Perca flavescens (yellow perch): 114547290 Help Entry 114547290         CDS       T07494                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism pflv  Perca flavescens (yellow perch) Pathway pflv04020   Calcium signaling pathway pflv04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:pflv00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     114547290    04020 Calcium signaling pathway     114547290  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pflv04040]     114547290 Ion channels [BR:pflv04040]  Voltage-gated cation channels   Ryanodine receptor    114547290 SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Motif Other DBs NCBI-GeneID:  114547290 NCBI-ProteinID:  XP_028422374 LinkDB All DBs Position 20:13603645..13716580 Genome browser AA seq 4878 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICTFVLEQSLSVRALQEMLAKSGQNSEGAAQSGGHKTLLYGHAILLRHSFSSMYLAC LKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSISNGNIQVDASFMQTLWNVHPICSGSNIEEGYLLGGHVMRLFHGHDEVVAIPGSDQS EEQQRIVNYETGKAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLALTEDRG LVLQDRERSDTIATAFCFRASKEKLEQSPKRDIEGMGVAEIKYGDSLCFIMHMATGLWLS YQAPDVKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTLLFNRFIRDL DCLGVKNRVLVSLPVEEVLQTLNDLITYFQLPDAELEHEERQIKLRSLKNRQNLFKQEGM LTLVSNCIDRLNLYNSAAHFGECAGSEAGAAWKDILNLLYELLAALIRGNRNNCTQFSNN LDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRTNQNLICDHLLPKRDLLLQTQLVNDVQSMRPNIFLGVSEGSAQYKKWY YELMIDQVDHFVTSEPTHLRVGWANAKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRIPRAVASMNQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSF SAGVKVRFLLGGRHGDFKFLPPSSYVPCYEALLPKEKMKVEPVKEYKRDANGVRDLLGTT QFMSQASFIPTPVETSQIVMPPHLEKVRDKLAENIHELWGMNKIELGWSYGKIRDDNKRQ HPCLVDFSKLPDTEKNYNLQMSTETLKTLLALGCRVVQVNPNAEGSLKKIKLPKNYMMSN GYKPTPLDLSDIKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKRNPRLVP YVLLDERTKKSNRDSLREAIRTLIGYGYNIEPSDQEGGQVVERLSIDRVRFFRVERTYAV KTGKWYFEFEAVTGGDMRVGWARPGCKPDVELGTDELAFVFDGYRGHCLNMGSRLFGRCW HAGDVVGCMINMEDKSMIFTLNGEILITTKGSELCFTDFETEDGFIPVCSLGLAQVGRMN LGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKDHNHIAVTRIDGT IDSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFHSFFKSSSVVDMNGVHEEDTLKVKHR YPLRSVRHSDESRRVDYSSITTYYHSVRVFAGQDPAGVWVGWVTPDYHYYSNNFSLSKNR SVTVTLGDERGRVHESVKRSNCYIVWGGDVTSATHTSSRSNVDLEIGCLIDLATGLVTFT VSGKEITTSYQVEPNTKLFPAVFVRPTSPNLFQFELSKIKNAMPLSSAIFKSEHKNPVPQ CPPRLYVQTISAVLWSRMPNTFLKVETARVNERHGWVVQCVEPLQMLAVHIPEENRCVDI MELSEQEDMRRFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREG FYNVLISTHLETAKEARLMMKDEFIIPVTAETRSIRLFSDASKKHLPPGVGLSTSLKPRL NFAPPCFISTKREQHLYSPQIPLGALKEKSISMLTEAVQGGGHHIRDPVGGGVEYQFVPI