Perca fluviatilis (European perch): 120559016 Help Entry 120559016         CDS       T11622                                  Symbol ubr4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism pflt  Perca fluviatilis (European perch) Brite KEGG Orthology (KO) [BR:pflt00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pflt04121]     120559016 (ubr4) Enzymes [BR:pflt01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      120559016 (ubr4) Ubiquitin system [BR:pflt04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     120559016 (ubr4) SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4_TPR UBR4_Ub UBR4 zf-UBR_1 zf-UBR DUF7637 Motif Other DBs NCBI-GeneID:  120559016 NCBI-ProteinID:  XP_039656374 LinkDB All DBs Position 5:26149350..26212156 Genome browser AA seq 5127 aa AA seqDB search MASSGGDGEHEWTAAVRPLLSASYTAFETKELPQLIGSIINSESDILHHDKQYEPFYSSF VALSAHYITTVCGQIPRNQLLSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLC IGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELPSAVNPELRQKEVQMNFFNQL TSVFNPDLTTILASPSAAHMQAESDCDDQTTDQAIQAKMKNAFVSQNVSSLQELGGSEKL LRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLP VLEPLTPGRLLDMTVLALSCLYAGVSVATCMAILQVGSGLQLRSTSTGTKEEDYENDAAT IVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLYLILNLSPTALADKGKEK DPLAALRVRDIAARTKDGAGSPKLGPGKGHQGFGVLSVILANHAIKLLTSLFQDLQVEAL HRGWASDGPPAELNIMAQSTSIQRVQRLIDSVPLTNLLFTLLSTSYKKACVLQRQRKGSV SSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGLWFEETISPTKDKVAPPPPPPPPP LETSPRLKSPSKQNPSENGNILAGRKDPELFLSLASSILNFITTAMLKSRNNFIRNYLSV SLTEQHMATLASIIKDVDKDVKGSSDEVFSLALYHFNHTLVTSDLPSPALQSTLLQQLGV APFSEGPWPLYIHPQSLSVLSRLLLIWQHKASVQGEPDVPECMKVWERFLGTLKQHTIQG SVPGEDDLNVEHLQLLLLLFHNLSERGRRSVLTLVTQAITEVAQSKDSQLKAVPLNLARL CLVFDYLLRHYSKAPLYLFEQVQYNLLTPPSTGPSSVQEGGKRSGLPLYYFWIKVDEKII FYFHAFHPFLDSNNQPKFYCVLSPEASEDDITRLDSKVFPKLFNGAVKYDELYAWLISLL VAGSQFDTAKRQENKPVTPMEACSLQYYFLILWRILGVLPPSKAYMEQLKTGCIDPSESD ILHTLRWSSRLRVSTYVNWIKEHLVKQGMKADQAASLVEMTVAKCSTVKYDVELAEEYIA RQISTFSSVDPNAILPLDQLPSLQAIYTLDAVISKVQVSLDEHLSKVAIEADAHKSSEVT KNLLPATLQLADVYTAFTRSYLLLNIPDEGENKLTEAKLQGYAAVLSIGSTRCKANLLGH NIMQNLPSAVQTICETWNGIHTNEFPNIGSWRNAFANDTIPSESYISAIQAAHLGTLSCQ SLPLASSLKHILLSLVRLTGDLIVTEELNPSQVVRTLLPLLLESSTESVAEISSTSLERI LGPSESDAFLARIYERLVTGCYNIIANHSDPNSGLDESVLEECLQYLEKQLESSQVRKAM EEFFSFSGELVQIMMATANKSLSEKFCNRVLKFFTKLFQLTEKSPNPSLLCLCGSLAQLA CVEPSRLQSWLTRMTATPPKDSEQLEIVQENRQLLQVLTTHIVRDNSQVGEGVCTVLLST LIPMATDMLANGDGTGFPELMVIMATLASAGQGAGHLQLHRAAIDWLTRCKKYLTQKNVV EKVSTNISQGKHASMLECSCHIISYLADVMNALRQSSGQGTSALLMEGEEKAMEVDSDWV EELAVEEDDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKV CHKDHEISYAKYGSFFCDCGAKEDGSCQALVKRSPSSGMGSTLKESSAFQSELRMPDSAI RHQNASPSDKGKVTICDGKPGDEDKPKKSSVCKSIEGCQEELVSQVMGSSTAAVILEMLM FLMEAIQTNFQQASAVGSSSRAQQALNELHTQDKTVEMTDQLMVPTLGSQEGAFENVRMN YSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSTLLKQADSS KRKLTLTRLASAPVPFTVLSLTGNPCNEDYLAVCGLKDCHVLTFSSTGSVSDHLVLHPQL ATGNFIIKAIWLPGSQTELAIITADFVKIYDLSADALSPMYYFLLPSSKIRDATFLFNEE GKNIIVIMSSAGYMYTQLMDESSSAQHGPFYVTNVLEINHEDLKDSNGQVAGGGVSVYYS HVLQMLFFSYSQGKSFAATVSRSTTEVQRLFPINVKGSNGGSSKISPALCQWSEVMNHPG LVCCVQQTTGIPLVIMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTASNEQQRTTMILLCE DGSLRIYMANVDNTSYWLQPSLQPSCGISIMKPVRKRKAAATTTRTSSQVTFPVDFFEHN QQLTEVEFGGNDLLQVYNGQQIKHRLNSTGMYVANTKPGGFTVEAVNNNSSMVMTGMRVQ VGTQAIERAPSYVEVFGRTMQINLTRARWFDFPFTREEALQADKKLSIFIGASVDPAGVT MLDSIKIYGKTKEQFGWPEDPPEDFSSASVNNVCSPNLNQGNGTSDGDIATPTTTSGTVL ERLVVSSLEALESCFAVGSSSEKEKNKAAALELATLLLSMPTPAGVQQQTKGLLASLHTS RTAYHNHKDQSLLSNAVQCLNSCSREGRELDPDVFQRLVITARSIAIMRPNNLVHFTETK SLHHDSEMTEDGQKHVDGESCNFITQLMNNFWKLHALKPKNAFLAPACLPGLTHVEATVN ALVDIIHAYCTCELDYINVASKIYMQMLLCPDTSVSFACKQALIRVLRPRNKRRHVTLPS PPRSNTPMGDKDDDDDDDADDKMQSSVLTGGEEGRQESQEQSEVDHGDFEMVSESMVLET SDNVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGL QSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPAEHGGSVGSESG GSAIDSVAGEHSVSGRSSAYGDTTVEGHPAGPGSVSSSTGAISTTTAQQEGEGSEGEGET EGDIHTSNRLHMVRLMLLERLLQHLSQLHNVGGVQAIPYMQVILMLTSDLDGEDEKDKGA LDDLLAQLIAELCMHKKDVSKKNERSSINEVHLVIMRLLSVFMSRTKSGSKSSSESSSLI SNATATALLSLGAIDYCLHVLKSLLEFWKSQQGEEEPATTSQLLRPHTASSPPDMSPFFL RQYVKGHAADVFEAYSQLLTEMVLRLPYQIKKIADTNPRIPPPVFDHSWFYYLSEYLMIQ QTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRSIKKLLEEQGIFLRAGVVTATSG SALQYDTLINLMEHLKACAEIATQRTINWQKFCMKDDSVLYFLLQVSFLVDEGVSPVLLQ LLSCALCGSKVLASSSSSSFSGGGSSSAGQAGASQSSQSKSSSKKSKKEDREKDKEGDGV GSQEDQLCMALVSQLNKFADKETLIQFLRCFLLESNSSAVRWQAHCLALHIYRNSSKSQQ ELLLELTWAIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRAQNHIL TNHPNSNIYTTLSGLVEFDGFFLESDPCLVCNNPEVPFSNIKLSSIKVDTRYTTTQQVVK LIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQ TEVKIDLPLPIVASNLMIEFSDFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQC HKCRSINYDEKDPFGGAVTNINTLLDKADRVYHQLMGHRPQLESLLSKVNEAAPEKPQDD TGAGAGLGTSSANVNRYIQQLAQEYSGDCKTSFDELSKIIQKVLASRKELLEYDLQQREA ATKSSRSSSSHQPTITASQYRALSVLGCGHTSSNKCYGCASAVTGHCITLLRALATNPAL RQILVLQGLIRELFEYNLRRGTAAMREEVRQLVCLLTRDHPEATQQMNDLIIAKVSAALK GHWANPDLVSNLQYEMLLLTDSISKEGGCWELRLRCALSLFLMSVNIKTPVVVENITLMC LRILQKLIKPPAPTSKKNKDAAIESLTTVRPYSNEIHAQAQLWLKKDPKASYEAWKKCLP ARCQETVSKPQGKTELRRQYLLEKYVWKWKQFMRSKKGEGLFPRLLKLSHNNWLRQVLFT PATQAARQAACTIVEALTTIPSRKQQVLDLLTSYLDELSVAGECAVEYLGLYQKLIKPTH WKVYLAARGVLPYIGNLITKEIANLLSLEEATLSTDLQQGYALKSLTGLLSSFVEVESIK RHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIE TAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSN EPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLSVAEVYKKVWCPTNEG EPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDDEEVYKMAGVMAPCGGLECMLSRLSGI