Pyrococcus furiosus DSM 3638: PF0494
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Entry
PF0494 CDS
T00075
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
pfu
Pyrococcus furiosus DSM 3638
Brite
KEGG Orthology (KO) [BR:
pfu00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pfu03032
]
PF0494
03400 DNA repair and recombination proteins [BR:
pfu03400
]
PF0494
Enzymes [BR:
pfu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
PF0494
DNA replication proteins [BR:
pfu03032
]
Prokaryotic type
DNA Topoisomerases
PF0494
DNA repair and recombination proteins [BR:
pfu03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
PF0494
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Intein_splicing
Zn_ribbon_Top1
Toprim
Hint
DUF1064
ADK_lid
Motif
Other DBs
NCBI-ProteinID:
AAL80618
UniProt:
O73954
A0A5C0XMW2
LinkDB
All DBs
Position
510566..513748
Genome browser
AA seq
1060 aa
AA seq
DB search
MILVIAEKPNVARKIAMALAEVKPIKKTLFGVPYYELIRDGKRLIVASAVGHLYGLAPKN
DFFGYPIFDVEWVPVYIAEKGKEYAKDYIKLLSVLSKRVREFIVACDYDTEGEVIGYTAL
KYACGVDPGVAKRMKFSALTKRDLIKAWYNLEPTINFGMANAGIARHILDWYWGVNLSRA
LTHAIKRASGKWVVLSTGRVQGPTLKFLVDREREIQSFVPQPYWVIKLIFEKNGKKYTAN
YEKDKIWDENEAKRIVLEVKKAPARVTNIEVKQQNRNPPVPFDLGTLQREAYSAFGFSPK
KTLDIAQSLYEKGFCLHPDTLILTSQGVRKIKELSREGEVFALDFNLKLSKAKYRLLERD
ADEQMYKVTLLDGTELYLTADHPVLVYREGNLAFVPADKLRETDHVVLVLNKSARDNYGF
LDLLLEITDSQEDYAILENGETLSLHSLKMLVERGEIKDIAVVGFSHNNFGKVMLRDELW
YLIGYLAGKGGEIKGNGVVISSRTKEIVGLTKSLNIDLIETEEGIVLSNKSFVRLLHLIH
YTPRVPEVYGIINNTEWLKAFLAGYYDATLLEGLTLEALYKIKVYLQLLGIRAKIEDNKL
KVHLEDLQRFRELLGKFSRRKLYVETSQVPVFTDFDERSYDFPRILGGDIYIIGIKSIEK
FHYKGKVYDLVVENYHNFIANGIAVHNCSYPRTESQKLPKNLNYKFIIQNLARIPEYRPY
AHLLLGMPELKPVEGKKEDPAHPAIYPTGEIPRPGDLTKDEALLYDMIVRRFLAVFMEPA
VRETVKVTISAGKHKFFISGGRTVKEGWLRVYGKYVKFDEVTLPTFFIGERIKVLQVKRE
KKKTKPPARYSPAAVIKKMEDLGLGTKATRAQILETLYQRGYIEGKKSIKVTPLGMKVIE
TLEKYVPEIISVELTREFEKKMELIMEGKLTKEEVIEEAKIRLTKILEEFKKKELEIGLE
LAKIVVGEEKPPLIVGKCPKCGGDLIVKYNEKTGKRFVGCSNWPKCNVTYPILQRGEIIP
TNKTCCNGAPVVIIREKDGREWEICLDMNCKEYNTIKKKR
NT seq
3183 nt
NT seq
+upstream
nt +downstream
nt
atgatcctcgttattgcagagaagccaaacgttgctagaaaaatagcaatggcactagct
gaggtgaagcctattaagaaaactctctttggagttccctactacgagttaattagggat
ggaaaaagactcatagttgcctcagcagttggtcatttatacggtttagcccccaaaaat
gacttttttggatatccgatatttgatgtggaatgggttcctgtttacatagctgaaaaa
ggaaaagaatatgcaaaagattacattaagttgctttcagtcctatccaaaagggttaga
gaatttattgttgcctgtgactatgatactgaaggagaggtcattggttatactgcattg
aagtatgcctgtggcgtggatcctggggttgctaaaagaatgaaattttctgcattaact
aagagggacttaatcaaagcatggtacaatcttgagccaactataaactttggaatggca
aatgctggtattgccaggcatattttggactggtactggggggttaacctatcaagggcg
ttaacccatgcaataaagagggcgagtggaaagtgggttgtccttagtactggaagggta