LKLISTLLTMGVLGSEDVHKILLLIDPNVFRQTREEGATGATDKEGLTGAEEKAVEAGEE EVAKEAKQPMKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQYNQ KFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLTFSVGEDCPCPTDIQEELYDFHN QLQLHCGIPMEEDEYEQATSIKGRLLMLVNKIKGQSHKAEEPTEKEQAAPSNLKELISQT MVSWAQECHVLDSELVRKMFSLLRRQYDSIGELLRAMRKTYTISAASIQDTINLLAALGQ IRSLLSVRMGKEEEKLMIDGLADIMNNKVFYQHPNLMRILGMHETVMEVMVNVLGGHKSQ EIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAS SVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPILLAKGYPDIGWNPIEGERYLSFLRFA VFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALDLPGSV HGVSSDVSADGDDEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILR SLVPTEDLVGIISIPLKMPIPNKDGSVTEPDMSACFCPDHKSPMVLFLDRVYGIEDQSFL LHLLEVGFLPDLRAATSLDTEGLCTTETALAMNRFIGSAMLPLLTRCAPLFAGTEHYATL IDSTLHTIYRLSKGRSLTKAQRDAIEECLLAVCKHLRPSMLQQLLHRLVFDVPLLTDYCK MPLRLLTNHYEQNWKYYCLPLGWGSYGTASEDELLLTKKIFWGVFDSLSQRKYDAELFKM AMPCLSAIAGALPPDYVDASISTTVEKPVSVDAQGNFDPKPISTANIALPEKLEHFANKY AEHSHEKWSAEKVLLGWKYGDCVDEKAKIHPQLRIYKALTEKEKEIYRWPIRESMKSMLA MGWSIDRTKDGESMSQQRENEKMRKISQASQANGFNPSPIDTSNVVLSRELQGMVEVLAE NYHNIWAKKKKCDLGSRGGGTHPLLVPYDTLTAKEKARDREKAQDLFRFLQINGYSITRG LKDLEQDSSSMEKRFAYKFLKKLLKYVDSAQEFIAHLEAMAASGKTDRSPHEQEIKFFAK VLLPLIDQYFKNHSLYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFGSD STTIVSCLHILAHTLDTRTVMKSGSELVRVGLRTFFENAAEDLEKTFENLKLGKFTHSRS QMKGVSQNINYTTVALLPILTALFEHITQHHFGVDLLLDDVQVSCYRILTSLYALGTGKN IYVERQLPALGQCLATLAGAMPVAFLEPILNTYNPCSVFNTKSARERANLGIADSVKEMC PGMPRLDGLMKDINDMAESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENQPASGVSVC CTTVTSENLSLILGNILKILNNNLGIDEASWMKRIAVYVQPIISKARADLLKSHFLPTLE KLKKKTVKVVSEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRW LKEPDVDSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDNKTKMSKSGG QDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYLLRDTDEE VKDHIRQNLHLREKSEDPAVRWQLNLYKNITMRSEGPPDPERVVDRIQRISAAVFNLEQV EQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLAYQRIWIETEEYSF EEKLVQDLAKTQPKMEEEEEEEVRKQPDPLHQLILHFSHNALTECSSLEEDPLYIAYADM MAKSCDEGEEEEDVEGKEKTFEEKEMEKQKMLYQQARLHDRGAAEMVLQMISASKGRLGA MVTFTLKLGISVLNGGNILVQQKMLDYLKEKRDVGFFKSLSGLMMSCSVLDLNAFERQNK AEGLGMVTEEGSSSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIIS TVDYLLRLQESISDFYWYYSGKDIIDEAGQRNFSQALAVAKQVFNSLTEYIQGPCIGNQQ SLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVMMLSLLEGNVVNG TIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKEYDPERKGVISKKDFQKSME NQKQYSQSEIEFLLSCAEADENDMFNYEQFVERFHEPAKDIGFNVAVLLTNLSEHMPHDA RLSTFLDLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFI FDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDPAERPEEDEVDNQSVVEKQQQEE