Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1: PFREUD_13360
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Entry
PFREUD_13360 CDS
T01252
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
pfr
Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Pathway
pfr00290
Valine, leucine and isoleucine biosynthesis
pfr00660
C5-Branched dibasic acid metabolism
pfr01100
Metabolic pathways
pfr01110
Biosynthesis of secondary metabolites
pfr01210
2-Oxocarboxylic acid metabolism
pfr01230
Biosynthesis of amino acids
Module
pfr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pfr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PFREUD_13360 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PFREUD_13360 (leuB)
Enzymes [BR:
pfr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
PFREUD_13360 (leuB)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
CBL56852
UniProt:
D7GE91
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Position
1496886..1497950
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AA seq
354 aa
AA seq
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MSKSSHKPVIAVIPGDGIGPEVVAQAVKVLIAAAGEDTFEFSQYELGAQHWLDTGEVLSD
ETLADLATRDAIILGAVGAAPGSSTIPSGLLERGLLLKLRFEFDQDVNLRPSKIYPGVVT
PLSQAVLDQGPVDFVVVREGTEGMYVGNGGTLRQGTPNEVATEVSINTAFGVERVVRYAF
ELATKRSNKVTLVHKHNVLVNAGGLWSRIVDQVATEYPSVEHDYLHVDAATINLAVDPQR
FDVIVTDNLFGDILTDEAAAVTGGIGLAPSANINTARTYPSMFEPVHGSAPDIAGKGIAD
PTAAISSMALLLTHLGYEKEAQRVNDAVSADISERGIAKRSTVEIGDAIAARLA
NT seq
1065 nt
NT seq
+upstream
nt +downstream
nt
atgagtaagtcttcgcacaagccagtcattgcagtcatcccgggcgacggaatcggcccc
gaagtggtggcccaagccgtcaaggtccttatcgcagcggcgggtgaggacaccttcgag
ttctcccagtacgaactcggggcccagcactggctcgataccggtgaggtgctttccgac
gagaccctcgccgatctggccacccgtgacgcgatcatcctcggtgccgtgggcgctgcg
cccggcagcagcacgattccctccggactgctggaacgcggcctgctgctcaagctgcgc
tttgaattcgatcaggacgtgaacctgcgcccgtcgaagatctatcccggcgtcgtgacc
cccctgtcccaagcggtactcgaccagggaccggtggacttcgtggtcgtgcgcgagggc
acggagggcatgtacgtgggcaatggcgggaccctgcgccaagggacgcccaacgaggtg
gccacggaggtcagcatcaataccgcgttcggcgtggaacgcgtcgtgcgctatgcattt
gagctcgccaccaagcgcagcaacaaggtcaccctcgtgcacaagcacaacgtcctggtg
aatgccgggggcctgtggagtcgcatcgttgaccaggtcgccaccgaatatccttcagtg
gagcatgactacctgcacgttgacgcggcgacgatcaacctggccgtcgatccccagcgc
tttgacgtgatcgtcaccgacaacctgttcggtgacatcctgaccgacgaggccgcagcg
gtgacgggcggcatcggactggctccgagcgccaacatcaacacggcgcgcacctatccc
tccatgttcgagcccgtgcatggttcggcgcccgatatcgccggcaagggcatcgccgac
ccgacagccgccatcagctcgatggcgctcctgctcacgcacctgggatacgagaaggag
gcacagcgggtgaatgacgccgtgagtgccgatatttccgagcgtggaattgccaagcgc
agcaccgttgagatcggcgatgcgatcgcggcccgcctggcctga
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