caaggaccaacgctcaagttcttagttgatagagaaagggaaattcaaagctttgttccc
caaccttattgggtcataaagctgatatttgaaaagaatgggaaaaagtacacggcaaac
tacgaaaaggataagatttgggatgaaaatgaagcaaaaagaattgtattagaggtaaaa
aaggcccctgcaagggtaacaaatattgaagttaaacaacaaaataggaatccccctgtt
cccttcgacctgggaactcttcaaagggaagcctattccgcctttgggttttcaccaaag
aaaaccttagatatagctcagagtctttatgaaaagggattctgccttcacccggacacc
ttgatcttaacttcccagggggttaggaaaattaaagagttgtctcgagagggggaagtc
tttgctttggactttaatctaaagttgtcaaaagcaaagtataggcttctcgagcgtgat
gcagatgagcaaatgtataaagttacacttcttgacgggacggagttgtatttaacagca
gatcatccagttttagtgtacagagagggtaatttggcttttgtacccgctgataagctt
agagaaactgatcatgtggttttagtccttaataaatctgccagagataattatggattt
ttggatcttttacttgagataactgattcccaggaggattatgcaattctagagaatggt
gaaacactatcgttgcattccttaaaaatgcttgtggagaggggggaaataaaagacatt
gcagtggtcggattttcacacaataactttggtaaagtgatgttaagagatgagttgtgg
tacctcattggatatttagcaggaaagggaggagagatcaaaggtaatggagttgtaatc
agctctagaacaaaagaaattgttggtttaacaaaatctttaaacattgatttaattgaa
acagaagaaggaattgttttaagtaacaaatcatttgttagattactgcacctaattcat
tatactccacgtgttccagaagtttatggaataataaacaatactgagtggctaaaggct
tttttggctggatactacgacgcaactttacttgagggcttaactttggaggctctttac
aaaattaaagtttacctacagcttttgggtataagagcaaagattgaagataacaaactt
aaggttcacctggaagatctacaacgctttagagaacttcttggaaagtttagccggaga
aaattatatgtagaaacttcacaagttcctgtattcactgattttgacgaaagaagttat
gactttccaagaatacttggaggggatatctacattattggaataaagtcaatagagaaa
ttccactataaggggaaggtctatgatcttgtagttgaaaattaccacaacttcatagcc
aatggaattgcggttcacaactgttcttatcccaggacagaaagccaaaagctccccaag
aatctaaactataagtttatcattcagaacttagcgagaattccagagtacaggccttat
gcacacctactcctgggaatgcccgaacttaagccggtagaaggaaaaaaggaggatcct
gcccatccggccatttatccaacgggtgaaattcccaggcctggagatttaactaaagat
gaagctctgctttatgacatgattgttagaagattcttagcggtatttatggagccagca
gttagagaaaccgttaaagtcacaatttctgcaggaaagcacaagttcttcatttctgga
ggaagaacggttaaagaaggctggctgagggtgtatggaaagtatgttaagttcgatgaa
gttacacttccaacattcttcatcggtgagagaattaaagtccttcaagtaaagagagaa
aagaaaaagacgaagccccccgctagatactcccccgctgcagtcattaaaaagatggaa
gatttgggattgggcaccaaggccacaagagcccaaatacttgagaccctatatcagaga
ggatatatagaaggaaagaaatcgataaaggtaactcccctaggaatgaaagttatagaa
actctagaaaagtacgttccagaaataataagtgttgagttgactagagaatttgaaaag
aagatggaactaatcatggaaggtaaactaacaaaagaggaagtaatagaggaagccaaa
attaggcttacaaaaatacttgaagagttcaaaaagaaggagcttgaaataggtcttgaa
ctggcaaagattgtagttggggaagagaagcctccattaattgtagggaagtgccccaag
tgtggaggagacttaattgttaagtataacgaaaagactgggaagaggtttgtaggttgt
tctaattggccaaaatgtaatgttacatacccgattcttcagagaggggagattatacca
accaataaaacttgttgtaacggtgccccggtagttataattcgagaaaaagatggaaga
gaatgggagatatgtctagatatgaattgcaaggaatataatactattaagaaaaagaga
tag
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