Phyllostomus discolor (pale spear-nosed bat): 114502466
Help
Entry
114502466 CDS
T07739
Symbol
NF1
Name
(RefSeq) neurofibromin isoform X5
KO
K08052
neurofibromin 1
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521
EGFR tyrosine kinase inhibitor resistance
pdic04010
MAPK signaling pathway
pdic04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114502466 (NF1)
04014 Ras signaling pathway
114502466 (NF1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114502466 (NF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
114502466
NCBI-ProteinID:
XP_028375244
UniProt:
A0A6J2M7E2
LinkDB
All DBs
Position
8:80579411..80805687
Genome browser
AA seq
2841 aa
AA seq
DB search
MAAHRPVEWVQAVVNRFDDQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEVIQDITKDAVDENNMNKKLFL
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
REILICRNKFLLKNKQADRSSCHFLFFYGVGCDIPSSGTASQMAMDHEELLRTCTPGASL
RKGKGNTSMDSAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD
IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRTALQKRVMALLRRIEHPTAGNTEAWE
DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI
NMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRL
LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT
QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL
VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS
LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL
ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE
TVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLW
NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS
FEVDPTRLEQSESLEENQRNLLQMTEKFFQAIISSSSEFPPQLRSVCHCLYQATCHSLLN
KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG
LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSF
ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH
WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI
NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY
IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK
VFHNALRLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ
FTLTIANQGTPLTFMHQECDAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA
LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN
EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL
ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL
ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA
HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL
PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR
DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC
LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL
EQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY
RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR
KSLLLTDISMENVPMDTYPIHHGDPGYRTLKENQPWSSPKGSEGYLAATYPTVGQTSPRA
RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYE
METQRISSAQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRI
LYEYLAEASVVFPRVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQY
QTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTP
TSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSA
SQVQKQRSTGSFKRNSIKKIV
NT seq
8526 nt
NT seq
+upstream
nt +downstream
nt
atggccgcgcacaggccggtggaatgggtccaggccgtggtcaaccgcttcgacgatcag
cttccaataaaaacaggacagcagaacacacataccaaagtcagtactgaacacaacaag
gaatgtcttatcaatatttccaaatacaagttttctttggttataagcggcctcactact
atcttaaagaatgttaacaatatgagaatatttggagaagctgctgaaaaaaatttatat
ctctctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggac
acaatgagattagatgaaacaatgctcgtcaaacagttgctgccagaaatctgccatttc
cttcacacctgtcgtgaaggaaaccaacatgcagctgagcttcggaattccgcctctggg
gttttattttctctcagctgcaacaacttcaacgcggtcttcagtcgcatttctaccagg
ttacaggaattgaccgtttgttcagaagacaatgttgatgttcatgatatagaattgtta
cagtatatcaatgtggattgtgcaaaattaaaacgactcctgaaggaaacagcatttaaa
tttaaagccctaaagaaggttgcacagttagcagttataaatagcctggaaaaagcattt
tggaactgggtagaaaattacccagatgaatttacaaagctataccagattccacagact
gatatggctgagtgtgcagaaaaactctttgacttggtggatggttttgcagaaagcacc
aaacgtaaagcggcagtttggccactacagatcattcttcttatcttgtgtccagaagta