KDFKQGRHLLTVLLKLFSYCGKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGG ASIAEQVLSIMEIILDEANAEISEDKGNLLLTGDKDQLVMLLDQINTPFVRSNPSVLQGL LRIIPYLSFGELEKMRILVERFKPCCSFDKYDEEHSADDKVFLDCFCKIASGIKNNSNGH QLKDLILQKGITQSALDYMKKHIPNAKNLDADVWKKFLSRPALPFILRLLRGLATQHPPT QVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHSDVNLKIDAARRETRSEKKRMA MAMRQKALGTLGMTTNEKGQVVTKTSLLKQMEELIEEPGLTCCICREGYKFQPTKVLGIY TFTKRVALEDFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDTKLLFLRFATEQSFSV DTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFQEQPCEKWVESSYEVEGPH YFTILAMHILPPERWRSSRLYFLRRLLVNAHARKVSAVCTNKLTDKAPKEYAVYRSPLLF WGLVDLVYDMFRKVPTSNTEGGWSFSLAEYVRHNDMPIYEASERVLRAFQDELMPAESLS EFCDVVGLLAEIADPDLFLQDLLNSLP NT seq 15384 nt NT seq  +upstreamnt  +downstreamnt atggcgtcgagtggaggagatggggaacacgaatggacagcggcagtacggccgctttta tcagcttcgtacaccgcttttgaaacgaaggagctacctcagcttattgggtctataatc aacagtgaatcagacatccttcaccatgacaaacagtatgagcctttctactcatcattc gtggcactctctgcacactacatcaccacagtatgtgggcaaataccgagaaatcagctg ctgtcggttgctgcagcgtgcaaagtattgattgaattctcactgctgcgcttggagaac ccagatgaggcatgtgcggtatcacagaaacacctgattcttctaataaaaggtctttgc attggctgcagcagactagatcgcacagaaatcattactttcactgctatgatgaaatct gccaagttgcctcaaaccgtcaagaccctttcagatgtggaagatcagaaggagttgccc agtgctgtgaacccagaacttcgacaaaaagaagtacaaatgaacttctttaatcaactg acttcagtttttaaccctgaccttaccaccatcttggcctccccatcagcagcacacatg caggcagagagtgattgcgatgaccaaaccacagatcaagccattcaggccaaaatgaaa aatgcctttgtctctcagaatgtgtcaagcttacaggaacttggtgggtctgagaagttg cttcgtgtgtgcctcaacctgccctactttctgcgctacatcaaccgtttccaggatgct gtatcagccaactctttcttcatcatgcctgctacagtggctgatgccactgctgtccgc aatggatttcattcactggtgatagacgtaaccatggctttggacacactttccctgcct gtactggagcccttgacgccagggagattactggatatgaccgtgctggctttgagctgt ctctatgctggtgtgagtgttgccacttgcatggccattctgcaggtaggtagcggcttg cagcttcgctcaacctccactgggactaaagaggaggactatgaaaatgacgcagccaca attgtccagaaatgtctggagatctatgaaatgattggacaagccatcagcaactcccgc agagctggaggagagcattatcagaacttccagctgcttggagcctggtgccttttaaac agcctgtacctgattcttaacctgagccccactgccctggcggataaagggaaagagaag gatcccctggctgccctgcgtgtccgtgatattgctgctcgcacaaaggatggtgcagga tcacctaaacttggtcctggcaaaggacaccaagggtttggtgttttgtcagttatcctg gcaaaccacgccatcaaacttttgacttcgcttttccaggatctgcaagttgaggctctg caccgaggttgggcgagtgatgggcctccagctgagctcaacatcatggcacagagcact tccatccagagggtccaaaggctcatcgactccgtgcccctgaccaatctactcttcacc cttctctccacttcctacaaaaaggcttgtgttctccaacgccagaggaagggctccgtc agcagtgatgccagcgcttccacagattcaaacacctactatgaggatgatttcagcagt acagaggaggatagcagtcaagatgatgacagtgaacccatcttggggctttggtttgaa gagacaatttcgcccaccaaagacaaagtcgctcccccaccccctccaccccccccacct ctggagacctctcccagactgaagagccccagcaagcagaatccaagtgagaatggcaac attttagctggccgcaaagacccagaactgttcctcagtttagcttccagcattctgaac