Penicillium digitatum: PDIP_33160 Help Entry PDIP_33160        CDS       T04849                                  Name (RefSeq) TOM1, putative   KO K10592   E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26] Organism pdp  Penicillium digitatum Pathway pdp04120   Ubiquitin mediated proteolysis Brite KEGG Orthology (KO) [BR:pdp00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     PDIP_33160  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pdp04121]     PDIP_33160 Enzymes [BR:pdp01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.26  HECT-type E3 ubiquitin transferase      PDIP_33160 Ubiquitin system [BR:pdp04121]  Ubiquitin ligases (E3)   HECT type E3    PDIP_33160 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DUF913 DUF908 HECT Pribosyltran_N Pribosyl_synth UBM Pribosyltran UPRTase Motif Other DBs NCBI-GeneID:  26231636 NCBI-ProteinID:  XP_014535920 UniProt:  K9G7Y9 LinkDB All DBs Position Unknown AA seq 4378 aa AA seqDB search MGRIKKVASQKHEATISPFLQEFIARATSLPVPELPSLLNTFPKLWPFPRGDLYHWINVL DRFDEILASAVEKYFLNTGPQTQLFTRNVLEESYSADESKKPAEGVDAKLNALGYGPEGD RELVEAVLDFSRLLLEKCGNRSLYSSSDRLGDLLNTTSLSLLQSTLRLSLCLAQRYHSRQ RGTHQQSVLQSHYALDLEKLQKIAAPFPRPVITSKTPFAASPAGLTKGKENTAHTKIDAN ELVSLVRDGDGWEEWGDVRVLYYPSGSEQTRTTSEFGQTEQGFHIPTTPTPLRRSATHPA PHSNQGSNGDESPAVTGGKAEEATRAGKVLELPYSKVSTAKVEDLLAANLPHLPLESKYE LLQKLRVAKALTASRATREQILSIKALAVTNLAHVQPESTFQSKVLQSDLEQPKRLQLAY QLAEVVHLGASGDLEVSRSVQTLAIQALDALAKHKARAVDVCAALSVNVNHGILMFLTRK MVNELGPENNDPDDAYYDEWRDALLALLRTLPSSSTRTPETLVAAGLIPMFVDILKLRTE KSRRVYSRIMEFLDTFVHAVRDALGTLTTAKGFDAMSDLIDHETKTAFEKVNRGDGFPAQ YKNPSIDYQIPYFQQQTLRWMFRFVNHIMQHNGGGFDRVLRNLIDSPQLLTSLRLVFENA RVFGSHVWSNAVNILSSFIHNEPTSYAVIAEAGLSKSLLAAVMGRELKVLEKPPAVELED RETEIEIEAEPAATQPPSAEAATQSEEKQKGREYAIVRPQNTPLASGIMPAADALACIPG AFGAICLNSSGLDLFQSSDALESFFEIFENPEHVKCLKDDSDLVRSLGTTFDELVRHHPA LKTSIMSAVLVMAARVNILGRVKAWELGMGTRMWTQDADGKTTLLGDVFSLFREIGTAID APTDDPASFGAPKLNANTLPNGAKLVVGDLDHVLPSPGPDFEPKDKDSHGLSATDYLFPA LRFLSAFFDNQTNCTSFILAGGTEFLLDLATLQSLAFDFHSTNANQEITVLVHMLAETKP HLVVPSLVRRAQAAVDNLSAFWTAPTGSGFFTELIKPADSKKPAPETTAAAKSGTFFVRH LNAVLLLTDVLREVFASPQYQTRPGQSTSIFGQANLADHYCSLISSLSNLLASCVWEGIL LEKNIPDKWLKATQASAEKHGSGKSKVVAVTGNTQEPSATPGAESQQESTGALETAPAQS GLGPTEDDAEVDEQCSAFKNARTLRYLLSALPTSITGFLHNLGLGMIGKRRTDPLQKQKA NAILVSDAIAEGILRQLQFNPANSSNSTKHRFAYLIVILSHFSHLLYEVSADRPSPNYLT SVLVSFNKINGLRVLKDICDVFLGDIKSLPSAESIPDQDKELADRLASGYGGIKIILGLF