EEEESVMLESSSAFTIACVSMKKSLCHFRQLLTLKSMRRQYRKFRKMSVREMVRGFFSFF WMIITGLFHFVYSLVWGFFHILWTTMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVL EMEKMEASEASALAEMGQMAQGDAAEADLMAELLNIQPKKEGKHGAEPGLGDVSEVVVGD APSIASAVKQKKAQLAAKKRAVNGDYKSDSEKGDSEDGEKKDHDKAKDEGPPEPPVEKKA PKKRIGHKKELPEVFMASFFAGLEIYQTKMLNYLARNFYNLRFLALFVAFAINFILLFYK VAGDYSDDEDPWDGRGRTREEEEEDEAALEYFVLQESTGYMAPTLRCLAILHTIISFLCV VGYYYLKVPLVVFKREKEIARKLEFAGLYITEQPSDDDIKGQWDRLVINTLSFPNNYWDK FVKRKVIKKYGDLYGAERIAELLGMDKSALDFNPTEETVVKEASLVSWLSSIDTKYHVWK LGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVL TVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGD EIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCF ICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCW DFFPAGDCFRKQYEDQLG NT seq 14637 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggagaggatgagattcagttcctcagaactgatgatgaagtg gtgctccagtgcgtggcctgcatccagaaggagaatcgcaagttctgcctggctgctgag gggctgggcaatcggctgtgttacctggagcccacatctgaggcaaagtatgttcctcca gacctgtgcatctgtacctttgtgctggaacagtctctgtcagtacgggccctacaggag atgctggctaagagcggacagaacagtgaaggggcagcgcagagtggcggacacaagact cttctgtatggacacgccatcctcctgcggcattccttcagctctatgtatctggcctgt ttgaagacatcaagatcacagacagataagctgtccttcgatgtcggtctgcaggaggat tcaacaggtgaggcctgttggtggacgatccaccctgcctccaaacagagatctgaagga gagaaagtgcggatcggtgatgacctcatcctcgtcagtgtgtcctcagagcgatacctt cacttatccatctccaatggcaacattcaggtggatgcttctttcatgcaaaccctgtgg aacgtccatcccatctgctccggtagcaacatagaagaaggctacctgttgggtggtcat gtgatgcggctgttccatggacatgacgaggtcgtggccatcccaggatcagaccagagt gaagagcagcagaggatagtcaactatgagacgggtaaagccggtgccaaggccaggtcc ttgtggaggctggagccgctccgcatcagctggagtgggagccacatccgctggggccag cccttccgactgcgccacctgaccaccggtcactacttggccctgactgaggataggggt ttggtgctgcaggaccgggagaggtcagacaccatcgccactgccttctgcttcagagcc tctaaggagaagctggagcagagccccaagcgggacatcgagggcatgggggtggcagag attaaatacggagactctctctgcttcatcatgcacatggccacgggactctggctctct taccaggcacctgatgtcaaatccgcccgtctgggtcccctcaagagacgagcgtgccta cattctgaaggtcacatggatgacgggttgaccttgcagcgctgtcaacacgaggagtcc cgcgctgcacgaatcatccgcaacaccacactacttttcaaccgattcatcagagacctg gattgtctgggtgttaagaatagggtactggtctcgctacctgttgaggaggtgctccaa accctcaatgacctcatcacatatttccagctccctgatgctgagctggagcatgaagag aggcagatcaagctgcgctcgctcaagaaccggcagaaccttttcaaacaggaaggcatg ctgactctggtgtccaactgtatcgatcgtctcaacctctacaacagtgctgcccacttt ggtgagtgtgcggggtcggaggccggagcagcctggaaagacattctaaacctgctgtat gagctgctggctgcgttaataagagggaacagaaacaactgcacccagttctccaacaac ttggactggctggttagcaagctggagagactggagtcttcttcaggcatcctggaagtt ctgcactgcattctaattgagagccccgaggccctcaacattatccagagaggacacatc aagtccatcatatcgctgctctacaagcacggacgcaaccacaagattctggatgtgctg