Phyllostomus discolor (pale spear-nosed bat): 114498755
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Entry
114498755 CDS
T07739
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04270
Vascular smooth muscle contraction
pdic04360
Axon guidance
pdic04611
Platelet activation
pdic04625
C-type lectin receptor signaling pathway
pdic04810
Regulation of actin cytoskeleton
pdic05135
Yersinia infection
pdic05152
Tuberculosis
pdic05163
Human cytomegalovirus infection
pdic05200
Pathways in cancer
pdic05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
114498755 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
114498755 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
114498755 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
114498755 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
114498755 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114498755 (ARHGEF12)
05205 Proteoglycans in cancer
114498755 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
114498755 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
114498755 (ARHGEF12)
05152 Tuberculosis
114498755 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pdic04131
]
114498755 (ARHGEF12)
Membrane trafficking [BR:
pdic04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
114498755 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
PDZ_Tricorn
AAA_23
Motif
Other DBs
NCBI-GeneID:
114498755
NCBI-ProteinID:
XP_035884265
UniProt:
A0A7E6DZU7
LinkDB
All DBs
Position
6:complement(76568958..76789170)
Genome browser
AA seq
1543 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILSRESPTDKKQKVERSESHDFDPADSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSAQIPLSDSEVESLVIGHMSPIVTSPHSPG
TSGNMERITSPVLMEEENNVVHNQKVEILRKMLRKEQERLQLLQEDYNRTPAERLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVITSSKPLGDTLIVSELEADPGNGIGKIDYSSGDVS
WPSSDNANSPKSGLKEKIYLEENLEKSEVIQDTDTQSLIGSPSTHTAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVISQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRYYIQTMQERVHPEIQRHL
EDFRQKRSMGLTLAESELTKLDVERDKDRVTLEKERACAEQIVAKIEEVLMTAQAIEEDK
SSTMQYVIFMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKHTMKKDREGEEKGKRRGFSSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSVPLSVSPEPQDIAKLRQSGLASEGSDIGY
LPANSMSSMASVATLFQEGGKENDTGSKQVGETPVSGDSLDGTPRTSNIIFDFLLPPLDQ
VQEEEWEIERIPEHGTPKPFRKFDSIGFGESQSEDELFENDLETDPPNWQQLVSREVLVG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQLFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNESSVIDQIGEDLLAWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFHTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV
KKAADHCRQILNYVNQSVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDMLVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKAFFVISMSDNGAQIYELVAQTVSEKTVWQDLICQMAASVKEQSIK
PIPLPQSPPCEEDNDEEPPKIKVERHGISVTCLQSTDRDLELESPLISSKAQPHSLNASG
KSEVDDLFVAERQFAKEQHADGTVKEVGVKYPITIPDSHLPVSEGQWALDALRNLGLLKQ
LLVQKLSLTEKSTQEDWPHFSTYRTASPGVQRDSGTQNFEIIKAYHPGERQMPFRTGTGD
ISACYSLRASTESYVPRDSVLLAFQDSQASNILVMDHMIMTPEIPPAEPEGGLDESEEHF
FDAHEVHSDDNPLEGDGAIKMEEKDANLHISGNYLILDGYETVQESSTDEEVTSSLPPQP
MKGLPFVDSTHQPQHSLQNALSDGAVSPFTPEFVVQQCWGAVEHSCYEIQSPSACADSER
QIMEYIHKIEADLEHLKRVEESYTILWQRLAGSALTDNHSDKS
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacgcagtctactatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgagccgagagtcaccaacagataagaagcagaaagttgagcgcagtgaa
tcacatgattttgaccctgcagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcagcgttgtgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtctttgtacagtctgtcaaagaagat
ggagcagccatgcgagctggagtacagacaggtgatcgaatcatcaaggtgaatggaaca
ctggtgactcattcaaatcatttggaggtggtaaagttaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcagcccaaattccactttctgattctgaa
gtagagtcattggtcattggacatatgtctcccattgtgacatcccctcattcacctgga
acatctgggaatatggagagaattactagtcctgtactcatggaggaagaaaacaatgtg
gttcataaccagaaagtagaaatattgagaaaaatgttacggaaagaacaggaacggcta
cagttattacaggaagattacaacagaacacctgccgaaagattgctaaaagagattcaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgcc
caggatggagctgtaattacttcctccaagcctttaggtgacacattaatagtcagtgag
ttagaggcagatcctggtaatggaataggcaaaattgactacagcagtggagatgtttct
tggccgagcagtgacaatgcaaatagtcctaagagtggcctgaaagagaagatttatcta
gaggaaaacctagagaaaagtgaagtaattcaggacactgatactcaatcacttattgga
agtccctcaacccatacagcacctcatattattggagcagaggatgatgattttggtact
gaacatgaacagatcaatgggcagtgcagctgtttccagagcattgaactgctaaaatct
cgccctgctcacttagctgtttttttacatcatgtaatttcacagtttgaccctgcgaca
ttgctttgttatctctattcagacctttataaacagaccaattccaaggagactcgtcgt
gtcttccttgagtttcatcagttcttcctggatcgatctgcacacctgaaagtttctgtt
cctgatgaaatatcggtagatctagagaaaagacgacctgagcttattcctgaggatctg
catcgctactatattcaaactatgcaagaaagagtccacccagaaattcagaggcactta
gaagattttcggcagaaacggagcatggggctgaccttggctgaaagcgaattgactaaa
cttgatgtagagcgagacaaagaccgggtaactttggagaaggaacgggcatgtgcagaa
caaattgttgccaaaattgaagaagtgttgatgactgctcaggctatagaagaagataag
agttcaacaatgcagtatgttattttcatgtacatgaagcatttgggagtaaaagtgaaa
gaacctcgaaatttggagcataaacggggtcggattggattccttccaaaaatcaaacac
actatgaagaaagatagggaaggtgaagagaaagggaagcgcagaggattctccagcatc
ctgggacccccaaggaggccaagccgtcatgacaatagtgcaattggcagagccatggaa
ctacagaagcagcgccaccctaagcatttatctgtacccttatctgtgagtcctgagcct
caggacattgctaagttgcgccagagtgggttagcaagtgaaggatcagacattggatac
ctaccagccaattccatgtcttctatggcttcagtggccactcttttccaggaaggaggg
aaagagaatgatacgggatcaaagcaagttggagaaacaccagtatctggagattccttg
gatggcacacctcgtacttctaatatcatctttgattttctgcttcctccattggatcag
gtgcaagaggaggaatgggaaatagaaaggatacctgaacatgggacaccaaagcccttt
cgaaagtttgacagcataggttttggagaaagtcaaagtgaagatgaactgtttgaaaat
gacctggagacagatccacccaactggcaacagctcgttagtcgagaagtattagtggga
ctaaagccttgtgaaatcaaaagacaggaagtaattaatgaattgttttatactgaaaga
gctcatgttcgaacactaaaggttcttgatcagttgttctatcagcgagtgtccagagaa
ggaattctgtcaccttcagaactacggaaaattttttcaaacttagaagatattcttcaa
cttcacattgggttaaatgagcaaatgaaagctgttcgaaagaggaatgagtcctctgtc
attgaccaaattggggaagatttgctggcctggttcagtggaccaggggaggagaagttg
aaacacgctgctgctaccttttgcagtaaccaaccttttgccctggaaatgatcaaatct
cgtcagaaaaaggattctcgatttcatacttttgtgcaagatgctgagagtaatccactc
tgtcgtcgtctgcagctgaaggatatcattcctacccaaatgcagaggcttactaagtac
cctcttctattggataatattgccaaatacacagagtggccaacggaaagggagaaggtg
aagaaagctgcagatcattgtcgtcagatcttaaattatgtaaatcagtctgtcaaggag
gcagaaaacaagcagcgtttagaagattatcagcgtcgccttgatacttctaatctgaag
ttgtcagagtacccaaatgttgaagagctcaggaatttggatttaacaaaaaggaagatg
attcatgaagggccattggtttggaaggtgaatagagataaaactattgatctatacaca
ttgcttttggaagacatgcttgtattgttacaaaagcaggatgatagactggtgttaagg
tgtcatagtaagattctggcatctacagctgatagcaaacacacatttagccctgtcatt
aagttgaatacagtgttggttcgacaagtggcaacagataacaaagcttttttcgtcatt
tccatgtcagacaatggagcccaaatttatgaactggtggcacagacagtttctgaaaag
actgtctggcaggacctaatctgtcagatggctgcatcagtgaaggagcaatccataaag
ccaattccattgccacagtcaccaccttgcgaagaagacaatgatgaagaacctccaaaa
ataaaagtggaacgtcatggcatttcagtaacttgcctgcagagcacagacagagatttg
gaattagaatctcccttgatatcatcaaaagctcagcctcattcactgaatgcctctggg
aaatcagaggtagatgatctctttgtggctgaaagacaatttgcaaaggaacagcatgca
gatgggactgtaaaggaagttggagtaaaatatcccatcacaattccagattcacacttg
cctgtctcagaaggacagtgggcattggatgcactaaggaatttgggtttgttgaagcag
ttgctggtacagaagctgagtttgactgagaagagcactcaggaagattggccacatttc
tcaacatacagaacagcctccccaggggtacagagagacagtggaacccagaactttgaa
attattaaggcctatcatcctggtgaaagacagatgccctttagaactggaactggtgac
atttcagcttgttacagtctccgggcttcaacagagtcttatgttccacgggattcagtg
ttactggcattccaagatagccaggcaagtaacattttagtaatggaccacatgattatg
accccagagattcctcctgcagagccagaaggaggtcttgatgagagtgaagagcacttt
tttgatgcccatgaagtacatagtgatgataatccattagaaggtgatggagccattaaa
atggaagaaaaggatgccaacttacacatctcaggaaactatttgatccttgatggctac
gaaacagtacaggagagctccacagatgaggaggtcacctcctcccttcctccacaaccc
atgaaaggcctcccctttgtggactctactcaccagccacaacattctctccagaatgct
ctttctgatggtgcagtttcaccattcaccccagaattcgtggtccagcagtgctgggga
gctgtggagcattcctgttatgagatccagagtccctccgcttgtgcagattcagaaaga
cagatcatggagtatattcataagatagaggctgaccttgaacacttaaagagggtggag
gaaagttataccattctttggcaaaggctggctggatcagccctcacagacaaccactca
gataaaagttag
DBGET
integrated database retrieval system
