Phycodurus eques (leafy seadragon): 133417411 Help Entry 133417411         CDS       T09682                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism pee  Phycodurus eques (leafy seadragon) Pathway pee04020   Calcium signaling pathway pee04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:pee00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     133417411 (ryr3)    04020 Calcium signaling pathway     133417411 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pee04040]     133417411 (ryr3) Ion channels [BR:pee04040]  Voltage-gated cation channels   Ryanodine receptor    133417411 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 Motif Other DBs NCBI-GeneID:  133417411 NCBI-ProteinID:  XP_061561144 LinkDB All DBs Position 18:7252652..7348044 Genome browser AA seq 4949 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTGQSSEGSSDHEKWGGSSRLIKKAGQGGGHRTLLYG HAILLRHSFSGMYLTCLKTSRSLTDKLSFDVGLQVDSIGEACWWTIHPASKQRSEGEKVR IGDDLILVSVSTERYLHLSISNGNIQVDASFMQTLWNVQPTCSSSNMAVGYLVGGHVMRL CRGHDESLTIPGAERSEEEQRIVNYEAGKGVSKARSLWRLEPLRISWSGSHIRWGQAFRL RHLSTGHYLALTEDRGLILQDRERSDTTAASFCFRPSKEKGESGPKRDVDGMGVPEIKYG DSVCFVMHVTTGLWLSYQAPDAKSSRLGPVKRRACLHSEGHMDDGLTLQRCQHEESQAAR NIRNTTFLFTNFIKALDGTTVAVSTEVAGYIEEVLQTLNDLIQYFKQPDSELEHEEKQCL LRSLIKRQDLFKEEGMLTLLSKCIDRMNLYNSAAHFGEMAGEEAGAAWKDILNLLYELLA ALIRGNRNNCTQFSRNLDWLVSKLERLESSSGILEVLHCVLIESPEALNIIQRGHIKSII SLLYKHGRNHKILDILCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVHSMRPN IFLGVAEGSAQYKKWYVEVVIDQVDHFVTGESTHLRVGWANTKGYAPYPGGGEGWGGNGV GDDLYSYSFDGLHLWSGRIPRAVASINQHLLTSDDVVSCCLDLGSPSMSFRINGQPVQGM FEDFNTDGFFFPVISFSAGAKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVK EYKRDHEGVRDLLGTTQFLSQASFIPTPVDTSQIVLPPHMDNIRDKLAENIHELWGMNKI ELGWTYGKVRDDNKRQHPCLVDFTKLPETERSYNLQMSSETLKTLMALGCHVAQVNIHAE DDLKNIKLPKDYMMSSGYKPAPLDLSDVKLTAGQEVLVDKLAENAHNVWAKDRIKQGWTY GIQQDLKSRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYGIDPPDQEAVHVADNQ SIETLRFFRVEQTYAVKTGKWYFEFDARSGGDMRVGWARPGCRPDVELGTDDQAFVFDGY KGRRLHAGSRYFGHPWKKGDVVGCMINMVDKSMIFTLNGELLITNKGSELCFTDFETEDG FIPACSVGMSQTGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVN LPQDHRDIEVTRIDGTVDSPPCLKVTHKTFGTQNSNNEMIYCRLSMPVEYFSADMRLEES FKLSRPPKEDGAMDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFNLNKTRTV TVTLGDERGRVHESVQRSNCYMVCGADAVGPSSSGRSNSDVEIGCLMDLATGLVSFTANG KELSTTYQVEPNTKLFPAVFVRPTSANLFQFEFVKTKDVMPISSAIFKSEHRNPVPQCPP RLDVQTIVAVLWSRMPNTFLSVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILEL SEHEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYN VLISIHLETAKEARLMMNNEFIIPVTDETRSIKLFPDESKKHSLPGVSLSTSLKPRVNFS PACIISTKRQQYLHSPQIPLGILKEKAISMLTEAVQGGGIHIRDPVGGSVEFQFVPILKL