Phyllostomus discolor (pale spear-nosed bat): 114513194
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Entry
114513194 CDS
T07739
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00260
Glycine, serine and threonine metabolism
pdic00630
Glyoxylate and dicarboxylate metabolism
pdic00670
One carbon pool by folate
pdic01100
Metabolic pathways
pdic01200
Carbon metabolism
pdic01230
Biosynthesis of amino acids
pdic01240
Biosynthesis of cofactors
pdic01523
Antifolate resistance
pdic04981
Folate transport and metabolism
Module
pdic_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
114513194 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
114513194 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
114513194 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
114513194 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114513194 (SHMT2)
Enzymes [BR:
pdic01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
114513194 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
114513194
NCBI-ProteinID:
XP_028388193
UniProt:
A0A6J2NDB1
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Position
2:complement(160325262..160330257)
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AA seq
504 aa
AA seq
DB search
MLPFSLLWAPRPLQRYGQLIRMAIRCQHSEAAQTQNGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLAITARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAYLLADMAHISGLVAGKVIPSPFKHAEVVTTTTHKTLRGARSGLIFYRKGVRSVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQASTPMFREYSLQVLKNARA
MADALLDRGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVEFIDEGVKIGLEVKSKTAKLQDFKSFLLSDPETRQ
RLADLRQRVEQFARAFPMPGFDEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttttctttgctctgggcacctcggcctctgcagagatatggtcagctgatc
aggatggccatacgctgccagcacagtgaggcagcccagacccagaatggagaagcaacc
aggggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgcggcctggaactcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattatgggggagcagaggtagtggatgaaatcgagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgcacagtggggagtcaatgtccagcct
tattcggggtccccggctaatttggctgcctacacagcccttctgcagcctcacgaccga
atcatggggctggacctgcccgatgggggccatcttacccatggctatatgtctgatgtc
aagcggatttcggctacatccatcttctttgagtctatgccctacaaactgaacccccaa
actggcctcattgactatgaccagctggcaatcactgctcgacttttccgaccgaggctc
atcatagctggcaccagcgcctatgcccgcctcattgattatgcccgcatgagagaggtg
tgtgatgaggtcaaggcatacctgctggcggacatggcccacatcagtggcctggtggct
ggcaaagtgatcccctcacctttcaagcatgcagaggtcgtcaccactaccactcacaag
acccttcgaggggccaggtcaggactcatcttttaccggaaaggggtacggtctgtggac
cccaagactggccgggagatcccttatacatttgaggaccgaatcaactttgctgtgttc
ccgtccctgcaggggggcccccacaaccatgccatcgctgcagtggccgtggccctaaag
caggccagcacccccatgttccgggagtactccctgcaggttctgaagaacgctcgggcc
atggccgatgccctgttggatcgaggctactcgctggtgtctggtggcactgacaaccac
ctagtgctggtggacctacggcccaagggcctggacggggcacgggccgagcgggtgctg
gagcttgtgtccatcacggccaacaagaacacctgtcctggagatcgcagtgccatcacc
ccagggggccttcggctaggtgccccagccttgacctctcgacagtttcgtgaggatgac
ttccggagagttgtggagttcatagatgaaggggtcaaaattggtttggaggtgaagagc
aagactgccaaactgcaggatttcaaatccttcctgctcagtgacccagagacaagacag
cggctggctgacctcaggcaacgggtggaacagtttgccagggccttccccatgcctggc
tttgatgaacactga
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