ttcatcaccaccgcaatgctcaagtccaggaacaacttcatccgcaactacctgagcgtg tctcttacagagcagcacatggctacactagccagcatcatcaaagatgtggacaaagat gtcaaaggctcctcagatgaagtgttttctttagctctatatcacttcaaccacaccctg gtaacatcagatcttccatccccggccctgcagagcacccttcttcagcagttaggtgtt gcgcccttttcagagggtccctggcctctgtacattcaccctcagtcactatccgtgctc tccagacttctactcatatggcagcacaaagcaagtgtgcaaggggagccagatgtaccg gagtgtatgaaggtctgggaaagatttttgggaactttgaagcagcacactatccagggt tctgtgcctggagaagacgaccttaatgtagagcacctccagctcctgctgctccttttc cacaatctgtcagaacgtggtcggcggtcagtcctgaccctggtcacccaagccatcact gaagtggctcagagcaaagattctcagctgaaggcagtgcccctcaacctggcccgcctg tgtctggtttttgactacctgctgcgccactactccaaggcgcccttgtacctttttgaa caggtgcagtataacctcctgaccccaccatccaccgggccgagttctgttcaggaaggt ggcaaacgcagcgggctcccactttactatttttggattaaagtagatgagaaaataata ttctattttcatgcatttcatcctttcttagattcaaataatcagcccaaattctactgt gttctgtcccctgaggcatctgaagatgatatcaccagactggacagcaaggtctttcca aagctgttcaatggagcagttaaatatgatgaactgtatgcgtggctcatctcactgctg gtggcaggctctcagtttgacacagcaaaaagacaggagaacaagccagtcactcctatg gaggcatgctcccttcagtactacttcctgatactgtggaggatcctgggtgttttacca ccctcaaaagcctacatggagcagctaaagactggctgcatcgatcccagtgagagtgac atcctgcacaccctgcgatggtcctcacgtctccgggtctctacctacgtaaattggatc aaggaacacttggtgaagcagggaatgaaagcagaccaagcagcctctctggttgagatg acggttgctaagtgcagcaccgttaaatacgacgtggagctagcagaggagtacattgcc agacagatttccaccttctccagtgtagacccgaacgccatccttccacttgatcagtta ccctctctacaagccatctatacactggatgcagtcatctctaaagtgcaggtttccctc gatgagcatttgtccaaggttgccattgaggcagacgcccacaagtcatctgaggtcaca aagaacctactgcctgccacactacagcttgctgatgtttacacagcatttacaaggtct tacttactactgaacatcccagacgaaggggagaacaagcttacagaggccaagctccaa ggttatgctgcagttctgtctattggctccacccgctgcaaagccaacctgctgggtcat aatattatgcagaacctaccatcggctgtacagacaatatgtgagacttggaacggcatc cacaccaatgaattccccaacattggctcatggcgaaatgcatttgccaatgataccatt ccatcagagagctacatcagtgccatccaagcagctcacctgggcacattgagttgtcag tccttgcctctggcctcttctcttaaacacatcctgctctctttggttcgcctcactggc gacctcattgtcacagaggagctgaatccttcacaggttgtgcgcactttgctgcccctc ctcctggagagcagcacagagagtgtagctgagatcagcagcacctcactggagcgcatc cttggcccatcagagtcagacgccttcctagcccgcatctacgagcgtttggtcaccggg tgttacaacatcattgccaatcactcagacccaaacagtggtttggatgagtctgtcctt gaggaatgccttcagtaccttgaaaagcagcttgagagcagtcaagtccgtaaggccatg gaagagttcttttcattcagtggtgagctcgtccagattatgatggcaacagccaacaaa agtttatcagaaaagttctgcaacagggtgctgaaattcttcaccaagcttttccagctc acggagaagagcccaaaccccagcctgttgtgtctgtgtggctctctggcccagctggcc tgtgtggagccatctcgtctgcagtcctggctgactcgaatgacggccaccccgccaaag gactctgagcagctggaaatagtgcaagaaaaccgacagctcctgcaggtgctaaccact catattgtgcgtgacaacagccaggtgggcgaaggagtgtgcactgtcctcctcagcaca ctcattcccatggcaacagacatgctggccaatggtgatggaacaggctttcctgagctc atggtcatcatggcaacacttgccagcgcaggacagggggccggtcacctgcaactgcac