KEGG   Phycodurus eques (leafy seadragon): 133417636
Entry
133417636         CDS       T09682                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
pee  Phycodurus eques (leafy seadragon)
Pathway
pee04010  MAPK signaling pathway
pee04012  ErbB signaling pathway
pee04020  Calcium signaling pathway
pee04510  Focal adhesion
pee04520  Adherens junction
pee04530  Tight junction
Brite
KEGG Orthology (KO) [BR:pee00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    133417636 (erbb2)
   04012 ErbB signaling pathway
    133417636 (erbb2)
   04020 Calcium signaling pathway
    133417636 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    133417636 (erbb2)
   04520 Adherens junction
    133417636 (erbb2)
   04530 Tight junction
    133417636 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pee01001]
    133417636 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pee04147]
    133417636 (erbb2)
   04090 CD molecules [BR:pee04090]
    133417636 (erbb2)
Enzymes [BR:pee01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     133417636 (erbb2)
Protein kinases [BR:pee01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   133417636 (erbb2)
Exosome [BR:pee04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   133417636 (erbb2)
CD molecules [BR:pee04090]
 Proteins
  133417636 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Pkinase GF_recep_IV Furin-like TM_ErbB1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 133417636
NCBI-ProteinID: XP_061561504
LinkDB
Position
19:4198228..4217267
AA seq 1307 aa
MEAVRSLLLLGAVLLRGSGSLAREVCLGTDMKLALPSSLDKQYETLRLLYTGCQVVHGNL
EITHLHGDLDLSFLQGIVEVQGYVLVAYVSVSLVPLDNLRIIRGSQLYNSSYALVVQDNT
RGEKVGLGTLRLRSLTEILLGGVYIWGNTQLCFPDPQNIVWRDTLDEQNIHAGPHRLQPR
ASNCSSCSPACKNSCWGETAQDCQTLTRISCASGCQRCKGPLPNDCCHMQCAAGCTGPKD
SDCLACRHFNDSGVCKDNCPPPTSYDPVSFQTKLNPDKKFNFGATCVKTCPYNYLAMDVA
CTLVCPKANQEVIISNPDGNETQKCEKCEGECPKVCYGLGMDNLGVMDNNGVTMVTSSNV
EQFSACKKIFGSLAFLPQSFIWDPVTNTSGLALEQLSAFKNLEEITGYLYIDAWPEDWTD
LTVFENLKVIRGRMLYKGVFSLAVQNLHIQSLGLRSLRSISGGLILLHNNSQLCYTNSLP
WSSLLHPTQGPHYIVNNNQDPQLCEAEGRVCHPLCKDGCWGPGPSQCVSCKTFRRGTECV
EQCDLHQGPAREYIDGSSCVACHAECRPLNGSLTCRGRAVCVCVCVCVRAFPQGADQCAE
CQNFQDGESCVEHCPSGVKEDQHTVWKYSNATGHCLPCNTNCTLSCTQMDERGCPIHPKT
GPGTTIAAAVGGVVLFFILLALLVFYLRRHKKLKKKETLRRILQEHELVEPLTPSGASPN
QAQMRILKETELKKLRVLGAGAFGTVYKGVWTPDGENVKIPVAIKVLRENTSPKANKEIL
DEAYVMAGVASPYVCRLLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQ
IAKGMNYLEEVRLVHRDLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKW
MALESILHRKFTHQSDVWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGERLPQPLICT
IDVYMIMVKCWMIDPDSRPRFKDLVSDFSAMARDPPRYVVIQNDEQMSMSSPVDSQFFRM
LLEEDGNNMRELLDAEKYLVPQPNLYPRPQGDGAQSNGPSRHQSYRSRDQGLEVEPPMAA
AAPRSMYSSLSTLGRSQYPTLPVGTAASNGTWTPHYPTLARSPSAGGQSDSVFLDGPPDD
PSLPPASPGRYCKDPTYGSQGELETDGPNGFLHPPHLHHSLPRRSHGYNRNHALPEYVNQ
EVQEARPERPTTLPRKISKVDRRLPNGLSSGHSVENPRYLVPSTSPAFDNPYYLDLVAKA
KAVAGATPADGPAEPERDVPRQVNGFVTPTAENPEYLGLADTWSGYT
NT seq 3924 nt   +upstreamnt  +downstreamnt
atggaggcggtgagaagtttgctgttgctcggggccgtgctgctccgagggtccggctcg
ctggccagggaagtgtgccttggtacggacatgaagctggccctgccttcgagcctggat
aaacaatacgagaccttgaggctactttataccggatgccaggtcgtccacggcaacctg
gagattacgcaccttcacggagacctggatctctccttccttcaggggattgtggaggtg
caaggctatgtgctagtggcttacgtctcagtgagcctagtgcctttggacaacctccgg
attatccgaggcagccaactgtacaattccagctatgctctggtggtgcaggataacact
cggggtgaaaaggttggactcgggacacttcgtcttcgcagcctcacagagatcctgttg
ggcggggtctatatttgggggaacacccagctttgcttccccgacccccagaacattgtg
tggagggacaccttggatgagcagaacatccacgccggcccacaccgactgcagcccagg