IGTLLIMGVLNSEEVRLILLLIDPNVFREGEAAKVDKMAVAAEKEEVNENEKKTMEAGEE ERKESKAVVRGLLEKSLPESVKRQMCELLHYFCDCELKHRIEAIVSFSDNFVSKLQYNQK FRYNELMLALNMSAAVTAKKTKEFRSPPQEQINILLNFTTGDDCPCPEDLQEELNGFHEE LQLHCGIPVEEDEEEQDTSIKGRLLALLYKIKGPPQKAEEEPEEKEQASPTNLKELISQT ITSWAQETHMQDPELVRVMFSLLRRQYDGIGELLRAMKKSYSISAASVQDAINLLASLGQ IRSLLSVRMGMEEERLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMQVMVNVLGGDKSQ EIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAAS SVMDNNGLALALEEPDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFA VFSNGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIEISEDPALDLPKLS AAITTGSGEEEEEIIHMGNSIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLV PTTDLVGVISIPLTKPVVNKDGEVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQL LEVGFLPDLQTAASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFASTEHHTQLIDA TLKTIYRLSKGRSLTKAQRDIIQECLLAICKHLRPSMMQQLLRRLVFDVPMLTEYCNIPL QLLTNHYEQNWKYYCLPSGMNSFGTASEEELLLTKKHFWGIFDSLSQKKYDAELFKMANS CLCAIAGALPPDFVDASLGATLDNHASIDAQGNFDPKSINTANISLPEKLEYIANKYAEH SHDKWSSEKVSAGWKYGESMDEQAKKHPLLKHYKSLSEKEKETYRWPARESLKSMLAMDW NIERTKEGEAMCQQRENEKQKSLETQVNGFTPSPMDLHNFTLSRELQGMVEVIAENYHNI WAKKKKSELMSKGGGSHPLLVPYDILTAKEKYRDRAKAQEIFKFLQISGYAITRGLKDME QDSSSMEKRFAYKFLKRLLQCVDSAQEFIAHLEAIATSGKTDKSPHDQEIKFFAKVLLPL TDQAFKNQCLYFLSTPSKNLSSCGYASNKEKEMVTSLFCKLAALVRHRISLFGSDSSMMV SCLHILTHSLDTRTVMKSGTELVKAGFRTFFDNAAEDLEKLLEMLKLGKFMQSRAQMKSV SQSIHYVTVALLPILTALFDHIRTHEFGVDLLLDDVQLSCYRILTCFYSLGTGKNIFVER YLPVLGESLATLVGAMPVAFLEPHLNTHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPR LDKLLKDVNDVSETGARYSEMPQVIEVILPMLCNYLSYWWGKGPENPPVSGECCTMVISE HLSIILGNILKILNSNLGIDDAPWMKRIAVYSQPIISKAGADLLRTHFLPTLDKLKKKTV KVVSEEELLKADGKSDNQEAELLILDEFAVLCRDLYAFYPMLIRYVDINRSRWLKEPHSD STELFRMVADIFILWCKSHNFKREEQNFVVQNEINNLAFLTGEGETKMSKSGGDQERKHK RRRGEYYSIHTSLIVAALKKMLPIGLNMCTPGDQELISLAKMRYSLKDTDDEVKDHLRQN LHLQDKSDDPAVQWQLNLYKDITMKSGEPVNPEHTVDRVQNISAAVFHLEQVEQPLRNKK CVWQKLLSKQRKRAVVACFRMAPLYNLPRHRAINLFIPAYQRIWIEAEEYSFEEKLVQDL AVSTGQPSPVPRVPCVGTPLPVLPADRLFSSVPVESWERTRAGTSLKASGAPRSRCTKPF KQRSVRGQRLHDRLRRHRASSGAHSSRKPGYTILTAVKTPMKIVEEDEEEVAEVQPDPLH QLILHFSHNALTERSHLEEDPLYIAYADMMAKSCTEDVEEEEEEEKEKTFEEKEMEKQKI LYQQARLHARGAAEMVLQMISASKGHLGPMVTCTLKLGISILNGGNVQVQQKMLDYLKEK RDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSIHTERGSKVLLNDEFTKDL FRFLQLLCEGHNGEFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIID ETGKVNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLS QDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMVDTLMESSNNVEMILKFFDM FLKLKDLTTSENFKEYDLECKGVISKKEFQKSMESQKQYSQSEIDFLLSCAEADESDMFN YKEFVERFHEPAKDIGFNVAVWLTNLSEHMPQDTRLATFLDLAESVLSYFEPYLGRIEIN GSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGGESEKMEMFVNFCEDTIFE MQLASQISEHDAVEQLEAEEEEEVFTILDELAGKEGSSESSSAFASACSSVRKRLRHVRQ IVSVKNIRKKLWKRKKLSIKEMITCFFSFFWMLLAGFFKGISNLIFGFFHVIWSSMFGGG LVEGAKNMKVTDILGNMPDPTQFGIHGDAIEGEKLEALESSGSSDTTVVPAADIAEVDTM LEMLNVPKREGGKLVEHGLGDFSELNGETSTTDHKKAAAKADESPESEPEKADTENKEKE DQPKKEEAKEPATEEKPKAKSSRAKEASPAFMSNVFCTLDVYLTKMLNYLARNFYNLRFL ALFVCFAINFILLFYKVTAEEGGDDDKHWEEDDEDTLFDMDEFVLQESTGYMLPTLRFLA IFHTVISLVCLVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDEDIKGQWDRLVIN TPSFPSNYWDKFIKRKVINKYGDLYGAERIAELLGLDKSALDFDPTVETVEKEASLLSWL SSIDTKYHIWKLGVVLTDNSFLYLIWYTTMSIFGHFNNFFFAAHLLDIAMGFKTLRTILS SVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRRFYNKSEDEDEPDMKCDDMMTCYLFHMY VGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQE QVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQES YVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14850 nt NT seq  +upstreamnt  +downstreamnt atggccgagggcggagaaggggaggacgagatccagttcttgagaactgatgatgaggtg gttcttcagagtgtggccaccattcaaaaggagcatcgcaagttttgcctggccgctgag ggacttgggaaccgcttatgttacctggaaccgacctctgaagctaagtatgttcctccg gacctgtgcatttgtaactttgtactggagcagtcgctgtcagtgcgagcactgcaggag atgctggctaacactggacagagcagcgaggggagtagcgaccatgaaaaatggggaggt tcatcgaggttgattaaaaaggcgggccaggggggcggacatcggaccctgctctatggt cacgccatcctcctgcgccactccttcagtggcatgtacctgacctgtttgaagacgtca aggtctctgacagacaagttgtcatttgatgtcggactacaagttgattcaataggagag gcctgttggtggaccatccaccctgcctccaagcagaggtcagaaggagagaaggtccgc atcggagatgatctgattctcgtcagcgtgtcaacagaacgctacttgcacctctccatc tccaatggcaacatccaggtggatgcgtcgttcatgcaaaccctgtggaacgtccagcca acctgctcctccagcaacatggctgtagggtacttggttggtggtcatgtgatgcgtctc tgtcgtggccatgatgagagtttgaccatccctggagcagaaaggagtgaggaggagcag cggatagtcaactacgaggccggtaagggagtgtcaaaagcccgctccctgtggagactg gagcctctgaggatcagctggagcggaagccacattcgctggggtcaggccttccgacta cgccacctctccaccggccattacctggccctgactgaggaccggggactgatcctacag gacagggagaggtccgacaccactgccgcctccttctgcttcagaccctccaaggaaaag ggggagtcgggcccaaagagagacgttgacggcatgggtgtgccagagatcaaatatggc gattctgtctgcttcgtcatgcatgtgacaactggactgtggctgtcttaccaagcgcct gatgccaaatcgtctcgtcttggacccgtgaaaagaagggcctgcctgcattctgaaggc cacatggatgacggcctgactcttcagcgctgtcagcatgaggagtctcaagctgctcgc aacatccgcaatacaacgttcctcttcaccaacttcatcaaggctttggacggcaccacg gtagctgtgtctacggaggtggccggctacatagaggaggtgctacagacgctgaatgac ctgatccagtacttcaagcagcccgactctgagctggagcacgaggagaagcaatgtctc ctgcgttcgctcatcaaacgtcaggacctgttcaaagaggagggcatgctcaccctcctg tcaaaatgcattgaccggatgaacctgtacaacagcgccgcccactttggtgagatggct ggggaggaggcgggggcagcatggaaggacatcctcaacctcctttatgagctcctggct gcactaattcgtgggaacaggaacaactgcacccagttttctcggaacctcgactggttg gtcagcaaactggaaagacttgagtcatcatcaggcatcctggaagttctgcactgtgtc ttgattgaaagtcccgaggctttgaacatcatccagagaggacacatcaaatccatcatc