agggcagctatcgactggctgaccagatgcaaaaagtatttaacacagaagaatgtcgtg gaaaaagtgagcacaaacatatcccaaggaaagcacgccagcatgctggaatgctcgtgc cacatcatctcctatctggctgatgtgatgaatgccttgcggcaaagcagtggccaaggc acctcagcactgctgatggagggagaagagaaggccatggaagtggactcggactgggtg gaggaacttgcagtagaggaggatgattcccaagcagaggactctgatgaggactccctt tgcaacaaactctgcaccttcactattactcagaaggagttcatgaaccagcactggtac cactgtcacacctgtaagatggtggatggggtaggtgtgtgcacagtgtgcgccaaggtc tgtcacaaagaccatgagatctcctatgccaaatatggctctttcttctgtgactgcggt gccaaagaggatggcagctgccaggccttggtcaaacgcagccccagcagcggcatgggc tccaccctgaaagagtcttctgccttccagagtgagttgcgtatgcccgacagtgctatt cgccaccagaatgcctcaccttccgacaagggcaaggtcaccatctgtgatggcaaacct ggtgatgaagacaaacctaagaagagcagtgtgtgcaagagcattgagggctgccaggaa gagctagtatcacaagtgatgggatcatccactgcagcagtcatactagagatgctcatg tttctcatggaagccatccagaccaacttccagcaggcatcagcagtgggaagcagcagc cgggctcagcaagcactcaatgaactgcatactcaggacaaaactgtggagatgactgac cagttaatggtgcccacactcggctctcaggaaggggcttttgagaatgtgaggatgaac tacagtggtgaccagggacaaactatacgccaactcattagtgcgcatgtcttgcgtcgt gttgccatgtgtgtcctgtcttcaccccacggccgccgccagcaccttgcagtcagccat gaaaaggggaagataaccgttctgcagctgtccactctcctgaaacaggctgactcgagc aagagaaagctaacactgacccgactggcctctgctccagtccctttcactgtcctcagt ctcacaggcaacccttgtaatgaggattacctggctgtgtgcggcctcaaggattgccat gtactaactttcagcagcacaggctctgtgtcagaccatttggtgttgcatccacaacta gcaactggcaactttatcatcaaagccatttggttaccaggctcacagactgaacttgct atcatcactgctgactttgtcaagatttatgacttatcagcagatgccctgagtcctatg tactacttcctgctcccaagttccaagatccgtgatgctaccttcctgttcaatgaagag ggtaaaaacatcatcgtcatcatgtcttcagcaggttacatgtacacccagctcatggat gaatccagcagtgcccaacatggccctttctatgtcacaaatgtattggagataaaccac gaagacttgaaggatagcaacgggcaggtagctggcggtggtgtgtctgtctattactcc catgtgcttcagatgcttttcttcagctacagccagggaaagtcttttgctgccacagtg agccgcagcaccactgaagtgcaaaggctcttccccatcaacgtcaaaggctcgaatggc ggcagcagtaagatttcgcctgctctgtgccaatggtctgaggtcatgaaccacccaggc ctggtgtgctgcgtgcagcagacaacaggcataccgcttgtcatcatggtcaagccagac accttcctcatccaagagattaaaactctgccagccaaagccaagattcaagatatggta gctatccgacacacggccagtaatgagcaacagcgtacaaccatgattcttctctgtgaa gacggaagcctgcgaatctacatggccaatgttgacaacacctcttactggctccagcca tcactgcagcccagctgtggcatcagtatcatgaagccggtccgcaagcgtaaagctgct gctactactacccggacctccagtcaggtgacgtttccagtggatttctttgaacacaac cagcagctgacagaggtggagtttggtggcaatgacttgttgcaggtctacaatggacag cagattaaacacaggcttaactccactgggatgtatgtggccaacacaaagcctggggga ttcactgtggaagcagtcaacaacaacagttcaatggtgatgacgggtatgcgggtgcag gtgggcactcaagccattgagagggctccttcctacgtggaggtctttggacgcaccatg cagataaacctgacgagagcccgctggtttgactttcccttcaccagagaggaggccctg caggcggacaagaagctgtctatctttattggagcatctgttgacccagctggagtcacc atgcttgattcaatcaagatctacggtaaaaccaaggagcagtttggctggcctgaggat ccaccagaggacttctcctctgcctcggttaacaatgtctgcagtcccaacctcaaccag