ADLTAGKFIVDSSQTQALTSHPERDRDRPDYFQPGQLLVDLRMEILPLAKDMWNSDFATQ SSSPIVRLLIDIMRCSLDGEYETGAARKVDTPPILVEMPKKPFVVHTERATALLEKGSGY EPPPRVPPAPGDIKTGLPESASGIESLEDAGLGEVQPFNSANPLDRSAALQMLLARAAGR PVADAMRRSPFPGGDIDYDMHDGLGRALENVLNDNDDMDSDDRGELSNQRRLESRNPGAS SSELTGASQGESVKRRHMVTIEDLDAERQNIRSNLIDRALDILNEHHDVSFELSDLITSA IKKHSEPVNFRRDIGETLVQSLVSLQMENFQTAGKKIAAYAHILALTLQDHDMYLATLEE LKDCFSTFLGFIKLPTPEKADQETFPWVGHVLLILEKLLSDDCQPPKIAWTMPSLDDPNP SGDEPARLEDPLISLEEKTRLFEALVEILPRVGKDDTLALSMCRVLVILTRERSIAARFG EKRNLQRLFVMVKQLSSATNEKLQSAFMLILRHIVEDESTIRQIMRSEIVANFESKTTRQ IDTNGYVRHLYHLVLRAPDIFVEVTNEKLRLLRYDNQRPQVLGLKADKDRQQKRGRPSIF LEEHKPESSAAGEASALEDTDKSKEDKGKTQTKGAELKAPIVENPDGVIHYLLSELLSYK DVDDKEAGPEFPEQSTDQSDTQTDVEMTADEPTPSISSTTEAHASRGSKKAEKPQFKADD HPIYIYRCLLLQCLTELLSSYNRTKVEFINFSRKADPLATTPSKPRSGVLNYLLNVLVPL GTMDHDESLAFKKRSITSTWTMQVLVALCTKTGEFGGVGRRRTEPKYEDDEPELAFVRRF VLEHALRSYKDAMASIEPLDVKYSKLMSLADLFDKMLSGYSFTNDAGFPTSTRQLAKTMF EKNFIPALTSSVADVDLNFPSSRRVIKYILRPLNKLTQTAVLLSENSDIPIQGDNEDDEI SSATSVSDMEDEREETPDLFRHSTLGMLEPRHDEEESSTEESEGEDDEMYDDEYDEEMDY DEDVAEDDGEVVSDEDDDGMGPIEGLSGDAVEVILDEDDDEDEDDDDEDHDHSDMHDDMY DGEIGGDRDNESLEDDEEDEWESEEMTEDEEEVEMMNQFEDEMADIRQSNRQQGEDQHLG DLFRALNGSGVDDIHGDALGGDIHEEILDDLDEDGLYFLRLLRQLPAPLPQPALLTSAPV EDEDEMDELDEDMDDFDEEQGSYGDMEGESDSVNDFLTSLLTRPEDDDLLEPWGWEGDEP PVARGHPQSRFRGGPSPAWATVTEIMPGRQSGLVPIQPYHRVHRTQIPSRGNDDGINPLL VRTDRPDAAVQPRTAADPFADWGQSMDTAAGRVIAMDSPISFMNAIMQAIGGQAASGFGV VTRPDGIHVHVDRRAVLPGRIQDMLGIPRGAGPPTRTRGDDPHTAVKFGLGTTRNRWQEE ARIIFGNQHVERTIRIINSILRLLVPPAIEEEKQRQKLAEEERKRLQAERAEKERQDRIA AEEKQRELKQKEEEENARLQAEKDQREAERQAAGVDEPMEDVPETDTAVETAGPSTQPEA QPTEPSRRVYTNIRGRQVDITGLEIDSEYLEALPEELREEVIMQQLAEHRSQAAAAGEED TEINQEFLEALPAEIREELLQQEAADRRRRERETARRQAAAGAGAGATASSTQPAEEMDA VSFLATLDPSLRQAVLADQPEDVLATLGPEYMTEARGMGGSGRRMAQFGDMSAVDHRQRI EPAAGQEPKKEQRRQIVQMLDKAGVATLLRLMFMPLQGNARHQLNDILHNVCENRQNRSE VISVLLSILQDGSIDSTAIERSFSHLSLRAKAPGTQKTPQSKRTLAIQTASSVSSEVTPI MVIQQCIAALSFLSQFNPHIAWFFLTEHDSASAGKLKSLRKGKGKENRANKFALNALLSL LDRKLIMESPNCMEQLSSLLSSITQPLTVLLRREKERQEESKGKKPERPEIEASTDQLAE AADSSMDTSMTDALLPTVEIPGAPGQETVESEEATSAEAKKSEDFKEPAEDEKRKKRTIE PPVIPDHNLRLVVHILAARECNGKTFRDTLSTINNLSAIPGARDVIGNELVAQAQALSDT ILGDLEDLLPHIHQAKTGTDMQGLALAKFSPASSDQAKLLRILTALDYLFDHARADKSRD LEPGSAPKEDVLKKLYESATFGPLWSKLSDCLTVIRQKENMLNVATILLPLIEALMVVCK NTTLKDQPLSRGSRELSVNSTATADAGLSMENIFFRFTEEHRKILNELVRQNPRLMSGTF SLLVKNPKVLEFDNKRNYFTRRVHSRGAEPRHPHPPLQLSVRRAEVFLDSFKSLYFKSAD ELKYGKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVAADRTTFHPNRLSGV NSEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKNILGRSVSIKDMETLDLDYYKSLLW MLENDITDIITETFSIETDDFGEKQVIDLKPGGHDIPVTQENKEEYVQRVVEYRLVGSVR EQLDNFLKGFHEIIPPELISIFNEQELELLISGLPEIDVDEWKNHTEYHNYSASSSQIQW FWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELEGMNGVSKFNIHRDYGHKDRLPSSHT CFNQLDLPEYESYEDLRQRLYTAVTAGSEYFGFERLFIMSANSIKLLTGNSHPELANLVA DRLGIELTKIMVLQYSNQETSVTIGESVRDEDVFILQSTKPNDINDGLMELLIMINACKT ASARRITAVIPNFPYARQDKKDKSRAPITAKLMANMLQTAGCNHVITMDLHASQIQGFFN VPVDNLYAEPSMLKYIRENLDVSNCVIVSPDAGGAKRATAIADRLDLQFALIHKERARPN EVSRMVLVGNVKDKVAIIVDDMADTCGTLAKAAETVMQHGATEVNAIVVHGILSGKAIEN LNGSCLKRIIVSNTVPLGDKQEQCDKIHTIDISPTLAEACRRTHNGESVSFLFSHTVG NT seq 13137 nt NT seq  +upstreamnt  +downstreamnt atggggagaattaagaaggtagccagccaaaagcatgaggctacaatctcaccttttttg caagaatttatagcgcgtgccacaagtcttcccgttccagagctcccttcgcttctcaac acattccctaagctatggccgttcccacgcggcgatctctaccattggatcaacgtccta gaccgattcgacgagattctggcctcagccgtggagaaatactttttgaacactggccct cagactcagctgttcacccgaaatgttttggaggaatcatactcggccgacgagagcaag aagccagcagagggggttgatgctaaactaaacgctctggggtacggccctgaaggagat agagagcttgtggaagcagttcttgatttctctcgtcttttgctcgagaaatgtggaaac cgcagcctgtacagcagcagcgatcgcctgggtgacctgttgaataccacctcactctct ctcctacaatctacattgcgactgtctctttgcttagcccaacgataccactctcgccag cgtggcacccatcagcagtctgtattgcaatcccactatgctcttgatctcgaaaagttg cagaagattgcagcacctttcccgcgcccagtcatcaccagtaaaacaccgtttgccgca tctcccgccggtttaaccaaggggaaggaaaatacagcccataccaaaatcgacgccaat gaactggtttccctcgtgcgtgatggcgatggctgggaggaatggggagatgtccgagtt ctctactatccctcgggctccgaacagactagaacaacctctgaattcggccaaacagag cagggcttccatattccaactacgccaaccccattgcgacgcagtgcgacacaccccgct cctcattctaaccagggctcaaatggcgatgaatcaccagctgtcactggtgggaaggca gaggaggccacgcgagcgggcaaagtcctagagctcccctactcaaaagtttcaactgca aaagtggaagatcttcttgcagccaacttgcctcatctgcccctcgaatcaaaatatgag ctgcttcaaaaactccgagttgccaaggcgttgacagcgtcgcgtgccacgcgagaacag atcctttccatcaaggcactggcagtgaccaacctggctcatgtccagccggagagtact tttcagtcaaaggttcttcaatctgatctggaacaaccgaagcgtcttcagcttgcttac cagcttgctgaagtggttcatctcggtgccagtggtgatctcgaggtctcccggtctgtc caaaccttggcgatccaggcactggatgcgttggctaagcacaaggctcgtgctgttgac gtctgtgcagctttgagcgtcaacgtcaaccacggaattctcatgtttttgacccgtaaa atggtcaatgaactaggccctgagaacaacgatccggatgatgcctactacgatgaatgg cgagatgctttgcttgcactcctacgcactctcccaagctcgagcacacgtacaccagag