KEGG   Phyllostomus discolor (pale spear-nosed bat): 114512580
Entry
114512580         CDS       T07739                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04064  NF-kappa B signaling pathway
pdic04072  Phospholipase D signaling pathway
pdic04151  PI3K-Akt signaling pathway
pdic04380  Osteoclast differentiation
pdic04611  Platelet activation
pdic04613  Neutrophil extracellular trap formation
pdic04625  C-type lectin receptor signaling pathway
pdic04650  Natural killer cell mediated cytotoxicity
pdic04662  B cell receptor signaling pathway
pdic04664  Fc epsilon RI signaling pathway
pdic04666  Fc gamma R-mediated phagocytosis
pdic05152  Tuberculosis
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05168  Herpes simplex virus 1 infection
pdic05169  Epstein-Barr virus infection
pdic05171  Coronavirus disease - COVID-19
pdic05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    114512580 (SYK)
   04072 Phospholipase D signaling pathway
    114512580 (SYK)
   04151 PI3K-Akt signaling pathway
    114512580 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    114512580 (SYK)
   04613 Neutrophil extracellular trap formation
    114512580 (SYK)
   04625 C-type lectin receptor signaling pathway
    114512580 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    114512580 (SYK)
   04662 B cell receptor signaling pathway
    114512580 (SYK)
   04664 Fc epsilon RI signaling pathway
    114512580 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    114512580 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114512580 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    114512580 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    114512580 (SYK)
   05168 Herpes simplex virus 1 infection
    114512580 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114512580 (SYK)
   05169 Epstein-Barr virus infection
    114512580 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    114512580 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114512580 (SYK)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     114512580 (SYK)
Protein kinases [BR:pdic01001]
 Non-receptor tyrosine kinases
  SYK family
   114512580 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 DUF7063 Kdo ABC1 RIO1 SH2_1
Other DBs
NCBI-GeneID: 114512580
NCBI-ProteinID: XP_028387311
UniProt: A0A6J2N621
LinkDB
Position
3:complement(128966299..129055904)
AA seq 627 aa
MASGVADHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY
TIERELNGTYAIAGGRAHASPAELCHYHSQESDGLICLLKKPFNRPPGVQPKTGPFEDLK
ENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLI
GSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLVEHY
SYKPDGLLRVLTVPCQKIGPPGNNPGCRPQLPSSHPATWSPGGIISRIKSYSFPKPGHRK
GASSQGTRPESSVTFNPYEPDRGSEREAHREALPMDTAVYESPYADPEEIRPKEVYLDRK
LLTLEDKELGSGNFGTVKKGYYQMKKGAKTVAVKILKNEANDPALKDELLAEANVMQQLD
NPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEEC
NFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK
FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYDLMNLC
WTYDVENRPGFAAVELRLRNYYYDVVN
NT seq 1884 nt   +upstreamnt  +downstreamnt
atggcctcaggtgtggctgaccacttgcccttcttctttggcaacatcacccgggaggag
gctgaggactacctggtccagggtggcatgagtgacgggctctacctgctgcgccagagc
cgcaattacctgggtggcttcgctctgtcagtggcacacgggcgcaaagcacaccactac
accattgagcgggagctgaatgggacctacgccatcgcgggtggcagggcacatgccagc
cctgctgagctctgccactaccactcccaagagtcagatggcctcatctgcctcctcaag
aagcctttcaaccggccacctggggtgcagcccaagactggacccttcgaggacctgaag
gagaaccttatccgggagtacgtgaagcagacctggaacctgcagggccaagctctggag
caggccattatcagccagaagcctcagctggagaagctgatcgccaccactgcccatgag
aaaatgccctggttccacggaaaaatctctcgggatgaatctgagcaaattgtcctgata
ggatcaaagacaaatggaaaatttttgatcagggccagggacaacaatgggtcctatgcc
ttgtgcctgctacatgagggcaaagtgctgcactaccgcatcgacaaggacaagacaggg
aagctctccatcccagacggcaagaagtttgacacgctctggcagctagtcgaacattat
tcttataaaccagatggtttgttaagagttcttacagttccatgtcaaaaaattgggcca
ccaggaaataatcctggatgtcgtccacaacttccaagttcccatccagcgacttggtca
ccgggtggaataatctcaagaatcaaatcatactccttcccaaagcctggccacagaaag
ggtgcctcatctcaggggacccggccagagagctccgtgacgttcaacccctatgagcca
gaccgaggctcagaaagagaagcccacagagaagccttgcccatggacacagcagtatat
gaaagcccctatgcagaccctgaggaaatcaggccgaaggaggtctacctagaccggaag
ctgctgaccctggaggacaaagaactaggctctggtaactttggcactgtgaagaagggc
tattaccaaatgaaaaaaggtgcaaaaacagtagcggtgaaaatcctgaaaaatgaggcc
aatgacccagctctgaaagatgaactgttagcagaagccaatgtcatgcagcagctagac
aacccttacattgtgcgtatgatcgggatctgtgaagctgagtcctggatgctggtcatg
gagatggcagaacttggtccactcaataaatatttacagcagaacaggcatgtgaaggat
aagaacatcatagagctggttcatcaggtttctatgggaatgaagtatttggaggagtgc
aattttgtgcatagagatctggctgcaagaaacgtattgctggttactcaacattatgcc
aagatcagtgattttggactttccaaagcacttcgtgctgatgaaaactactacaaggcc
cagacccatgggaagtggcccgtgaagtggtatgctccggaatgtatcaactactacaag
ttctccagcaaaagcgacgtctggagcttcggggtgttaatgtgggaagcattttcctat
gggcagaagccataccgggggatgaaaggaagtgaagtttctgctatgctggagaaagga
gagaggatggggtgccccccagggtgtccgagagagatgtatgatctgatgaacctgtgt
tggacatatgacgtcgagaacagacccggatttgcagcggtggaactgcggctgcgcaat
tactactatgacgtggtgaactaa

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