atccaggacataaccaaggatgcggttgatgaaaataacatgaataagaagttgtttctg
gacagtctacgaaaagcacttgctggccatggaggaagcaggcagctgactgagagtgct
gcaatcgcctgcgtcaaactgtgtaaagcaagcacctacatcaattgggaagataactcc
gtcatcttcctgctagttcagtccatggtggttgatcttaagaacctgctttttaatcca
agtaaaccattctcgagaggcagtcagcctgcagatgtggatctgatgattgactgcctc
gtttcttgctttcgtataagccctcacaacaaccaacactttaagatttgcctggctcag
aattccccatctacatttcactacgtgctggtaaattcactccatcgaatcatcaccaat
tctgcattggattggtggcctaagattgatgccgtgtattgtcactcagttgaacttcga
aatatgtttggtgaaacacttcataaagcagtgcagggctgcggagcccacccagcaata
cgaatggcaccgagtcttacgtttaaagaaaaagtaacaagccttaaatttaaagaaaaa
cctacagacctggagacaagaagctataagtatcttctcttgtccatggtgaaactaatt
catgcagatccaaagctcttgctttgtaatccaagaaagcaggggcctgaaacccaaggc
agcacagcagaattaataacgggacttgtccagctggtccctcagtcacacatgccagag
atcgctcaggaagcaatggaggccctgcttgttcttcatcagttggatagcattgatttg
tggaatcccgatgctcctgtggaaacattttgggaaattagctcacaaatgcttttttat
atctgcaagaaattaacaagccatcaaatgcttagtagcacagaaattctcaaatggttg
cgggaaattttgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagc
tcctgtcactttctattcttttacggggtaggatgtgacattccttctagtggaactgcc
agtcagatggccatggatcacgaagagttactccgaacttgtactcctggagcctctctc
cggaaggggaaagggaacacgtccatggatagtgcagcagggtgcagtggaaccccacca
atatgccgacaggcccagaccaaactggaagtggccttgtacatgtttctgtggagccct
gacactgaagctgttctggttgccatgtcctgtttccgccacctctgtgaggaagcagat
atccggtgcggggtggacgaggtgtcagtgcacaacttcttgcccaactacaatacattc
atggagtttgcctctgtcagcaatatgatgtcaacggggagaacagcccttcagaaaaga
gtgatggcactactaaggcgcattgagcatcccactgctggaaacactgaggcttgggaa
gatacgcatgcaaaatgggaacaagctacaaaactaatcctcaactatccaaaagccaaa
atggaagatggccaggctgctgaaagccttcacaagaccattgttaagaggcgaatgtct
catgtgagtggaggaggatccatcgacttgtctgacacggactccctacaggagtggatc
aacatgactggcttcctctgtgcccttgggggagtatgcctgcagcagaggagcaattct
ggcctggccacctatagccctcccatgggccccgtcagcgaacgcaagggttccatgatt
tcagtgatgtcctcagaaggaaatgcagatacccctgtcagcaaatttatggaccgactg
ctgtccttaatggtgtgtaaccatgagaaagtagggctgcagatacggaccaatgtgaag
gacctggtgggtctagaattgagtcctgcgctttatccaatgctatttaacaaactgaag
aataccatcagcaaattctttgactcacaaggacaggttttactgactgacaccaatact
cagtttgtagagcaaaccatcgctataatgaagaacttactagataaccatactgaaggc
agctctgaacacctggggcaagctagcattgaaacaatgatgttaaatttggtcagatat
gttcgtgtgcttgggaatatggtccatgcaattcagataaaaacgaaactgtgtcagtta
gtcgaggtaatgatggcaaggagagacgacctctcattttgtcaagagatgaagtttagg
aataagatggtagaatacttgacagactgggttatgggaacatcaaaccaagcagcagat
gatgatgtcaaatgtcttacaagagacttggaccaggcaagcatggaagcagtggtttca
ctcctggctggtcttccgctgcagcccgaggaaggagatggtgtggaactaatggaagcc
aaatcacagttatttcttaagtatttcacattgtttatgaaccttttgaacgactgtagt
gaagttgaagatgaaaatgcacagacaggtggcaggaaacgtggcatgtctcggaggctg
gcctcattgaggcactgtacagtccttgcgatgtccaacttgctcaatgctaatgtggac
agcggcctcatgcactctataggtttaggttatcacaaagatcttcagacaagagctaca
tttatggaagttctgacaaaaatcctccaacaaggcacagaatttgacacacttgcagaa
acagtgttggcagatcggtttgagagattggtggagctggtcacgatgatgggtgatcag
ggagagctccctatagctatggccctggccaacgtggttccttgttctcagtgggatgaa
ctagctcgagttctggtgactctctttgattctcggcatttactctaccaactgctctgg
aacatgttttctaaggaagtagaattggcagactccatgcagactcttttccgaggcaac
agcttagctagtaaaataatgaccttctgtttcaaggtatacggtgctacctacctacaa
aaactcctggatcctttattacgaattgtgatcacatcctctgattggcagcacgtgagc
tttgaagtggaccctaccaggttagaacagtcagagagccttgaggaaaaccagcggaac
ctccttcagatgactgaaaagttcttccaggccatcatcagttcctcctcagaatttccc
cctcagcttcgaagtgtgtgccactgtttataccaggcaacttgccactccctactgaat
aaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgttttcct
cagaacagcatcggtgcagtaggaagtgccatgttcctcagatttatcaatcctgccatt
gtctcaccgtatgaagcagggattttagataaaaagccaccacctagaattgaaaggggc
ttgaagttaatgtcaaagatacttcagagtattgccaatcatgttctcttcacaaaagaa
gagcatatgcggccttttaatgattttgtaaaaagcaactttgatgcagcacgaaggttt
ttccttgatatagcatctgattgtcccacaagtgatgcagtaaatcatagtctttccttc
atcagtgatggcaatgtgcttgctttacatcgtctgctctggaacaatcaggagaaaatt
ggccagtatctttccagcaatagggatcacaaagctgtggggagacggccttttgataag
atggcaacacttcttgcgtacctggggcctccggagcacaaacctgtggcagatacacac