ggcaatggcacctctgatggagacatagccactccaaccaccaccagcggcactgtgcta gaaaggttggtagtcagctcccttgaggctttggaaagctgctttgcagtaggttcatcc agtgaaaaggagaagaataaggctgcagcactggagttggccactctactcctgtccatg ccgaccccggcaggtgtgcagcagcagaccaagggacttcttgccagcctgcacaccagt cgaactgcctaccacaaccacaaggaccagtccttgctgagtaacgcagtgcagtgtctg aatagttgcagccgtgaggggagggagctcgaccctgatgttttccagaggctcgtgatc actgcccgctccattgcaatcatgagacccaacaacttggtgcatttcacagaaacaaag tcattacaccatgactctgaaatgacagaggatgggcaaaaacatgtggatggtgaaagt tgtaatttcatcacgcagctgatgaataacttctggaagctccatgccctaaaaccaaag aacgcctttcttgctcctgcttgcctgcctggcctaactcatgtggaagcaacagtaaat gccttggtggacatcatccatgcctactgcacatgtgaactggattacatcaatgttgcc tccaaaatctatatgcaaatgttactgtgcccagacacatctgtgagctttgcttgtaag caggctctaatcagagtgcttcgaccaagaaacaaacggcgacatgtgacccttccatct cccccacgctccaacacacctatgggagacaaggatgatgatgacgacgacgatgcagat gacaaaatgcagtcttcagtgctgactggaggagaagagggtagacaggagagtcaggag cagagtgaagtggaccatggcgactttgagatggtgtcagagtccatggtcctggagaca tcagataatgtcaacaatggaaatccatctcctctggaggctctgctggctggagcggag ggtttcccccccatgctggacatccctcctgatgcagatgatgaaactatggtagagctg gccatcgccctcagccttcagcaggatcaacaaggcagtagcagcagtgccctcggtctt cagagccttggtctgtctggccaggccccaagctcctcttcactggatgctggcaccctt tcggacaccaccgcatcagccccagcatcagatgatgagggcagcacagctgccactgat ggctccacgctgcggacctccccagctgagcatggcggcagtgtgggctcagagagtgga ggctctgcaatcgactctgtagcaggggagcacagtgtgtctggacgcagtagtgcatat ggggacacaacagtggaaggccaccctgcgggtccaggcagtgtgagctccagcactggg gctatcagtaccaccacagcccagcaggaaggcgaaggctcagagggagaaggagagacc gagggagacatccacacaagcaacaggctacacatggttcgtcttatgctactggagcgc ttgcttcagcatctttctcagctccacaacgtaggtggagtccaagccatcccttacatg caggttatcctcatgttgacttctgatctggatggcgaggatgaaaaggataagggtgcc ttggatgacctactagcacagcttattgctgagctttgcatgcacaagaaggacgtttcc aagaagaatgagcgtagctccatcaatgaagttcacctagtcatcatgagactgctcagc gtcttcatgtctcgaaccaagtctggctccaaatcctcttctgagtcatcctcgcttatt tcgaacgccacagcgactgccttgctcagcctgggtgctattgactactgtctccacgtg ctcaaatcgctcttggagttctggaagagccaacagggtgaagaagagcctgcgaccacc agccagctcctccgcccacacacagcctcctctccgccagacatgagccctttcttcctg cgccaatatgtcaagggacatgctgctgatgtgtttgaagcctactcccagctattgact gaaatggtgcttcggctgccgtatcagatcaagaagattgctgacaccaacccacgtatc ccacctcctgtctttgaccattcctggttctactatctgtctgaatatctcatgattcaa cagacaccattcgtcaggaggcaagtcagaaagctgttgctgtttatctgcggctcaaag gaaaaatatcgtcagctgcgcgatctgcacactcttgactcccatgttcgcagcatcaag aagctcctggaggagcagggcatcttcctccgggctggtgtggtcacagccacgtctggg tcagctctgcagtatgacacactcatcaatctaatggaacatctaaaagcttgtgcagaa attgccactcagaggacgatcaactggcagaagttctgcatgaaggacgactctgtgttg tacttcctgctccaggtcagcttcctagtggatgagggtgtttccccagtacttttgcaa ctgctctcctgtgccctttgtggcagtaaggtgctggccagctcctcctcttcatcattc tcaggaggaggatcgagtagtgctggacaggcaggagcttctcagtcttctcagagcaag