Phyllostomus discolor (pale spear-nosed bat): 114499241
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Entry
114499241 CDS
T07739
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521
EGFR tyrosine kinase inhibitor resistance
pdic01522
Endocrine resistance
pdic04010
MAPK signaling pathway
pdic04012
ErbB signaling pathway
pdic04014
Ras signaling pathway
pdic04062
Chemokine signaling pathway
pdic04068
FoxO signaling pathway
pdic04072
Phospholipase D signaling pathway
pdic04150
mTOR signaling pathway
pdic04151
PI3K-Akt signaling pathway
pdic04510
Focal adhesion
pdic04540
Gap junction
pdic04630
JAK-STAT signaling pathway
pdic04650
Natural killer cell mediated cytotoxicity
pdic04660
T cell receptor signaling pathway
pdic04662
B cell receptor signaling pathway
pdic04664
Fc epsilon RI signaling pathway
pdic04714
Thermogenesis
pdic04722
Neurotrophin signaling pathway
pdic04810
Regulation of actin cytoskeleton
pdic04910
Insulin signaling pathway
pdic04912
GnRH signaling pathway
pdic04915
Estrogen signaling pathway
pdic04917
Prolactin signaling pathway
pdic04926
Relaxin signaling pathway
pdic04935
Growth hormone synthesis, secretion and action
pdic05034
Alcoholism
pdic05160
Hepatitis C
pdic05161
Hepatitis B
pdic05163
Human cytomegalovirus infection
pdic05165
Human papillomavirus infection
pdic05200
Pathways in cancer
pdic05205
Proteoglycans in cancer
pdic05206
MicroRNAs in cancer
pdic05207
Chemical carcinogenesis - receptor activation
pdic05208
Chemical carcinogenesis - reactive oxygen species
pdic05210
Colorectal cancer
pdic05211
Renal cell carcinoma
pdic05213
Endometrial cancer
pdic05214
Glioma
pdic05215
Prostate cancer
pdic05220
Chronic myeloid leukemia
pdic05221
Acute myeloid leukemia
pdic05223
Non-small cell lung cancer
pdic05224
Breast cancer
pdic05225
Hepatocellular carcinoma
pdic05226
Gastric cancer
pdic05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114499241 (SOS1)
04012 ErbB signaling pathway
114499241 (SOS1)
04014 Ras signaling pathway
114499241 (SOS1)
04630 JAK-STAT signaling pathway
114499241 (SOS1)
04068 FoxO signaling pathway
114499241 (SOS1)
04072 Phospholipase D signaling pathway
114499241 (SOS1)
04151 PI3K-Akt signaling pathway
114499241 (SOS1)
04150 mTOR signaling pathway
114499241 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
114499241 (SOS1)
04540 Gap junction
114499241 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
114499241 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
114499241 (SOS1)
04660 T cell receptor signaling pathway
114499241 (SOS1)
04662 B cell receptor signaling pathway
114499241 (SOS1)
04664 Fc epsilon RI signaling pathway
114499241 (SOS1)
04062 Chemokine signaling pathway
114499241 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
114499241 (SOS1)
04912 GnRH signaling pathway
114499241 (SOS1)
04915 Estrogen signaling pathway
114499241 (SOS1)
04917 Prolactin signaling pathway
114499241 (SOS1)
04926 Relaxin signaling pathway
114499241 (SOS1)
04935 Growth hormone synthesis, secretion and action
114499241 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
114499241 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
114499241 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114499241 (SOS1)
05206 MicroRNAs in cancer
114499241 (SOS1)
05205 Proteoglycans in cancer
114499241 (SOS1)
05207 Chemical carcinogenesis - receptor activation
114499241 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
114499241 (SOS1)
05231 Choline metabolism in cancer
114499241 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
114499241 (SOS1)
05225 Hepatocellular carcinoma
114499241 (SOS1)
05226 Gastric cancer
114499241 (SOS1)
05214 Glioma
114499241 (SOS1)
05221 Acute myeloid leukemia
114499241 (SOS1)
05220 Chronic myeloid leukemia
114499241 (SOS1)
05211 Renal cell carcinoma
114499241 (SOS1)
05215 Prostate cancer
114499241 (SOS1)
05213 Endometrial cancer
114499241 (SOS1)
05224 Breast cancer
114499241 (SOS1)
05223 Non-small cell lung cancer
114499241 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
114499241 (SOS1)
05160 Hepatitis C
114499241 (SOS1)
05163 Human cytomegalovirus infection
114499241 (SOS1)
05165 Human papillomavirus infection
114499241 (SOS1)
09165 Substance dependence
05034 Alcoholism
114499241 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114499241 (SOS1)
