Propionibacterium freudenreichii subsp. freudenreichii DSM 20271: RM25_1473
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Entry
RM25_1473 CDS
T03860
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pfre
Propionibacterium freudenreichii subsp. freudenreichii DSM 20271
Pathway
pfre00300
Lysine biosynthesis
pfre00550
Peptidoglycan biosynthesis
pfre01100
Metabolic pathways
pfre01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pfre00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RM25_1473
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RM25_1473
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RM25_1473
Enzymes [BR:
pfre01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RM25_1473
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
E1-E2_ATPase
Motif
Other DBs
NCBI-ProteinID:
AJQ91182
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Position
complement(1672123..1673607)
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AA seq
494 aa
AA seq
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MRVTTTGDLAELVSAHGTPCRLQGSAAVPVGPQVVIDTHQVTPGALFVGLPGEHVDGADL
APQAAGAGAAAALVGHDVTAGLPRLIVEDAGRGLSALATGVVATELARGLITFAITGSSG
KTSTKDLLAQVLEATGPTVSPAGNHNNEIGVPLSACGVDATTRYLVSEMGSRGKGDVATL
CRIVPPRISTVLNVGTAHLGEFGSQDAIAEAKGEIVEALPADGWAVLNADDPRVAAMAPR
TNAHIARWTTTGAARASDAELFVSADHITTDALQRGSFQLRVTRGGATSTHPVRLRLIGA
HQVLNATAAATMALAAGLDPAAVAASLSTATTRSPLRMELHELRGGIALINDSYNANPDS
MAAALHAVAAMGAARHDEYPRARTIAILGEMGELGTQSARLHARVARLAADLGIDIVIAL
GDHAGTMAQAAREGGAQARAARKEEVADSLELVPGDIVLVKASRSMALEDITAQLLSLDA
ATTHHAAGKEELPR
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
gtgcgtgtcactactaccggcgatctggccgagctggtctcggcccatggcacgccctgt
cgattgcagggcagtgccgccgtgccggtgggaccccaggtggttattgacacgcatcag
gtgacgcccggtgcgctgttcgtcggcctgcccggcgagcatgtcgacggcgccgacctg
gccccgcaggccgccggtgccggagcagctgcggcgctggtcggccacgacgtcacggcc
gggcttccccgcctgatcgtcgaggatgccggcagaggactgtccgccctggccaccggc
gtggtggccaccgaactggcgcgtggactgatcaccttcgcgatcaccgggtccagcggc
aagacgtccaccaaggacctcctggcccaggtgctggaggccaccggccccacggtcagc
ccggccggcaaccacaacaacgagatcggcgtgccgctgtcggcgtgcggggtggacgcc
accacgcgctacctggtcagcgagatgggttcgcggggcaagggcgatgtcgccacgttg
tgccgcatcgtgccgcccaggatctccaccgtgctcaatgtcgggaccgcccatctgggc
gaattcggcagtcaggacgccatcgccgaggcgaagggcgagatcgtcgaggcccttccc
gccgatggctgggccgtgctgaacgctgacgacccacgggtcgccgcgatggcaccacgc
accaatgcccatatcgcccgttggaccacaaccggtgccgcacgggcctccgacgccgaa
ctgttcgtcagcgccgaccacatcaccaccgatgccctgcagcggggctccttccagctg
cgggtcacccgcggcggcgcgaccagtacgcacccggtgcggctgcgcctgatcggtgcc
catcaggtgctcaacgctacggctgcggccacgatggcgctggcggccgggctcgatccc
gccgccgtggccgcatcactcagcacggcgaccacccgctctccgctgcgcatggaactc
catgagctgcgcggcggcatcgccctgatcaatgattcctacaacgccaacccggattcc
atggctgcggcactgcatgcggtggctgccatgggcgcggcgcggcacgacgaatatccc
cgggcccgcaccatcgcgatcttgggggagatgggcgagctgggcacccagtccgcgcgg
ttgcacgcccgggtggcccggctggccgccgatctggggatcgacatcgtcattgccctg
ggcgaccatgccgggacgatggcgcaagcggcccgtgagggcggcgcacaggcgcgtgcg
gcacgcaaggaggaggtggctgacagcctcgagctcgtcccgggcgatattgtgctggtg
aaagccagccgctcgatggcccttgaggacatcactgcgcagctgctttcgcttgatgcc
gctacaacccatcacgcggccggtaaggaggaactcccgcgatga
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