KEGG   Phyllostomus discolor (pale spear-nosed bat): 114502442
Entry
114502442         CDS       T07739                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01522  Endocrine resistance
pdic04010  MAPK signaling pathway
pdic04014  Ras signaling pathway
pdic04020  Calcium signaling pathway
pdic04024  cAMP signaling pathway
pdic04062  Chemokine signaling pathway
pdic04081  Hormone signaling
pdic04082  Neuroactive ligand signaling
pdic04114  Oocyte meiosis
pdic04140  Autophagy - animal
pdic04211  Longevity regulating pathway
pdic04213  Longevity regulating pathway - multiple species
pdic04261  Adrenergic signaling in cardiomyocytes
pdic04270  Vascular smooth muscle contraction
pdic04310  Wnt signaling pathway
pdic04340  Hedgehog signaling pathway
pdic04371  Apelin signaling pathway
pdic04530  Tight junction
pdic04540  Gap junction
pdic04611  Platelet activation
pdic04713  Circadian entrainment
pdic04714  Thermogenesis
pdic04720  Long-term potentiation
pdic04723  Retrograde endocannabinoid signaling
pdic04724  Glutamatergic synapse
pdic04725  Cholinergic synapse
pdic04726  Serotonergic synapse
pdic04727  GABAergic synapse
pdic04728  Dopaminergic synapse
pdic04740  Olfactory transduction
pdic04742  Taste transduction
pdic04750  Inflammatory mediator regulation of TRP channels
pdic04910  Insulin signaling pathway
pdic04911  Insulin secretion
pdic04912  GnRH signaling pathway
pdic04913  Ovarian steroidogenesis
pdic04914  Progesterone-mediated oocyte maturation
pdic04915  Estrogen signaling pathway
pdic04916  Melanogenesis
pdic04918  Thyroid hormone synthesis
pdic04919  Thyroid hormone signaling pathway
pdic04921  Oxytocin signaling pathway
pdic04922  Glucagon signaling pathway
pdic04923  Regulation of lipolysis in adipocytes
pdic04924  Renin secretion
pdic04925  Aldosterone synthesis and secretion
pdic04926  Relaxin signaling pathway
pdic04927  Cortisol synthesis and secretion
pdic04928  Parathyroid hormone synthesis, secretion and action
pdic04934  Cushing syndrome
pdic04935  Growth hormone synthesis, secretion and action
pdic04961  Endocrine and other factor-regulated calcium reabsorption
pdic04962  Vasopressin-regulated water reabsorption
pdic04970  Salivary secretion
pdic04971  Gastric acid secretion
pdic04976  Bile secretion
pdic05012  Parkinson disease
pdic05020  Prion disease
pdic05030  Cocaine addiction
pdic05031  Amphetamine addiction
pdic05032  Morphine addiction
pdic05034  Alcoholism
pdic05146  Amoebiasis
pdic05163  Human cytomegalovirus infection
pdic05165  Human papillomavirus infection
pdic05166  Human T-cell leukemia virus 1 infection
pdic05200  Pathways in cancer
pdic05203  Viral carcinogenesis
pdic05205  Proteoglycans in cancer
pdic05207  Chemical carcinogenesis - receptor activation
pdic05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114502442 (PRKACA)
   04014 Ras signaling pathway
    114502442 (PRKACA)
   04310 Wnt signaling pathway
    114502442 (PRKACA)
   04340 Hedgehog signaling pathway
    114502442 (PRKACA)
   04371 Apelin signaling pathway
    114502442 (PRKACA)
   04020 Calcium signaling pathway
    114502442 (PRKACA)
   04024 cAMP signaling pathway
    114502442 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    114502442 (PRKACA)
   04081 Hormone signaling
    114502442 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114502442 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    114502442 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    114502442 (PRKACA)
   04540 Gap junction
    114502442 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    114502442 (PRKACA)
   04062 Chemokine signaling pathway
    114502442 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    114502442 (PRKACA)
   04910 Insulin signaling pathway
    114502442 (PRKACA)
   04922 Glucagon signaling pathway
    114502442 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    114502442 (PRKACA)
   04912 GnRH signaling pathway
    114502442 (PRKACA)
   04913 Ovarian steroidogenesis
    114502442 (PRKACA)
   04915 Estrogen signaling pathway
    114502442 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    114502442 (PRKACA)
   04921 Oxytocin signaling pathway
    114502442 (PRKACA)
   04926 Relaxin signaling pathway
    114502442 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    114502442 (PRKACA)
   04918 Thyroid hormone synthesis
    114502442 (PRKACA)
   04919 Thyroid hormone signaling pathway
    114502442 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    114502442 (PRKACA)
