Phyllostomus discolor (pale spear-nosed bat): 114515202
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Entry
114515202 CDS
T07739
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00260
Glycine, serine and threonine metabolism
pdic00630
Glyoxylate and dicarboxylate metabolism
pdic00670
One carbon pool by folate
pdic01100
Metabolic pathways
pdic01200
Carbon metabolism
pdic01230
Biosynthesis of amino acids
pdic01240
Biosynthesis of cofactors
pdic01523
Antifolate resistance
pdic04981
Folate transport and metabolism
Module
pdic_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
114515202 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
114515202 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
114515202 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
114515202 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114515202 (SHMT1)
Enzymes [BR:
pdic01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
114515202 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
114515202
NCBI-ProteinID:
XP_028390339
UniProt:
A0A6J2NEX9
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Position
8:complement(61497590..61518831)
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AA seq
484 aa
AA seq
DB search
MATEVNGAPKDADLWHSHNKMLAQPLKDNDIEVYNIIKKESKRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFDHCHVVSTTTHKTLRGCRAGMIFYRRGVCGVDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQALTPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQK
VALFIHKGIELTLQIQNDVGVKATLKEFKEKLVGDEKHLSSIRALREEVESFASLFPLPG
LLDA
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactgaggtcaacggggctcccaaggatgctgacctgtggcactcgcacaataaa
atgctggcacagccgctgaaggacaacgacatagaggtttacaacatcattaagaaggaa
agcaaacggcagagggttggattagagctgatcgcctcagagaattttgccagcagagca
gttttggaggccctgggctcttgcctaaataacaagtactctgaggggtacccaggccag
aggtattatggtggcactgagttcatcgatgagctggagaccctctgtcagaagcgagcc
ctgcaggtctatggtctggacccccagtgctggggagtcaacgtccagccctactcaggg
tcccctgccaacttcgcagtgtacaccgccctggtggaaccccatggacgcatcatgggc
ctggacctgcccgatggaggccatctgacccacgggttcatgacagataagaagaaaatc
tctgctacgtccatcttttttgaatctatgccctacaaggtgaacccagacactggctac
atcaactatgaccagctggaggagaacgcccgcctcttccacccgaagctgattattgca
ggaaccagctgctactcccgaaacctggattacgctcgattgcggaagattgccgatgac
aatggggcatatctcatggctgacatggcacacatcagcgggctggtggcggctggcgtg
gtgccctccccctttgaccactgccatgtggtgtccaccaccacccacaaaaccctgaga
ggctgccgggctggcatgatcttctacaggcgaggagtgtgcggcgtggatcccaaaact
ggcaaagagatcctgtacaacctggagtcgctcatcaattctgctgtgttcccaggactg
cagggaggcccccacaaccacgccattgctggggtcgccgtggctctgaagcaagccctg
actccagaattcagactttatcagcaccaggtggtggccaactgcagggttctggctgag
actttaatggaactgggctacaaagtagtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacggatggtggcagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggtgacaaaagcgcactgaggcccagtggg
ctgcgactggggaccccagcactgacgtcccgtggacttctggaaaaagagttccaaaaa
gtagccctcttcattcataaagggatagaactgactctgcagattcagaacgacgttggt
gtcaaggccaccctgaaggagttcaaggagaaactggtaggggatgagaagcaccttagc
agcatcagagctctcagggaggaggtagagagctttgcatctcttttccctctgcctggc
ctgcttgatgcctag
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