Perca flavescens (yellow perch): 114572785 Help Entry 114572785         CDS       T07494                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism pflv  Perca flavescens (yellow perch) Pathway pflv04020   Calcium signaling pathway pflv04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:pflv00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     114572785 (ryr3)    04020 Calcium signaling pathway     114572785 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pflv04040]     114572785 (ryr3) Ion channels [BR:pflv04040]  Voltage-gated cation channels   Ryanodine receptor    114572785 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 EF-hand_1 Med16_bridge Motif Other DBs NCBI-GeneID:  114572785 NCBI-ProteinID:  XP_028460341 LinkDB All DBs Position 18:complement(24130586..24256533) Genome browser AA seq 4852 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVANIQKEHRKFCLAAEGLGNRVCYLESTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTGPNSEGSADHEKWGGQGGGHRTLLYGHAILLRHSF SDMYLTCLKTSRSLTDKLSFDVGLQEDTIGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSFSNGNISVDASFMQTLWNVQPTCSSGNVAVGYLTGGHVMRLCHGHDESLT IPGADKSQEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQAFRLRHLSTGHYL ALTEDRGLVLQDRDKSDTTSTAFCFRASKEKGDTGPKRDIEGMGVPEIKYGDSVCFVMHV ATGLWLSYLAPDAKSSRLGPPKRRACLHSEGHMDDGLILQRCQREESRAARIIRNTTLLF ANFIKALDSLAEGESMAVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQD LFKEEGMLVLLSICIDRMNLYNSSAHFGEVAGEEAGAAWKDILNLLYELLAALIRGNRNN CTQFSRKLDWLVSKLERLESSSGILEVLHCILVESPEALNIIQRGHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRTNQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVAEGS AQYKKWYFELVTDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSF DGLHLWSGRVPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGL FFPVVSFSAGVKARFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMNVEPVKDYKRDHEGV RDLLGTTTFLSQASFIPTPVDTSQIVLPPHLDNVRDKLAENIHELWGMNKIELGWTYGKV RDDNKRQHPCLVDFSKLPETERNYNVQMSSETLKTLLALGCHVSQVYVNAEDDLKKIKLP KDYMMSNGYKPAPLDLSDVKLTAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQESLHTMEDENVENIRFFR VEQTYAVKTGKWYFEFEALSGGDMRVGWARPGCRPDVEMGTDDQAFVFDGYRGRRMHAGS RYFGQTWKKGDVVGCMINMEDKSMIFTLNGELLITSKGSELCFTDFETEDGFIPVCSLGV SQIGHINLGKDASTFKYYTMCGLQEGFEPFGVNMNREITMWFSKRLPTFVNIPQDHMHIE VTRIDGTVDSPPCLKVTHKTFGTQNSNSDMVYCRLSMPVEFYSADKLLDESLKLSHPPKE DGTVDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFSLAKTRTVTVTLGDERG RVHESVQRSNCYMVCGADAVGPSSSSRSNSDLEIGCLIDLATGLVSFTANGKELSATYQV EPNTKLFPAVFVLPTSANLFQFEFVKIKDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVS VLWSRMPNTFLNVETARVSERHGWVVQCLEPLQMIAVHIPEENRCLDILELSEHEDLKKF HYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLISIHLET AKEARLMMNSEFIIPVTDETRSIKLFPDESKRHSLPGVGLSTSLKPRVNFSAVGIINTKR QQFLYSPQIPLGILKEKAISMLTEAVQGGGTHIRDPVGGSVEYQFVPILKLIGTLLIMGV LTSDEVRLILLLIDPNVFGEAKEGQEAKGDEVAVVGEKEEVSKNEEKAVEAGEEETKESK PQVKGLLEKSLPESVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQFNQKFRYDEL MLAFNMSAAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQEELNSFHEELRLHCG IPVEEEEEEQDTSIKGRLLALLYKIKGPPQKTEEEPTEKEQAAPTNLKELISQTITSWAQ ESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLLVSLGQIRSLLS VRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEITFPK MVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNN GLALALEEPDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFVVFCNGE SVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMEEAIKISNDPALDLPSTPAVVTTG SGEEEGEIIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTTDLV GIISIPLKMPVLNKDGTVTEPDMSASFCPDHKAPMVLFLERVYGIEDQSFLLHMLEVGFL PDLQASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFSSTEHYAQLVDSTLQTIY RLSKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPMLTEYCRIPLGLLTSH YERNWKYYCLPSGMGSFGIASEEELLLTKKLFWGIFDSLSQKKYDADLFKMAMSCLCAIA GALPPDFVDASLGATLEKQASVDAQGNFDPKPVNTANISLPEKLEYIANKYAEHSHDKWS SEKVSAGWKHGDSFDEQAKTHPLLKPYKALSEKERETYRWPVRESLKSMLAMGWNIERTK EGDAMLQQQESEKQRKISESQINEFSPAPMDLHNVNLSRELQGMVEVVAENYHTIWAKKK KTELVSKGGGTHPLLVPYDTLTAKEKYRDREKAQELFKFLQISGYAVIRGLKDIEQESSS MEKRFAYKFLKRLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLTDQTL KNHCLYFLSTPSKNLSSCGCASNKEKEMVTSLFCKLAALVRHRISLFGSDSAMMVSCLHI LTHSLDTRTVMKSGSELVKAGFRNFFENAAEDLDKLLEMLKLGKFMQSRAQMKSVTQSIN YVTVALLPILTALFEHITTYGFGVDLLLDDVQLSCYRILNCLYSLGTGKNIFVERHLPAL GETLAILVGAMPVAFLEPQLNAHNPLSVFNTKTPRERAILSMPDTVEEMSPEMPHLDRLL KDVSDVSESGARYSDVPQVIEVILPMLCNYLSYWWEKGCENSPPGANCCTKVTSEHLSII LGNILKILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTLDKLRKKTVKVVAE EELLKADGKSDNQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRCRWLKEPDADSTELF RMVAEIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKAKMSKSGGDQERKHKRRRGE YYSIQTSLIVAALKKLLPVGLNMCTPGDQELISLAKMRYSLKDTDEEVKEHLRQNYHLQD KSDDPAVQWQLNLYKDVVVKSEEPANSEHTVDRVQSISAAVFHLDQVELPLRNKKSVMHK LLSKQRKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPM KIVEEEEEEVAEMQPDPLHQLILHFSHNALTERSHLEEDPLYIAYADMMAKSCAEDEEEE EEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISSSKGRLGPMVSCTLKLGISI LNGGNVQVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGS IHTQRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLR LQESISDFYWYYSGKDVIDETGKFNFSKALDVAKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMV DTLVESSNNVEVILKFFDIFLKLKDLTSSDSFREYDPECKGIISKKEFQKSMESQMQYSQ SEIEFLLSCAEADENDMFSYKEFVERFHEPAKDIGFNIAVLLTNLSEHMPHDSRLATFLD LAESVLGYFEPYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEG TESEKMEMFVNFCEDTIFEMQLASQISEPDVGEQPEEEEEEEAHGVMDEVAGEEEGALES ASAFTTACRSVKKKIGHVCQIFTVKNVRKQFKKIKKLSIKEIITSFFSFFWMLFTGFFKG IYGLIFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDVTEGEKVEAIDS TGSLDDAISPAGDLAEMDAMLEMLSNPKREGGKHLELGLGDVSELSAEMSTTVQKKAAAK PVVTPENEPEKADTENQEKEDKPKEEAKEPVAEEKPKTKSSQPKGATPAFMLSIVAGLDV LMTKIVNYLARNFYTLRFLALFVCFAINFILLFYKVTEPDKEIDEESTWDGEEEDDENTL FDMDEFSLQESTGYMLPTLRFLAIFHTVISLVCLVGYYCLKVPLVVFKREKEIARKLEFD GLYITEQPSDDDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDLYGAERIAELLGLD KSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKMGVVLTDNYFLYLIWYATMSVFGHFN NFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNK SEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFVI VILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNL ANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14559 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaagacgagatccagttcttgagaactgatgacgaggtg gtgctccagtgtgtggccaacatccagaaggagcatcgcaagttctgcttggccgctgaa ggactcggaaaccgtgtgtgttacctggaatccacatctgaagctaagtatgttcctcca gacttgtgtatttgtaactttgtgttggagcagtccctgtcggtgcgggccctgcaggag atgctggctaacacagggccgaacagcgaagggagtgctgaccatgaaaaatgggggggt caggggggtggacaccggaccctgctctacggtcacgccatcctccttcgccactccttc agtgatatgtacctgacctgtctgaagacatccaggtctctgacagacaagctgtcattt gatgtcggactacaagaagatactataggagaggcctgctggtggaccatccaccctgcg tccaagcagagatccgagggagagaaagtccgcatcggagacgacctgatcctagtcagc gtgtcgacagagagatacctgcatctctccttctccaatggcaacatcagtgtggacgcc tccttcatgcagaccctgtggaatgtccagcctacctgctcttcaggcaacgtggctgta ggctatctaactggtggacatgtgatgcgtctttgtcatgggcatgatgagagcttgacc atccctggagctgacaagagtcaggaggagcagaggatagtcaactatgaagctggcaag ggagcgtcaagggcccgctcactctggagactggagcctctccggatcagctggagcggt agccacatccgctggggtcaggccttccgactacgccacctctctactggccattacctg gccctgactgaggaccgcggactggtcctgcaggacagggacaagtccgacaccacgtcc actgccttctgcttcagggcctccaaggaaaagggtgacactggcccaaagagggacatc gaaggcatgggagtaccagagatcaagtacggagactctgtctgcttcgtcatgcatgtg gcgacaggactgtggctttcttacctggcgcctgatgccaaatcatctcgcctaggaccc ccgaaaagaagggcgtgcctgcattctgagggccacatggacgatgggcttatcctgcag cgctgtcagcgtgaagagtctcgggctgctcgcatcatccgtaacaccacgctcctcttt gccaactttatcaaggctttggacagccttgcggagggtgagtccatggccgtagccggt tatgttgaagaggtgctgcagacattgaacgacctgatcgagtacttcaaacagcccgat tcagagctggagcacgaggagaaacagtgtcttctccgttcactcatcaaacgtcaagac ctcttcaaagaggagggcatgctggtcctcctgtccatatgcatcgaccggatgaacctg tacaacagttctgcccattttggagaggttgctggggaggaggcgggcgcagcatggaag gacattctcaacctcctctatgaactcttggccgcactgattcgtgggaacagaaacaac