accttggttgcagcgggtctgattcccatgtttgttgatattttgaaactgcggactgaa aaatcccgccgagtctactcccgcatcatggagttccttgacacatttgtgcatgcggtc cgggatgcactaggtacactgacaacagcgaagggatttgacgccatgtctgatttgatt gatcacgagacgaagaccgcatttgagaaggtcaaccgaggggatggattccccgctcaa tacaagaacccttcaattgactatcaaatcccttactttcagcagcagacactgcgttgg atgttccgttttgtcaatcatatcatgcagcacaatggcggaggattcgatcgtgttttg agaaacttgatagattcgcctcagctgttaacttctcttcgccttgtgttcgagaatgct cgcgtgttcggttcacatgtgtggagcaatgctgtcaacattctcagcagcttcattcac aacgaacctactagctatgctgttatcgctgaggctggcctcagcaagagtcttcttgct gcagtcatggggcgtgaactgaaggtgttggagaagccgccggccgtggaacttgaagac cgggagactgagattgagatcgaggccgaacctgccgctactcaaccccccagcgccgaa gctgccacccagtccgaggaaaagcaaaaaggtcgcgagtacgctatcgttagaccccag aacacccctctcgcatctggcataatgcccgcagctgatgctcttgcttgtatccctggt gcatttggggccatctgcttgaactcttccggtttggatctcttccagtcctccgatgcg ctggaaagcttcttcgagatcttcgagaaccctgagcatgtcaagtgtctgaaggatgac tcggatctggttcgttcgttaggcaccacctttgatgagctggtccgacaccacccggca ttgaaaacctcgatcatgtctgctgttcttgtgatggctgctcgtgtcaacatcctgggg cgagtcaaggcatgggagcttggtatgggcacaaggatgtggactcaagatgccgacggt aagacaacccttttaggagatgtcttttcattgttccgagagatcggcacagccattgat gcacccacagacgaccctgcttcgtttggtgcccccaagcttaacgcgaacactcttcct aacggcgccaagcttgttgttggggatctggatcatgttcttccttctccaggccccgac ttcgagcctaaagataaagattcccacggtctttccgctacggactacctgttcccagct ttgcgattcctgagcgctttcttcgacaaccagacgaattgcacatccttcatcctggcc ggcggcacagagttcttgttggatcttgcaacactccagagcttggcgtttgatttccac agcactaatgccaaccaagagatcactgtacttgttcacatgctcgcggaaacgaaacct caccttgtggtcccttctctcgttcgacgcgcacaggcagcagtggataatctttcggca ttttggactgcgcccaccggatcgggattctttaccgaattgattaagcctgcagactcg aaaaaaccagctcctgagactacggcggctgctaaatctggcacattcttcgtgaggcac ttgaatgccgttctactcctcaccgacgtccttcgcgaggttttcgcatcgccacagtac caaactcgacccggtcaatctacctccatcttcggccaagctaatcttgctgaccattac tgttccctaatctcctcactgagcaaccttcttgcctcttgcgtgtgggaaggaattttg ctggagaagaacatccctgacaagtggctgaaagcgacacaggcctctgctgaaaagcat ggctctggaaagtcaaaggttgtcgcggttaccgggaacacacaggagccttcagcgact cctggcgccgaatctcaacaggagagcactggtgcactagagactgctccggctcagtcg ggccttggcccgacagaagacgacgctgaagttgatgaacagtgctctgctttcaagaat gcgcgtactctccgctaccttctaagcgctctaccaacatcaattacgggtttcttgcac aacctcggactcggtatgatcggcaagagacgcacagatcccctccagaaacagaaggcg aatgctatcttggtctcagacgccattgctgaaggcattcttcgccaactgcagttcaac cctgccaattcgagtaacagcaccaagcaccggtttgcatatctcatagtcattctttcc