Pseudonocardia sp. EC080619-01: AD017_16540
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Entry
AD017_16540 CDS
T04234
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pecq
Pseudonocardia sp. EC080619-01
Pathway
pecq00860
Porphyrin metabolism
pecq01100
Metabolic pathways
pecq01110
Biosynthesis of secondary metabolites
pecq01120
Microbial metabolism in diverse environments
pecq01240
Biosynthesis of cofactors
Module
pecq_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
pecq_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
pecq00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AD017_16540
Enzymes [BR:
pecq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
AD017_16540
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AD017_16540
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ALL82387
UniProt:
A0A0P0SDG0
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Position
3541991..3543532
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AA seq
513 aa
AA seq
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MTGPANTPGRIAFVGSGPGDPALLTVRARDVLAGSPLVITDPDVPESILALAADGAEVRP
AVGQPADIASDLLGEAGQGRSVARLVSGDPLTNDAVVAEAMAVSASGTAFDVVPGVPAST
AVPAYAGVALGSAHVEADVRAGVDWAALAASPGPVVLHATGALLGDVAAGLSAQGVPGET
PVAVTSGGTTSTQRTVSSSVGKLASDGGDLEGPLVLAVGDAAGRRGELSWWESRALYGWR
VLVPRTKDQAGVMSERLRMHGAIPEEVPTIAVEPPRSPAQMERSVKGLVDGRYQWVVFTS
TNAVKAVWEKFHEFGLDARAFSGVKIACVGRSTAEKVREFGIEPELVPDIDEAQSSTSEG
LLDIFPPHDDVLDPVDRVLLPRADIATETLSAGLQERGWEVDDVTAYRTVRAAPPPAPIR
EAIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPATAETAREFGLRVDVQPEES
RVPTLVDALASHTAKLRAEGNLPPPKKVKARRR
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgacaggacctgccaacaccccggggcggatcgccttcgtgggcagcggaccgggtgac
ccggcactgctcaccgtccgcgcccgggacgtgctcgccggctcaccgctggtgatcacc
gacccggacgtgccggagtcgatcctcgccctcgccgccgacggggccgaggtgcggccc
gccgtcggccagcccgccgacatcgcgagcgacctgctcggcgaggccggccagggccgg
tcggtggcccggctggtctccggcgacccgctgaccaacgacgcggtcgtcgccgaggcg
atggccgtctccgcctcgggcacggcgttcgacgtcgtgccgggcgtgcccgcgtccacg
gcggtcccggcctacgccggtgtcgccctgggctcggcgcacgtcgaggccgacgtccgc
gcgggcgtcgactgggcggcgctggccgcgtcgcccgggccggtcgtgctgcacgccacc
ggtgcgctcctcggcgacgtcgcggccgggctctccgcccagggcgtgcccggcgagacc
cccgtcgcggtcacctcgggcggcaccacctccacccagcggaccgtctcgtcgtcggtc
ggcaagctcgcctccgacggcggcgacctcgagggcccgctggtcctggccgtgggcgac
gccgcaggccgccgtggcgagctctcctggtgggagtcccgcgcgctgtacggctggcgg
gtgctggtcccgcggaccaaggaccaggccggcgtgatgagcgagcggctgcgcatgcac
ggtgccattccggaggaggtgccgacgatcgccgtcgagccgccccggtcgcccgcgcag
atggagcgctcggtcaagggcctcgtcgacggccgctaccagtgggtcgtcttcacctcg
accaacgcggtgaaggccgtctgggagaagttccacgagttcggtctcgacgcccgcgcg
ttctccggcgtgaagatcgcctgcgtgggccggtcgaccgcggagaaggtccgcgagttc
ggcatcgagcccgagctggtcccggacatcgacgaggcgcagtcctccacctcggagggc
ctgctggacatcttcccgccgcacgacgacgtcctggacccggtcgaccgcgtcctcctg
ccgcgcgccgacatcgccaccgagacgctgtccgccgggctgcaggagcgcggctgggag
gtcgacgacgtgacggcctaccggaccgtccgcgccgccccgccgcccgcgccgatccgt
gaggcgatcaagaccggcgggttcgacgcggtctgcttcacctcgtcgtcgacggtgcgg
aacctggtcggcatcgccggcaagccgcacgcccgcactctggtcgcctgcatcggcccg
gcgaccgcggagaccgcccgcgagttcggcctgcgggtggacgtgcagcccgaggagtcc
cgggtcccgaccctggtcgacgcgctggcctcgcacaccgcgaagctgcgcgccgagggg
aacctcccgccgccgaagaaggtcaaggctcgccgccgctga
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