Pyrococcus furiosus DSM 3638: PF0440 Help Entry PF0440            CDS       T00075                                  Name (GenBank) ribonucleotide reductase   KO K00525   ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] Organism pfu  Pyrococcus furiosus DSM 3638 Pathway pfu00230   Purine metabolism pfu00240   Pyrimidine metabolism pfu01100   Metabolic pathways pfu01232   Nucleotide metabolism Brite KEGG Orthology (KO) [BR:pfu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     PF0440    00240 Pyrimidine metabolism     PF0440  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:pfu03400]     PF0440 Enzymes [BR:pfu01000]  1. Oxidoreductases   1.17  Acting on CH or CH2 groups    1.17.4  With a disulfide as acceptor     1.17.4.1  ribonucleoside-diphosphate reductase      PF0440 DNA repair and recombination proteins [BR:pfu03400]  Prokaryotic type   Other factors with a suspected DNA repair function    Modulation of nucleotide pools     PF0440 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ribonuc_red_lgC Endonuc_subdom Intein_splicing Stirrup LAGLIDADG_3 ATP-cone Ribonuc_red_lgN Hom_end LAGLIDADG_2 PT-HINT LAGLIDADG_1 nec1 Motif Other DBs NCBI-ProteinID:  AAL80564 UniProt:  E7FHX6 A0A5C0XQP5 Structure PDBPDBj LinkDB All DBs Position complement(451759..456981) Genome browser AA seq 1740 aa AA seqDB search MAVEKVMKRDGRIVPFDESRIRWAVQRAMWEVGIRDEKKLDEVVKSIVQRINELYDGKIP HIENIQDIVELELMRAGLFEVAKAYILYRKKKAEIREEKKRILNKKELDEIDKRFSINAL RVLASRYLKKDENGNIVESPRELFERVAILAVIPDLLYDERVFDKNGNYSQDLKRVEYYL EHFEEFDRKYSIGKYKLNKYHFERMVNLYKELAEQGKMKVSIDEFLAMLEKGEFNEYEKE INEYFRLMTNQIFMPNTPALINSGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKMGG GCIDGKAKIIFENEGEEHLTTMEEMYERYKHLGEFYDEEYNRWGIDVSNVPIYVKSFDPE SKRVVKGKVNVIWKYELGKDVTKYEIITNKGTKILTSPWHPFFVLTPDFKIVEKRADELK EGDILIGGMPDGEDYKFIFDYWLAGFIAGDGCFDKYHSHVKGHEYIYDRLRIYDYRIETF EIINDYLEKTFGRKYSIQKDRNIYYIDIKARNITSHYLKLLEGIDNGIPPQILKEGKNAV LSFIAGLFDAEGHVSNKPGIELGMVNKRLIEDVTHYLNALGIKARIREKLRKDGIDYVLH VEEYSSLLRFYELIGKNLQNEEKREKLEKVLSNHKGGNFGLPLNFNAFKEWASEYGVEFK TNGSQTIAIINDERISLGQWHTRNRVSKAVLVKMLRKLYEATKDEEVKRMLHLIEGLEVV RHITTTNEPRTFYDLTVENYQNYLAGENGMIFVHNTGLNFSKLRPEGDIVGTTTGAASGP VSFMHLIDAVSDVIKQGGVRRGANMGILEIWHPDIEKFIHAKEKNIGTNVLSNFNISVGI WEDFWEALKEGKKYPLINPRTGEVVKEVDPKTLFEELAYMAWAKADPGVIFFDVINRRNV LKKAKGGPIRATNPCVVGDTRILTPEGYLKAEEIFSLAKERGKKEAVAVEGIAEEGEPYA YSVEILLPGEEKVEYETVHGKVLAVADPVAVPAYVWKVGRKKVARVKTKEGYEITATLDH KLMTPEGWKEVGKLKEGDKILLPRFEVEEEFGSESIGEDLAFVLGWFIGDGYLNVNDKRA WFYFNAEKEEEIAVRIRDILVKHFGIKAELHRYGNQIKLGVRGEAYRWLENIVKNNEKRI PEIVYRLKPREIAAFLRGLFSADGYVDKDMAIRLTSKSRELLREVQDLLLLFGILSKIYE KPYESEFHYTTKNGEERIYRSKGYYELVITNYSRKLFAEKIGLEGYKMEKLSLKKTKVDQ PIVTVESVEVLGEEIVYDFTVPNYHMYISNGFMSHNCGEEPLYEYESCNLASINLAKFVK YDENGKPYFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTRRIGVGMMGLADAL FKLGIPYNSEEGFKFMRKVTEYLTFYAYKYSVEAAKKRGTFPLYDKTEYPEGKLPVEGFY