Plasmodium falciparum 3D7: PF3D7_1345700
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Entry
PF3D7_1345700 CDS
T00095
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pfa
Plasmodium falciparum 3D7
Pathway
pfa00020
Citrate cycle (TCA cycle)
pfa00480
Glutathione metabolism
pfa01100
Metabolic pathways
pfa01110
Biosynthesis of secondary metabolites
pfa01200
Carbon metabolism
pfa01210
2-Oxocarboxylic acid metabolism
pfa01230
Biosynthesis of amino acids
pfa04146
Peroxisome
Module
pfa_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
PF3D7_1345700
09106 Metabolism of other amino acids
00480 Glutathione metabolism
PF3D7_1345700
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
PF3D7_1345700
Enzymes [BR:
pfa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
PF3D7_1345700
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
814208
NCBI-ProteinID:
XP_001350171
PlasmoDB:
PF3D7_1345700
UniProt:
Q8I6T2
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Position
13:complement(1828283..1829689)
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AA seq
468 aa
AA seq
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MGKHIRILKNQYLQFMSKRCIQSKAAFNICGKINVENPIVELDGDEMTRIIWKDIKEKLI
LPYVNLKIKYFDLSIENRDKTNDQVTIEAAEEIKKTSVGIKCATITPDAARVKEFNLKEM
WKSPNGTIRNILDGTVFRTPILIKNIPKLVPNWKKPIVIGRHAYADQYKQKSLKIEKSGK
FEIVFTPDDNSQVLRETVFHFKSPGVCLGMYNTEESIRNFALSCFQYALDLKMPVYMSTK
STILKIYDGLFKDIFDEIYEKQFKKSFEQHNLWYEHKLIDDMVAQVLKSEGGFLWACKNY
DGDIQSDAVAQGYGSLGLMSSVLLCPDGVTCVSEAAHGTVTRHYRAYQKGEKTSTNPIAS
IFAWTKGLEHRAKLDKNDNLKQFCYALEKACIETVEDGLMSKDLAGCIKGIKNVTEKDYI
FTQDLINAINEKLKLKILQNQSKNDPQATSYKLKNDNWNFYAPQEHST
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagcatatacgaattttaaaaaatcaatacctacaatttatgtcgaagagatgt
attcaaagcaaggcggcttttaacatatgcggtaaaattaacgtagaaaaccctattgta
gagttagatggagatgaaatgactagaataatttggaaagatataaaagaaaaattaatc
ttaccatatgttaacttaaagataaaatattttgatttatctattgaaaatcgagataag
actaatgatcaagttaccatagaagctgctgaagaaataaaaaaaacttcagtaggtata
aaatgtgcaactataacacctgatgctgcaagagttaaagaatttaatttaaaggaaatg
tggaaaagtccaaacggtactataagaaatatattagatggtactgtttttagaacacct
atacttattaaaaatatacctaaactagtacctaattggaagaaaccaattgttatagga
agacatgcatatgctgatcaatataaacagaaatctttaaaaatcgaaaaaagtgggaaa
tttgaaattgtatttactccagatgataattcacaagtacttagagaaactgtgtttcat
tttaaatctcctggtgtatgtttaggtatgtataatacagaagaatctatacgaaatttt
gcattgtcttgttttcaatatgctttagatcttaaaatgccagtttatatgagtactaaa
agtactatactaaaaatatatgatggtttatttaaagatatttttgatgaaatttatgaa
aaacaatttaaaaaatcttttgaacaacataatttatggtatgaacataaactaattgat
gatatggttgctcaagtattaaaatcagaaggtggatttttatgggcatgtaaaaattat
gatggtgatatccaatctgatgctgttgctcaaggttatggaagtttaggattaatgtca
tctgtgttattatgtccagacggtgttacgtgtgtttcagaagctgcccatggtaccgtc
actagacattatagagcttatcaaaagggagaaaaaacatcaacaaatcctatagcctct
atttttgcatggaccaaaggattagaacacagagcaaaattagataaaaatgataattta
aaacaattttgttatgctttagaaaaggcatgtatcgaaacggtagaagatggattgatg
tctaaagatctagcaggatgtattaaaggtattaaaaatgttactgagaaggattatatc
tttactcaagatttaatcaatgctattaatgaaaaactaaaattaaagatacttcaaaat
caatccaaaaatgatccacaagctacttcatataaattgaaaaacgataactggaatttt
tatgctccccaagaacattcaacataa
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