tgcacccagttttcccgcaaattggactggttggtcagcaaactggagagactggaatct tcatcagggatcctggaagtcctccactgtatcttggtggaaagtccagaggctctgaac atcattcagagaggtcacattaaatccatcatctctctgctctacaagcatggacgcaac cacaagattctggatgtcctgtgttccctctgtgtttgtaacggggtggcagtgagaacc aatcagaatctgatctgtgacaacctgcttccaaagagggacctgctgcttcagactcga ctggtcaatgatgttcagagtatgaggccaaacatcttcttgggcgtggctgaaggttca gctcagtataagaagtggtattttgagctggtgaccgaccaggtggaccactttgtaacc ggagagccgacccacctgagggtaggctgggccaacactaaaggctacgctccgtacccc ggtggaggagagggatggggtggcaacggtgtcggggatgacctctactcttacagcttt gatgggcttcatctctggtcaggccgagtcccgagggccgtggcctccattaaccagcac ctgctgaactcagatgatgtggtcagctgctgtctagatttgggcgctcccagcatgtcc ttcaggatcaacgggcagcctgtccagggcatgttcgaggacttcaacaccgacggatta ttcttccccgtcgtcagcttctctgccggtgtcaaggcccgtttcctgttgggtggacgc cacggagattttaaattcctgccacccgctggttactctccatgctacgaggcgctgttg cccaaagagaagatgaatgtagagcctgtgaaggactacaagagggaccatgagggggtc cgtgacctgctgggaaccaccacgttcctctctcaggcctccttcatccccactcctgtt gacaccagccagattgttcttccccctcacctggacaacgtccgggacaagctggcagaa aacatccacgaactgtgggggatgaacaagattgaactgggctggacctatggcaaggtt cgtgatgacaacaagaggcagcacccttgccttgtggatttcagcaagctgcctgaaact gaaaggaactacaacgtgcagatgtctagtgaaacacttaagaccctgttggcgcttgga tgccatgtttcccaggtctatgttaatgctgaggacgatctgaagaaaataaaacttccc aaagactacatgatgtctaatggttataagcctgcgccactggacctctctgacgtgaaa ctgactgcaggtcaggaggttctagttgataaactggccgagaatgcacacaacgtgtgg gccaaagacagaattaaacaaggatggacctatggcatccagcaggatctgaagagcagg cgtaatcctcgcctggtgccatacgctttactggacgaacgcacaaagaaatctaacaga gacagtctgagagaggccatcaggaccatggttggatatggatatgacattgacccccca gaccaggagtccctccatacaatggaagatgagaacgttgagaacatccgcttcttccgt gtggagcagacgtatgcggtgaagacgggaaagtggtactttgagtttgaggccctgagt ggaggcgatatgagggttggctgggccagaccaggctgcaggcccgatgtcgaaatggga acggatgaccaggccttcgtctttgatggatacaggggtcgacgtatgcacgcaggcagc cgctactttggacaaacttggaaaaagggtgacgtggtcggttgtatgattaacatggag gacaaatccatgattttcaccctaaacggagagctcctgatcaccagcaagggctctgag ctatgcttcactgactttgagacagaggacggtttcatccctgtgtgcagtttgggtgtg agtcagattggacatataaacctgggcaaggacgccagcacgttcaagtactacaccatg tgtggtctccaggaagggtttgagcccttcggtgtcaacatgaacagagagatcaccatg tggttcagcaagcgccttcccacctttgtcaacataccccaagaccacatgcatatcgag gtgacgaggatcgacggaacggtagacagccctccctgcctcaaggtcacccacaagact tttggcacgcagaacagcaacagtgacatggtctactgtaggctgagcatgcctgtggag ttctactcggcagacaagttactggacgaatcactgaagctcagccatcctccaaaagaa gatggaactgttgactatggaagcatcacaacttactaccactcagtgagagtgtttgct ggacaggaccctgcgtcagtgtgggtgggttgggtcacaccagactatcattactatagc aaaaacttcagcctcgccaagacgcgaacagtcaccgtcaccctgggagacgagaggggc cgggtccatgagagtgtccagaggagtaactgctacatggtgtgtggagcggacgcagtc ggcccgtcttcctccagccgctccaactctgacctggagatcggctgtctgatcgacctg