tgctcgctgtgtgtgtgtaacggcgtagctgtgcgaaccaatcagaacctaatctgtgat cacttgctgcccaagagagatctcctgctgcaaacccagctggtcaatgatgtccagagt atgagaccgaatatcttcctgggggtgagcgagggctcagctcagtataagaagtggtac tacgagctgatgattgaccaggtggatcactttgtgaccagtgagcccacccacctgaga gtgggctgggccaatgctaaaggctacgctccctaccctggaggaggagagggatgggga ggcaatggggttggagatgacctctactcgtatggttttgatggactccacctctggtca ggtcgtatcccgcgggcagttgcgtctatgaaccagcacatcctgacctcagaggatgtg gtgagctgttgtctggacctgggagctcccagcatctctttcaggatcaacggacagccc gttcaaggcatgttcgaaaatttcaacactgatgggctcttcttccctgtcgtcagcttc tctgcaggggtcaaggtgcgtttcctgttgggtggccgacatggcgactttaagttcctg cctccgtcaagttacgttccatgttacgaagctctgctgccaaaagagaagatgaaggtg gagccagtgaaagagtacaagagggatgcgaatggagtccgagatctgcttggcaccaca cagttcatgtcacaggcctccttcatccccacacctgttgaaactagccagattgttatg ccgcctcatttagagaaagttcgagacaagcttgctgagaacatccacgaactgtggggc atgaataaaattgagctgggttggtcgtatggcaagataagggatgataataagcggcag cacccgtgcctggtggatttctccaagctgccagatactgaaaagaactacaatctgcag atgtcaacagaaactctgaagactctgctggcattgggctgtcgtgtagttcaggtcaat ccaaatgctgagggctccctcaaaaagataaaactccctaagaactacatgatgtccaat ggttataagccaactcctctggatctgtctgacataaaactgactccaggtcaggagctg ctggtggacaaactggcagaaaatgcacacaatgtgtgggccaaggaccgcatcaaacag ggatggacctatggtattcagcaggatctaaagagtaagcgtaaccctcgcctggttccc tatgttctgctggatgagcgcaccaagaagtcaaacagggacagcctgcgggaggccatc cgcactctgattggctatggatacaacattgagccctcggaccaggaaggcgggcaagtg gttgagcggctcagcatcgacagggtccgcttcttcagagtggagaggacatacgctgtg aagaccgggaagtggtactttgaatttgaggctgtgacgggaggagatatgagagtgggc tgggccagacctggatgtaagccagatgtggagcttggcacggatgagcttgctttcgtc tttgatggatacaggggtcactgtctaaacatgggcagccgtttgttcgggcggtgctgg catgctggagacgtcgtgggctgtatgatcaacatggaggacaagtccatgatcttcacc cttaatggagagatcctcatcaccaccaagggctctgaactctgcttcactgactttgaa actgaggatgggttcattccagtgtgtagtctcggtctggctcaggtggggcgtatgaat cttgggaaagacgccagcaccttcaagtactacaccatgtgcggccttcaggagggattt gaaccctttgctgtcaacatgaaccgagaggtcaccatgtggttcagcaagcggctgcct acttttgtcaatgtgccgaaggaccacaaccacatcgcagtaaccaggattgacggcacc attgacagccccccgtgtcttaaagtcacccacaagacgtttggcacccagaacagcaac gcagatatggtgttttgtcgtctcagcatgccggtagagttccactccttcttcaaatcc agttctgttgtagacatgaacggagtccatgaggaagatacccttaaagttaaacacaga tatccattgagatctgtgaggcacagtgatgaaagcagacgagtggactacagcagcatc actacgtactaccactcggtaagggtcttcgcaggtcaggaccctgccggtgtgtgggtt ggatgggttacccctgattaccattactatagcaacaacttcagtctcagtaaaaaccga tcggtcactgtaaccctgggtgatgagcgaggacgagtccatgagagtgtgaaaaggagt aactgctacattgtgtggggtggtgatgtgaccagcgccactcacacctccagtcgcagc aacgtggacctggagattggctgtctgatagacctggccactggcctggtgacattcact gtcagtggcaaggagataaccacatcctaccaggtggaaccaaacaccaagcttttccct