cacttctcgcaccttctctatgaagtctcagcagaccgtcccagtccgaactacttgact tcagttctcgtttcattcaataaaatcaacggtctcagagtgttgaaggatatctgtgac gtcttcttaggcgacattaagtcccttccatccgcggagtccattccagaccaggacaaa gagcttgccgaccggcttgcatccgggtatggtggaattaagatcattcttgggttattc gcagacctcactgctgggaaattcattgtggactctagccagacacaagccttgacctct caccctgaacgggatcgagaccgtcccgattacttccagccaggtcaacttttggtggat cttcgtatggagattttgcccctggctaaagacatgtggaactcagactttgcgactcag tcatcgagtccaattgtccggttgttgattgacattatgcggtgctcactggatggcgaa tacgagactggcgcggctcgcaaagtagataccccgcccatcttggttgagatgcctaaa aagccattcgttgtccacacggaacgagcaactgctttgctcgagaaaggcagtggctac gagcccccccccagagtacccccggctcccggcgatatcaaaactggactacccgagtct gcttctggcatcgaatccctcgaggatgccggtcttggagaggttcaacctttcaatagc gccaatccgttggaccgctctgcagcactccaaatgcttctggctcgagcagctggacga cccgtagctgacgcaatgcgccgctctcctttccccggaggcgatattgattacgacatg cacgacgggttgggtagagctctagagaacgttctcaacgacaatgatgacatggatagc gatgaccggggcgaattatcgaatcagcgtcggctcgagagtcgtaatcccggggcaagc tcttctgaacttaccggagcctctcagggagaatcagtcaaacgtcgccatatggtcaca attgaggacctggatgcagagaggcaaaacattcggtcaaacctgatcgaccgggccctt gacatcctaaacgaacaccatgacgtctctttcgagctatctgacttgatcacctcggcc atcaagaagcatagcgagcctgtcaacttccgtcgagacattggagagacccttgttcaa tcgctagtatctctgcagatggagaacttccagacagctggcaaaaaaatcgcggcttat gcacacattcttgcgctgaccctccaagatcatgacatgtacctcgccactcttgaggag ctcaaagattgcttctcgactttccttggatttatcaagctcccaacacctgaaaaggcc gaccaagagaccttcccctgggttggacatgtcctgcttattctcgagaagctgctgtct gatgattgtcagcctcccaagattgcctggaccatgccaagtcttgatgatccaaatccc agcggcgatgagccagcccgtcttgaagatccccttatctcactcgaagagaaaaccagg ctatttgaagctcttgtcgagatactaccgcgagtgggcaaggacgatacactggccctc tccatgtgccgtgttcttgtcattctcacccgcgagcgcagcattgccgcccgctttgga gaaaagcgaaatcttcagcgtttgtttgttatggttaagcaactttccagtgctacaaat gagaaactccaaagcgccttcatgctgatacttcgtcacatcgtcgaggacgaatccact attcggcagatcatgaggagtgaaatcgttgctaactttgagtccaagaccacccgtcag attgacacaaacggctatgtacgacatttgtatcacctcgtgctaagagctcctgatatc tttgtggaggtcacaaatgaaaagctgcggttgctccgatatgataatcaacgtccacaa gttcttggattgaaggccgacaaagatcggcaacaaaagcgaggaaggcccagtattttc ctcgaagagcacaagccagaatcgtctgcagcaggcgaagcgtctgccctcgaagacacg gacaagagcaaggaggacaagggcaagactcaaaccaagggggccgagctcaaagcccca attgtggagaacccggatggcgttattcattatctcctttcggagcttctgtcctacaaa gatgtggacgacaaagaagccggtcctgaattcccagagcagtcaactgaccaatccgat