gccactggcctggtgtctttcactgccaacggcaaggagctgtccgcaacatatcaggtg gagccaaataccaagctgttcccagctgtgtttgtactccccaccagtgcaaaccttttc cagtttgaatttgtgaagatcaaggatgcgatgccgctctcgtctgccatatttaagagt gagcacaggaacccagtgccgcagtgcccgccacgtctagatgtgcagaccatcgtgtcc gtgctgtggagccggatgccaaacaccttcctcaacgtggagactgctcgggtcagcgag aggcacggctgggtggtccagtgtctggaaccgcttcagatgatagccgtacatatacct gaggaaaacaggtgtttggacatcctggagttatcggagcatgaagacctgaaaaagttc cactaccacacactgaagctgtactgtgccctgtgtgccctgggaaacacccgagttgct cacgccctctgcagccacttggaccaatcccagctcctctacacaattgacaaccagtac ctctctggcatgctgagagagggcttctacaatgtccttatcagcatccatcttgagact gcaaaggaggctcgtctgatgatgaacagcgagttcatcatccctgtgacggacgagact cgctctatcaagctgttccctgatgagtccaagcggcactcgctgcctggcgtgggcctg agcacctccctcaaacctcgggtcaacttctccgccgtcggcatcatcaacacaaagcgc cagcagttcctctacagcccccagattcctcttggcattctgaaagagaaagccatcagc atgctcactgaggccgtgcaaggcggaggaacacacatccgagatccggtaggcggcagc gtggagtaccagttcgttcccatcctgaagctgattgggacactcttaataatgggagtc ctaaccagtgacgaggtgagactgattctcctcctgattgaccccaacgtgttcggagag gccaaggagggtcaggaagccaagggggatgaggtggccgtggtgggggagaaggaggaa gtgagcaagaacgaggagaaggctgtggaggcgggagaggaggagacaaaggagagtaaa ccgcaagttaaaggtctgctggagaagtcgctgcccgagtctgtcaaacgccagatgtgt gagctgctgcactacttctgcgactgtgagctgaagcaccgtatagaggccatcgtctcc ttctccgacagcttcgtgtccaagctgcagttcaaccagaagttccgctacgatgagctg atgctggcgtttaacatgtccgccgccgtcactgccaagaagactaaagagtttcgttca cccccacatgagcagatcaacatcctgttgaatttcagtgcaggagaggactgcccctgc cccgaggagatccaggaggaactcaactccttccatgaagaattgcgactgcactgtgga attcccgtggaggaggaagaagaagagcaggacacttctataaaaggccgtctcctcgct ttactctacaagatcaaaggtccgcctcagaaaacagaggaggaacccacagagaaggaa caggcagctcccaccaacctgaaggagctgatctcccagaccataaccagctgggctcag gagtctcacatccaggacccagagctggtcagagtgatgttcagcctgctaaggaggcag tatgatggcattggggagcttctccgggccatgaagaaatcctacaccatcagtgctgcg tctgtgcaggatgccatcaacctgttggtatcgctaggtcaaatcaggtcacttctgtca gtacgcatgggcaaagaggaggagaaattgatgattgatggactcggcgacatcatgaac aacaaggttttctaccagcatcccaacttaatgagagtgctgggcatgcacgagactgtc atggaggtcatggtcaatgtactgggaggagacaagtcacaggagatcaccttccccaag atggtggccagctgttgtcgtttcttgtgctacttctgtcgtatcagccgccagaaccag aaagccatgtttgaccacctgagctacctgctggagaacagcagtgtcgggctggcctct gaagcaatgcggggctccactccactggatgttgcagcatcttcagtgatggacaacaac ggcctggctttggccctggaggagcctgatttggagaaggtggttacatacctggcaggc tgtggtcttcagagttgtgccatgctggttgctaagggttaccccgacctcggctggaac cctatagagggagagcgctacctgtccttcctgaggttcgtcgtcttctgcaatggtgag agtgtggaagaaaatgccaacgtggtggtgaagctgctgatcaggcgtccagagtgtttc ggccccgccctgaggggagaggggggtcagggtctgctggctgcgatggaggaggccatt aagatctctaatgatcctgccctggacctgcccagtacccccgctgtggtcactactggg