gctgtgtttgtgcgacccactagccctaacctcttccagttcgagctgtcaaaaatcaag aatgccatgcctctgtcatccgccatttttaaaagtgaacataagaacccggtgccccag tgtccaccccgtctatatgtccagaccatcagcgccgtgctgtggagccgcatgcccaac accttcctcaaggtggaaacagccagggtcaacgagagacatggctgggtagtccagtgt gtggagcccctacagatgttggctgtacatatacctgaggagaacaggtgtgtcgacatc atggagctgtctgagcaggaagacatgaggaggttccactaccacaccctgaagctctac tgtgccctctgcgctctgggcaacactcgtgtagcccacgccctctgcagccacctggac caatcacagctcttatacaccatcgacaatcagtacctgtcgggcatgttacgtgagggc ttctacaatgtcctgatcagcacccacctggagacagcaaaagaagcgcgactcatgatg aaagatgagttcatcatccctgtgacggctgagacacgttccattcgcctcttctccgat gcttccaaaaagcacctcccaccaggggtggggcttagtacctcactcaaaccccgcctc aactttgccccgccctgtttcatcagcaccaaacgggagcaacatctctacagtccccaa atcccactgggcgcattgaaggagaaatcaatatcaatgttgacggaggccgttcagggt ggcggccaccacatccgagatcctgtaggaggaggggtggagtaccagtttgtgccaatc ttgaaactcatcagcaccttgttgactatgggtgtactaggtagcgaggacgtccataag atcttactgctcattgacccaaatgttttcagacagacacgtgaggagggggctacagga gccacagataaagaaggactgacaggggcagaggagaaggcagtggaagctggagaagag gaggtcgccaaagaggctaaacagccaatgaaaggactgctggagaagcggctgcctgag cccgtcaaacgacagatgtgtgagctgcttcactatttctgcgactgcgagctgaagcac cgcatcgaggccattgtgtctttctctgacagcttcgtgtccaagctgcagtacaaccag aagttccgctacaacgagctgatgctggccctcaacatgtctgctgctgttactgcaaag aagaccaaagagttcagatcgccccctcaagaacagatcaacatgctgctgaccttcagt gtgggcgaggactgtccgtgtccaacagacatccaagaggaactgtatgattttcacaac cagctgcagcttcactgtggaatccctatggaggaagacgaatacgagcaagctacatcg atcaaaggtcgcctgctgatgctggtgaacaagatcaaaggccagtcccacaaagcggag gagcccacagagaaggagcaagccgcaccctctaatctgaaggagctgatctctcagacg atggtcagctgggcccaggagtgtcacgtcctggactcagagctggttcgcaagatgttc agcctactgaggaggcagtatgacagcatcggggagctgctccgggccatgaggaagact tacacaatcagtgctgcctccatccaggacaccatcaacctcctggccgccctcggtcag atcagatctttgctgtctgtccgaatggggaaagaggaggagaagctcatgattgatgga cttgctgacattatgaacaacaaagtcttctaccagcaccccaacctaatgagaatactg ggcatgcatgagactgttatggaggtcatggtcaatgtgctcggaggacacaagtcccag gaaattgctttccccaagatggtggccagctgctgtcgcttcctgtgctacttctgtcgg atcagccgtcagaaccagaaagccatgttcgaccacctcagctacctgctggagaatagc agcgtgggcctcgcttcaccagcaatgaggggctccactcctctggatgtggctgcttcc tcggtgatggacaacaatggtctggctctggcactggaggagcctgatctggacaaggtt gtcacctacctagcaggctgtggtctccagagttgtccaatactcctggctaaaggttat ccagacatcggctggaaccccattgagggggagcgttacctttccttcctacgctttgct gtctttgtcaacggcgagagcgtggaggagaactccagcgttgttgtgaagctgctcatc cgtcgtccagagtgttttggacctgccctgaggggggagggagggaacggactgctggct gccatgaaggaagccatcaagatctctgaaacgccggctctggacctgccgggctctgtg catggagtcagctctgacgtgtctgctgatggtgacgatgaggaggaggtggtacacatg ggcaatgccatcatgtccttctactctgccctcattgacctgttgggacgttgcgcccca