gcgtccaactgttcaagttgctcacctgcatgcaaaaacagctgttggggagaaactgca
caggattgccaaaccttgactcgtatcagttgtgcgtcaggctgccagcggtgtaaaggc
cctctgcctaacgactgctgtcacatgcagtgcgccgccggatgcacaggacccaaagac
tcagactgtctggcgtgccgacatttcaacgacagcggcgtttgtaaggacaattgtcct
ccacccaccagctacgacccggtcagctttcagaccaaactcaacccggacaaaaaattc
aacttcggagccacctgcgtcaagacgtgtccatataactacctagcgatggatgtagcc
tgcactttggtttgccccaaagccaaccaggaagtcatcatctccaatcccgatgggaac
gagacgcaaaaatgtgaaaagtgtgaaggagagtgtccaaaagtgtgttatggcctgggt
atggacaaccttggcgtcatggacaacaacggcgtcaccatggtaacctcttcgaatgtg
gagcagttcagtgcttgtaagaagatttttggcagtttggccttcctccctcagagcttt
atttgggacccagtgaccaacacatccggccttgctctcgagcagttgagtgccttcaag
aacctggaggagattacaggttatttgtacattgatgcctggccagaagactggactgac
ctgactgtgtttgagaacctgaaggtgatccgaggcaggatgctctacaagggtgtattt
tccctggccgttcagaacctacacattcagtctctcgggctgcgttcgctgcgcagcatc
agcggaggtttgatcctgttgcacaacaactctcagctgtgctacaccaattcattgccc
tggagcagcctcctccaccccacccaagggccccactacatagtgaacaacaaccaagac
ccccaactctgtgaggcagaggggcgtgtttgtcacccgctgtgtaaggacggctgttgg
gggccggggcccagccagtgtgtgtcctgcaagactttccgacgtggcaccgagtgtgtt
gagcagtgtgaccttcatcaggggcctgcacgggaatacattgatggatcctcgtgtgtc
gcctgtcacgccgagtgtcggcctctcaatggctcgctcacatgtcgtggccgggctgtg
tgtgtgtgtgtgtgtgtgtgtgtgcgtgcgtttccgcagggtgcggaccagtgcgccgag
tgtcagaacttccaggatggcgagtcctgtgtggagcattgccccagcggtgtgaaggag
gaccagcacaccgtgtggaagtacagcaatgccacaggacactgtctgccctgcaacacc
aactgcacgctgtcatgcactcagatggatgagagaggctgcccaatccatcccaagaca
ggaccgggcacgactattgcggcggcagtgggtggtgtggtgctcttcttcatcctcctc
gctctgcttgtcttctacttgaggagacataaaaagctgaaaaagaaggagaccctgagg
aggatcctgcaggagcacgagctggtggaacctttgacaccaagtggggcctcacccaat
caggctcagatgcgcatcctgaaggaaacggagttaaaaaagctcagagtgcttggcgct
ggagcttttggtaccgtttacaagggagtgtggactcccgatggggaaaacgttaaaatt
ccggtggccatcaaggtgttgcgggagaacacctcgccaaaagccaataaagagatcctt
gatgaggcatacgtgatggcaggggtggccagtccctacgtgtgtcgcctgctgggcatt
tgtttgacttccacggtgcagctggtcactcagctcatgccgtacggctgcctcctcgac
tacgtccgggagaacaaggatcgcatcggctcccagttcctcctcaactggtgtgtccag
attgccaaggggatgaactacctcgaggaggtgcgcctcgtccacagagatttggcagcc
cgcaacgttctggtgaagaacccgaaccacgtgaagatcacagacttcggcttggcacgc
ttgctcgatattgacgagaccgaatatcacgccgacggggggaaggttccgattaaatgg
atggcactggagtctatcctgcacaggaagtttacacatcagagtgacgtttggagctat
ggggtgaccgtgtgggagctgatgacattcggcgccaaaccgtacgacatgatcccggcc
agagaaatcccagatgttctggaaggcggggagcgcctcccgcaacccctcatttgcacc
atcgacgtctacatgatcatggtcaaatgttggatgatcgacccagacagccgacccaga
tttaaagatctggtgagtgatttttccgccatggccagggacccacctcgctacgtcgtc
attcagaacgacgagcagatgagcatgtccagcccggtggacagtcagttcttccgaatg
cttctggaggaggacgggaacaacatgagggaactgctggatgccgagaagtatctggtg
cctcaacccaacctctatcccaggcctcagggagacggggcgcagtcaaacgggccgtcc
aggcatcagtcatacaggagcagagatcagggcttagaagttgagccccccatggctgcc
gcagcccctcgtagcatgtactcctccctcagcactctgggccgcagccagtaccccacc
ttaccagtaggaaccgccgcctccaacggtacgtggacccctcattaccccacgctggca
cgcagcccctccgccggcggccagtccgactcggtcttcctggacggacccccggacgac
ccctcgctgcccccggccagccccgggcgctactgcaaggaccccacctacgggagccag
ggcgagctggagacggacggccccaacgggttccttcatcctcctcatcttcatcactcg
ctgcccaggagaagtcacggctataatcgcaaccacgccttgccagagtacgtcaatcag
gaagtccaagaggccagaccggagcggcccaccacgcttcctcggaaaatctccaaagtg
gacagacgcctgccgaacggcttgagttcaggccacagtgtggagaaccccaggtacttg
gtcccctccacctcacctgcctttgacaacccgtactacctggacctcgtggccaaagca
aaagcggtcgccggggcgacgccggcggacggcccggcggaaccggagcgggacgtgccg
cgacaagtcaacggatttgtcactcccacggccgagaacccggaatatctgggcctggcg
gacacctggagtggatacacatga

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