tctggtgaggaagaaggcgaaattattcacatgggcaacgccatcatgtccttctactca gctcttattgacctgctgggccgctgcgctcctgagatgcatcttatcaatgcgggtaaa ggtgaggcgctgcgtatcagagcaatcttgcgctctctggttcccacgacagacctggtg ggaatcatcagcatccccctcaaaatgcctgtgcttaataaagatggcacagtgacagaa cccgacatgtcagccagtttctgtccggaccacaaggcccccatggtgctcttcctggaa cgagtgtacggtatcgaggaccagagcttcctgctccatatgttggaggtcggcttcctg cctgacctccaagcctctgcgtctctggacacggaagtgttgagtaccactgaaacggcg ttggccatgaacaggtacatcggctcggccctgctgcctctgctcacccgctgtgccgct ctctttagcagcacagagcactacgcacagctggttgactcaacgctgcagactatctac cggctatccaaaggacgctcactcaccaaagcccaaagggatgccattgaggagtgtctg ctggctatctgcaagcacctgcgtccctccatgatgcaacagctgctcaggcggttggtg ttcgacgttcccatgctcactgaatactgccggatacctctcgggcttctgaccagccac tatgagcggaactggaagtactactgcctgccttctggtatgggcagctttggcatagcc tctgaggaggagctcctcctaaccaagaaactcttctggggaatctttgactccctttcc cagaagaagtatgatgctgaccttttcaaaatggccatgtcgtgcctgtgtgccatcgct ggagccttgcctccggactttgtggatgcaagtcttggagcaacactggagaaacaggca tcagtggatgcacagggcaactttgatccgaaacctgtcaacactgccaacatctccctt cctgaaaaacttgagtacattgccaacaaatatgcagagcattcccatgacaagtggtcc tcagagaaggtgtcagcaggctggaaacatggagacagctttgatgagcaggccaaaacc catccactgctgaagccttacaaagcgctgagtgagaaggagagagaaacataccgctgg ccagtgagggagtcattgaagagcatgctggctatgggctggaacattgagaggaccaag gaaggagatgccatgttacaacaacaagagagcgaaaaacagcgaaagatctctgagtct cagatcaatgaattcagtcctgctccgatggacttgcacaatgtcaatttgtctcgtgag ttacagggcatggtggaggtggttgcagaaaactaccacaccatctgggccaagaagaag aaaactgaactcgttagcaaaggaggagggacccacccactgttggtaccctatgacacc ctgacagccaaagagaagtacagagacagagagaaggcccaggagctcttcaagtttctg cagatcagtggctatgccgtcataagaggtctgaaggacatagagcaggaatcatcatcc atggagaagcgttttgcctacaagtttctcaaaaggctgctgaaatacgtggactcggcc caggagttcatcgctcatcttgaggctatggccaccagtgggaagacggacaaatctcct catgaccaggaaatcaagttctttgccaaggtgttgcttcctctgacagatcaaacttta aagaaccactgtctctacttcctgtccacgcccagcaagaacctgagcagctgtggctgc gcctctaacaaagagaaggagatggtcactagcctgttctgtaagctggcagctcttgtc agacacaggatttctctctttggaagtgactctgcaatgatggtgagctgtctgcacatc cttactcactcacttgacaccagaacggtgatgaagtctggctcagagctggtcaaagcc gggtttcggaatttctttgagaacgcggcagaggacctggataagctgctggagatgcta aaactggggaagtttatgcagtcccgtgcccagatgaagagcgtcacccagagcatcaac tatgtgactgtggcgctgctgcccatcctcactgccctgtttgagcacatcacgacatat gggtttggagtggacctgctgttggatgatgtgcagctgtcctgttaccgaatcttgaat tgtttgtactctctgggaactggaaagaacatctttgtggagaggcatcttccagcgctg ggggagaccctggcaatcctggtgggagccatgcctgtggcgttcctggagccccaatta aacgcccacaacccgctgtctgtctttaacaccaagaccccccgagagagagccatcctg agtatgccggacacggtagaggagatgtctccagagatgcctcatcttgacagactgctg aaagatgtcagcgacgtctcagagtctggcgctcgctacagtgacgtgccacaggtcatt