Phycodurus eques (leafy seadragon): 133417542 Help Entry 133417542         CDS       T09682                                  Symbol ryr2a Name (RefSeq) ryanodine receptor 2 isoform X1   KO K04962   ryanodine receptor 2 Organism pee  Phycodurus eques (leafy seadragon) Pathway pee04020   Calcium signaling pathway pee04260   Cardiac muscle contraction pee04261   Adrenergic signaling in cardiomyocytes pee04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:pee00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     133417542 (ryr2a)    04020 Calcium signaling pathway     133417542 (ryr2a)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     133417542 (ryr2a)    04261 Adrenergic signaling in cardiomyocytes     133417542 (ryr2a)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pee04040]     133417542 (ryr2a)    04990 Domain-containing proteins not elsewhere classified [BR:pee04990]     133417542 (ryr2a) Ion channels [BR:pee04040]  Voltage-gated cation channels   Ryanodine receptor    133417542 (ryr2a) Domain-containing proteins not elsewhere classified [BR:pee04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    133417542 (ryr2a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 baeRF_family6 Motif Other DBs NCBI-GeneID:  133417542 NCBI-ProteinID:  XP_061561260 LinkDB All DBs Position 19:complement(17089382..17444392) Genome browser AA seq 4962 aa AA seqDB search MADGEGEDEIQFLRTNDEVVLQCSATIHKEQQKLCLAAEGFGNRLCFLESISNSKNVPPD LSICTFVVEQSLSVRALQEMLASTEAKTGGTIQGGGHRTLLYGHAVLLRHSYSGMYLCCL STSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSISSERYLH LSYGNCYQNVDAAFQQTLWSVTPICSGSEVAEGFLIGGDVLRLLHGHMDECLTVPSGDYG DEQKRTVHYEGGAVSSHARSLWRLETLRVLWSGSHIRWGQPFRLRHVTSGKYLSLTKAKS LRLMDKEKADVKSTAFCFRSSKEKVDLGLKKEVDGMGTPDIKYGDSLCYIQHVDTCLWLT YQTADAKSARIGDVQRKAFMHHEGHMDDGLTLSRSQHEESHTARVIRSTVFLFNLFIRSL DTLRAKGTSTTFDIPIDSISLSLQDLIGYFQPPGEHLEHEDKQNRLRALKNRQNLFQEEG MIALVLECIDRLHVYSSAAHFTEAAGREAGEAGEAWSSSLNSLYQLLAALIRGNRKNCAQ FSGSLDWLIGRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKV LDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLINYVSSMCPNIFLGVSEGSAQS KKWYYELIVDQALPFVTAEASHLRVGWANNNGYMPCPSSGESWGGNGVGDDLYSFGFDGL HLWSGCIGKTVSSPNQHLLRADDVVSCCLDLSVPSISFRINGQPVQGMFENFNSDGLFFP VASFSAGIKLRFLLGGRHGEFKFLPPPGYAPCFEAVLPREKLKLGPSQHQPAAGDLLGPT VTMSQAAFTPMPVNTSQIVLPFHLERIKDKLAENIHELWVMNKIEFGWTYGVIRDDTKRQ HPCLVEFSKLAEQERSYNLQMSVETLKTLLALGCHVGLSDEHAMEKVKSVKLSSNYELSS GYKPAPLDLYHIKLTSTQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVP YSLLDERTKKSNKDSLREAVRTLLGYGYNLEAPDQDHTHFDHSNMSAERFRIFRAERSYC VNSAKWYFELEVVTAGEIRVGWARPGCLPDLELGSDEKAFVFDGFKVQRWHQGNEHFGRA WQTGDVVGCMVDLNEHTMMFTLNGEVLLDDSGSELAFKDFDVGEGFIPVCSLGVCQAGRI NFGKHVSTLKYFTICGLQEGYEPFAVNMNRDVTIWLSKRLPQFVPVPHDHQHIEVTRIDG