tctttgctgtacaaacacggacgcaaccacaagattctggacatcttgtgctccctctgc gtatgtaacggtgtggctgtgagagccaatcaaaatttgatctgtgacaacctgcttccc aaaagggacctgcttcttcagacccgactagtcaatgatgttcatagcatgaggcctaac atcttcttgggtgtggccgaaggctctgcccaatacaaaaagtggtacgtcgaggtggtg atcgatcaggtggaccactttgtaacgggtgaatccacccacctgagggtgggctgggct aacacgaaaggctacgccccgtatcctggtggaggcgagggatggggaggcaacggcgtg ggcgacgatctctactcttacagctttgatggtcttcacctctggtcaggtcgcatccca cgggcggtggcctctattaaccagcacctgttgacctcagatgacgtggttagttgttgt ctggacttgggctcccccagcatgtcctttaggatcaacgggcagcctgtgcagggcatg tttgaagacttcaacacggatggattcttctttcctgtcatcagcttctctgctggtgcc aaagtgcgtttcttgttgggtggacggcatggagatttcaagttcctacccccagccggt tactctccgtgctatgaggcgctgctgccaaaggagaagatgcacgtggagcctgtgaag gagtacaagagggatcacgaaggagtccgagacctgttgggaacaacccaatttctttcc caggcctccttcatccccactccggttgacaccagccagattgttcttccgcctcacatg gacaacatccgagacaagctggcagaaaacattcacgaactgtggggtatgaacaagatc gagctaggatggacgtacggcaaggttcgggatgacaacaagaggcagcacccatgcctt gttgattttaccaagttgcctgaaacggaaagaagctacaacctgcaaatgtcaagcgaa acacttaagaccctcatggctcttggatgccatgttgcccaggtcaacattcatgcagag gacgatctgaagaatatcaaacttcccaaagactacatgatgtccagtggatataagcct gcccctctggacctttctgatgtgaagctgactgcaggtcaggaggttctcgttgacaag ctagcagaaaatgcacacaacgtgtgggccaaagacagaatcaaacaaggatggacatat ggaatccagcaggatttaaagagcaggcgtaatcctcgcctggtgccatatgctttactt gatgagcgcacgaagaagtctaacagagacagtctgagggaggccatcaggacaatggtt ggctatggatatggcatcgaccctccagaccaggaggctgtccacgtggcggacaatcag agcattgagactctgcgtttcttccgcgtggagcaaacgtacgccgtgaaaacaggaaag tggtacttcgagttcgatgcccggagtggaggcgatatgagggttggctgggcgagacct ggctgcagacctgatgtggagcttggaacagacgaccaggcctttgtctttgatggatac aagggtcgacgcttacatgcagggagccgctactttgggcatccgtggaaaaaaggagac gtagtgggatgcatgatcaacatggtggacaaatcgatgatttttaccctgaacggcgaa ctcctgatcaccaacaaaggctcagagctttgctttactgactttgaaacagaagacggt tttatcccggcgtgtagcgtgggcatgtctcagacgggacgcatgaaccttgggaaggat gccagcacctttaaatactacaccatgtgtggcctccaggagggcttcgagcccttcgct gtcaacatgaaccgagaggtcaccatgtggtttagcaaacgccttcccacttttgtcaat ctaccccaggatcacagggatattgaggtgacaaggattgacgggacagtggacagccct ccctgccttaaggtcacccacaagacatttggcacccagaacagcaacaatgaaatgatc tactgccgactgagcatgcctgtggaatacttctctgcagacatgcgactcgaggaatca tttaaactcagccgtcctccaaaagaagacggcgctatggactatgggagtatcacaact tactaccattcggtacgagtgtttgccgggcaggaccctgcatctgtgtgggtgggctgg gtcacgccggactatcattactattccaagaacttcaacctcaacaagacgagaacagtc acggtcaccttgggtgatgaaaggggccgggtccatgagagtgtccagagaagtaactgc tacatggtgtgtggagcggacgcagtcggcccttcttcatccggccgctccaactctgac gtggagattggctgtctgatggacttggctaccggcctcgtctccttcactgccaacggc aaggagctgtctaccacttatcaggtggagccaaataccaagctgttccctgctgtgttt