gagatgcatcttatcaacaaggggaaaggtgaagctctgcgtattcgtgccatcctgcgc tctctggtgccgactgaagacctcgtgggaattatcagcatacctctcaaaatgcccatc cccaacaaagatggctcggtgactgagccggacatgtcagcctgcttctgtccagatcac aagtcccccatggtgctgtttctggacagggtgtacggtatcgaggaccagagctttctg cttcacctgctcgaagtgggcttccttcctgacctgagggctgctacctctctggatacg gagggtctgtgtaccactgagacagccctggccatgaaccgcttcatcggctcagccatg ctacccctcctcacccgctgcgcccctctctttgccggcaccgagcactacgccaccctc atcgattccactctgcacaccatctaccgcctttccaagggccgttcactcaccaaggcc cagagagacgcaatagaggagtgcctgctggctgtctgcaagcaccttcgtccctctatg ttgcagcagctcttgcaccgcctcgtctttgatgtgcccttgctgaccgattactgcaag atgcctctcagactgctcaccaaccactacgagcagaactggaagtactactgcctccca ttgggctggggcagctatggcacagcatccgaggatgaactactgctcaccaagaaaatc ttctggggagtatttgattctctgtcacagaggaaatatgacgcagagctattcaagatg gccatgccttgcctcagtgccatagctggagctttgccaccggactacgtggacgcctcc attagtaccactgtggagaagcctgtttctgtagatgctcagggcaactttgaccccaaa cccatcagtactgctaacattgctcttccagagaagcttgagcactttgccaataaatac gcagagcactcccatgagaaatggtcagcagagaaggtgctgctgggatggaaatatgga gactgtgtggatgagaaggccaagattcaccctcagctcagaatttacaaagccctgaca gagaaggagaaagagatttacagatggccaattagagagtccatgaagagtatgctggca atgggctggagcattgacaggactaaggatggagaaagcatgtctcaacagagggagaat gagaaaatgcgaaagatctctcaagcttcacaggcaaatggcttcaatccgagccccata gacacaagcaacgtggttctgtcaagagaattgcaggggatggtggaggtgctggctgaa aattaccataacatctgggccaagaagaaaaagtgcgaccttggaagtagaggtggggga acacaccctctgttggtgccctatgacacgctgacggccaaggagaaggcccgtgatcgg gagaaggcccaggaccttttccgcttcctgcagatcaatggctatagcatcacgaggggt ttgaaggatttagagcaggattcctcttccatggagaagaggttcgcttacaagtttctc aagaagctgctcaagtatgtcgactcagctcaggagttcatcgcccacctggaggccatg gctgccagtggcaaaacagacaggtctcctcacgaacaagaaatcaagttttttgccaaa gttctccttcctctcatcgaccagtacttcaagaaccactctctctacttcctctcctcc cctagtaagaacctgagcagcagcggttacgcctccaacaaggagaaggagatggtcacc agcctgttttgtaaactggcagctcttgtcagacataggatttctctctttgggagcgac tccactaccatcgtcagctgtctgcatatcctggcacacaccctggacaccaggacggtg atgaagtcgggctcggagctggtgagggtggggctgaggacgttctttgagaacgccgca gaggacctggagaagacgttcgagaacctgaagctggggaagttcactcactctcgctcc cagatgaaaggcgtgtcgcagaatatcaactacaccaccgtagctctgctccccatttta actgctctgtttgaacacatcactcaacaccactttggagtcgacctgcttttggatgac gtccaagtgtcctgctatcgaatcctaactagtctctatgcactgggtactgggaaaaac atctatgtagaaagacagctaccagctcttggccagtgtctggccactctggccggggcc atgcctgtggctttcctggagccaatactcaacacatacaatccctgctccgtctttaat actaagagtgcccgagaacgagccaacctaggcatagcagactccgtcaaggagatgtgt cccgggatgccgcggctagacggtctgatgaaggacatcaatgacatggctgagtctgga gcgcgctacacagagatgcctcacgttatcgaggtggtgctgcccatgctgtgtaactat ctgtcttactggtgggagagggggcccgagaaccagccagccagcggggtcagcgtctgc