Phyllostomus discolor (pale spear-nosed bat): 114501294
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Entry
114501294 CDS
T07739
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
114501294 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pdic03032
]
114501294 (TOP2B)
03036 Chromosome and associated proteins [BR:
pdic03036
]
114501294 (TOP2B)
Enzymes [BR:
pdic01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
114501294 (TOP2B)
DNA replication proteins [BR:
pdic03032
]
Eukaryotic type
DNA Topoisomerases
114501294 (TOP2B)
Chromosome and associated proteins [BR:
pdic03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
114501294 (TOP2B)
Centrosome formation proteins
Centriole proteins
114501294 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
114501294
NCBI-ProteinID:
XP_028373638
UniProt:
A0A6J2M6D9
LinkDB
All DBs
Position
7:19989015..20052258
Genome browser
AA seq
1619 aa
AA seq
DB search
MAKAGGGGGAGAGGNGALTWVNNAVKKEESETANRNDSSKKLSVERVYQKKTQLEHILLR
PDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIK
VSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYG
AKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKF
KMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVAL
KVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNK
AGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCG
IVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAK
SLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAE
SLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQE
LSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDD
AAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILF
SNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMM
TIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSPLARRLFPAVDDNLL
KFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPH
PMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNG
TDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHM
GCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIAIE
NRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEESQNQHDDSSSDSGTPSGPDFNYIL
NMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDM
MAGMAGKAVKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKGDLDT
TAVKVEFDEEFSGTPVEGTGEEALIQTVPVNKGPKPKREKKEPGTRVRKRKTPTSSGKPG
AKKMKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
DDDNNDLEELKVKASPITNDGDDEYVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFG
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTP
KPKRTPKQKKVETINSDSDSEFGIPKKTTTPKGKGRGARKRKASGSENEGDYNPGRKTSK
PPSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDDEEDVDFAMFN
NT seq
4860 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggtggcggcgcgggagccggcggcaacggggcactgacctgg
gtgaacaatgctgtaaaaaaagaagaatcggaaactgcaaacagaaatgattcttcaaag
aagttgtctgttgagagagtatatcagaagaagacacaacttgaacacattctccttcgt
cctgacacatacatcgggtccgtggagccattgacacagctaatgtgggtgtatgatgaa
gatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaagatctttgat
gaaatcttggttaatgcagctgacaataaacagagggataagaacatgacctgtattaaa
gtttctattgatcccgaatctaacattataagcatttggaataatgggaaaggcattcca
gtagtagaacataaagtagagaaagtttatgttcctgcattaatttttggacagctttta
acatccagtaactatgatgatgatgagaaaaaagtaacaggtggccgtaatggttatggt
gcaaaactttgtaatattttcagtacaaagttcacagtagaaactgcttgcaaagaatac
aaacacagttttaaacagacatggatgaataatatgatgaagacttctgaagccaaaatt
aaacattttgatggtgaagattacacatgtataacattccaaccagatctgtccaaattt
aagatggaaaaacttgataaggacatcgtggccctcatgaccagaagagcttatgatttg
gctggttcctgcaaaggggtcaaggtcatgtttaatggaaagaaattgcctgtaaatgga
tttcgcagttatgtagatctttatgtgaaagacaaattggatgagactggagtggccctg
aaagttattcatgaacttgcaaatgaaagatgggatgtttgtcttacgttgagtgaaaaa
ggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggtggacgtcatgtg
gattatgtagtagatcaagttgttggtaaattgattgaagtagtcaagaaaaagaacaaa
gctggtgtatcagtgaaaccatttcaagtaaaaaaccatatatgggtttttattaattgc
cttatcgaaaacccaacttttgattctcagactaaggaaaacatgactctgcagcccaaa