gtacggcccaccagtgcaaacctttttcagtttgaatttgtcaagaccaaggatgtcatg ccaatctcttctgctatatttaagagtgagcacaggaacccggtgcctcagtgcccgcca cgactggacgtccagaccattgtggcggtgctgtggagccgcatgccaaacaccttcctc agtgtggagaccgctcgagtcagcgagagacacggctgggtggtccagtgcttggaacca ctgcagatgatggctgtgcatataccagaagaaaataggtgtttggacattttggagtta tcagaacatgaagacttaaggaagttccattatcacacactcaagctgtactgtgccctc tgtgcccttggtaacactcgtgtagcccacgccctctgcagccacttggaccaatcgcag ctcctctatacaatcgacaatcagtatctctctggcatgctgagggaaggcttctataat gttctcatcagcatccatcttgaaacggcgaaagaggctcgcctgatgatgaacaatgag ttcatcatccccgtgacagatgagacgcgctcaatcaagctgttccctgatgagtcgaaa aagcactcgctacctggcgtaagcttgagcacgtccctgaagccaagggtcaacttctcc cctgcttgtatcatcagcaccaagcgtcagcagtatctccacagtccccaaatacccctg ggcatcctaaaagagaaggccatcagcatgcttacagaggccgtgcagggcggcggcatc catataagagacccagtgggcgggagtgtggagttccagtttgtccccatcctcaagctg atcggaacactcttgatcatgggtgtcttaaacagcgaggaggtgagattgattctcctc ctgatcgatcccaatgtgttcagggagggtgaggctgcgaaggtggacaaaatggctgtt gccgcggagaaagaggaggtgaacgagaatgaaaagaagactatggaggcgggagaagag gagaggaaggagagcaaggcggtggtccgtggtcttctggagaagtctttgcccgagtct gtcaaacggcagatgtgcgagctgctgcattacttctgtgactgcgagctgaagcatcgc atcgaggccattgtctccttctccgacaactttgtgtccaagctgcagtacaaccagaag ttccgctacaatgagctcatgctggcgctcaacatgtccgccgccgtcacggccaagaag accaaagagttccgctcacctcctcaagagcagatcaacatcctattgaacttcaccacg ggcgatgactgcccatgccctgaggacctccaggaagaactcaatggcttccatgaagaa ctgcagctgcactgcggaatcccagtggaggaggacgaggaagagcaggacacatcgatt aaaggtcgtctcttggccttgctctacaagatcaagggtccgcctcaaaaggctgaggaa gaacctgaagagaaagagcaggcttcccccaccaatctaaaggagctgatctcccagact ataaccagctgggcccaggagacccacatgcaagatcccgagctggtccgagtgatgttc agtctgctaaggaggcagtatgatggcatcggggagctgcttcgtgccatgaagaaatcc tactccatcagtgctgcatccgtgcaagacgctattaacctgctggcctccttgggtcag atcaggtctctgctgtccgtgcgtatgggcatggaggaggaaaggcttatgattgatgga ctgggggacataatgaacaataaggttttctaccagcatccaaacctcatgagagtgttg ggcatgcatgagaccgtaatgcaggttatggtcaacgtgcttggaggagacaagtcacag gaaattgccttccccaagatggttgcaagctgttgtcgctttttgtgctacttctgtcgt attagtcgccagaaccagaaagccatgtttgaccacctaagctatctgctggagaacagc agtgtcggtctggcctctgaagcaatgcggggatctactccgctggatgttgccgcatca tcagtgatggacaataatggcctcgctctggccctggaggaaccagatctagaaaaggtg gtgacatacctcgcaggatgtggtcttcagagttgtgccatgctggttgccaagggttac ccagacctgggatggaaccccatagaaggggagcgttacctgtcattcctgaggtttgcg gtcttctccaacggtgagagtgttgaggaaaatgccaacgtggtggtgaagctgctgatc cgacgtcccgagtgtttcggccccgctctgaggggagaggggggtcagggtctgctggct gccatgaaagaggccatcgagatctccgaggatcctgctctggacctgccgaaactttct gctgccatcacgactgggtcgggtgaagaagaggaagaaataattcacatggggaactct atcatgtctttctactcggccctcattgacctgctaggtcgctgtgccccagagatgcat ctcatcaacgcaggtaaaggtgaagcgctgcgtattcgagccattctacgctccctggtt