KEGG   Phyllostomus discolor (pale spear-nosed bat): 114513352
Entry
114513352         CDS       T07739                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00480  Glutathione metabolism
pdic00980  Metabolism of xenobiotics by cytochrome P450
pdic00982  Drug metabolism - cytochrome P450
pdic00983  Drug metabolism - other enzymes
pdic01100  Metabolic pathways
pdic01524  Platinum drug resistance
pdic05200  Pathways in cancer
pdic05204  Chemical carcinogenesis - DNA adducts
pdic05207  Chemical carcinogenesis - receptor activation
pdic05208  Chemical carcinogenesis - reactive oxygen species
pdic05225  Hepatocellular carcinoma
pdic05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    114513352 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    114513352 (MGST1)
   00982 Drug metabolism - cytochrome P450
    114513352 (MGST1)
   00983 Drug metabolism - other enzymes
    114513352 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114513352 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    114513352 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    114513352 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    114513352 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    114513352 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    114513352 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    114513352 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pdic02000]
    114513352 (MGST1)
Enzymes [BR:pdic01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     114513352 (MGST1)
Transporters [BR:pdic02000]
 Other transporters
  Pores ion channels [TC:1]
   114513352 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 114513352
NCBI-ProteinID: XP_028388451
UniProt: A0A6J2N961
LinkDB
Position
2:complement(187338102..187359776)
AA seq 155 aa
MVGITQLMEDKVLMAFASYATIVLSKMMFMSTATSFYRLTRKVFVNPEDCASFGKGENAK
KYLRVDDTVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTAILHFRVFVGARIYHTIA
YLLPLPQPNRALAFFVGYGVTISMAYRLLTSRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggttggcattacccagctaatggaagataaagttctcatggcctttgcttcctatgct
acaattgttctttccaaaatgatgtttatgagtactgcaacttcattctacagattgaca
agaaaggtttttgtcaacccagaagactgcgcaagctttggcaaaggagaaaatgccaag
aaataccttcgggtagatgacacagtagaacgtgtgcgaagggcccatctgaatgacctt
gagaatattgtgccatttcttggcattggccttctgtattccttaagcggtccagacctc
tcaacagccatcctgcacttcagagtcttcgtgggagctcggatctaccacacaatagca
tatctgttacccctcccccagccgaatcgtgctctggctttttttgttggatatggagtt
actatttcaatggcttaccggttgctgacaagtagattgtacctatga

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