tgcaccaccgtcacctcagaaaacctcagcctcattctcggcaacatcctcaagatcctt aacaacaacctgggcatcgatgaggcctcctggatgaagaggattgcagtgtacgtgcaa cccatcatcagcaaggcccgtgcagacctgctgaaaagccacttcctgcctacactcgag aagctgaagaagaagacagtgaaggtagtgtctgaggaagagctgttgaaggctgacagt aagggtgacacccaggaggcagagctgctcatcctggacgagtttgccgtgctctgcagg gacctttacgccttctaccctatgcttatccgctatgtggacaacaacaggtcaaggtgg ctgaaagaaccagatgtggactccaatgagctgttcagaatggtcgctgagatatttatc ctctggtgcaagtcacacaatttcaaaagagaagagcagaactttgtggtccaaaatgaa atcaacaacctttccttcttgaccggggataataaaaccaagatgtctaagtctggcgga caagaccaggagaggaaacacaagaaaaggcgtggtgagttctactctatccagacctcg ctgattgtggctgctctgaagaagatgctgccaatcggcctcaacatgtgtaccccagga gaccaggagctcatctctctagccaagactcgttacctcctgagagacacagatgaagaa gtcaaagatcatattcggcagaatctgcatcttcgagaaaagtcagaggaccctgcagtg aggtggcagctaaacctgtacaagaacataacgatgagaagcgaggggcctccggaccct gagagggtggtggaccgtatccagagaatatctgctgctgtcttcaacctggagcaggtg gagcagccattgagatccaagaaatgtgtatggcagaagttgctgtccaagcagaggaag cgagcggttgtcgcctgcttccgaatggctccactttataatctgccacggcatcgctct attaacctcttcctcctggcctatcagagaatatggatagaaacagaggagtactctttt gaggagaagctagtgcaggatcttgcaaaaacgcagcctaagatggaggaagaggaagag gaggaggtcagaaagcagccagaccctctccaccagctcattctgcatttcagccacaac gctctgactgagtgcagttctttggaagaggatcccttgtatattgcatatgcagatatg atggcaaagagttgtgatgaaggtgaagaagaagaagatgttgaagggaaagagaaaaca tttgaggaaaaggaaatggagaagcaaaagatgctgtaccagcaagccagactacatgac cgaggagctgcggagatggtgcttcagatgatcagtgccagcaaaggtcggcttggtgct atggtgactttcaccctcaaactaggcatctctgtcctcaacgggggaaacatcctggtg cagcagaaaatgctggactacctgaaggaaaaaagagatgttggctttttcaaaagtttg tctggactgatgatgtcttgcagtgtcctggacttaaatgcatttgaaaggcaaaataaa gctgaaggtttggggatggttactgaagaaggatcaagttccaaggttctgcagaatgat gagttcactaaggatctctttaggtttctacagcttctctgtgagggccacaacaatgat tttcaaaactttctgaggactcagacagggaacacaactactgttaacatcatcattagt actgtagactacctactaagactccaggaatccatcagtgatttctactggtactactct ggtaaggatattatagatgaggcaggtcagaggaacttctcccaagcactggcagtggct aagcaggtcttcaactctttaactgagtatatacagggtccatgtatcgggaaccaacag agtctggctcacagcaggttgtgggacgcagtagtcggcttcttgcatgtttttgccaac atgcagatgaaactatcccaggactccagtcagattgaattattgaaggagctgctggac ctgcagaaggacatgatcgtcatgatgctctccctactcgaaggtaatgttgtcaatggt actattggcaaacaaatggtggacaccttggtggaatcttccagcaacgtggagatgatc ctgaagtttttcgacatgttcctcaagttgaaggacctgactacatcggacagctttaag gagtatgaccccgagaggaaaggggtcatctcaaagaaagatttccagaagtccatggag aaccagaaacagtattcgcagtctgagattgagtttcttctctcctgcgctgaggctgac gagaacgacatgttcaactacgagcagtttgtggagagatttcatgaacccgccaaggac attggctttaatgtagctgtgttgctgactaatctctctgagcatatgcctcatgatgct cgcctctcaacgttcctcgacctggctgagagtgtcctcagctacttcgagccttattta