TVDSCPCLKVTQKSFSSQNSNGDITFYRLSMPIECAESFSRPPSNGSLLSLKTELEDFES DFEVLMKTAHGHNGPNGPDRGEFNNHKDCNQEKTSKLKQRFLLKKNKPDNSNPSPACLSE EVMVDDRNEYEILMKTSIYSYSVRIFPGQEPSNVWVGWVTSDFHHHEPGFGLDKVQIVTV TLGDEKGKVHESIKRRNCYMVWAGESSSPEGRSNKGLEIGCLVDTANGLLSFTANGKELS TYYQVEPSTKLFPAVFAKATSLNVFQFELGQIKNVMPLSAGLFMSERKNSVPQCPPRLHV QFLTPVVWSRVPNHYPKVSVSRVNDRHGWLVHCNEPLQFLSLHIPEENRSLDVLELSERR DLLKFHYHTLRLYSAICALGNNRVAHALCSHVDEAQLLHAIENKYMPGLLRAGYYDLLIE IHLSNYATARLMMNNEYIVPMTDETKSITLFPNEEKKHGVPGIGLSTSLRPRMHFSSPSF VCGSESSSRTDFNNGSRSVDSCQYSPEFPLDILKTKTVEMLTEAVCEGNMHARDPIGGST ELLFVPLIKLFYTMLIMGVFQNGDLKNILRLIEPSMFSERCELQEEMQRNVEMETEEGGE EEGRNIPKQGLLQMKLPEPVKVQMCHVLQYLCDCQVRHRIEAVVAFSDDFVACLQENQRF RYNEVMLALNMSAALTAKKTKEFRSPPQEQINMLLSFKKEMQECPCPEYIREQLLDFHED LMKHCGIELTEDGALDGDSNFTIRDRLMSLVEKVTDLKNKMVNLPKEKTDRKPSTLQQLI SETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGQVWALPKTYTINSVSIEDTINLLAA LGQIRLLLSVRMGREEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLSGG DSKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDV AAASVMDNNELALALREPDLEKVVQYLAGCGLQSCTMLVYKGYPDIGWNPVEGERYLDFL RFAVFCNGESVEENANVVVKLLIRRPECFGPALRGEGGDGLLATMEDAIKISLDPLRDGP SSASERSNIPNDGLDEEDDTIHLGNAIMTFYAALIDLLGRCGPEMHLIHAGKGEAIRIRA ILRSLIPIEDLVGVICIPFSMPSLEKDWVVLEPDMSAGFCPDHKAAMVLFLDRVYGVQDR NFLLHLLEVGFLPDLRAAASLDTVALSATDMALALNRYLCTAVLPLLTKCAPLFAGTEPF ASLIDSLLHTVYRLSKGCCLTKAQRDSIEECLLAVCGKLRPSMMQHLLSRLVFDIPLLNE HTKMPLKLLTNHFECCWKYYCLAGGWGSFGAASDEELHLCRKLFWGIFDALSHKPYDQEL FKVALSCLSAVGGALPPDYMESNYMAMMDKQSSMDTEGNFTPQPADTANVTVPDKLDIFI ARYAEHNHEKWCFEKFSSGWSYGEKACEISRTHNLLKPFKALTDKDKELYYWPIRESLKT MLSWGWSINRIRETDSATLHNTSRRISQASQPSFEGAQCFNPRPIDMSNVTLSRDSQSMA ELLAENYHNIWARIKKIDLEAKGGGNDPLLVPFDTLTAKEKLKDRQKALDILKFLQINGY TLSRGVKSQELDTPAIEKRFAYTFLEQLINYVDQAHDHMLEFDMGTRQRGVKSPHEQQMK FFLKVVLPLVDQYFRNHRLYFLSTSIHSISNGGHASNKEKEMVTSLFCKLGVLVRNRISL FGNNATSIVNCLQILGQSLDARTVMKTGLESVKAALQSYFDNAAETLGKTQENLKLGQFT HSKEQPRGVPQIINYTTFGLLPILSSLFEHVGKNNFGEDLILDEIQVSCYRILNSLYFLG TNESIYVERHRPALGKCLAAFSTAFPVAFLEPHINKFNNFSLYNSKSAEDRNALGLPSQV VEVCPMIPNLERSLEEIIEVAESGMKYTQMPHVMEVVLPVLCSYMSHWWEHGPENNPNQA DSCCTSVTSEHMNILLGNILKIIYNNLGIDEGAWMKRLAVFSQPIISKAKSQLLKTHFLP LMKKLRKKAAVVLADEEQGKAEGRGEISETELLIMDQFSVLVRDLYAFYPLLIRFVDYNR ATWLKESNPEAEVLFQMVAEVFIFWAKSHNFKREEQNFVVQNEINNMSFLISDSKCKMSK GIGSFQERKKLRRKGDQYSLQTSLIVATLKRLLPVGLNICVPGEKELIALAKNRFSQKDT EDEVRQVIRNNLHLQGKLQDPAIRWQRALYRDILNNCDDTPDPEKNVERVLDIAHVLFHL DQVEHPQHSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIEAEE HFFEDKLIEDLAKSGEQQAFEEMEGVKHIDPLHQLIQLFSRTALIEKCKLDEDHLYMAYA DIMAKSCHDEEDEDGEEVKSFEEKEMEKQKLLYQQERLHDRGAAEMVLQTISASKGEMGS MVASTLKLGIAILNGGNSTVQLKMLDYLKNRKDVGFFQSLAGLMESCSVLDLNAFERQNK AEGLGMITEEGSVNSVLVFGEKVMQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNT TVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAINVAKQVFNTLTEYIQG PCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMM EGNVVNGTIGKQMVDMLVESSNNVEMILKFLDMFLKLKDVTSSDAFKEYDPDGKGVISKR DFQKAMENHKHYTQSEADFLLSCAETDENELLDYEEFVERFHEPAKDIGFNVAVLLTNLS EHMPHDNRLHTFLELAESVLNYFQPYLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVK ESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQMSDTGERSAVKEDSEQERPDM DNPETSFFSVTTARMALTALRYSFMILIKVLSIKSLKKQMKKLKSMTSKDMVTALVSFYW SALQGLFHMAFSVVRGFCRIFYNNIFGGNLVDGAKRIKVSELLANMPEPTQDGVRLKGKD KERKSSNRSSMKEDLAYLAVNTSDTELLSDIFGLDLRREGGQYKISPHNPNASLTEILNS PLPPPPPCAASAAPPPELRQMDQSKSPSLEEKKEETTENACETKKRGEHEEKQEKNVKMK SKVKRHKMSKDEPDLQESAVSKKIVAYQRKLLNYFARNFYNMRMLALLVAFAINFILLFY KVSKSSSVAEEVITNSPPDSTIQWDPLSGEPMVEKKDGVMDDLGEPLKLAMVHFVLEEGS GYMEPTLRILAILHTVISFFCIIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDD IKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGHYRINELLGLDKAALDFSGAHKK RKPRKDTYLAAVLNSIDVKYQIWKLGVVFTDNSFLYLAWYMTMSILGHYNNFFFAAHLLD IAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGELPDMK CDDMLTCYMFHMYVGVRAGGGIGDQIEDPAGDEYEMYRIIFDITFFFFVIVILLAIIQGL IIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLSNYLFFVMYL INKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN NT seq 14889 nt NT seq  +upstreamnt  +downstreamnt atggctgacggggaaggcgaggatgaaattcagtttctgcgaacaaatgatgaggtggtc ctacagtgttcggccacaatccataaggagcaacagaaactctgcctggctgctgaaggc ttcggaaacaggctgtgtttccttgaatcaatctccaattccaagaatgtacctccagat ctgtcaatatgtactttcgtggttgagcagtcactgtcggttcgtgcccttcaggagatg cttgccagtactgaagcgaagaccgggggaacgatccaagggggtggtcatcgcacgtta ttatatgggcatgcggtccttctgcgtcactcttacagtggaatgtacctgtgttgtcta tccacctcccgatcatccacagacaaattagcttttgatgtggggcttcaggaagacacc acaggtgaagcgtgctggtggaccattcatccagcatcaaagcaacgttccgagggggag aaggttagggtgggggatgatctcattctggtcagcatttcatccgagagatatctgcat ctatcctatggcaactgttatcaaaatgtagatgcagccttccagcagactctgtggagc gttactccaatctgttctggcagtgaagtggcagaaggtttcttgataggcggggatgtc ttgcgcctccttcatggtcacatggatgagtgtttaactgttccatctggagactacggg gatgagcagaagagaacggtgcattatgagggtggagcagtgtccagtcatgccaggtcc ctgtggagattagagacactgcgagttctgtggagtggtagtcatattcgctggggccag ccgttcagactgaggcacgtgacaagtgggaagtatctgagtctgacaaaagcgaaatca ttacgactaatggacaaagaaaaagcggatgtcaagtcaacagccttttgtttcagatct tccaaggaaaaggttgaccttggtctaaaaaaggaagtggatggaatgggtacccctgac attaagtatggtgactcattgtgttacattcaacatgttgacacatgtctgtggcttacc taccagaccgctgatgcaaaatctgcacgcatcggtgacgttcaaagaaaggccttcatg caccatgaaggtcacatggacgacgggctgacgttgtcaaggtcacaacatgaagagagt cacactgccagagtcatccgcagtactgtgttcttgttcaacctgttcatcaggagtcta gatacgttaagagcaaaaggaacgagcacaacatttgatataccaatcgactcaataagt ctgagtcttcaggatctgattggctacttccagccgcccggcgagcacctagaacatgaa gacaagcagaatcgcttgagagctttgaagaataggcagaacctcttccaagaagaggga atgatcgcgctggtcctggagtgtattgatcgactccatgtgtacagcagtgcagcccat