Parascardovia denticolens: PSDT_0634
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Entry
PSDT_0634 CDS
T03978
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pdo
Parascardovia denticolens
Pathway
pdo00550
Peptidoglycan biosynthesis
pdo01100
Metabolic pathways
pdo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pdo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PSDT_0634
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PSDT_0634
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PSDT_0634
Enzymes [BR:
pdo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PSDT_0634
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAR05153
UniProt:
E6JZB6
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All DBs
Position
763854..765431
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AA seq
525 aa
AA seq
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MISMTLAETAQAMSGKLLVFESASASIDSQAQVDSAVTDSRQVRPGSLFVAIKGERVDGH
AYLEQAAAAGAVAAVVDHEVAGASLPQILVEDTVRALGFLARHNIEKRRSLAGQARTPFT
IVGITGSVGKTTTKDLIRALLSPLGPTIAPQGSFNNEIGLPLTALQVGEETRFLVAEMGA
SAVGEIAYLTTIARPDLAVELKVGVAHLGGFGSVENIRQAKSELVRALPPSGLAILNEND
ENIRLMPEMTGVRNLLWFGLHEDRPDEDRSDESETAYPSVPSAMSAAEIYGDQVQVDDQD
RPSFTVHFPDGTGCPMSLALPGRHNVMNALAAICVAYAMDLPTEAIAGILAHQGAQSPHR
MDIRQVPFRPDSDLAFTLIDDSFNANPDSMKAGLDGLAAWHAESRTRDERPYRVAVLGSM
LELGPNEKELHQRMGAYALSVADMVIAVGSEEEPHLDELAHDFVLGADHDQKEAGSIHWV
HSAEQAADLVRGLEGEHRQTVVLLKGSHASGLQGLADYWLGQARK
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgatttccatgaccctggccgagaccgctcaggccatgtcaggcaagctcctcgttttc
gagtccgcttccgcttccatcgatagtcaggcccaggtcgattccgccgtgaccgattcc
cggcaggtccgccctggctccctcttcgtggccatcaaaggggaacgcgtggacgggcat
gcctatctggagcaggcggccgctgcgggggccgtcgccgccgtggtcgatcatgaagtc
gccggggcctccttgcctcagattctggtggaggacacggtccgcgctttgggctttctg
gcccgtcataacatcgaaaaacgccggagcctggccggccaggctaggacccccttcacc
atcgtcggcatcaccggttcggtgggcaagaccacgaccaaagacctgatccgcgccttg
ctgtcccccttggggccgacgatcgccccccagggttccttcaacaacgagatcggcctg
cccctcaccgccttgcaggtgggggaggagacccgtttcctggtggcggagatgggggct
tcagccgttggggaaatcgcatacttgaccaccatcgcccggccggacctagccgtcgag
ctgaaggtgggggtggcccatctgggtggattcggttccgtggagaacatccgccaggcc
aagagcgagctggtgagggccttgcccccctccggcctggccatcctcaacgagaacgac
gagaacatccgcctgatgccggagatgaccggggtcaggaacctcctttggttcggtctg
cacgaggaccgccccgatgaggaccgctctgatgagagcgagaccgcttatccctcggtc
ccctccgccatgtccgccgccgagatctacggcgaccaggtgcaggtggatgaccaggac
cgcccgtccttcaccgtccatttccctgacgggactggctgccccatgagcctggctttg
ccggggcggcacaacgtcatgaacgccttggccgccatctgcgtggcctacgccatggac
ctgcccaccgaggccatcgcaggtatcctggcccatcaaggggcccagagcccccatcgc
atggacatcaggcaggtgcccttccgtccggattccgacctggccttcaccctcatcgat
gactccttcaacgctaaccccgattccatgaaggcgggcttggacggcttggccgcctgg
catgctgaaagccggacccgggacgagcgcccctaccgggtggccgtactgggctccatg
ctggagttgggccccaacgagaaggagctccatcagcggatgggggcctacgccctttcc
gtcgccgacatggtgatcgccgtcggcagcgaggaggagccccatctggacgagctggcc
catgacttcgttctcggagccgaccatgaccaaaaagaggccgggtccatccactgggtc
cattcggccgagcaggcggccgacctggtcaggggtttggaaggggagcataggcagact
gtagtattgttgaaagggtcccacgcgtccggtttgcaagggctagcggattactggctg
ggacaggcacggaagtag
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