Candidatus Sodalis pierantonii: SOPEG_1355
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Entry
SOPEG_1355 CDS
T03006
Symbol
thrA
Name
(GenBank) Aspartokinase / Homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pes
Candidatus Sodalis pierantonii
Pathway
pes00260
Glycine, serine and threonine metabolism
pes00261
Monobactam biosynthesis
pes00270
Cysteine and methionine metabolism
pes00300
Lysine biosynthesis
pes01100
Metabolic pathways
pes01110
Biosynthesis of secondary metabolites
pes01120
Microbial metabolism in diverse environments
pes01230
Biosynthesis of amino acids
Module
pes_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pes_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pes00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SOPEG_1355 (thrA)
00270 Cysteine and methionine metabolism
SOPEG_1355 (thrA)
00300 Lysine biosynthesis
SOPEG_1355 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SOPEG_1355 (thrA)
Enzymes [BR:
pes01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SOPEG_1355 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SOPEG_1355 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AHF73607
UniProt:
W0HM85
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All DBs
Position
1405048..1407498
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AA seq
816 aa
AA seq
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MRVLKFGGTSVANAERFIRVADILESNSRQGQVAAVLSAPAKITNHLVMMIDRTLNGIDI
QPNILDAEQIFTRLLDGLAAAQPEFDHPALRSQVEQEFAQLKQLLHGISLLKYCPDSVNA
AIISRGEKLSIALMEALLRARGFNVTVIDPVEKLLAQGGYLESTVDIAESTRLINDAAIP
ADHIILMAGFTAGNERGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPNRV
PDARLLSQLSYQEAMELSYFGAKVLHPRTIVPIAQFQIPCLIKNTTNPQAPGTLIGPTSG
EEGNPVKGITHLNNMAMINVSGPGMKGMIGMAARIFAAMSRAGSSVVLITQSSSEYSISF
CVPQHELAGARRALEEEFYLELKDGLLEPLDVISRLAIISVVGDGMRTQRGLSAKLFAAL
ARANINIIAIAQGSSERSISVVVDNDSTTTGVRVAHQMLFNTDQVIEVFVIGVGGALIEQ
IRRQHAWLKDKHIDLRVCGIANSRALLTNVHGIDLANWQGALAEAREPFNLGRLIRLVKE
YHLLNPVIVDCTSSEAVANQYADFLADGFHVVTPNKKANTASMDYYHQMRAAAATSRRKF
LYDTNVGAGLPVIENLQNLLNAGDELTRFSGILSGSLSFIFGKLDDGMSLSAATLLARGN
GYTEPDPRDDLSGMDVARKLLILAREAGYTLELADIDVEPVLPASFDAGDDVETFLARLP
ALDDEFAARVAKAHAEGQVLRYVGSIDEGRCKVKIDAVGANDPLFKVKDGENALAFSTRY
YQPLPLVLRGYGAGNDVTAAGVFVDLLRTLSWKLGV
NT seq
2451 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtactgaaattcggcggtacctccgtcgccaacgcggagcgttttatccgcgtc
gccgatatccttgagagtaatagccgccagggacaggtggcggcggtattatccgcgccg
gccaaaatcaccaaccacttggtcatgatgatagaccgtacgctcaacggcattgatatc
cagccgaatatccttgacgccgaacagatctttacccgactgttggacgggttggctgca
gcccagccggagtttgatcatccggcgctgcgtagccaggtggagcaagagttcgcacag
ctcaaacagttattgcacggcatttcactgctgaaatactgccctgatagcgttaacgcc
gcgatcatcagccgcggcgaaaaactttccatcgcgctaatggaagcgctattacgcgcc
cgcggtttcaacgtgacggtcatcgacccggtggagaagctgctggcgcaggggggctat
ctggaatcgacggtggatatcgccgagtccacccggctcatcaacgatgccgccatcccc
gccgatcacatcatcctgatggcgggctttaccgccggtaacgagcgcggtgaactggtg
gtgctgggccgcaatggatccgattactcggcggcggttctggcggcctgtctgcgcgcc
gattgctgcgaaatctggacggacgtggacggcgtttatacctgcgatccgaatcgggtg
ccggatgcgcgtttactcagtcagctttcctatcaggaggcgatggaactttcctacttc
ggcgccaaggttcttcatccccgtaccatcgtccccatcgcgcagttccaaattccctgt
cttatcaaaaacaccaccaatcctcaggctcccggcacgttaatcgggcccaccagcggc
gaggaaggtaacccggtcaaaggtattacccatctgaataatatggcgatgatcaacgtt
tctggcccgggaatgaaaggcatgatcggcatggcggcgcggattttcgcggccatgtcg
cgcgccggcagctccgtggtgctgattacgcaatcctcgtcggaatacagcatcagtttt
tgcgtgccgcagcatgagttggcgggtgcccgccgggcgctggaggaggaattctacctg
gagctgaaagacggcctgctggagccgctggatgtgatttcccgcctggcgattatttcg
gtggtcggcgacggaatgcgaacccagcgcggtctgtccgccaaactttttgcggcgctg
gcgcgcgccaacatcaacatcatcgctatcgcccagggatcctccgagcgttccatctcg
gtggtggtggacaatgacagcaccaccaccggcgtacgggtcgcgcatcagatgctgttc
aataccgatcaggttattgaagtcttcgtcatcggcgtcggcggcgcgctgatcgagcag
atccgccgtcagcacgcgtggctaaaggataagcatatcgacttgcgggtatgcggaata
gccaactcgcgcgctctgctgaccaatgtgcacggcatcgacttggctaactggcagggg
gcgttggcggaggcgcgcgagccgttcaacctggggcggctgattcggctggtgaaagag
tatcacttgcttaacccggtcatcgtcgattgcactagtagcgaggcggtggccaaccag
tatgcggatttcctggcggatggcttccacgtggtgacgccaaataaaaaagccaatacc
gcctcaatggattattaccatcaaatgcgcgccgcagccgcgacctcgcgccgtaaattt
ctttatgataccaacgtcggcgccggtttgccggttatcgagaatttacagaacttattg
aatgccggtgacgagttgacccggttttccggtattctttccggctcgctgtcgtttatt
ttcggcaaactggatgacggtatgtcgctgtcggcggcaacgcttttggcgcgcggcaac
ggctacaccgaacccgatccgcgcgatgatctgtccggtatggatgtggcgcgcaaactg
ctgattttggcgcgcgaggcggggtatacgctggaattggcggatattgatgtcgagccg
gtgctcccggcgagctttgacgccggcgacgacgtggagacgttcctggcgcgtctgccg
gccctggatgatgaattcgccgccagagtggcgaaggcgcacgccgaaggtcaggtgctg
cgctatgtgggcagcattgacgaaggacgctgtaaagtcaaaatcgacgcggtgggcgcc
aacgacccgttgttcaaagtaaaagacggggaaaacgcgctggcgttctcaacccgctat
tatcagccgttaccgctggtgctgcgtggctatggcgccggcaatgatgtcaccgccgcc
ggcgttttcgtcgatcttttacgcacgctgtcatggaagttgggagtttaa
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