Phyllostomus discolor (pale spear-nosed bat): 114500997
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Entry
114500997 CDS
T07739
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00140
Steroid hormone biosynthesis
pdic01100
Metabolic pathways
pdic05215
Prostate cancer
Module
pdic_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
114500997 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
114500997 (SRD5A2)
Enzymes [BR:
pdic01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
114500997 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
114500997
NCBI-ProteinID:
XP_028373536
UniProt:
A0A6J2M1W1
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Position
6:complement(17832950..17880649)
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AA seq
253 aa
AA seq
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MPVHCQQSPVLAGSAALAAMGALILYLREPSGYGKYTGSVTAATHLPARAAWFLQELPSF
VVPAGMLLGQTRALLGAPGVVLLGLFCAHYFHRTFIYALLSKGRPFPIGILIKGFVFCMG
NGFLQSYYLIYCADYPAEWYTDIRFILGVFLFILGMGINIHSDYILYQLRKPGEIIYKIP
QGGLFTYVSGANFLGEIIEWIGFALATWSLPGLAFAFFSLCFLGLRAFHHHRFYLKIFED
YPKFRKALIPFIF
NT seq
762 nt
NT seq
+upstream
nt +downstream
nt
atgcccgttcactgtcagcagagcccggtgctggcgggcagcgccgctttagccgcgatg
ggggccctgatactgtacttaagggagccctccggctacgggaagtacacggggagtgtg
accgcagctacccacctgcccgcccgcgccgcctggttcctgcaggagctgccctccttc
gtggtcccggccgggatgctcctcggtcagacccgcgctctcctcggcgcgcccggggtt
gtgcttctgggcctcttttgcgcacattacttccacaggacatttatttatgccctcctc
agtaaagggaggccttttccaattgggatacttatcaaaggctttgtcttctgcatggga
aatggattcctgcaaagctactacctgatttactgcgctgactaccctgctgagtggtac
acagacatacggtttatcctgggtgtcttcctatttatcttgggaatgggaatcaacatt
cacagtgactatatattgtaccagctccggaagcctggagaaatcatctataagattcca
caaggtggcttgttcacatacgtttcaggagccaatttcctcggtgagatcatcgaatgg
atcggctttgccctggccacctggtccctcccaggacttgcatttgcatttttctcgctt
tgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatctttgaggac
taccccaaatttcggaaagccctcattccatttatcttttaa
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