ccaaccacagacctggttggcgtcatcagcatccccctcacaaagcctgtagttaacaaa gatggcgaagtgacagaacccgatatgtcagcctgtttctgtccggatcacaaggccccc atggtgctcttcctggacagagtgtacggcatcgaggaccagagcttcctcctccagctg ttggaggtcggcttcctgcccgacctccaaactgctgcctctttagacacggaagtgcta agtaccacggagacggcgttggccatgaacaggtacatcggctcagctctgctgcctctg ctgacccgctgcgccgccttgttcgccagcaccgagcaccacacgcagctgatcgacgcc acgctaaaaaccatctatcgcctctccaaaggacgctcgctcaccaaagcgcaaagagat attattcaggagtgccttctggctatttgcaagcatctgcgtccctccatgatgcagcag ctgctccgacgcttagtgtttgatgttcccatgctcacggaatactgcaacatacctcta cagttactgaccaaccactatgaacagaactggaagtactattgtcttccatctgggatg aacagctttggcacagcctcggaggaggagctccttctcaccaagaaacacttctgggga atttttgactcactttctcagaagaaatatgatgctgaactgttcaaaatggccaactcc tgcctttgcgccattgctggagccctgcctcctgactttgtggatgccagtttaggagca acactggataaccatgcatctattgatgcacagggaaactttgaccccaaatctataaac acagccaatatctccctacctgaaaaacttgagtacattgccaacaaatatgcagagcat tcccatgacaagtggtcttcagagaaggtatcagcagggtggaaatacggagaaagtatg gatgagcaagccaaaaagcatccactgcttaagcattacaaatctctgagcgagaaggag aaagaaacataccgatggccggcgagggagtcgttgaagagcatgctggcgatggactgg aacattgagaggaccaaggagggagaggccatgtgccaacaacgcgagaatgagaaacaa aagagtttggagacacaggtcaatggattcactccttctccaatggacctgcacaatttc acattgtctagagaactgcagggcatggttgaggtgattgctgaaaattatcacaacatc tgggccaagaagaagaaaagtgaactcatgagcaaaggaggagggagccacccgctgctg gtaccctatgatatcctgactgctaaagagaaatacagagacagagcgaaggcccaggag atcttcaagttcctgcagataagcggctatgcaatcacaagaggtttgaaagacatggag caggactcttcatccatggagaagcgatttgcatacaagtttctcaaaaggctgctgcaa tgtgtcgactctgcccaggagtttatcgcacaccttgaggcaattgccacgagcgggaag actgacaaatcacctcatgaccaggaaatcaagttctttgcaaaggtgttgctcccgctg acagatcaggcttttaagaaccaatgcctctacttcctgtccacgcccagcaagaacctg agcagctgtggctatgcctccaacaaggagaaagagatggtcacaagccttttctgtaaa ctggcagctcttgtcagacacaggatttctctctttggaagtgactcttcaatgatggtg agctgccttcacattctcactcactcacttgacaccagaacagtaatgaagtcaggtacg gagctggtaaaagccgggtttcggaccttctttgataatgcagcggaggacctggagaag cttctagagatgctcaaactggggaagttcatgcagtcgcgtgcccagatgaagagcgtc agtcagagcattcactacgtgaccgtggcgcttctgcccatcctcactgccttatttgat cacattagaacgcatgagtttggagtggacctgctgttggatgacgttcagctgtcctgc taccgaatcctgacttgtttctactctcttggaactggaaagaacatcttcgtggaaagg tatctgccagtactcggtgagagcctggccactctagtgggcgccatgcctgtagctttc ctggaacctcacctgaacacccacaacccgctgtccgtcttcaacaccaagacaccacgc gagagggccattctcagtatgcctgatacggtggaggaaatgtgtccagagatgcctcgt cttgacaagctgctgaaggatgtcaacgatgtctcagagactggtgcacgctacagtgag atgccgcaggtgattgaagtgatcttgcccatgttgtgcaactacctgtcctactggtgg gggaaaggtccagaaaaccctcctgtgagtggtgagtgctgcaccatggtgatatcagag cacctcagcatcattctcgggaacattctcaagatcctcaacagcaacctgggcattgat gatgccccctggatgaagaggattgcagtctactctcagccaattatcagtaaagcagga