KEGG   Phyllostomus discolor (pale spear-nosed bat): 114502829
Entry
114502829         CDS       T07739                                 
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha type
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521  EGFR tyrosine kinase inhibitor resistance
pdic04010  MAPK signaling pathway
pdic04012  ErbB signaling pathway
pdic04014  Ras signaling pathway
pdic04015  Rap1 signaling pathway
pdic04020  Calcium signaling pathway
pdic04066  HIF-1 signaling pathway
pdic04070  Phosphatidylinositol signaling system
pdic04071  Sphingolipid signaling pathway
pdic04072  Phospholipase D signaling pathway
pdic04082  Neuroactive ligand signaling
pdic04150  mTOR signaling pathway
pdic04151  PI3K-Akt signaling pathway
pdic04261  Adrenergic signaling in cardiomyocytes
pdic04270  Vascular smooth muscle contraction
pdic04310  Wnt signaling pathway
pdic04360  Axon guidance
pdic04370  VEGF signaling pathway
pdic04510  Focal adhesion
pdic04540  Gap junction
pdic04613  Neutrophil extracellular trap formation
pdic04650  Natural killer cell mediated cytotoxicity
pdic04664  Fc epsilon RI signaling pathway
pdic04666  Fc gamma R-mediated phagocytosis
pdic04670  Leukocyte transendothelial migration
pdic04713  Circadian entrainment
pdic04720  Long-term potentiation
pdic04723  Retrograde endocannabinoid signaling
pdic04724  Glutamatergic synapse
pdic04725  Cholinergic synapse
pdic04726  Serotonergic synapse
pdic04727  GABAergic synapse
pdic04728  Dopaminergic synapse
pdic04730  Long-term depression
pdic04750  Inflammatory mediator regulation of TRP channels
pdic04911  Insulin secretion
pdic04912  GnRH signaling pathway
pdic04916  Melanogenesis
pdic04918  Thyroid hormone synthesis
pdic04919  Thyroid hormone signaling pathway
pdic04921  Oxytocin signaling pathway
pdic04925  Aldosterone synthesis and secretion
pdic04926  Relaxin signaling pathway
pdic04928  Parathyroid hormone synthesis, secretion and action
pdic04929  GnRH secretion
pdic04933  AGE-RAGE signaling pathway in diabetic complications
pdic04935  Growth hormone synthesis, secretion and action
pdic04960  Aldosterone-regulated sodium reabsorption
pdic04961  Endocrine and other factor-regulated calcium reabsorption
pdic04970  Salivary secretion
pdic04971  Gastric acid secretion
pdic04972  Pancreatic secretion
pdic05017  Spinocerebellar ataxia
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05031  Amphetamine addiction
pdic05032  Morphine addiction
pdic05143  African trypanosomiasis
pdic05146  Amoebiasis
pdic05161  Hepatitis B
pdic05163  Human cytomegalovirus infection
pdic05164  Influenza A
pdic05170  Human immunodeficiency virus 1 infection
pdic05171  Coronavirus disease - COVID-19
pdic05200  Pathways in cancer
pdic05205  Proteoglycans in cancer
pdic05206  MicroRNAs in cancer
pdic05207  Chemical carcinogenesis - receptor activation
pdic05214  Glioma
pdic05223  Non-small cell lung cancer
pdic05225  Hepatocellular carcinoma
pdic05231  Choline metabolism in cancer
pdic05415  Diabetic cardiomyopathy
pdic05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114502829 (PRKCA)
   04012 ErbB signaling pathway
    114502829 (PRKCA)
   04014 Ras signaling pathway
    114502829 (PRKCA)
   04015 Rap1 signaling pathway
    114502829 (PRKCA)
   04310 Wnt signaling pathway
    114502829 (PRKCA)
   04370 VEGF signaling pathway
    114502829 (PRKCA)
   04066 HIF-1 signaling pathway
    114502829 (PRKCA)
   04020 Calcium signaling pathway
    114502829 (PRKCA)
   04070 Phosphatidylinositol signaling system
    114502829 (PRKCA)
   04072 Phospholipase D signaling pathway
    114502829 (PRKCA)
   04071 Sphingolipid signaling pathway
    114502829 (PRKCA)
   04151 PI3K-Akt signaling pathway
    114502829 (PRKCA)
   04150 mTOR signaling pathway
    114502829 (PRKCA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    114502829 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114502829 (PRKCA)
   04540 Gap junction
    114502829 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    114502829 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    114502829 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    114502829 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    114502829 (PRKCA)
   04670 Leukocyte transendothelial migration
    114502829 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    114502829 (PRKCA)
   04929 GnRH secretion
    114502829 (PRKCA)
   04912 GnRH signaling pathway
    114502829 (PRKCA)
   04921 Oxytocin signaling pathway
    114502829 (PRKCA)
   04926 Relaxin signaling pathway
    114502829 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    114502829 (PRKCA)
   04918 Thyroid hormone synthesis
    114502829 (PRKCA)
   04919 Thyroid hormone signaling pathway
    114502829 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    114502829 (PRKCA)
   04916 Melanogenesis
    114502829 (PRKCA)
   04925 Aldosterone synthesis and secretion
    114502829 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    114502829 (PRKCA)
   04270 Vascular smooth muscle contraction
    114502829 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    114502829 (PRKCA)
   04971 Gastric acid secretion
    114502829 (PRKCA)
   04972 Pancreatic secretion