01522 Endocrine resistance
114499241 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
114499241
NCBI-ProteinID:
XP_028371033
UniProt:
A0A6J2LYZ7
LinkDB
All DBs
Position
6:complement(23019871..23133979)
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENVSKWRGLLVSALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSVSDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADIYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDTDLLRRMEEFIGT
VRGKAMRKWVESITKIIQRKKMARDSGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSATDVCSVFDSDHSSPFHSSSDTVFIQVTLSHGPRSASVSSISL
TKGTDEAPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSLSDAPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNTFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSMAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccctacgagtttttcagcgaagagaacgtgtccaagtggcgg
gggctgctagtgtcggcgctgaaaaaggtccaggggcaagttcatcctactcttgagtcg
agtgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgtttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaatcgataaatgggcaatagctgatgcccagtcagccattgaaaagaggaaacgaaga
aaccctttgtctctcccagtagaaaaaatccatcctttactaaaggaggtcctaggttat
aaaattgaccatcaggtttctgtttacatagtagcagtattagaatatatttctgcagac
attttaaagctggtgggtaattatgtacgaaatatacggcactatgaaattacaaaacaa
gatattaaagtagcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatcgttaactgatgaagaaccttccacctcaggagagcaaact
tactatgatttggtaaaggcatttatggcagaaattcgacaatacataagggaactaaat
ttaattataaaagtttttagagaaccctttgtctccaactcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtgaagttactg
ggccacatagaagatactgtagaaatgacagatgaaggcagtccccacccactagtagga
agctgctttgaagatttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgtcctggttttcatgatcatttccttagtcagttatccaagcctggagca
gcactttatttgcagtcaataggcgaaggcttcaaagaagcagttcaatacgttttaccc
aggctgcttctagccccagtttaccattgtctacattactttgagcttttaaagcagtta
gaagagaagagtgaagatcaagaagataaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactt
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaatgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacacgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggagctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ctgatatctttgcagtaccggagcacactggaaaggatgcttgatgtgacgatgctgcag
gaagagaaggaggagcagatgaggctccctagtgctgacatttatagatttgcagagcct
gactctgaagagaatataatatttgaagaaaatatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaactcatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttctaatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagagctaaaaaggtttagaaaagaa
tatatacagcctgtacaactgcgagtattgaatgtctgccggcactgggtagaacaccac
ttctatgactttgaaagagatacagatcttttgcggcgaatggaggagtttattggaaca
gtaagaggtaaagcaatgagaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaatggcaagagacagtggaccaggtcataatattacatttcagagttcacctcccaca
gtcgaatggcatataagcagacctggacacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcggcagctcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtggctgtggtgagtcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggcgtccttgaggtggtcagtgctatgaactca
tcacccgtttacaggctggaccacacatttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattaagtgaagatcattataagaagtacttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttacctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaattttagcaaa
aggagaaaagtggcagaaataacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaaacctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
agaaaaattagttacagcaggatacctgaaagtgagacagaaagcaccgcatctgcacca
aactcgccaagaacaccgctaacacctcctcctgcttctggtgcttctagtgccacagac
gtttgcagtgtatttgattctgaccattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgtcccatggcccaagatctgcttcagtgtcatctataagttta
accaaaggcactgatgaagcgccagtcccccctcctgttcctccacggagacggccagaa
tctgcccccgcagaatcttcaccatctaagattatgtctaagcacttggacagcccccca
gcaatccctcctaggcagcccacatcaaaagcctactcgccacgatactcaatatcagac
cggacctctctgtcagacgctcctgaaagcccccccttacttccgccgcgagaacctgtg
aggacgcctgatgtcttctcaagctcaccactacatctccagcctccccctttgggcaaa
aaaagtgatcatggcaacaccttctttccaaacagcccttcgccctttacaccaccacct
cctcaaacaccttctcctcacggcacaagaaggcacctgccgtcaccaccattaacacaa
gaagtggaccttcattccatggctgggccacctgttcctccacgacaaagcacttctcag
catatccctaaactccctccaaaaacttacaaaagggagcatacgcacccatccatgcac
agagatggacccccactgttggagaacgcccattcttcctga
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integrated database retrieval system