gaagtgatccttcccatgctgtgtaactatttgtcctactggtgggagaaaggttgtgag aactcacctccaggtgccaattgctgcactaaggtgacctctgaacacctcagcatcatc ctgggaaacatcctcaagatccttaacaacaacctgggcattgatgacgccccctggatg aagaggattgctgtctactctcagccaatcatctgcaaggctggagcagatctgctgaga acccacttcctgcccacactggacaaactgaggaagaagacagtgaaggttgtggctgaa gaggagttgctgaaggccgacggtaaaagtgacaaccaggaggccgagctgctcatcctg gatgagtttgctgtgctctgcagagacctctacgccttctaccccatgctcatccgttat gtggacaacaacaggtgtaggtggctgaaggagccggatgcagactccactgagctcttc aggatggtggcagagatcttcatcctctggtgcaagtcccataactttaagcgtgaagag caaaactttgtggttcagaatgagatcaacaatttgggcttcctgacaggagagggcaag gcaaagatgtccaagtcagggggggaccaggagaggaaacacaagcgtcgccgaggcgag tattactccatccagacctccctgatcgtggctgccctgaagaagctcctgccagtcggc ctaaacatgtgcaccccaggagaccaggagctcatctctcttgccaagatgcgctacagt ctgaaagatacagatgaggaggtgaaggagcacttgcgtcagaattaccatctccaggac aagtctgatgacccagcagtccagtggcagctgaacctgtacaaggatgtggtggtaaag agcgaggagcctgcaaactcagaacacacagtggaccgagtgcagagcatctcagctgca gtcttccacctggatcaggtggagctgcctctgagaaataagaagagtgtgatgcataag ctgctgtccaaacagcgtaagcgtgctgtggtggcttgtttccgcatggctccactctac aatctacccaggcatcgcgctatcaacttcttcatcccggcctatcagagactttggata gaggcagaggagtactcctttgaggagaagctagttcaggatctggcaaaaaccccgatg aaaattgtggaggaggaggaagaggaggtggctgagatgcagccagaccctctccaccaa cttatcctccacttcagccacaacgctctgacagagagaagtcacttggaagaagatcct ttgtatattgcgtatgcagacatgatggcaaagagctgtgcagaggatgaggaggaagaa gaggaggaagggaaagaaaagacttttgaggaaaaagagatggaaaagcagaagatcctg tatcagcaggcgaggctgcacgcccgtggggccgcagagatggtgctgcagatgatcagc tccagtaaaggtcgtctgggccccatggtgtcctgcaccctcaaactgggaatctccatc ttaaatggaggcaatgtgcaagtacagcagaaaatgcttgattacctgaaagagaaacga gatgcaggctttttcaagagtctctcaggactgatgcagtcttgcagtgtcttggacttg aatgcatttgagaggcagaacaaagcagaaggacttggcatggtgacagaggagggttca atccacactcagcggggttccaaggtgctacagaatgatgagtttactaaagatctgttc cggtttttgcaacttctgtgcgaggggcacaatggagattttcagaactttctgagaact caaactggaaacacaaccacagtcaacatcattatcagcactgtggactatctgctccgt cttcaggagtcaatcagtgacttctactggtactactctggcaaagatgtcattgatgag actggaaaattcaacttctctaaagcattagatgttgccaagcagatattcaactcactg actgagtatattcagggcccgtgtattgggaaccagcagagtttagctcacagcagactg tgggatgcagttgtaggcttcttgcatgtatttgccaacatgcaaatgaagctgtctcag gatgccagtcagattgagctgttgaaggagctgatggatttacagaaggacatggttgtc atgttgctgtctctgctagagggtaatgtggtgaacggaacaattggaaagcagatggtt gacactctggtggagtcttctaacaatgtggaggtgatccttaagttcttcgatattttc cttaaactaaaggacctgacgtcctctgacagcttcagagagtatgaccctgagtgtaaa ggcattatttcaaagaaggagttccaaaagtcaatggagagccagatgcagtacagccag tctgagattgaattccttctctcgtgtgcagaggccgatgagaatgacatgttcagttac aaagagtttgtggagcggttccacgagccggctaaagatattggcttcaacatagcagtg