ggtcgcattgagatcatgggtggagccaagcgcatcgagagagtctactttgagatcagt gagtcaagtcgcacacagtgggaaaagcctcaggtgaaagagtcaaagcggcagtttatt ttcgatgtcgtcaacgaaggcggggagagcgagaaaatggaactctttgtcaacttctgc gaggacaccatcttcgagatgcagctggcctctcaaatttccgagccagacccagcggag cgtccggaggaagatgaggtcgacaaccagagtgtggtggaaaagcagcagcaggaggag gaagaggaggagagtgtgatgttggagtcttcctcagcttttacaatcgcctgcgtctcc atgaaaaaaagcctctgccacttccgccagctgctcactctcaagagcatgaggcggcag tacagaaagttcaggaagatgagcgttagggagatggtgcgaggcttcttctctttcttc tggatgatcatcacaggcctcttccactttgtctacagcctggtttggggattcttccac atcttgtggaccaccatgttcgggggtggcctcgtcgaaggggccaagaacatgaaggtg acggacattttgggaaacatgccagaccccacccagtttgggatccacggagacgtgttg gagatggagaagatggaggcgagtgaagcgtcagcgttggcggagatgggtcagatggct cagggagatgcagcagaggcagacctgatggctgagttgctgaacatacagcccaagaag gagggaaagcacggggctgagccaggcttgggggatgtgtcagaggtggtggtgggggat gctccgtccattgccagcgctgttaagcagaagaaggcacagttggctgcaaagaagaga gctgtaaatggagactacaaatcagattcagagaaaggagattcagaagatggtgagaaa aaggaccatgacaaggccaaagacgaaggccctccagagccaccagtggagaagaaagcc ccgaagaagaggatcggccacaagaaagaactaccagaggtcttcatggccagtttcttc gctggcttggaaatctaccagaccaagatgctgaattaccttgccagaaacttctacaac ctccgcttcctggcactttttgtcgcctttgctatcaacttcattctgctcttctacaaa gtggccggtgattactcagacgatgaagacccctgggatggtcgaggcagaaccagggag gaggaggaggaagatgaggctgcacttgagtatttcgtcctgcaggagagcacaggttac atggcgccaacgcttcgctgtctggctatactacacactatcatatctttcctgtgtgta gtgggatattactacctgaaggtgcccctggtagtgttcaaacgtgagaaggagattgcg aggaagttggaatttgccggcctttacatcacagagcagccgtcggatgatgacatcaaa ggacagtgggacagactggtcatcaatactctttccttccccaacaactactgggataaa ttcgtcaaacgcaaagtgatcaaaaagtatggagacctgtatggagctgagaggatagca gagttgctggggatggataagagtgccttggatttcaaccctacagaggaaaccgttgtc aaggaggcttcactagtgtcatggttgagctcaatcgacacaaagtaccatgtctggaaa ttgggagtggtgtttacggacaattcattcttgtatctagtgtggtacaccaccatgtcc atcctgggccactacaacaacttcttctttgctgctcatctgctggatatcgccatgggg ttcaaaacccttcgcaccatcctctcctccgtcacacataacggcaaacagctggtgttg acagtgggcctgctggcagttgtggtctatctctacactgtggtggccttcaacttcttc aggaagttctacaacaagagtgaggatgaggatgagccagatatgaagtgtgatgacatg atgacttgttacttgttccacatgtacgttggggtgagagcaggagggggcattggggat gagatcgaggacccagctggggacccctatgagctctaccgcatcctttttgacatcacc ttcttcttcttcgtcatcgtcatcctcctggccatcatccagggtttgatcattgatgca tttggagagctgagagaccagcaggaacaagtcaaagaggacatggagaccaaatgtttc atttgtgggatcggtaatgactactttgacacaacccctcacggcttcgagactcacacc ttacaagagcacaatttggccaactacctgtttttcctgatgtaccttatcaacaaggat gagacagagcacactggccaggagtcatatgtgtggaagatgtaccaggagcgatgttgg gatttcttccccgctggagattgcttccgcaaacagtacgaagatcagctcggatag

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