Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1: PFREUD_15540
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Entry
PFREUD_15540 CDS
T01252
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D-alanine-adding enzyme)
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pfr
Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Pathway
pfr00300
Lysine biosynthesis
pfr00550
Peptidoglycan biosynthesis
pfr01100
Metabolic pathways
pfr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pfr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PFREUD_15540 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PFREUD_15540 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PFREUD_15540 (murF)
Enzymes [BR:
pfr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PFREUD_15540 (murF)
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Ortholog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
E1-E2_ATPase
Motif
Other DBs
NCBI-ProteinID:
CBL57052
UniProt:
D7GEU1
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Position
complement(1703185..1704717)
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AA seq
510 aa
AA seq
DB search
MLRPQTTKNQGQGESDVRVTTTGDLAELVSAHGTPCRLQGSAAVPVGPQVVIDTHQVTPG
ALFVGLPGEHVDGADLAPQAAGAGAAAALVGHDVTAGLPRLIVEDAGRGLSALATGVVAT
ELARGLITFAITGSSGKTSTKDLLAQVLEATGPTVSPAGNHNNEIGVPLSACGVDATTRY
LVSEMGSRGKGDVATLCRIVPPRISTVLNVGTAHLGEFGSQDAIAEAKGEIVEALPADGW
AVLNADDPRVAAMAPRTNAHIARWTTTGAARASDAELFVSADHITTDALQRGSFQLRVTR
GGATSTHPVRLRLIGAHQVLNATAAATMALAAGLDPAAVAASLSTATTRSPLRMELHELR
GGIALINDSYNANPDSMAAALHAVAAMGAARHDEYPRARTIAILGEMGELGTQSARLHAR
VARLAADLGIDIVIALGDHAGTMAQAAREGGAQARAARKEEVADSLELVPGDIVLVKASR
SMALEDITAQLLSLDAATTHHAAGKEELPR
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgcccgcagaccacgaaaaaccaaggacaaggggaatctgacgtgcgtgtcact
actaccggcgatctggccgagctggtctcggcccatggcacgccctgtcgattgcagggc
agtgccgccgtgccggtgggaccccaggtggttattgacacgcatcaggtgacgcccggt
gcgctgttcgtcggcctgcccggcgagcatgtcgacggcgccgacctggccccgcaggcc
gccggtgccggagcagctgcggcgctggtcggccacgacgtcacggccgggcttccccgc
ctgatcgtcgaggatgccggcagaggactgtccgccctggccaccggcgtggtggccacc
gaactggcgcgtggactgatcaccttcgcgatcaccgggtccagcggcaagacgtccacc
aaggacctcctggcccaggtgctggaggccaccggccccacggtcagcccggccggcaac
cacaacaacgagatcggcgtgccgctgtcggcgtgcggggtggacgccaccacgcgctac
ctggtcagcgagatgggttcgcggggcaagggcgatgtcgccacgttgtgccgcatcgtg
ccgcccaggatctccaccgtgctcaatgtcgggaccgcccatctgggcgaattcggcagt
caggacgccatcgccgaggcgaagggcgagatcgtcgaggcccttcccgccgatggctgg
gccgtgctgaacgctgacgacccacgggtcgccgcgatggcaccacgcaccaatgcccat
atcgcccgttggaccacaaccggtgccgcacgggcctccgacgccgaactgttcgtcagc
gccgaccacatcaccaccgatgccctgcagcggggctccttccagctgcgggtcacccgc
ggcggcgcgaccagtacgcacccggtgcggctgcgcctgatcggtgcccatcaggtgctc
aacgctacggctgcggccacgatggcgctggcggccgggctcgatcccgccgccgtggcc
gcatcactcagcacggcgaccacccgctctccgctgcgcatggaactccatgagctgcgc
ggcggcatcgccctgatcaatgattcctacaacgccaacccggattccatggctgcggca
ctgcatgcggtggctgccatgggcgcggcgcggcacgacgaatatccccgggcccgcacc
atcgcgatcttgggggagatgggcgagctgggcacccagtccgcgcggttgcacgcccgg
gtggcccggctggccgccgatctggggatcgacatcgtcattgccctgggcgaccatgcc
gggacgatggcgcaagcggcccgtgagggcggcgcacaggcgcgtgcggcacgcaaggag
gaggtggctgacagcctcgagctcgtcccgggcgatattgtgctggtgaaagccagccgc
tcgatggcccttgaggacatcactgcgcagctgctttcgcttgatgccgctacaacccat
cacgcggccggtaaggaggaactcccgcgatga
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