ttcacagaagcagctgggagggaggcaggagaggcaggagaggcctggagctccagcctt aactctctctaccaactactggctgcactgatcaggggcaacaggaagaactgtgctcag ttttcgggttccttagactggctcatcggcagattggagagactggaggcctcctctggt atactggaggtgcttcactgtgtgctggtggagagtcctgaagcactgaacattatcaaa gagggacatatcaaatccataatttctcttctggataaacatggacgtaaccacaaggtt cttgatgtgttatgttcgctttgtgtgtgtcacggtgtggcagtccgctcaaaccagcac ctgatctgtgacaacctactgccgggaagagatttgttgcttcagacacgcctgatcaat tacgtaagcagcatgtgccctaatatctttctgggtgtcagtgaaggctctgcacagtct aagaagtggtactatgagctgattgtagaccaagcactgccattcgtcactgctgaggca tctcacctcagggtgggctgggccaacaacaacggctacatgccctgccccagcagtggg gagagttggggcggcaatggagtgggtgatgacctctactcctttggctttgatggactc catctttggtcaggctgtattgggaagactgtcagctcacccaaccagcaccttctgaga gcagatgatgttgtgagctgctgcttggaccttagtgtgcccagtatctccttccggatc aacggccaaccggttcagggcatgtttgagaacttcaactctgatggcctctttttccct gtggccagcttctctgctggaataaagcttcgtttcctccttgggggtcgccatggagag tttaagtttctccctcctccaggttatgctccgtgctttgaggccgtgctgcccagagag aaactaaaacttgggcccagtcaacaccagcctgcagccggggaccttttgggacccact gtcaccatgagccaggcagcattcacacccatgcctgtaaacaccagccagattgttttg ccatttcacttagagaggataaaggataagcttgcagaaaacatccatgagctgtgggtg atgaacaagattgaatttggctggacctacggtgtaattcgagatgacaccaagaggcag cacccatgtctggtggagttctccaagttggcggaacaggaacgaagttacaacttacag atgtctgtggaaactctcaaaactctccttgctttggggtgccatgtcggtctttcagat gaacatgctatggagaaagtcaaaagtgtaaaactgtcatcaaactatgagttgtccagt ggttacaaacctgctcccctggacctttatcatatcaaactgacctccactcaggaagcc atggtggacaaattggctgaaaatgcacacaatgtctgggcaagagaccgcatccgccag ggttggacctatggaattcaacaggatgtgaagaatcgcagaaatcctcgtctggtgccc tacagtcttttggatgagagaaccaagaagtcaaacaaagatagtctaagagaagctgtc agaactctgctgggttatgggtacaacctggaagctcctgaccaggaccacactcatttt gatcacagcaatatgtctgctgaaaggttccggatcttcagagctgaaagatcctactgt gtgaattcagcaaagtggtactttgagctagaggtagtgacagcaggagagattagggtt ggctgggcaagaccaggatgtctaccagatctagaattgggttctgatgaaaaggccttt gtctttgatggattcaaggttcagcgctggcaccagggaaacgagcactttgggcgtgcc tggcagacaggtgatgtcgttggctgcatggtggacctgaatgaacacaccatgatgttc accctgaacggagaagtgctgcttgatgactctggctctgaactggctttcaaagacttt gatgttggtgaaggtttcatccctgtgtgcagtttgggtgtgtgccaggctgggaggatt aactttggtaaacatgtcagtaccctgaaatacttcacaatatgcggtctgcaggaaggc tacgaaccctttgctgtcaacatgaatcgcgatgtcacaatatggctcagtaaaagactg cctcagtttgtacctgtacctcatgaccaccaacatatagaggtgacaagaatagatggg acagtggattcatgtccttgtctgaaggtcacacaaaagtcatttagttcacagaacagc aacggcgacattactttctacagactgagcatgcccattgaatgtgctgaatccttctct aggcctccgtcaaatggcagtctcttgtcacttaagacagagctagaagactttgaatcc gactttgaggtcctaatgaaaacagctcatggccacaatggtccaaacggtccagacaga ggtgaattcaacaatcacaaagattgcaaccaagagaaaacctccaagctcaaacaaagg ttcttgttgaagaagaataaaccagacaactccaatccctcccctgcctgtctatcagaa gaagtgatggttgatgacaggaatgaatatgaaatactcatgaaaacatcaatttactca