ctgttgaccaacctgtctgaacacatgccacatgactccagactcgccaccttcttagac ctggcagagagcgtacttggctacttcgagccttatctgggtcgtatcgaaatcatgggc agcgcaaagcgcattgagagggtgtactttgagatcagcgagtcaagccgtgagcagtgg gagaagccgcaggtgaaagagtccaagcgtcagttcatctttgatgtggtcaacgagggc acggagagcgagaagatggagatgtttgtgaatttctgcgaggacacaatttttgagatg cagctggcctcacagatctctgaaccagatgtgggtgaacaacctgaggaggaggaagag gaagaagcacatggtgtcatggacgaggtggctggagaggaagagggcgccctggagtcg gcctcagccttcaccaccgcatgccgctcagtcaagaagaagattggtcacgtctgccaa atctttacggttaaaaatgtgcgcaagcagttcaagaaaatcaagaagctgagcatcaag gagattatcaccagctttttctccttcttctggatgcttttcaccggcttcttcaaggga atctacggcctcatctttgggttcttccatgtcatctggtcctccatgtttggtggtggc ctggttgagggagccaagaacataaaggtgacggacatcctcggaaacatgcctgaccca acccagttcggtatccacggagatgtgaccgaaggagagaaagtggaggccatagattca acaggaagcttagatgacgccatatcaccagcaggcgacctggcagagatggacgcaatg ttggagatgctgtccaatcccaagagggaaggaggaaaacatcttgagcttggcctgggt gatgtttccgagttgagtgcagagatgtccactactgttcaaaagaaagctgctgccaag cctgttgtaacccccgagaatgaaccagagaaagcagacacagagaaccaggagaaggag gacaagccaaaggaggaggccaaggagccagtggcagaggagaagcccaagaccaaatca agtcagcctaaaggggcgacacccgccttcatgttgagtatcgttgctggtctggacgtc ttaatgaccaagattgtgaactacctggctcgtaacttctacaccctgcgttttctggct ctgtttgtgtgttttgccatcaacttcattcttctcttctacaaggtcactgaacctgat aaagaaatcgatgaggaaagcacctgggatggggaagaggaggatgatgagaacacactc ttcgacatggatgaatttagcctgcaggagagcactggctacatgttaccaacgctgcgc ttcctggctatatttcacactgtcatctcactcgtctgtctggttgggtactactgtctg aaggttcctttggtggtgttcaagagagagaaggagattgccaggaagcttgaatttgac ggtctctacatcaccgaacagccgtctgacgatgacatcaagggccagtgggatcgcctc gtcatcaacaccccgtctttccccagcaactactgggacaagtttatcaagcgcaaggtg atcaacaaatacggtgacctgtatggagctgaacgcatcgctgagctcttaggtctggat aagagcgctctggactttgacccaacagtggagactgtagagaaggaagcttccctgctc tcctggctaagctccattgataccaagtaccacatctggaaaatgggcgtggttctgact gacaattactttctgtatctgatctggtacgccaccatgtctgttttcggacacttcaac aacttcttctttgctgcccatctgctggacatcgcgatgggcttcaagacccttcgcact atcctgtcttctgtcactcacaacggcaagcagctcgtgctgactgtgggtctgctggcc gtggtcgtctatctctacaccgtggtggccttcaacttcttcagaaagttctacaataag agcgaggatgaagacgagcccgacatgaagtgtgacgatatgatgacgtgctatttgttc cacatgtacgtgggtgtgagagctggaggtggtattggagacgagttggaggacccagct ggagacccctatgagctctaccgcatcctgtttgacatcactttcttcttctttgtcatt gtcatcctgctggccatcatccagggtctgatcattgatgcctttggtgagctgagagac cagcaggagcaggtgaaggaggacatggagaccaaatgcttcatctgtggcattgggaat gactactttgaccggacgcctcacgggtttgaaacccacaccttacaagagcacaaccta gctaactatctgttcttcctaatgtacctgattaacaaggacgagactgaacacacgggt caggagtcatttgtgtggaagatgtatcaggagagatgctgggacttcttccctactgga gactgcttccgtaaacaatatgaggaccagttgggttaa

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