tggtccagtcttaaccttactagttcaaagtttgaggaattcatgactaggcatcaagta
catgaaaaagaagaattcaaggctttgaaaacattaagtattttctaccaagctgggact
tccaaagctgggaatcctatattttattatgttgcacggaggttcaaaactggtcaaatc
aatggggatttgctaatatatcatgtcttgctgactttaaagccatattatgcaaagcca
tatgaaattgtagtggaccttacccatactgggcctagcaatcgctttaaaacggacttc
ctctctaagtggtttgttgtttttcctggctttgcttatgacaacgtctccgcagtttac
atctataactgtaactcctgggtcagggagtataccaagtatcatgagcgactactgact
ggcctcaaaggcagcaaaaggctcattttcatagactgccccgggaagctggctgagcac
atagaacacgaacaacagaaactgcccgctgccaccttggctttagaagaggacctgaag
gtgttccacaatgctctcaggctagctcacaaagacaccaaagtttctattaaagttggt
tctactgctgttcaggtaacctcagcagagcgaacaaaagtcctggggcagtcagtcttt
ctaaatgatatctattatgcttcggaaattgaagaaatctgcctggtggatgagaaccag
ttcaccttaaccatcgcaaaccagggcacaccactcaccttcatgcaccaggagtgtgat
gccattgtccagtctatcattcacatccggacgcgctgggagctgtcgcagcctgattcc
atcccccagcacaccaagattcggcccaaagatgtccctgggacactgctcaatattgca
ttgctcaatttaggcagttcagacccgagtttacggtcagctgcctataatcttctgtgt
gccttaacttgtacctttaatttaaaaatcgagggccagttactagagacatcaggttta
tgtatccctgctaacaacaccctcttcatcgtctcgattagtaagacgctggctgccaat
gagccacacctcaccttagaatttttggaagagtgtatttctggatttagcaagtctagt
attgaattgaaacacctttgtttagaatacatgactccatggctgtcaaatctggtccgt
ttttgtaagcacaacgatgatgccaaacgacaaagagttactgctattctggataagcta
ataacaatgaccataaatgagaagcagatgtacccatccatccaagcaaaaatatggggg
agccttgggcagattacagatctccttgatgttgtactagacagtttcatcaaaaccagt
gcaacgggtggcttgggatcgataaaagctgaggtgatggcagatactgctgtagctctg
gcttctggaaacgtgaaattggtttcaagcaaggttattggaaggatgtgcaaaataatt
gacaagacatgcttatctccgacccctactttagagcagcatctcatgtgggacgatatt
gctattctcgcgcgctacatgctaatgctgtccttcaacaactctctggatgtagcagct
catctcccctacctcttccacgtggtcacgttcttagtggccacagggccactctccctt
agagcttccacacacggattggtcattaatatcattcactctctgtgtacttgttcacag
cttcattttagtgaagagaccaagcaggttttgagactcagtttgacagagttctcatta
cccaaattttacttgctgtttggcatcagcaaagtgaagtcagccgctgtcattgccttc
cgctccagttaccgggacaggtcattctctcctggctcctatgagagggagactttcgct
ttgacatccttggaaacagtcacagaggctttgctagagatcatggaggcatgtatgaga
gatattcccacatgcaagtggctggaccagtggacagaactagctcaaagatttgcattt
caatataatccatcccttcaaccaagagctcttgttgtcttcggctgcattagcaaacga
gtgtctcatgggcagataaagcagattatccgtattctcagcaaggcacttgagagttgc
ttaaaaggacctgatacttacaacagtcaagttctgatagaggccacagtaatagcacta
accaaattacagccgctccttaataaggactcccctttgcacaaagccctcttttgggta
gctgtggctgtgctgcagcttgacgaggtcaacttgtattcagcaggcaccgcactcctg
gaacaaaacctgcacaccttagacagtctccggatattcaatgacaagagcccggaggag
gtgtttatggcgatccggaaccctctggaatggcactgcaagcaaatggatcattttgtt
ggactcaatttcaactcgaactttaactttgccctggttgggcacctcttaaaagggtac
agacatccttcacctgccattgttgccagaacagtcagaattttgcatacgctactaact
ctggttaacaaacatagaaattgtgacaaatttgaggtgaatacacagagcgtggcttat
ttagcagctttactcacagtgtctgaggaggttcgaagtcgttgtagcctaaaacataga
aagtctcttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccatt
catcatggtgaccctggctataggacactgaaggagaatcagccatggtcctctcccaaa
ggttctgaaggttaccttgcagccacgtacccaactgtgggccagaccagtccccgggcc
aggaaatccatgagcttggacatggggcagccttctcaggccaacacgaagaagttgctt
ggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaa
atggaatcagggatcacaacaccccccaaaatgaggagagtagcagaaactgattatgaa
atggaaactcaaaggatttcctcagcacagcagcatccccatttacggaaagtctccgtg
tcagaatcgaatgttctcttggatgaagaagtacttactgatccaaagatccaagcactt
cttcttactgttctggctacactggtaaaatacaccacggatgagtttgatcaacgaatt
ctttatgaatatttagcagaagccagtgttgttttccccagagtttttcctgttgtgcac
aatttgttggactctaagatcaacaccttattgtcgttgtgccaagatccaaatttatta
aatccaattcatggaattgtgcagagtgtggtataccatgaagagtccccaccacagtac
cagacgtcttacctgcagagttttgggtttaatggcttgtggcggtttgcaggacccttt
tcaaagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttg
attgacacgtatttgcctggaattgatgaagaagccagtgaggagtccctcctgacaccc
acatctccttatcctcctgcagtgcagagccagcttagtattactgctaaccttaacctt
tctaattccatgacctcacttgcaacttcccagcattccccaggaattgacaaggagaac
gtggagctctccccaaccaccgggcactgtaatagtggacggactcgccatggatccgca
agccaggtgcagaagcaaagaagcactggcagtttcaaacgtaatagcattaagaagatc
gtgtga
DBGET
integrated database retrieval system