tattccgtaaggatcttccctggccaggagcccagcaatgtgtgggtgggctgggtcacc tctgactttcatcaccatgaaccaggctttgggttggacaaggtccaaattgtaacagtg actttgggagatgaaaaaggcaaagttcatgagagtataaagcgccgtaactgctatatg gtgtgggctggagagagcagcagtccagaaggaaggagtaacaaaggtttagagattgga tgtttggttgacacagcaaacggactgctgtcctttacagctaatggcaaagaactcagc acatactaccaggtggagcccagtactaaactcttcccagctgtatttgccaaggctacc agcctgaatgtcttccagtttgaactgggacaaattaagaatgtgatgcctctgtcagct ggtttatttatgagtgagaggaagaattcagtcccacaatgtcctccccggctgcatgtc cagtttctcactcctgtagtatggagtcgtgttcccaatcactatcccaaggtttcagta tcacgagtcaatgaccgacatggctggctggttcattgtaatgaaccattgcagtttttg tctctgcacatacccgaagagaacaggtcattggatgtcctggagctatctgagaggaga gacttattaaagtttcactatcataccctcagattgtattctgcaatctgtgctcttgga aacaaccgggttgctcacgccctttgctcccacgtggatgaggcacagcttctgcatgct atagagaataaatatatgccaggtttgctacgtgcaggctactatgaccttttgattgag atccatctgagcaactacgcaaccgctcgtctcatgatgaacaatgagtacatcgttcct atgactgatgaaaccaagagtataaccctgtttcccaatgaggaaaaaaaacacggtgtg cctggcattgggctcagcacttccctgagaccaagaatgcacttttcctccccaagtttt gtctgcggttctgagtcatcatcacgtaccgatttcaacaatggctcacgatcagtggat tcttgccagtacagccctgaattccccttggacatactaaaaacaaaaacagtcgagatg ctgacagaggcagtatgtgagggcaacatgcatgcaagagatcccattgggggcagcact gaacttctctttgtgccgctcataaagctcttttacaccatgctcatcatgggtgttttc caaaatggagatctgaagaacatactgcgactgattgagccatctatgttctcagaaaga tgtgaattgcaggaggaaatgcaaaggaatgtggaaatggagacagaggaaggaggagag gaggaaggaagaaacataccaaagcagggattattgcagatgaaattaccagagcctgta aaagttcagatgtgccatgttcttcagtacctgtgtgactgccaggtgcgtcatcggatt gaagcagtagtcgccttctctgatgatttcgtagcttgtctccaagaaaaccagcggttt cgctacaatgaagtgatgctcgcgctgaacatgtctgctgctctcacagccaagaagacc aaagaattccgatctccacctcaagaacagatcaacatgctgctgagctttaagaaggag atgcaggagtgcccctgtcccgaatatatccgagagcagctgcttgacttccatgaggac ctcatgaaacactgtggtatagagttaactgaagatggtgctttagatggggacagtaat tttaccattcgagatcgactgatgtcgttggtggaaaaagtgactgacctgaagaacaag atggtcaacctgccaaaggaaaaaacagatagaaaacccagtactttacagcagttgatt tcagagacgatggttcgctgggctcaggagtcggttattgaggatccggagcttgtcaga gccatgtttgtcctgttgcaccgacagtatgatggcattggaggacaggtttgggctctc cccaagacttacacaataaactcggtttcaatcgaggacaccatcaacctcctcgctgct cttggtcagataagattgttgctgagtgtgcgtatgggaagagaggaggagaagctcatg ataagaggactgggtgatattatgaacaacaaggtgttctaccagcatcccaacttgatg agagctctgggaatgcatgagactgtcatggaggtcatggtgaacgtactcagtggagga gattctaaggaaattacctttcctaaaatggtggccaactgttgtcgttttctttgttac ttctgtcgaatcagccgtcaaaaccagaaagccatgtttgatcatctcagctacctgctg gagaacagcagcgttggccttgcatctccatcgatgcgaggatccacccctcttgatgtg gctgcagcatcagtgatggataacaatgagttggcccttgccctgagagagccagacttg gagaaggtggttcagtatctggctggctgcgggctgcagagctgcacgatgctggtgtat aaaggatatcctgacattggctggaaccctgtagaaggagaacgctaccttgacttcttg