   04916 Melanogenesis
    114502442 (PRKACA)
   04924 Renin secretion
    114502442 (PRKACA)
   04925 Aldosterone synthesis and secretion
    114502442 (PRKACA)
   04927 Cortisol synthesis and secretion
    114502442 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    114502442 (PRKACA)
   04270 Vascular smooth muscle contraction
    114502442 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    114502442 (PRKACA)
   04971 Gastric acid secretion
    114502442 (PRKACA)
   04976 Bile secretion
    114502442 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    114502442 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    114502442 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    114502442 (PRKACA)
   04727 GABAergic synapse
    114502442 (PRKACA)
   04725 Cholinergic synapse
    114502442 (PRKACA)
   04728 Dopaminergic synapse
    114502442 (PRKACA)
   04726 Serotonergic synapse
    114502442 (PRKACA)
   04720 Long-term potentiation
    114502442 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    114502442 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    114502442 (PRKACA)
   04742 Taste transduction
    114502442 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    114502442 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    114502442 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    114502442 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    114502442 (PRKACA)
   04714 Thermogenesis
    114502442 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114502442 (PRKACA)
   05205 Proteoglycans in cancer
    114502442 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    114502442 (PRKACA)
   05203 Viral carcinogenesis
    114502442 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114502442 (PRKACA)
   05163 Human cytomegalovirus infection
    114502442 (PRKACA)
   05165 Human papillomavirus infection
    114502442 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    114502442 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    114502442 (PRKACA)
   05020 Prion disease
    114502442 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    114502442 (PRKACA)
   05031 Amphetamine addiction
    114502442 (PRKACA)
   05032 Morphine addiction
    114502442 (PRKACA)
   05034 Alcoholism
    114502442 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    114502442 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    114502442 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114502442 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114502442 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:pdic03019]
    114502442 (PRKACA)
   03036 Chromosome and associated proteins [BR:pdic03036]
    114502442 (PRKACA)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     114502442 (PRKACA)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: AGC group
  PKA family
   114502442 (PRKACA)
Messenger RNA biogenesis [BR:pdic03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     114502442 (PRKACA)
Chromosome and associated proteins [BR:pdic03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    114502442 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 114502442
NCBI-ProteinID: XP_028375188
UniProt: A0A6J2MAQ1
LinkDB
Position
8:45101756..45117347
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgcagccaagaagggcagcgagcaggagagtgtgaaagaattctta
gccaaagccaaagaagattttcttaaaaaatgggaaaatcctgctcagaatacagcccat
ttggatcagtttgaacgaatcaagaccctcggcacaggctcctttgggcgggtgatgcta
gtgaaacacaaggagactgggaaccacttcgccatgaagatcctggacaaacagaaggtg
gtaaagctgaaacagatcgagcacaccctgaatgagaagcgcatcctacaggctgtcaac
tttccgttccttgtcagacttgagttctccttcaaggacaactcaaatttatacatggtc
atggagtatgtacctggtggggaaatgttctcacacctacggcggatcggaaggttcagc
gagccccatgcccgcttctatgctgcccagattgtcctgaccttcgagtacctgcactca
ctggatctcatctaccgggacctgaagccggagaaccttctcatagaccagcagggctat
attcaggtgacagactttggttttgccaagcgtgtgaagggccgcacctggaccttgtgt
gggaccccggagtacctggcccccgagatcatcctgagcaaaggctacaacaaggctgtg
gactggtgggccctgggggttctcatctatgagatggcagccggctacccgcccttcttt
gctgaccagcccattcagatctatgagaagattgtttctgggaaggtgcggttcccgtct
cacttcagctctgacctgaaggatctgctgcggaacctcctgcaggtggatcttaccaag
cgctttgggaacctcaagaacggggtgaatgacatcaagaaccacaaatggtttgccacg
actgactggattgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacaagtaactttgacgactatgaagaggaagagatccgagtgtccatc
aatgagaagtgtggcaaggagttttctgagttttag

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