actcaaactgatgttgagatgaccgcggatgagccaacaccttcaatatcgagtactacc gaagcacatgcatctcgcggctccaagaaggcagagaagccccaattcaaggcagatgac catccgatttacatctatcgctgcttgctccttcagtgcttgacggaacttctttcctct tacaaccggaccaaggtcgagttcatcaacttttcccgcaaggctgatcctctggccacc actccctccaaaccgcgctctggcgtcttgaactatttgttgaatgtgcttgttcccctt ggtactatggatcatgacgagtctttggcgttcaaaaaacgcagtatcacctccacatgg accatgcaagtgcttgttgcactttgcactaagaccggcgagtttggtggtgttggtaga cgtcgcactgagccaaaatatgaggatgatgagcctgagcttgcctttgtccgtcgtttc gtgctggagcatgctctccggtcctacaaagatgctatggcctctatcgaacccctagat gtcaagtattccaagctcatgtcgcttgctgatctcttcgacaaaatgctcagcggctat tccttcaccaacgacgcgggcttcccaacttcaaccaggcagctcgcgaagaccatgttc gaaaagaacttcatccccgccctcacttcttcagtcgctgatgtcgacttgaatttcccg tcctccaggcgtgtcattaagtatattcttcgtccattgaataaacttacccagactgcc gtgcttctcagcgagaactcggacatccccatccaaggtgataatgaggatgatgagatc tcgtccgcaacttccgtttctgacatggaagatgaacgtgaagaaacacctgacctcttc cgccactctacccttggtatgctagagcctcgtcatgacgaggaagagagcagcaccgaa gaatcggagggtgaggacgatgagatgtatgatgatgagtacgacgaagaaatggactac gacgaggatgtcgctgaagatgatggtgaagtcgtcagcgacgaagacgacgatggcatg ggtccaatcgaaggtctttccggagatgcagtcgaagtcatcctcgacgaagatgatgac gaagacgaggacgatgacgatgaagatcacgaccactcggacatgcatgatgatatgtat gacggagaaattggcggtgaccgagacaacgaaagcctcgaagatgacgaagaggacgaa tgggaaagcgaagaaatgactgaagacgaagaggaggtcgaaatgatgaaccaattcgaa gatgaaatggccgatatcagacaatccaacagacaacaaggtgaagaccagcatcttggc gacctattccgtgctctcaatggttctggtgttgatgatatccatggagatgccctaggt ggtgacattcacgaagaaattcttgatgacctcgatgaagatggtttgtatttccttaga ctgctgaggcagctcccagcgcccctgccacagccagccttactgacatctgctccagtt gaagacgaagacgaaatggatgaacttgacgaggacatggatgatttcgacgaagaacaa ggatcttatggggatatggaaggtgagtccgactctgtcaatgattttctcacatcgttg ttgactcgcccagaagacgatgatcttcttgagccatggggatgggaaggcgatgaacct ccagtggcccgaggacatcctcaatcccgcttccgcggaggcccgtcaccagcctgggct accgttactgaaatcatgccgggtcgccaatccggtcttgttcccatccagccttaccac cgtgttcaccgaacccaaatcccatcccgcggcaacgacgatggcattaatcctcttctt gtccggactgaccgcccagatgccgccgtccaacctcggaccgctgctgatcctttcgcc gattggggccaatctatggacactgcagctggccgggttattgctatggatagccccatt agcttcatgaatgcaattatgcaagccatcggcggacaggccgcgtcaggtttcggcgta gtcactcgccctgatggtattcatgtacatgtcgaccgacgagcagtcttgcctggtcgt atccaggatatgcttggaattccccgaggagcaggtcctccaacccgcacacgcggcgac gaccctcacactgccgtcaagtttggtcttggtaccaccagaaaccgctggcaagaagag gcccgcataattttcggcaaccagcatgttgagcggaccatacgcatcatcaactctatt