gccgatctgctgagaacccattttttgccaacgctggacaaactgaaaaagaagacagtg aaggtggtgtctgaagaggagttattgaaggctgatggcaaaagtgacaatcaggaggca gagcttcttatcttagatgagtttgctgtgctctgccgagacctctatgccttctacccc atgctcattcgctatgtagacatcaacaggtcgaggtggcttaaggagcctcattcagac tccacagaactcttcaggatggtggcagatatcttcatcctctggtgcaagtctcataat tttaagcgtgaggagcaaaactttgtcgtgcagaacgagatcaataatttggccttcctc actggagaaggcgagacaaaaatgtccaagtctggtggcgaccaggagagaaagcacaag cgtcgtcgaggggagtactactccatccacacctctttgattgtggctgcactgaaaaag atgctgcccatcggcctcaacatgtgcaccccaggagaccaggagctcatctccttggct aagatgcgctacagtttgaaagatactgatgatgaggtgaaggaccacttgcgccagaac cttcatctgcaggacaagtctgatgaccccgcagtccagtggcagttgaacctctacaaa gacatcacgatgaagagtggtgagccagttaacccagaacacacagtggatcgggttcag aacatctcggctgcagttttccatctggaacaggtggagcagcctttaaggaataagaaa tgtgtgtggcagaagctgctgtccaaacaacgcaaacgggctgtggtggcctgcttccgt atggcccccctttacaatcttcctaggcatcgtgctatcaacctcttcatcccagcctat cagagaatatggatagaggcagaggagtactcctttgaggaaaagctagttcaggatctg gcagtaagtactgggcagccctcgcccgtgccccgtgtgccctgcgttggcacccctctg ccagtcctgcctgccgatcgcctctttagctctgtgcccgttgagtcttgggagcgcaca cgggcggggacttcgctcaaagcatcgggggcaccccgttctaggtgtacgaaacccttc aaacagagatccgttcgaggtcaaagactgcatgatcgactcaggaggcacagggccagc tctggcgctcacagctctagaaaaccaggctataccattctgacagcagtgaaaaccccc atgaagatagtggaggaggatgaagaagaggtggctgaagtccagccagaccctctacac caactcatcctccattttagccacaatgctctgaccgaaagaagtcacttggaagaagat cctttgtatatcgcgtatgctgacatgatggcaaagagctgtacagaggatgtggaagaa gaggaggaagaagagaaagagaagacatttgaggaaaaggagatggaaaagcagaagatc ttgtatcagcaggctaggctgcatgctcgtggtgcggctgagatggtgttgcagatgatt agtgctagtaaaggacacctaggccccatggtgacttgcaccctcaaacttggcatttcc atcttaaatggcggcaatgtgcaagttcagcaaaaaatgctggattacttgaaagagaaa agggatgcaggctttttcaaaagcctctcaggactgatgcagtcatgcagtgtcttggac ttgaatgcattcgagaggcagaataaggcagaaggactcggcatggtgacagaagaaggt tcaatccacaccgagcggggttctaaggtgttactgaatgatgagtttacaaaagatttg ttccggtttttgcaacttctgtgcgagggacacaatggggagttccagaacttcctgaga acacaaactggaaacacaaccacggtcaacattattatcagcactgttgactacttgctc cgccttcaggaatcgatcagtgacttttactggtactactctggcaaagatatcattgat gagactggaaaagttaacttctccaaagcgttgtctgtggccaagcagatattcaactca ctgactgaatatatccagggcccttgtattggaaaccagcagagtctcgctcacagcaga ctgtgggatgcagttgtgggcttcttgcatgtttttgccaacatgcagatgaaactgtct caggatgccagtcagattgaactgctgaaggagctgatggatttgcagaaggatatggtt gtcatgctgctgtctctgctagaaggcaacgttgtgaatggaacgatcgggaagcagatg gttgacaccctcatggagtcttctaacaacgttgagatgatcctgaaattcttcgacatg ttcctcaagctgaaggacctgacaacgtcagaaaatttcaaggagtatgacctcgagtgc aagggtgtcatttcaaagaaagagttccagaaatcgatggagagccaaaagcagtacagc caatcggagatcgacttcctcctctcttgtgcggaggccgacgaaagtgatatgttcaac tacaaggagtttgtagagcgattccatgaacccgccaaagacatcggcttcaacgtggcc