tcctccagtaaaaagagcaaaaaggaggacagggaaaaagacaaagagggtgatggagtt ggcagccaggaggatcagctgtgtatggctctggtcagtcagcttaacaagtttgcagac aaggagacactgatccagttcttgcgttgcttcctgctggagtcaaactcatctgctgtg cgctggcaagcccactgcttggcgcttcatatctacaggaactccagtaaatctcagcag gagctgctactggaactgacttgggccatctggcctgagctgcctgcatatggccgcaaa gctgcccagtttgttgacctgcttggatacttctcactcaaaacccctcagacagaaaaa aagctaaaggagtattcccagaaagctgtggaaatcctgagggcacagaaccatatcctg acaaatcaccctaactccaatatctacaccactctgtctggattagtggagtttgatgga ttttttctggagagtgacccctgcttggtgtgcaacaatccagaagtacccttttcaaat ataaaactgtcatctatcaaagtggacacccgctacaccaccacacagcaggttgtcaag cttattggcagccacaccatcagcaaagtcacagttaaaatcggtgacctcaaacgcacc aaaatggtccgcaccatcaacctctactacaacaacaggactgtgcaggctatcgtggag ctgaagaataagcccgctcgttggcacaaagctaagaaagttcagctgaccccaggacaa acagaggtgaagattgaccttcctttacccattgtcgcatccaacctgatgatcgagttc tcagatttttatgagaactaccaggcctccaccgaaaccctccagtgtccacgctgcagt gcctctgtgccagcaaaccctggagtgtgtggcaactgcggtgagaacgtgtatcagtgc cacaagtgcaggtctatcaactacgatgaaaaagaccccttcgggggggctgtgaccaac ataaataccctgctggacaaagctgaccgggtttaccatcagctgatgggccaccggccc cagttggagagcctcctgtctaaagtcaatgaggcagcaccagagaaaccacaggatgac actggagcaggtgcaggacttggtacctcctctgctaatgtgaacagatacattcagcag ctggctcaagagtacagcggagattgcaagacgtcatttgatgaactttccaagattata cagaaagtgcttgcatctcgtaaagagctcctggagtatgatctacagcagagagaggct gccaccaagtcatcccgcagcagcagcagccaccagcccaccatcaccgccagtcagtac cgtgccctctctgtgctgggctgcggccacacctcctcaaacaagtgctatggctgtgcc tcagctgtcacgggtcactgcatcacactgcttcgcgcactggccacaaacccagccctc cggcagatcctggtcctccagggtctcatccgtgaactgtttgagtataacttgcggcga ggtacagcagccatgagggaggaggtgcgccagttggtctgtctcctcaccagagatcat ccagaggccacccaacagatgaatgacctcatcattgccaaggtgtctgctgccctcaaa ggccactgggccaatcctgacctggtcagtaatctgcagtatgaaatgctgctgctgaca gactccatttcaaaagagggaggatgctgggagttacggttgcgttgtgccctcagtctg ttcctcatgtcggtgaatataaagacgcctgtagtggtggagaacattactctcatgtgc ctgagaatcctgcaaaagttgatcaagccccctgctcccacaagcaagaagaacaaggat gctgctattgaatccctaaccacagtcaggccctacagtaatgaaatccatgcccaggcc caactctggctcaagaaggaccccaaagcatcttatgaggcctggaaaaagtgtctccca gcaagatgccaggaaactgtgtcaaagcctcaggggaagactgagttgcgaaggcagtac ctgttggagaagtatgtttggaagtggaagcagttcatgaggtccaaaaaaggtgaaggc ctcttccctcgtctgctcaaactgagccacaacaactggctgcgacaggtccttttcaca cctgccactcaggcagccagacaggcagcttgcactattgtggaagcccttaccacaatc cccagccgcaagcaacaagtcctggacctgctcacgagctatctggatgagttgagtgta gctggagagtgtgcggtggagtacctgggtctgtaccagaagttgatcaagccaacacac tggaaggtttacttggcagcccgtggagtcctgccctacatcggtaacctgatcaccaag gaaatcgccaacctgctgtctctggaggaggcgacactgagcacagacttacagcaaggc tatgccctcaagagcttgactggattgctttcttctttcgtcgaggtggagtccattaag cggcatttcaaaagtaggttggtcggcacagtgctcaacggctacctgtgtctgaggaaa ctggtggtgcagcgcactaagctcatcgatgagactcaggacatgctgctagagatgctg