ctcaggctcttggttccccctgccattgaggaggagaagcagcgccagaagcttgcagaa gaggaacgcaaacgtcttcaagccgaaagagctgaaaaggaacgccaagatcgcattgcc gctgaagaaaaacagcgtgagcttaagcaaaaggaggaggaagaaaacgcccgattacag gcagagaaagaccaacgtgaagccgagcgccaggctgctggggtcgatgagcccatggaa gatgtcccggaaaccgatactgcggttgaaaccgctggcccatctactcaacctgaagcc cagcccactgaaccttctcgtcgagtctacacgaacatcagaggccgccaagttgatatc accggtcttgagattgattcggagtatctggaggctctgcctgaggaactccgggaggaa gtcatcatgcaacagcttgctgaacatcgatctcaggctgccgctgcgggtgaagaggat actgagataaaccaagaattccttgaggccttgcctgccgagatccgcgaagaattgctg caacaagaagcggccgatcgacgccggcgagaacgtgagacggcgcgaagacaggcggct gctggtgctggtgctggcgctacagcttccagcactcaaccagcggaagaaatggatgct gtcagcttccttgctactctcgatccctctttgcgccaagctgttctggccgatcagccc gaggatgttcttgcaaccttgggcccagagtacatgaccgaggcccgtggtatgggcggt agcggtcgacgcatggctcagtttggtgacatgagtgcagttgatcaccggcagagaatt gagcctgctgcaggccaggagccgaagaaagagcaaaggcgtcaaattgttcaaatgctc gacaaggctggggttgcaaccctcttacgcctgatgttcatgcctctgcagggcaacgct cgccatcaattgaatgatattcttcacaacgtttgtgagaaccgccagaaccggagtgag gtgatcagtgttctactttcgatcttgcaggatggcagtattgattccactgcgattgaa cgcagcttttctcatctttctctgcgtgcaaaggcaccagggacgcagaagactccgcag tcaaagcgaactctcgctatccagactgcttcgagcgtcagcagtgaagtgactccaatt atggttatccaacaatgtatcgccgcactgtctttcctttcgcagttcaaccctcacatt gcttggttcttcttgacggagcatgactctgcgtcagctggcaaactcaagtccttgcgt aaaggcaaggggaaagaaaaccgagctaacaagttcgctctgaatgcactgctttctctc cttgaccgcaagttgataatggaaagccccaactgtatggagcaactgtccagcctcctt agcagtatcacacagcccttgaccgttcttcttcgtcgtgagaaggagcggcaggaagag agcaagggcaagaagcccgagagacctgaaatcgaagcatctaccgatcaacttgctgaa gctgccgattccagtatggacacatccatgactgatgctctgcttcctactgtggaaatc cctggagcccctggtcaagagaccgtagagagtgaagaggctacctcagccgaagccaag aaatctgaagatttcaaggagcccgctgaggacgagaagcgcaagaagcgaaccatcgag cctcctgtcattccggatcacaacttgcgactggttgtccacatccttgcggctcgtgag tgcaatggcaagacattccgcgatacgctttctaccattaacaatctttccgccattcct ggagctagagacgtgatcggcaacgaattggttgctcaagcccaggcccttagtgatacc atcctgggagatttggaggatcttctccctcatatccaccaggccaagactggtaccgac atgcaaggccttgccctggccaagttctctcccgctagctcagaccaggcgaaattgcta cgtatcctgactgcacttgattatctgtttgatcatgcacgggcggacaagtccagggat ttagagcctggatccgctcccaaggaggatgtgctcaagaaactctatgaaagcgccact ttcggcccgctttggagcaagctgagcgactgcttgactgttattcggcagaaagaaaat atgctgaacgtagctactattcttctccctcttattgaggcactgatggttgtttgcaag aacaccacgctgaaggaccagccgctttctcgtggcagccgtgaattgtcagttaacagc