KEGG   Phyllostomus discolor (pale spear-nosed bat): 114513223
Entry
114513223         CDS       T07739                                 
Symbol
TBK1
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04014  Ras signaling pathway
pdic04137  Mitophagy - animal
pdic04140  Autophagy - animal
pdic04620  Toll-like receptor signaling pathway
pdic04621  NOD-like receptor signaling pathway
pdic04622  RIG-I-like receptor signaling pathway
pdic04623  Cytosolic DNA-sensing pathway
pdic04657  IL-17 signaling pathway
pdic04936  Alcoholic liver disease
pdic05014  Amyotrophic lateral sclerosis
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05135  Yersinia infection
pdic05160  Hepatitis C
pdic05161  Hepatitis B
pdic05162  Measles
pdic05163  Human cytomegalovirus infection
pdic05164  Influenza A
pdic05165  Human papillomavirus infection
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05168  Herpes simplex virus 1 infection
pdic05169  Epstein-Barr virus infection
pdic05170  Human immunodeficiency virus 1 infection
pdic05171  Coronavirus disease - COVID-19
pdic05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    114513223 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114513223 (TBK1)
   04137 Mitophagy - animal
    114513223 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114513223 (TBK1)
   04621 NOD-like receptor signaling pathway
    114513223 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    114513223 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    114513223 (TBK1)
   04657 IL-17 signaling pathway
    114513223 (TBK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114513223 (TBK1)
   05161 Hepatitis B
    114513223 (TBK1)
   05160 Hepatitis C
    114513223 (TBK1)
   05171 Coronavirus disease - COVID-19
    114513223 (TBK1)
   05164 Influenza A
    114513223 (TBK1)
   05162 Measles
    114513223 (TBK1)
   05168 Herpes simplex virus 1 infection
    114513223 (TBK1)
   05163 Human cytomegalovirus infection
    114513223 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114513223 (TBK1)
   05169 Epstein-Barr virus infection
    114513223 (TBK1)
   05165 Human papillomavirus infection
    114513223 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    114513223 (TBK1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    114513223 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    114513223 (TBK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114513223 (TBK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114513223 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114513223 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pdic04131]
    114513223 (TBK1)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     114513223 (TBK1)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   114513223 (TBK1)
Membrane trafficking [BR:pdic04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    114513223 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 CEP63 DUF713 Kinase-like KIF21A COG6_N ubiquitin TPR_MLP1_2
Other DBs
NCBI-GeneID: 114513223
NCBI-ProteinID: XP_028388232
UniProt: A0A6J2N6S5
LinkDB
Position
2:complement(154877021..154931088)
AA seq 728 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSAEMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHDLVYKQTKITSSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSREPLSTIGLIYEKISLPKVQPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGMRWLIELVKDDYKQTVHKKTEVMITLNFCLRNIERTVK
PYEKLMKINLEAEVAEISDIRTKLLRLSSSQGTVETSLQDIESKLSPGGLLSDTWAHQEG
THPRDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHF
TDECVKKYETFLDKSEEWMRKMLHLRKQLSSLTKQCSDIGEEISKYQDYTNELQETLPQK
MFAASSGIKHTMASIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDG
GLRNVDCL
NT seq 2187 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacacaagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttcctccgtccagtagatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggagttttgtccatgcggaagcctatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggcatgaatcatctccgagagaatggcatagtgcatcgcgatatcaagccaggaaat
atcatgcgtgttataggggaagacggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctttatatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctgagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaactttttaccatgcagccactggatcactacca
tttagaccattcgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
gcagaaatgcctgtttcttgtagtctttctcggggtcttcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgacttggtgtat
aaacaaaccaaaattacttcttcaaatcaagaacttatatatgaaggacgacgcttagtt
ctagaacctgggagactagcacagcatttccctaaaactactgaggaaaaccctatcttt
gtagtaagccgggaacctctgagtaccataggattgatatatgaaaaaatttccctccct
aaagtgcagccacgttatgatttagatggagatgctagcatggctaaggcaataacagga
gttgtgtgttacgcctgtagaattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatgcgatggttgatagaattagttaaagatgattataagcaaacagtgcacaaa
aagacagaagttatgatcacattgaatttctgcctcagaaatattgaaagaactgtgaaa
ccatatgaaaaattgatgaaaatcaacctagaagcagaagtagctgaaatttcagacata
cgcaccaaattgttgagactctccagttctcagggaacagtagaaaccagccttcaggat
atcgaaagcaaattgtctccaggcgggctgttgtcggatacatgggcccatcaagaaggc
actcatccaagagacagacatgtagaaaagctacaagtcctgttaaattgcatcacagag
atttactatcagttcaaaaaagacaaagcagaacgcagactagcttataatgaagaacaa
atccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccacttt
acagatgaatgtgttaaaaagtacgagacatttttggataaatcagaagaatggatgaga
aagatgcttcatcttaggaaacagttatcatccctaactaaacagtgttctgatattgga
gaagaaatatcaaagtatcaagactatactaatgagttacaggaaactttgcctcagaaa
atgtttgcagcttccagtggaatcaaacatacgatggcttcaatttatccatgttctaac
acattagtagaaatgactcttggtatgaagaaattaaaagaagaaatggaaggggtggtt
aaagaacttgctgaaaataaccatattttagaaaggtttggctctttaaccatggatggt
ggccttcgcaatgttgactgtctttag

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