    114502829 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    114502829 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    114502829 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    114502829 (PRKCA)
   04727 GABAergic synapse
    114502829 (PRKCA)
   04725 Cholinergic synapse
    114502829 (PRKCA)
   04728 Dopaminergic synapse
    114502829 (PRKCA)
   04726 Serotonergic synapse
    114502829 (PRKCA)
   04720 Long-term potentiation
    114502829 (PRKCA)
   04730 Long-term depression
    114502829 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    114502829 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114502829 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    114502829 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    114502829 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114502829 (PRKCA)
   05206 MicroRNAs in cancer
    114502829 (PRKCA)
   05205 Proteoglycans in cancer
    114502829 (PRKCA)
   05207 Chemical carcinogenesis - receptor activation
    114502829 (PRKCA)
   05231 Choline metabolism in cancer
    114502829 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    114502829 (PRKCA)
   05214 Glioma
    114502829 (PRKCA)
   05223 Non-small cell lung cancer
    114502829 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114502829 (PRKCA)
   05161 Hepatitis B
    114502829 (PRKCA)
   05171 Coronavirus disease - COVID-19
    114502829 (PRKCA)
   05164 Influenza A
    114502829 (PRKCA)
   05163 Human cytomegalovirus infection
    114502829 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    114502829 (PRKCA)
   05143 African trypanosomiasis
    114502829 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    114502829 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    114502829 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    114502829 (PRKCA)
   05032 Morphine addiction
    114502829 (PRKCA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114502829 (PRKCA)
   05415 Diabetic cardiomyopathy
    114502829 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    114502829 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    114502829 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114502829 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pdic04131]
    114502829 (PRKCA)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     114502829 (PRKCA)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   114502829 (PRKCA)
Membrane trafficking [BR:pdic04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    114502829 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2 Kinase-like
Other DBs
NCBI-GeneID: 114502829
NCBI-ProteinID: XP_028375847
UniProt: A0A6J2M785
LinkDB
Position
8:88067442..88423685
AA seq 670 aa
MADVFPANDSTAPQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLRAEVADEKLHVIVQDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SIEIWDWDRTTRNDFMGSLSFGVSELMKMPACGWYKLLNQEEGEYYNVPIPEGDDEGNME
LRQKFEKAKLGPAKKVISPSEDRRFSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE
ELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNG
GDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKKGIIYRDLKLDNVMLDSEGHIKIADF
GMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED
EDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDW
EKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVISNIDQSDFEGFSYVNPQ
FVHPILQSAA
NT seq 2013 nt   +upstreamnt  +downstreamnt
atggctgacgttttcccggccaacgactccacggcgcctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgagacagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa
tttgtcacattttcttgtccgggtgcggacaagggacccgacactgacgaccccaggagc
aagcacaagtttaaaatccacacctatggcagccccaccttctgtgaccactgcgggtcg
ctgctgtacggactcatccatcaggggatgaaatgcgacacctgcgacatgaacgtgcac
aagcagtgcgtcatcaacgtccccagcctctgcgggatggaccacactgagaagaggggc
cggatctacctgagggctgaggtcgctgacgaaaagctccatgtcatagtgcaagatgca
aaaaatctaatccccatggatccaaatggactttcagacccttacgtgaagctgaaactt
attcctgatcccaagaacgagagcaaacaaaaaaccaaaactatccgctccacactaaac
ccccagtggaacgagtccttcacgttcaaattaaaaccttcagataaagaccgacgactg
tccatagagatctgggactgggatcggacaacgaggaacgacttcatgggatccctctcc
ttcggcgtctcagagctcatgaagatgccggcctgcgggtggtacaagctgctcaaccaa
gaagaaggcgagtactacaatgtgcccattccagaaggggacgatgaaggaaacatggag
ctcaggcagaagttcgagaaagccaagcttggccccgccaagaaagtgatcagcccttca
gaagaccggagattttccaacaacctggacagagtgaagctcactgacttcaacttcctc
atggtgctggggaaggggagtttcggaaaggtgatgctggctgataggaagggaacagaa
gaactctatgccatcaaaatcctgaagaaggacgtggtgattcaagacgacgacgtggag
tgcaccatggtggaaaagcgggtcctggccctgctcgacaagccccccttcctgacgcag
ctgcactcctgcttccagacagtggaccggctgtacttcgtcatggaatacgtcaacggc
ggggacctcatgtaccacattcagcaagtagggaaattcaaggagccacaggcagtattc
tacgcagcagagatttccattggactgttctttcttcataaaaaaggaatcatttacagg
gacctgaagttagacaacgtcatgctggactccgaagggcacatcaagatcgctgacttc
gggatgtgcaaggagcacatgatggacggggtcacgaccagaaccttctgtgggacccca
gattacatcgccccagagatcatcgcctaccagccgtatgggaagtccgtggactggtgg
gcctacggcgtcctgctgtacgaaatgctggccgggcagcctccgtttgatggcgaagat
gaagacgagctgttccagtccatcatggagcacaacgtctcgtacccgaagtccctgtcc
aaggaggccgtttccatctgcaaagggctgatgaccaagcatccaggcaagcggctgggc
tgcgggcccgagggagagcgggacgtgcgcgaacacgccttcttccggaggatcgactgg
gagaaactggagaaccgggagatccagccgcccttcaagcccaaagtgtgcggcaaaggg
gcggaaaactttgacaagttcttcacacgcgggcaaccggtcttaacgcctccggatcag
ctggtcatctctaacatagaccagtctgatttcgagggcttctcgtatgtcaacccccag
tttgtgcaccccatcttgcagagcgcagcgtga

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