accgccacagctgatgctggtctcagcatggagaacatcttcttcaggtttaccgaagaa catcgcaagattctcaatgagctcgtccgccagaaccctcgcctgatgagcggcacattc tccctgttagtcaagaaccctaaagtcctagaattcgacaacaagcgcaattactttact cggcgtgtccactcccgcggtgccgagcctcgccaccctcatccccctcttcagctttct gtgcgcagagctgaggtcttccttgactctttcaagtccctgtacttcaagagcgcagat gagctgaagtatggcaaactgaatgtacgattccatggcgaggagggtgtcgatgctggt ggtgtcaccagagaatggttccaagttcttgcccgtggcatgttcaaccccaactacgct ttgttcattcctgtcgccgccgatcggactaccttccaccccaatcgcctgagtggcgtc aactcagagcatctcatgttcttcaaattcatcgggcggatcattggtaaggccttgtat gaaggccgtgtcctcgactgccacttcagccgagcagtctataaaaacatcctcggacga tctgtgtctatcaaggacatggaaacgctcgacctggactactacaaatcacttttgtgg atgctcgagaatgacattaccgatattattacggagacattttccattgaaaccgatgac tttggcgagaagcaggtcatcgacctgaagcccggtggtcacgatattcccgttacacaa gaaaacaaggaggagtacgtccagcgcgttgttgaatatcgcctcgtcggatcggttcgt gagcagctggacaacttcctcaagggcttccacgagatcattcctcccgagttgatctcc attttcaacgagcaagagctggaactattgatttctggtcttcctgagattgatgtagac gagtggaagaaccacaccgagtatcacaactactccgcgtcctcctcgcagatccagtgg ttctggcgtgccgtccgctcattcgacaaagaagaacgtgctaagctcttgcagttcgtc actggaaccagtaaagttcctctcaatggcttcaaggaactggagggtatgaatggtgtg agcaaatttaacatccatcgcgactatggccacaaggatcgccttcccagctcgcatacg tgctttaatcagcttgatcttcctgagtatgaaagttacgaagatctccgccagcgtctt tacacagccgtgacggctggcagtgagtactttggttttgaaaggctctttatcatgtcg gccaactccattaagctcttgactggtaacagtcacccagagcttgccaacctagttgct gatcggctcggcattgagttgaccaagatcatggtcttgcaatactccaaccaagaaacc agtgtcacaatcggagagagcgtccgggacgaagatgtcttcattctccaatcgacaaaa cccaatgacatcaacgatggactcatggagctcctgattatgatcaacgcttgcaagact gcctcggcccgccgcatcacagccgtcatccccaacttcccttatgcccgccaagataag aaggacaagagccgtgctcctatcaccgccaagttgatggcgaacatgcttcagaccgcc ggctgcaaccacgttatcactatggacctgcacgccagtcagatccagggcttcttcaat gtccccgtcgataacctgtacgccgagcccagcatgctcaagtatatccgtgagaacctc gatgtcagcaactgcgtcatcgtcagtccagatgctggcggtgccaagcgtgctactgct attgccgatcgtttggacttgcaattcgcgcttattcacaaggaacgtgcccgccccaat gaggtctcacgtatggtccttgtcggtaacgtcaaggataaggtcgctatcatcgttgac gatatggccgatacctgcggcacgctcgccaaggcggccgaaacggtcatgcagcacggt gccaccgaagtcaacgccatcgttgtacacggcattctgtccggcaaggcgatcgagaac ctgaacggcagctgcctcaagcgcattatcgtcagcaacactgtcccattgggcgacaag caagagcagtgcgacaagatccatacgatcgatatcagcccgacattggcagaggcatgc cgtcgtacgcacaacggcgagtcggttagcttcttgttctcgcacaccgtggggtaa

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