Pedobacter endophyticus: IZT61_10440
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Entry
IZT61_10440 CDS
T07452
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pex
Pedobacter endophyticus
Pathway
pex00260
Glycine, serine and threonine metabolism
pex00261
Monobactam biosynthesis
pex00270
Cysteine and methionine metabolism
pex00300
Lysine biosynthesis
pex01100
Metabolic pathways
pex01110
Biosynthesis of secondary metabolites
pex01120
Microbial metabolism in diverse environments
pex01230
Biosynthesis of amino acids
Module
pex_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pex00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
IZT61_10440 (thrA)
00270 Cysteine and methionine metabolism
IZT61_10440 (thrA)
00300 Lysine biosynthesis
IZT61_10440 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
IZT61_10440 (thrA)
Enzymes [BR:
pex01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
IZT61_10440 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
IZT61_10440 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
ACT
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
QPH41636
UniProt:
A0A7S9L3S5
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All DBs
Position
2600161..2602611
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AA seq
816 aa
AA seq
DB search
MKVLKFGGTSVGSAENIKTLLNIVAKEKLQSNPVVVLSAMSGVTNLLTDMAESAERGEDY
DASLKEIEAKHFAVIRSLLPAAAQNPVFTRLKIFFNELEDLLQAVTNLRELSLQTKDQIL
SYGERCSSFMIAHIASQQFGEAMYVNGSELIKTDSNFGQAKVDTKLTEMLINNFYEANKS
KVLFVTGFIASNASGRITTLGRGGSDYTAAVWGAALNAEEIEIWTDVNGMMTADPRIVKK
AFSLPELSYTEAMELSYFGAKVIYPPTMIPAFMKKIPIVIKNTFKPDFSGTYIKSDVKVS
SLPIKGISSIDHISIINLTGSGMVGKAGFSGRLFSLLSREQINVVLITQSSSEHSITFAV
KPTDAEDAIALIKKEFELELDAKKLELPVVEKDLAVLAIVGENMKHTPGMSGRLFNALGR
NGINVRAIAQGSSEYNISVIISKVDLSKAVNAVHDAFFTDLKRTLNIFCLGTGNIGKTLF
NQLKEQRPFLAENNDLQVKVAGISNTRKMIFEADGLSLDNWETDLNTNGEQADLAGFVER
MKAMNLPNCVFVDNTASESPIEFYQGIFESSISVVTCNKKGNSADFAQYKSFKDTARKFG
VDFYYETNVGAGLPIIRTLKELMMSGDKVARIEAILSGTISYIFNNFKGEAGFYETVKEA
QELGYTEPDPRDDLNGMDFMRKMLILARDAGYPLEAKDVKIDNILPEACLKATSVEDFYA
ELQKNASYFEDLKNKATSDGKVLRYIGKLEDGNVEISLQMVDDSHPFYMLSGSDNIISFT
TDRYKSRPLVVKGPGAGAEVTAAGVFADIINVGTLS
NT seq
2451 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtattaaaattcggcggcacatccgtaggttcggccgagaacattaaaacgcta
ctaaacatagtggccaaagaaaaattacagagcaatccggtagttgtattatcggcaatg
agtggcgtaactaatttgcttaccgacatggccgaaagtgcagagcggggcgaagattac
gacgcaagtttaaaagaaattgaagccaagcattttgccgtaattcgttcgcttttacca
gctgcggcacaaaacccggtgtttacccgcttgaaaatcttttttaatgaacttgaagat
ttgttgcaggccgtaaccaacctccgcgaactgagcctgcaaacgaaagatcagatttta
agctatggcgagcgttgttcatcatttatgattgcgcacattgcctctcaacaatttggc
gaagcaatgtatgtaaatggatcggaactgattaagacagacagcaacttcggccaggca
aaggttgacactaaacttactgaaatgttgatcaacaacttttacgaggccaataaaagc
aaggttttgtttgttacaggtttcattgccagcaatgcgtcagggcgcataactacgctg
ggccggggcggttctgattatactgctgcggtttggggcgctgcgctaaacgctgaggaa
attgaaatctggacggatgtaaatggcatgatgaccgccgatccgcgaattgtaaaaaag
gctttctcattacccgagctgagttacaccgaggccatggaactgagctattttggggcg
aaggtgatttatccaccaacgatgatcccggctttcatgaaaaaaatcccgatcgttatc
aaaaacacctttaaacccgatttttcgggaacctatataaaaagtgacgtaaaagtttcg
agtttgccgattaagggtatctcatctatcgatcacattagcatcattaacctcactggt
agcggaatggtgggcaaggccggcttcagcggccgtttattctccctcctttcccgcgag
caaattaacgttgtactgattactcaatcatcgtcagagcatagcatcactttcgccgtt
aagccaactgatgcggaggacgcaattgcattgataaaaaaggaatttgaactcgaactc
gatgccaaaaagctagaacttccggtagtagaaaaggatttggcggtgttggctattgta
ggcgaaaacatgaaacatacgccaggcatgagcggcagattgtttaacgccctgggcaga
aacggtatcaatgtgagggcgattgcacaaggatcttccgaatacaacatttcggttatc
atcagcaaagtcgacctttcgaaagccgtaaatgcagttcacgatgcgttttttaccgat
ctaaaacgaacacttaacattttctgtttgggaacgggaaatattggcaaaacattgttt
aaccaactaaaagagcaaagacctttccttgcagaaaacaacgatttgcaggtgaaagtt
gccggaatcagcaatacgcgtaaaatgatttttgaggccgatggtttatcgctcgacaat
tgggaaacggacctgaacaccaatggcgaacaggcagatttagcaggttttgtagagcgt
atgaaagcaatgaatttgccaaactgtgttttcgtagacaacacggcttctgaatctccc
atcgaattttaccaaggtatttttgaaagcagcatttcggtagttacgtgtaataaaaaa
ggaaattcggccgattttgcgcagtacaagtcgtttaaagataccgcccgcaagtttggt
gtcgatttttactacgaaactaacgttggtgcgggcttaccgattatccgtacgctaaaa
gaactgatgatgagcggcgataaggtggcccgtattgaggcgattctttcaggaacaatt
tcttacatttttaataactttaagggtgaagccggcttttacgaaacggttaaagaagca
caagaacttggctacacggaacccgatccacgcgacgatttgaatggcatggactttatg
cgtaaaatgctgattttggcccgcgatgcgggttatccattggaagccaaagatgtgaag
atcgacaatattttgcccgaggcttgtttgaaggcaacatcggtagaagatttttatgcc
gagttacaaaaaaatgcgagttattttgaggacttaaaaaacaaagcaacaagcgatgga
aaagtgttgcgctacattggcaaactggaagatgggaacgtagaaattagcctgcaaatg
gttgatgacagccatcctttctatatgctttcgggaagcgacaacattatctcgtttaca
accgaccggtataaatctcgtccgttggtggtgaaaggtcccggagctggggcagaagtt
acagctgccggtgtttttgccgatattatcaacgtgggtacgctaagctga
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