HPEIWNLPWDKLVEEIKKYGLRNAMVTTCPPTGSVSMIADTSSGIEPVYALVYKKSVTVG EFYYVDPVFEEELKKRGLYSEELLKKISDNYGSVQGLEEIPEDMQRVFVTALDIHWLDHI IAQASIQMWLTDSASKTINMINEATVEDVKAAYLIARFLGCKGVTVYRDGSLSVQVYSVE GEKKKRRFKPKPSEYAKKILLEIVEKEPWIKNFINVDEILNGKKEQLLFSLRPANESKLK VPGREEEVRPGNIPEEKIRELLGVVYCPVCYEKEGKLVELKMESGCATCPVCGWSKCVIS NT seq 5223 nt NT seq  +upstreamnt  +downstreamnt atggcagttgaaaaagtgatgaaaagagatggcaggatagtaccattcgatgagtcacgt ataagatgggctgtacaaagggcaatgtgggaagtaggcatcagggatgagaagaagctt gacgaagtagttaagtcaattgtgcagaggataaacgaactatacgacggcaaaatccca cacattgaaaacattcaagatattgtagagctggaacttatgagagcaggactttttgaa gtggctaaagcctacatcctctatagaaagaagaaagctgaaataagagaagaaaagaaa aggattttgaacaagaaggaactagacgaaattgacaagagattctctataaatgcctta agagtgcttgcgtcgagatatctcaaaaaagatgagaacggcaacattgtagaaagtcca agagagttgtttgagagagtagcaattttagctgtcatccctgatctcctctatgatgag agagtctttgataagaatggcaactattctcaagatttaaagcgcgttgagtactatcta gaacattttgaagaatttgacagaaaatattcaataggaaaatacaagctcaataaatat cacttcgaaagaatggtcaacctatacaaggagcttgcagaacaggggaagatgaaagtc agcattgacgagttcttagctatgttagagaaaggagaattcaatgaatatgagaaagaa attaatgagtactttaggttaatgacaaaccaaattttcatgccaaatactccggcatta ataaattccggaaggcccctgggaatgctctcagcttgctttgttgtcccaatagaggat gatatggagagtattatgaaagcagcccacgatgttgccatgatacagaagatgggagga gggtgcatagacggaaaggccaagataatctttgagaacgaaggtgaggagcatctaacg acgatggaggagatgtacgagagatacaagcatctaggtgaattctacgatgaggaatac aatagatggggaattgatgtttcaaacgttcctatttatgtaaagtcattcgatccagag agtaagagagtcgtcaaaggtaaggtgaatgtgatatggaagtacgagcttgggaaggat gttactaagtacgaaatcattaccaacaaggggactaagatactaacatctccctggcat ccgttcttcgttctgacacctgactttaagatagtggagaagagggctgatgagctcaag gaaggagacattttaatcggcggaatgccagatggcgaagattacaagttcatatttgac tactggcttgctgggttcatagcaggtgacggatgctttgataaataccactcacatgtt aagggacatgagtacatctatgacagactcaggatatatgactatagaattgaaacattt gaaataataaatgactatcttgaaaaaacctttggaaggaagtacagcattcagaaggac aggaatatatactatattgacataaaggcgaggaatataacctctcactacctaaaactc ttagaggggatagataacggaataccaccccaaattctaaaagagggcaagaatgctgtt ttatctttcatagcgggcctctttgatgcagagggtcatgtgagtaataaaccaggtatc gagcttggaatggtaaataaaaggttaatagaagatgttactcattaccttaatgccctt ggaataaaagcaagaataagagaaaagctgagaaaggatggcattgattatgtgcttcac gttgaggaatactcatcactcttaagattttacgaacttataggaaagaatctccagaac gaggaaaagagggagaaacttgagaaagttcttagcaatcacaaaggaggaaactttggt cttccactgaactttaatgccttcaaggaatgggcatcagagtatggagtagagtttaag acaaatggtagccagacgatagcaatcattaatgatgaaagaatttcacttggacagtgg cacacaagaaatagagtctctaaggcagttcttgtaaagatgctaaggaaactctacgaa gcaacaaaggatgaagaagtcaagaggatgctccacctgattgagggtctcgaagttgtg aggcatataacaaccacgaacgagccgaggacgttctacgatctaaccgttgaaaactac cagaactatttggcgggagaaaatggaatgattttcgtccacaacaccggactcaacttc tcaaaactccgtccagaaggagatatagtgggaacaacgacaggcgcagctagtggtcct gtctcgttcatgcacctcatagatgccgttagcgatgtaataaagcaaggtggtgtgaga agaggagcaaacatggggatacttgagatatggcatccagacattgagaaattcatccat