agttttgggtccaaatgccagctatcagaaaaatttttcaaagcagcttctaactgtggc
attgtagaaagtatcctgaactgggtgaaatttaaggctcagactcagctgaacaagaag
tgttcgtcagtaaaatatagtaaaatcaaaggtattcccaaactggatgatgcaaatgat
gctggtggcaaacattccctggagtgtacactgatactaacagagggagactctgccaaa
tcgctggcagtgtctggattaggtgtgattggacgagacagatacggagtctttccactc
aggggaaaaattcttaatgtccgagaagcctctcataaacaaatcatggaaaatgcagaa
ataaacaatattattaaaatagttggtctacagtacaagaaaagttatgatgatgcagaa
tctctgaaaactttacgctatggaaagattatgattatgactgatcaggatcaagatgga
tctcacataaaaggcctgcttattaattttatacaccacaattggccatcacttttgaag
catggttttcttgaagagttcattactccaattgtaaaggcaagcaaaaacaagcaggaa
ctttccttctacagtattcctgaatttgatgagtggaaaaaacatatagaaaaccagaaa
gcctggaaaataaaatattacaaagggttgggtaccagtacagctaaagaagcaaaggaa
tattttgctgacatggaaaggcaccgcatcttgtttagatatgctggtcctgaggatgat
gctgccattacattggcattcagtaaaaagaagattgatgacagaaaagaatggttaaca
aattttatggaagatcggagacagcgtaggttgcatggattaccagagcaatttttatat
ggtacagcaacaaagcatttgacatacaatgatttcatcaacaaggaattgattctcttc
tcaaactcagacaatgaaagatctataccttctcttgttgatggctttaaaccaggccaa
cgaaaagttttatttacctgtttcaaaaggaatgataaacgtgaagtaaaagttgcccag
ttggctggatctgttgccgagatgtctgcttatcatcatggagaacaagcgttaatgatg
actattgtgaatttggctcagaactttgtgggaagtaacaacattaacttgcttcagcct
attggtcagtttggaactcggcttcatggtggcaaagatgctgcaagccctcgttacatt
ttcaccatgttaagccctttagcaagacggctttttcctgctgtggatgacaacctgcta
aaattcctttatgatgataatcaacgggtggagcctgagtggtatattcccataattccc
atggttttaataaatggtgctgagggcattggtactggatgggcttgtaaactacccaac
tatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcttggatcctcat
cccatgcttccaaactacaaaaactttaaaggaacaattcaagaactcggtcagaaccaa
tatgccgtcagtggtgaaatatttgtggtggatagaaacacagtggagattacagagctt
ccagttaggacttggacacaggtatacaaagaacaggttttagaacctatgctaaatgga
acagataaaacaccagcattaatttctgattataaagaatatcatactgatacaactgtg
aaatttgtggtgaaaatgaccgaagagaaattagcacaagcagaagctgctggattgcat
aaagtttttaaacttcaaactactcttacttgtaattccatggtactctttgatcatatg
ggatgtctgaagaagtatgaaactgtgcaagacattttgaaagaattctttgatttacgg
ttaagctattatggtttacgtaaggagtggcttgtagggatgttgggagcagaatctaca
aagcttaacaatcaagctcgtttcatattagagaagatacaagggaaaattgctatagag
aataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatctgaccca
gtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaatcacaaaaccag
catgatgatagttcctctgattcaggaactccttcaggccctgactttaattatatttta
aacatgtctctgtggtctcttactaaagagaaagttgaagagctgattaaacagagagat
acaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagatctttggaaagaa
gatttagcagcatttgtcgaagaactggataaagtagaagcgcaagaacgagaagatatg
atggccggaatggctggaaaagcagtaaagggtaaagttggcaaacccaaggtgaagaaa
cttcagttggaagagacaatgccctcaccttatgggaggagaatagttcccgaaatcact
gccatgaaggcagatgccagcaaaaagttgctgaagaagaaaaagggtgatcttgatacc
acagcagtaaaggtggaatttgatgaggaattcagtgggacacctgtagaaggtacagga
gaggaagcactgatccagacggttcctgtcaataaaggtcccaagcccaaaagagagaaa
aaggagcctggtaccagggtgagaaaaagaaaaacacctacatcatctggcaaacccggt
gcaaagaaaatgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagtgac
ttagaagagacagagcctgtggttattccaagagattctttacttaggagggcggctgcc
gagaggcctaaatacacatttgatttctcagaagaagaggatgatgatgctgatgatgat
gatgatgacaataatgatttagaggaactgaaagtcaaagcatctcccataacaaatgat
ggggatgatgaatatgttccttcagatggcctagataaagatgaatatacattttcacca
ggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaagagtcaggattttggg
aatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaatttgac
agtaatgaagaagattctgcttctgttttttcaccatcatttggtctgaaacaaacagat
aaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagatacaacccct
aagcccaagagaacccccaaacagaagaaagtagagactatcaactctgactcggattca
gaatttggcattccaaagaagactacaacaccaaaaggtaaaggtcgaggggcaaggaaa
aggaaagcatctggctccgaaaatgaaggcgactataacccgggcaggaaaacgtccaaa
ccaccaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggacatcttc
ccatcagacttcacttctgaaccaccttctctgccacggaccggtcgagctaggaaagaa
gtaaaatattttgcagagtctgatgatgaagaagatgtcgattttgcaatgtttaattaa
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integrated database retrieval system