gtatggctgacgaatctgtccgagcacatgccacaggacacccggcttgccaccttcttg gatctggccgagagcgtgctgagctacttcgagccttacctcgggcgtatcgaaatcaac ggcagtgcaaaacgcatcgagagggtgtactttgagatcagcgagtccagccgagagcag tgggagaagccgcaagtcaaggagtccaaacggcagttcatcttcgacgtagtcaatgag ggcggcgagagcgagaagatggagatgtttgtcaatttctgtgaggacaccatttttgag atgcagttggcctcgcagatctctgaacatgatgctgtggagcaactggaggcggaggaa gaggaggaggtattcaccatcctagatgaactggctggcaaagagggctcttcagagtct tcctctgctttcgcttctgcatgcagctcagtcaggaagaggttgcgtcacgtacgccaa attgtttctgttaaaaacatccgcaagaagctctggaaacggaagaagctgagcataaaa gagatgatcacatgcttcttctctttcttctggatgctgttagctggcttctttaaagga atcagtaacctcatatttggtttcttccacgtcatctggtcttccatgtttggcggcggc ttggttgaaggtgccaagaacatgaaggtgacagatatcctcggaaatatgcctgatcca actcagtttggcatccacggagatgccattgaaggagagaaattagaggccttggagtct tcgggaagttctgacacgactgtggttccagcggcggacatagctgaggttgacactatg ttggagatgctgaacgtgcccaagagggaaggcggaaagcttgtggagcatggcttgggg gatttttctgaactcaacggtgagacttccaccacggaccataagaaagctgctgccaag gctgatgaatcccctgagagtgaacctgagaaagcagacacggagaacaaggagaaggag gaccaaccaaagaaagaggaagccaaggagccagcaaccgaggaaaagcccaaagccaaa tcaagtcgagccaaggaagcttctccggccttcatgtcaaatgttttttgcacgcttgat gtctatctgaccaaaatgctgaattatctggctcgcaacttctacaatctgcgtttcctg gctctgtttgtgtgttttgccatcaacttcattctgctcttctacaaggtcactgcagag gaagggggagatgatgataaacactgggaggaggatgacgaggacacgctctttgacatg gatgagtttgttctccaagagagtaccggctacatgttgccaacgctgcgcttcctggcc atattccacaccgtcatctcgctggtgtgtttggtgggatactactgtctgaaggttcct ttagtggtgttcaagcgagagaaggagatagccaggaagctggaattcgatgggctttac atcaccgagcaaccgtctgatgaggacatcaagggtcagtgggatcgacttgtcatcaac accccttcctttcccagcaactactgggacaagtttatcaagcgtaaggtgatcaacaaa tacggggacttatacggagccgaacgcatcgccgagctcttaggcctggataaaagtgct ctggactttgaccccacagtggagacggtagagaaggaagcttcactgctttcctggctc agctccattgatacaaaataccacatttggaaattgggagtggttttgaccgacaattcc ttcctgtatctaatctggtacaccaccatgtccatttttgggcacttcaacaacttcttc tttgctgctcacctgctggacattgccatgggcttcaagaccctccgcaccatcctgtca tctgtgacacacaatggcaagcagttggtgctgaccgttggtctgctggcggtggtcgtg tacctctacactgtggtggccttcaactttttccgaaggttctataataagagcgaggac gaagacgagcctgacatgaagtgtgacgacatgatgacgtgctatctgttccacatgtac gtgggcgtaagagccgggggtggcatcggagatgagttggaggacccggctggagacccc tatgagctctaccgcatcctttttgacatcaccttcttcttcttcgtcattgtcatcttg ctggccatcattcagggtttgatcattgatgcctttggtgagctgagagaccagcaggag caagtgaaggaggacatggagaccaaatgcttcatctgtggcatcgggaacgactacttc gatcggacacctcacggttttgaaactcacaccttacaggagcacaaccttgcaaactac ctgttcttcctgatgtacctgattaacaaggatgagacggaacacacaggccaggagtcg tatgtgtggaagatgtaccaggagagatgctgggacttcttcccgaccggcgactgtttc cggaagcaatacgaggatcagttgggctaa

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