gaggacatgacaacaggtactgagtctgaaaccaaagcattcatggcagtgtgcatagag acagcaaagcggtacaacctggacgactacaggacacccgtgttcatttttgagagactg tgcagcatcatctatcctgaggagaatgaggtgacagagttctttgtgacactggaaaag gatcctcagcaggaggacttcctgcagggtcgcatgccaggaaacccctacagcagcaac gagcctggcattggccctctaatgagggacatcaagaacaaaatctgccaagactgcgac ctggtggcgcttcttgaagacgacagtggcatggagcttctggttaacaacaaaatcatt agcttggatctgtcggtggcagaggtctataagaaggtctggtgccctacaaatgagggt gagccaatgagaatcatctatcgaatgagaggtctgctgggagatgccactgaggagttc atagagtcactggactcaaccacagatgaggaggaggatgatgaggaggtgtacaagatg gcaggagtcatggcaccgtgtggaggactggagtgtatgctcagccggctttctggaatc aaagattttaaacaaggaagacatctgctcactgttttgctgaagttgttcagttattgt gggaaggtgaagatcaacaggcagcagctggtcaaaccagagatgaacacactcaacgtc atgctgggaactctaaacctggctttagtggcagaacaggagagcaaggacagtggtgga gcctccatagcggagcaagttctgagcataatggagatcattctggacgaagccaacgct gagatttcagaggacaagggtaacctgctgctgacaggagacaaagatcagctggtcatg ttgttagaccagatcaacaccccgtttgtgcgctccaaccccagcgtgctgcagggtctg ctgcgcatcatcccatacctgtccttcggtgaactggagaagatgaggatcttggtggaa cgcttcaaaccatgttgcagctttgacaagtacgacgaggagcacagtgcagatgacaaa gtgtttttggattgcttctgtaaaatcgcttctggaatcaaaaataacagcaatggccat cagctgaaagatcttattctccagaaaggaatcacacagagtgcactggactacatgaag aaacatatcccgaatgccaaaaatctggatgctgatgtctggaagaagttcctctccaga ccagctctacccttcattctcagattgctccgtggtttggctacccaacatccccccaca caggtgctgataggcacagattcaataaccaacttgcacaagctggagcaggtatccagt gacgaaggcatcggcacgctggcggaaaaccttctggaggcgctgagggagcacagtgat gtcaacctgaagattgatgccgcccgcagagagacccgatctgaaaagaaacggatggcg atggccatgagacagaaggccctgggaacactgggcatgacgaccaatgagaaaggtcag gtggtgaccaagacctcactgttaaagcaaatggaggaactgatagaggagccaggcttg acctgctgtatctgtagagaaggttacaagttccagccaaccaaagtcctgggtatttac actttcacaaagcgtgtggccttggaggatttcgaaaacaagcctcggaagcagcagggc tacagcaccgtgtcgcactttaacatagtccattatgactgccatctggcagctgtcagg ctggctcgtgggcgagaggagtgggagagtgctgctctccagaatgccaacaccaagtgt aatgggctgcttcctgtttgggggccacatgtgccagaatcagcctttgctacatgctta gccaggcacaacacatatctgcaggagtgcacgggccagcgggagccaacgtaccaactg aacatccatgacaccaaactgctgttcctccgctttgctaccgaacaatcattcagtgtg gacacaggcggaggagggcgagagagcaacatccacctcatcccctacatcatccacact gtgctctacgtcctcaacactacaagggctacgtcccgggaggagaagaacctgcagagt ttccaggagcagccgtgtgagaaatgggtggagagctcatacgaggttgaagggccgcac tatttcaccatcttggccatgcacatcttgccgcctgaacgctggaggagttcacgttta tacttcctacgaagactcttggtcaacgcacacgcccgcaaggtctcagcagtctgcacc aacaaactcacagataaagcaccaaaggaatatgcagtctatcgctcgcctcttctcttc tggggcctggtggatctcgtctacgacatgttcaggaaagtacccaccagcaacacagag gggggctggtccttctcgctggcagaatatgtccgtcacaacgacatgcccatctacgag gcctcagagcgcgtgctccgggccttccaggatgagctcatgcccgccgagtccttgtca gaattctgtgatgttgtaggtctcctcgctgaaattgcagacccagacctcttcctgcag gatttgttgaactctttgccctaa

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