cgttttgctgtattttgtaatggtgaaagtgtggaagagaatgctaacgttgtggtgaaa cttcttatccgccgaccggaatgttttggccctgcacttcgaggagaaggtggtgatggg ttgttggccacaatggaagacgcaattaagatttcccttgatcccttaagagatggtcct tcctctgcatcagaaaggagcaatattcccaatgatgggttagatgaagaagacgacact atccacttgggaaatgccatcatgaccttctatgcagctctcattgacctgctgggacgt tgtggtcctgaaatgcatttgatacatgctggtaaaggtgaagcaatccgcatcagagcc attctaaggtccctcattcccattgaagatctggtgggcgtcatctgcattccattctct atgccaagtctagaaaaagattgggtggtgttggagccagacatgtcagctggcttttgt ccggatcataaagcggccatggtgctgtttttggaccgggtatatggtgtacaagaccgg aatttcctcctgcatctgctcgaagttggcttcttaccagacctcagagctgcagcttca ttggacactgtagcgcttagtgccacagatatggctcttgccctcaacaggtatttgtgc acagcagtattaccactgctgacgaaatgtgcgccactgttcgcggggaccgagccattc gcgtcactgatcgattccctccttcacacggtttaccgtctttcgaaaggctgctgcctt accaaagcccagagagattccattgaagagtgtcttctagcggtttgtggtaagctgagg ccttcaatgatgcagcatttgttgagcaggcttgtgtttgacattcccttgcttaatgaa cataccaagatgcctttgaagcttttgaccaatcactttgagtgttgttggaagtactac tgcctggctggaggctggggcagttttggtgctgcatctgatgaagagcttcacctctgc aggaaattattttggggaatatttgatgctctctctcataagccatatgaccaggagctg tttaaggttgcattgtcatgcctaagtgcagtggggggagctcttcctccagactatatg gagtccaactacatggccatgatggacaaacaatcatctatggatactgaaggaaacttc actccgcagcctgcagatactgccaatgtgactgtaccagataaactggacattttcatc gccagatatgcagagcataaccatgagaagtggtgtttcgaaaagttttcaagtggctgg tcatatggggaaaaagcatgtgaaatatccaggacccacaatttattaaagccttttaaa gcactcactgataaggataaagagttatattactggccaatcagagagtctctaaagacc atgctttcttggggatggagcatcaacaggatacgagagactgactctgccacgctgcat aacacatctaggaggatatcgcaagccagccagccgtcctttgaaggagcacagtgtttc aatcccagacccattgatatgagcaatgttacactgtccagagactcacagtcaatggca gagctgctcgcagagaactatcataacatctgggccaggataaagaaaattgatctagaa gccaaaggcggaggaaatgaccccttactagttccctttgatacactgactgccaaagag aaattaaaagacagacaaaaagcactagacatcctcaagttcctccagatcaatggttac actttgtcaagaggtgtgaagtcgcaggagttggacacaccagccatagagaaacgattt gcctacaccttccttgagcagctcatcaactatgtagaccaggcccatgatcacatgctg gagtttgacatgggaacaagacaaaggggagtaaagagtcctcatgaacagcagatgaag ttctttttaaaggttgtcttgccattggtggatcaatatttcagaaaccatcggctgtac ttcctatccacatccatccattccattagcaatggtggacatgcctccaacaaggaaaaa gagatggtgacaagtcttttctgcaaactgggagtacttgtcagaaataggatatcctta tttggtaataatgccacatccatagtcaactgtttgcaaatactgggtcaaagtctggat gccaggacagtgatgaagacaggcttggagtcagtcaaggcagcactgcagtcctacttc gacaatgcagcagagactctggggaagactcaagagaacctgaagcttggccaatttact cacagcaaagaacagcccagaggagtccctcagatcatcaactataccacctttggcctg cttccgatcctgtcttccttgtttgagcacgttggaaagaacaattttggagaagatctc atattggatgagatccaggtttcctgctacagaatccttaacagcctctactttctggga accaatgaaagcatatatgtagagagacatcgcccagcattaggaaaatgtttggctgct ttctcaacagccttccctgttgccttccttgaacctcacatcaacaagttcaacaacttc tcactctacaacagcaaaagtgctgaagacagaaatgctcttggtctgcccagccaggtc