Pyrococcus furiosus DSM 3638: PF0938
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Entry
PF0938 CDS
T00075
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pfu
Pyrococcus furiosus DSM 3638
Pathway
pfu00290
Valine, leucine and isoleucine biosynthesis
pfu00660
C5-Branched dibasic acid metabolism
pfu01100
Metabolic pathways
pfu01110
Biosynthesis of secondary metabolites
pfu01210
2-Oxocarboxylic acid metabolism
pfu01230
Biosynthesis of amino acids
Module
pfu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pfu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PF0938
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PF0938
Enzymes [BR:
pfu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PF0938
4.2.1.35 (R)-2-methylmalate dehydratase
PF0938
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AAL81062
UniProt:
Q8U2A1
A0A5C0XRX9
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All DBs
Position
902558..903832
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AA seq
424 aa
AA seq
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MGGMTIAEKILATHAGKEEVKPGEIVLAKVDFMFGNDVTTPLAIKTFRKIGVEKVFDPER
IAIVLDHFTPNKDIKAAEQCKFSREFAREQGIKWFFEGGNVGVEHCLLPELGLVLPGELI
IGADSHTCTYGALGAFATGVGSTDLAVAMATGEAWFRVPETIKFVYEGDLQPWVTSKDLI
LYTIGDIGVNGALYKVMEFSGEVIEKLSVEQRMTMTNMAIEAGAKTGIIEPDKKTIEYVK
GRAKREYKIYKSDEDAKYYKVIEYDVSKIEPQVAFPHLPENTVPISKAAKMNIKIDQVVI
GSCTNGRLEDLRMAAEVLEGQKVAPWVRLIILPCSPTVYFKAMKEGLLEIFLEAGAVIGP
PTCGPCLGGHMGILASGERAVSTTNRNFVGRMGHPKSEVYLASPYVAAASAILGRIASPE
EVVK
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgggcggaatgacaatagctgaaaaaattttggcaactcatgccggaaaggaagaggta
aaacctggagagatagttttggcaaaagtggacttcatgtttgggaatgatgtaacaacc
cccttagccataaaaacgtttagaaagattggagtggagaaggtttttgacccagaaaga
atagcaatagttttagatcacttcactccaaataaagatatcaaagctgcggagcaatgt
aaattctcacgagaatttgccagagaacagggaatcaagtggttctttgagggaggaaac
gttggtgtcgagcattgtttactccctgagttaggattagttctcccaggagagctaatt
attggagcagattcccacacttgcacttatggagccctgggtgcctttgcaactggagtt
ggtagtactgacttagcagttgcaatggcaacaggagaggcgtggttcagggttcccgaa
acgataaaattcgtttatgaaggagaccttcaaccctgggtaactagtaaggatctcata
ctttacacaatcggagacataggggttaatggagccctctacaaagtcatggaattttcg
ggagaagttatagagaagctttccgtggaacagaggatgacgatgactaatatggccata
gaggccggagcaaagactgggataatagagccggataagaagactatagagtacgtaaag
gggagggccaagagagagtacaagatctacaagagcgatgaagatgcaaagtactacaag
gttattgagtatgacgttagtaaaattgaacctcaagttgcctttccacacttacccgaa
aacacggttcccatcagcaaggccgcaaagatgaacataaagatagaccaagttgtcatt
ggctcatgtacgaatggtaggttggaagaccttagaatggccgctgaagttttagaaggc
cagaaagtggccccctgggtaaggcttatcattcttccatgttcaccgactgtgtatttc
aaggcaatgaaggagggcctcttggagattttcctggaggcaggagctgttatagggcct
ccaacttgtggaccgtgcctaggaggtcacatgggtattctggcgagtggtgagagagct
gtatctacaacaaacaggaactttgttggaagaatgggtcacccaaagagcgaagtttac
ttggcaagtccctatgtagctgcagcttcggctattcttggtagaattgcctctccagag
gaggtggtaaaatga
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