114498103 (JAK1)
05162 Measles
114498103 (JAK1)
05168 Herpes simplex virus 1 infection
114498103 (JAK1)
05163 Human cytomegalovirus infection
114498103 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
114498103 (JAK1)
05169 Epstein-Barr virus infection
114498103 (JAK1)
05165 Human papillomavirus infection
114498103 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
114498103 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
114498103 (JAK1)
05140 Leishmaniasis
114498103 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114498103 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pdic01001
]
114498103 (JAK1)
Enzymes [BR:
pdic01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114498103 (JAK1)
Protein kinases [BR:
pdic01001
]
Non-receptor tyrosine kinases
JAK family [OT]
114498103 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
114498103
NCBI-ProteinID:
XP_028369989
UniProt:
A0A6J2LSK1
LinkDB
All DBs
Position
5:complement(47422057..47545355)
Genome browser
AA seq
1152 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNQEAPEPGVEVLFYLSDREPLQLGNGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNHTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIRE
EWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH
YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC
FEKPEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGELMSHLKKQILRTDNISFVLKR
CCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGTL
VDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE
NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL
AREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT
LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM
RDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG
EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG
SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF
GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDS
SPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTTF
QNLIEGFEALLK
NT seq
3459 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgcgg
agctccaagaagaccgaggtgaatcaggaggcccctgagccaggggtggaagtgcttttc
tacctgtcagacagggagcccctccagctgggcaacggagagtacacggcggaggagctg
tgcatcagggcggcacaggagtgctgtatctctcctctgtgtcacaacctctttgctctg
tatgatgagaacaccaagctctggtatgctccaaatcacaccatcactgtcgatgacaag
acatcgctccggctccattaccggatgaggttttattttaccaactggcatgggaccaat
gataatgagcagtcggtatggcgacattctccaaagaagcagaaaaatggctacgagaaa
aaaaaagttcctgatgcaacccctctccttgacgccagctctctggaatatctgtttgct
cagggacagtacgatttggtcaaatgcctggctcccattcgagacccgaagactgagcag
gatggccacgacatcgagaacgagtgtctgggcatggccgtcctggccatctcccactat
gccatgatgaagaagatgcagctgccagaactccccaaggatatcagctacaagcgatat
attccagaaacgctgaataagtccatcagacagaggaaccttcttaccaggatgcggata
aataatgttttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc
gtgtccacacatgacctgaaggtgaaatacctggccaccttggaaacgttgacaaaacat
tatggtgctgaaatattcgagacttccatgttactgatttcatcagaaaatgagatgaac
tggtttcacccaaatgacagtgggaatgttctctatgaagtgatggtgactggaaacctt
ggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaactg
aaacggaaaaaactggaaaacaaacacaagaaggatgaggagaaaaacaaaatccgggaa
gagtggaacaatttttcttactttcctgaaatcactcatattgtaatcaaggagtctgtg
gtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgaggaa
gccttgtccttcgtgtctctggtagatggctactttcggctcacagcagacgcccatcat
tacctctgcaccgacgtggctcccccactgatcgtccacaacatacagaatggctgtcac
ggtccaatctgcacagaatatgccatcaataaattacggcaagaaggaagcgaggaggga
atgtatgtgttgcggtggagctgcactgacttcgacaacatcctcatgacggtcacctgc
tttgaaaagcctgaggtgctgggtggccagaaacagttcaagaatttccagatcgaggtg
cagaagggtcgctacagcctgcatggctcagaccgcagtttccccagcctgggggaactc
atgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaagcgc
tgctgccagcccaagccccgagaaatctccaatctgctggtggctaccaagaaagcccag
gagtggcagcctgtctaccccatgagtcagctgagtttcgataggatcctcaagaaagac
attatgcaaggtgagcaccttgggagaggcacacggacgcacatctactctgggaccctg
gtggattacaaggacgacgaaggaacttctgaggagaagaaaataaaagtgatcctcaaa
gtcttagaccctagccacagggacatttctctggccttcttcgaggcagccagcatgatg
cgacaggtctcccacaaacacatcgtgtacctctacggcgtctgtgtccgggacgtggag
aatatcatggtggaagagtttgtggaaggagggcctctagatctcttcatgcaccggaaa
agcgatgtccttaccacaccgtggaaattcaaagttgctaaacagctggctagtgccctg
agttacctggaggataaagacctggtccatggaaacgtgtgcactaaaaacctcctcctg
gcccgagagggcattgacagtgagtgcggccccttcatcaagctcagcgaccccggcatc
cccatcactgtgctgtccaggcaagaatgcatagaacgaatcccatggattgctcccgag
tgtgttgaagactccaagaacctgagcgtggctgctgacaaatggagctttggaaccaca
ctctgggaaatctgctacaatggcgagatccccctgaaagacaagactctgattgagaaa
gagagattctacgaaagccggtgccgaccagtgacaccatcttgtaaggagctggctgac
cttatgacccgctgcatgaactatgaccccaatcagaggcccttcttccgagccatcatg
agagacatcaacaagctggaagagcagaatccagacattgtttcagaaaaaaagccagca
accgaggtggatcccacacatttcgaaaagcggttcttaaagaggatccgtgacttggga
gagggccactttgggaaggttgaactctgccgctatgaccctgaaggggacaatacaggg
gagcaagtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagccgatctg
aagaaggagatcgaaatcttacggaacctgtaccatgagaacattgtgaagtacaaaggc
atctgcacagaagatggaggaaatggtatcaagctcatcatggaatttctgccttcagga
agccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagttaaaa
tatgccgttcaaatttgtaaggggatggactatttgggttcacgacagtacgtccaccgg
gacttagcagcaagaaatgtccttgttgagagcgagcaccaagtgaaaattggagacttt
ggtttaactaaagcaattgaaaccgacaaggagtactacaccgtcaaggacgaccgggac
agccctgtgttttggtatgctccggagtgtttaattcagtgtaagttctatatcgcctct
gacgtctggtcgttcggagtgactctgcacgagctgcttacgtactgtgactcggactcc
agtcccatggcgttgttcctgaaaatgataggccccactcacggccagatgacagtaaca
agacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtccagat
gaggtttatcaacttatgagaaaatgctgggaattccaaccatctaatcggacaaccttt
cagaacctcattgaaggatttgaagcacttttaaaataa
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integrated database retrieval system