gtagaggtttgtccaatgattccaaatctggagaggtctctggaagagatcatcgaggtg gcagagtctggcatgaaatatactcaaatgccacatgtcatggaggtggttttaccagtt ttgtgcagctacatgtctcactggtgggaacacgggccggagaacaacccaaaccaggct gacagttgctgtacatctgtgacctctgaacatatgaacatattactcggaaacatcttg aagatcatctacaacaatttagggatagatgagggagcctggatgaaaaggctagctgtg ttttcacaaccaatcatcagcaaggccaaatcgcagttgctcaagacccactttctgcct ctcatgaagaaactcagaaaaaaagcagctgttgtgctggcggatgaggaacaagggaag gcagaggggaggggtgagatatcagaaactgagcttctcatcatggaccagttctctgtt cttgtcagagacctctacgccttttatccccttctaataagatttgttgactacaacagg gccacatggctgaaagagtctaatccagaggcagaggtgttgttccagatggtggcagaa gttttcatcttctgggcgaagtctcataactttaagagagaggaacagaattttgtggtt cagaatgaaatcaacaacatgtccttcctcatctcagattccaagtgtaagatgtcaaag ggaataggttccttccaggagaggaagaagttgcggagaaagggagaccaatattcattg cagaccagtctgatcgtggcaactctgaagcgactcctacctgtaggacttaacatttgt gttcctggcgaaaaagaactgattgctcttgcaaagaaccgattctcccagaaagatact gaggatgaagtgcggcaagtcattagaaacaacctgcatctacaaggaaagttgcaggac cctgctattaggtggcaaagggccttgtacagagacattctaaataactgtgatgacacc cctgaccccgagaagaatgtggaaagagttctggacattgctcatgtcctcttccacctc gaccaggttgagcatccccagcacagtaaaaaggctgtgtggcacaaattactgtccaaa cagagaaagagagctgtagttgcttgctttaggatggctcctctctacaatctgcccagg catcgggctgtcaacttgttcctccagggctatgaaaaatcctggattgaggcagaagaa cacttctttgaggataaactaatagaggatcttgctaaatccggcgaacaacaggcgttc gaggagatggagggagtgaaacacattgacccactacatcagctcatccagcttttcagt agaacagcccttatagagaagtgtaaactggatgaagatcatctctacatggcttacgct gatatcatggccaagagctgtcatgatgaagaagatgaagatggggaggaagtgaaaagt tttgaagagaaggagatggaaaagcagaagctgttgtaccagcaggaaaggcttcatgat cgcggcgctgctgagatggtacttcagaccattagtgcaagcaaaggtgaaatgggctcc atggtggcctcaactctaaaattgggcattgcaattctcaatggaggaaactcaacagta caactgaaaatgctggattatctgaagaacagaaaggatgtgggtttctttcagagtctt gctggcctcatggagtcatgcagtgttctagatctaaatgcatttgagagacagaacaaa gcagaaggcctgggaatgatcaccgaggagggatcagtcaactcagtcttggtttttggt gagaaggttatgcaggatgatgagtttacctgtgaccttttccgcttccttcagcttctc tgtgaaggacacaactcagatttccagaactacttaaggactcaaacagggaacaataca actgtcaacataatcatctcgactgttgactaccttctaagagtacaggagtctattagt gatttttactggtattactccgggaaagatgtaattgatgagcaggggcagaggaacttc tcaaaggcaattaacgtggccaagcaggttttcaacacgctcacagagtatatccagggt ccatgtactggcaatcagcagagtttggcccacagtcgtctgtgggacgctgtggttggg tttctacatgtctttgctcatatgcagatgaaattgtctcaggactcgagtcagattgag ttactgaaggaactgatggatctccagaaagacatggtggttatgttgctttcaatgatg gaggggaatgtggttaatgggaccattggaaagcagatggttgacatgctggtggaatca tcgaacaatgtagaaatgattctgaagttcttagatatgttcctcaagctgaaagatgta acctcttcagatgcctttaaagagtatgaccctgatgggaaaggtgtaatatccaagagg gacttccagaaggcaatggagaaccataagcactacacccagtctgaggctgatttcctt ctctcctgtgctgaaactgatgaaaatgaactcctggactatgaagaatttgtggagcgc tttcatgaaccagctaaggacattggcttcaatgtggcggttttgttgaccaacttgtca