Pseudomonas fluorescens A506: PflA506_4212
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Entry
PflA506_4212 CDS
T02114
Symbol
leuA_1
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
pfc
Pseudomonas fluorescens A506
Pathway
pfc00290
Valine, leucine and isoleucine biosynthesis
pfc00620
Pyruvate metabolism
pfc01100
Metabolic pathways
pfc01110
Biosynthesis of secondary metabolites
pfc01210
2-Oxocarboxylic acid metabolism
pfc01230
Biosynthesis of amino acids
Module
pfc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pfc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
PflA506_4212 (leuA_1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PflA506_4212 (leuA_1)
Enzymes [BR:
pfc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
PflA506_4212 (leuA_1)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AFJ54694
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Position
complement(4648328..4650022)
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AA seq
564 aa
AA seq
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MMLKDPSRKYRHFTTANLPDRTWPSTVQVAAPTWCSVDMRDGNQALIEPMNAERKRRFFD
LLVKVGFKQIEVGFPAASQTDFDYVRELIESGAIPDDVTIQVMTQARSHLIERTFEALKG
APRAIVHVYNATAPVFRDVVFNVDKAGCIEIATQATREIKQHMDANPDTQWTFQYSPETF
CFTELDFALQVCEAVTDTFGPTPSNKMILNLPTTVEVSTANVFADQIEWFCRHFSRRDSV
VISVHPHNDRGTGVSTAEQACLAGAERVEGTLFGNGERTGNVDILTLAMNLYTSGIDPQL
DFSDILHVQREVEFCNQLPTHPRHPYAGELVFTAFSGSHQDAIKKGFAARQANPQGMWEV
PYLPIDPADMGRSYEAVIRVNSQSGKGGVAYLLEQHGIVMPRRLQMEFSSLVQQEADGSG
QEISGEMILACFTRHYLEQGKPYALRAPKLVSEGDVTYLEATLEQGTQRIDLSGEGNGPL
AALVDAFAQRGIHFDIADYHEHATRDGAQAEALAYVEIRVGNQLLFGAARDGSSLLASLK
AVTSAVNRASRLGLLSLVNAAVPS
NT seq
1695 nt
NT seq
+upstream
nt +downstream
nt
atgatgctcaaggacccttcccgcaaatatcgccacttcaccacggccaacctgccggat
cgcacatggcccagtactgtccaggttgccgctcctacctggtgcagtgtggatatgcgc
gatggcaaccaggcgttgatcgagccgatgaatgccgagcgcaagcggcgtttcttcgat
ttgctggtgaaggtcggtttcaagcagatcgaggtgggctttcctgccgcttcgcagacc
gactttgactatgtccgtgagctgattgaaagcggtgcgattcctgatgatgtgacgatt
caggtcatgacccaggcgcgcagccacctcatcgagcgcacgtttgaggcgttgaagggc
gcgcctcgcgccatcgtgcatgtttacaatgcgacggcgccggtgttccgggacgttgtc
ttcaatgtggacaaggcgggctgcatcgagattgctacccaggcaactcgggagatcaag
cagcacatggacgcaaaccccgatacgcagtggacgttccagtattccccggaaaccttt
tgcttcaccgagctggattttgcactgcaggtgtgtgaagcggtgacagatacgttcggc
ccgaccccgagtaacaagatgatcctgaatctgcctaccactgtggaggtgtctaccgcc
aatgtcttcgccgaccagatcgaatggttctgccggcacttcagtcgccgggacagtgtg
gtcatcagcgtgcatccgcacaatgatcggggcactggggtctccaccgcggagcaggcg
tgcctggctggtgccgagcgtgtcgagggcacgttgttcggtaacggtgagcgcactggc
aacgtagatatcctcacgttggcgatgaacctctacaccagcggcatcgatccgcagttg
gatttctccgacatcctgcacgtccagcgtgaggtggaattctgcaatcagttgccgacc
catcctcgtcacccttacgccggtgagttggtgtttaccgcattctccggctcgcaccag
gacgcgatcaagaaaggctttgcggcgcgccaggccaatccacagggcatgtgggaagta
ccgtacctgcctatcgatcctgccgatatgggccgtagctatgaagcggtaattcgcgta
aacagccagtcgggcaaggggggcgtggcctatctgttggagcagcacggcattgtgatg
ccgcgtcgcttgcagatggagttcagcagcctggtacaacaggaagcggatggctccggc
caggaaatcagtggcgagatgatccttgcctgcttcacccggcattacctggagcagggc
aagccttacgcgttacgagcccccaaactggtgagcgagggcgatgtgacttacctggag
gccacccttgaacaaggcacacagcgcatcgacttgagtggcgagggcaacggcccgctt
gcggcgctggtcgatgcgtttgcccaacgtggcattcattttgatatcgccgattaccac
gaacatgccacccgtgacggtgcccaggctgaggcgttggcctatgtggaaattcgcgtg
ggcaaccagttgctgttcggcgccgctcgtgatggcagtagccttctcgcttccctcaaa
gcggtcaccagtgcggtcaatcgtgcatcgcgcctgggcttgctcagcctggtgaatgct
gcggtgccgtcctga
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