gcaaaagagaaaaacattggaactaatgtcttgagtaacttcaacatcagcgttggaata tgggaagacttctgggaggctctaaaggaaggaaagaaatacccactcataaatcccagg accggtgaagttgtaaaggaggttgatccaaagaccttatttgaagagttagcttacatg gcttgggctaaagccgacccaggagttatattcttcgacgttataaacaggagaaatgtc ctaaagaaggccaaaggcgggccgataagggcaacgaatccatgtgtcgttggagacact agaatcctaactccagagggatatctaaaggctgaagagatattcagtttggcgaaagag aggggcaagaaagaggcagtggccgtggagggaatagcggaggagggagagccgtacgcg tattcagtcgagatcctcctgccgggagaagagaaggtagagtacgaaaccgttcacgga aaggttttagccgttgctgatccagttgcggttccagcatatgtgtggaaggttggaagg aagaaggttgcgagggttaagacaaaggaaggttacgagattacagcgactctcgaccac aagctcatgactccagaaggatggaaagaggtcggcaaattaaaagaaggggataagata cttctcccaaggttcgaggttgaagaagaatttggaagcgagagcataggggaagatttg gccttcgttctcggatggttcatcggtgacggctatctcaacgtgaacgacaagagggca tggttctactttaacgccgagaaggaagaggaaattgccgtgaggataagggatatactc gtgaagcatttcggaatcaaggcagaacttcaccgctatggcaaccagataaagctagga gttcgcggggaagcatacaggtggcttgagaacatcgtgaaaaacaacgagaagaggatt ccagagatagtttacaggctcaagccaagagaaatagcggccttccttaggggcctcttt agtgcggatggatacgttgacaaggacatggcaataaggctaacttcaaagagcagagag ctcctcagagaagttcaagatctgctcttgctattcggaatactgtcaaagatttacgag aagccttatgagagcgagttccattatacaactaagaatggggaggaaaggatctacagg agcaagggttactacgagctcgtcataactaactacagtagaaagctcttcgcggaaaag ataggccttgaaggctacaagatggagaagctcagcctcaagaagacgaaggttgaccag ccaattgtcacggttgagagcgttgaggtgcttggagaggaaatagtctatgacttcacg gttcccaattatcacatgtacataagcaacggcttcatgagccacaactgtggagaagag cctctatacgaatacgaatcctgtaacctcgcatcgatcaatttggccaagttcgtcaag tacgacgagaacggaaagccgtacttcgattgggatgaatatgcatacgtgattcaaaag gttgctaagtaccttgacaactccatagacgtcaacaagttcccgttgccagagatagat tacaacacgaagctgacgaggaggatcggagttggaatgatgggacttgccgatgcgctc ttcaagctgggaattccatacaacagcgaagaaggcttcaagttcatgaggaaagtcacc gaatacctaaccttctacgcctacaagtacagcgtcgaagctgccaagaagaggggaacc ttcccactctacgacaagaccgaatatccagagggtaagctacccgtggagggcttctac cacccagagatatggaaccttccatgggataagctcgtcgaggagataaagaagtatggg ctcaggaatgcaatggtcacgacgtgcccaccgaccggtagcgtttcgatgatagccgac acctcaagcggaattgaaccggtctatgcactcgtctacaagaagagtgttaccgttggt gaattctactacgtcgacccagtgttcgaggaagaacttaagaagagaggcctatacagc gaggagttgcttaagaagataagcgacaactacggctcagtccaggggctagaggagatt ccagaggacatgcaaagagtcttcgtgacggccctggacatacactggctcgaccacata atagcccaggcaagcattcagatgtggctgactgattcagcgagcaagacaataaatatg ataaacgaagcgacggttgaggatgttaaggcagcgtatctcatagcgagattcctggga tgcaagggagtaactgtctacagggatggttctctgagcgttcaagtgtacagcgtagag ggagaaaagaagaagagaagattcaagccaaagccaagtgagtacgccaagaagatattg cttgagatagtcgagaaagagccttggataaagaacttcataaacgttgatgagatactc aacggaaagaaagaacaactattgttctctctgagaccagctaatgagagtaaactaaaa gttccaggcagagaagaggaagtgagacctgggaatattccggaagaaaagataagagag ctccttggagtggtctactgtccagtgtgttacgagaaggaaggaaagctcgttgagctg aagatggaaagtggatgcgcgacctgtccagtctgtggatggagcaagtgcgttatcagc tga

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