gagcacatgcctcatgacaaccggctgcacaccttcctggagctggcagaaagtgttctc aactacttccagccctacctgggtaggattgagattatgggcagtgccaagcgtattgag agggtctactttgagatcagtgagtccagtcgaacacagtgggagaaacctcaggttaaa gaatccaagcgccagttcatctttgatgtggtaaatgaaggaggcgagaaggaaaagatg gaattgtttgtgaatttctgtgaggacaccatctttgaaatgcaactggctgctcagatg tcagacactggcgagcgctcagctgtgaaagaggacagtgagcaagagaggccagatatg gacaatccagagacaagcttcttttcagttaccacggcccgcatggcactgacagcgctg cggtacagtttcatgatattgattaaggtgctgtccataaagagtttgaagaagcagatg aagaagctaaagagtatgacatcaaaagacatggtgacagccctggtttcattctactgg tctgcattgcagggcctttttcatatggcattcagtgtggttcgaggattttgcagaatt ttctacaataatatatttggaggtaacctggttgatggggccaagaggataaaggtgtct gagctactggctaacatgcctgaacccacccaggatggagtcaggttgaagggaaaggac aaagagagaaaatcatctaacaggagttcaatgaaggaggacctggcatacttggctgtc aataccagtgacactgagctgttgtcagacatttttggcctggacttacggagagaggga ggacaatataaaataagtcctcacaaccccaatgccagtctcactgaaattctcaactcc ccgcttcctcctccgcccccttgtgctgcctcagcagcacctcctcctgagctcagacaa atggatcagtccaagagcccttccttggaggagaagaaggaagaaacaacagaaaatgca tgtgaaacaaagaaaaggggtgaacatgaagagaaacaggagaagaatgtgaagatgaaa tcaaaggtgaaaaggcataagatgtcaaaggatgaacccgatttgcaggagtcagcagtc tcaaagaagatcgttgcgtatcagaggaaactcctgaactattttgctaggaatttttac aacatgaggatgctggctctattagttgcatttgccatcaacttcattctcctattctat aaggtttctaaatcctcatcagtggctgaggaagtgatcacaaacagcccaccagacagc accattcagtgggatccactgagtggtgagcctatggtggagaagaaagatggtgtaatg gatgacctcggagagcccttgaagttagctatggtccattttgtcttggaggagggcagc ggatacatggagcccacactgcggatcttggctatccttcacactgtcatctctttcttc tgcatcatcggatattactgtctcaaggttccattggtggtctttaagcgtgaaaaggag gttgccaggaagttggagtttgatggcctttacataacagagcagccatctgaagatgat atcaaaggacagtgggacagactggttatcaacacacaatctttcccgaacaactattgg gataaatttgtgaagcgaaaggtaatggataagtatggggaattttatggtcattaccgg atcaacgagcttctgggattggacaaggctgctctggacttcagtggtgctcataaaaaa agaaaacccagaaaagacacctacctggctgctgtgctgaactccattgatgtcaaatac cagatctggaagctgggagtggtgttcactgacaattcgttcctgtatctggcctggtat atgacgatgtccatcctgggtcactacaacaactttttctttgctgcacatctgcttgac attgctatgggtttcaagacactgcggaccatcctgtcctcagtgacgcacaatggcaaa cagctggtgttaacagttggcctattagcagtggtggtgtatctgtacacagtagtagcc ttcaacttcttcagaaagttctacaacaagagtgaagatggagaattacctgatatgaaa tgtgatgatatgttgacttgctacatgttccacatgtatgttggtgtgcgagcaggggga ggcatcggtgaccagattgaggacccagcaggagacgaatatgagatgtatcgcatcata tttgacatcaccttttttttctttgtcattgtaatccttctggcaatcatccaaggttta atcattgacgcttttggagaactgcgggatcaacaagaacaagtgaaagaagacatggag acaaaatgttttatctgtggaataggcaatgactactttgatacagtgccacatggcttt gagacacacactctacaggagcacaacttgtccaattacctattctttgtgatgtatctt atcaacaaagatgaaacagagcacacaggccaggaatcttatgtatggaagatgtaccag gagcgttgctgggagttcttcccagctggcgattgtttccggaaacagtatgaagatcaa ctcaactga

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